检索结果-南通市图书馆

Treatment of gastric remnant cancer post distal gastrectomy by endoscopic submucosal dissection using an insulation-tipped diathermic knife

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2008年第16期14卷 2550-2555页

作者： Shoji Hirasaki Hiromitsu Kanzaki Minoru Matsubara Kohei Fujitav shuji Matsumura Seiyuu Suzuki Second Department of Internal Medicine Sumitomo Besshi Hospital

AIM: To evaluate the effectiveness of endoscopic submucosal dissection using an insulation-tipped diathermic knife (IT-ESD) for the treatment of patients with gastric remnant cancer. METHODS: Thirty-two patients with early gastric cancer in the remnant stomach, who underwent distal gastrectomy due to gastric carcinoma, were treated with endoscopic mucosal resection (EMR) or ESD at Sumitomo Besshi Hospital and Shikoku Cancer Center in the 10-year period from January 1998 to December 2007, including 17 patients treated with IT-ESD. Retrospectively, patient backgrounds, the one-piece resection rate, complete resection (CR) rate, operation time, bleeding rate, and perforation rate were compared between patients treated with conventional EMR and those treated with IT-ESD. RESULTS: The CR rate (40% in the EMR group vs 82% in the IT-ESD group) was significantly higher in the IT-ESD group than in the EMR group; however, the operation time was significantly longer for the IT- ESD group (57.6 ± 31.9 min vs 21.1 ± 12.2 min). No significant differences were found in the rate of underlying cardiopulmonary disease (IT-ESD group, 12% vs EMR group, 13%), one-piece resection rate (100% vs 73%), bleeding rate (18% vs 6.7%), and perforation rate (0% vs 0%) between the two groups. CONCLUSION: IT-ESD appears to be an effective treatment for gastric remnant cancer post distal gastrectomy because of its high CR rate. It is useful for histological confirmation of successful treatment. Thelong-term outcome needs to be evaluated in the future.

关键词： Remnant stomach Distal gastrectomy Gastric cancer Endoscopic mucosal resection Insulationtipped diathermic knife

Small extracellular vesicles and liver diseases:From diagnosis to therapy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Hepatology 2022年第7期14卷 1307-1318页

作者： Atsunori Tsuchiya Kazuki Natsui Yui Ishii Yohei Koseki Nobutaka Takeda Kei Tomiyoshi Fusako Yamazaki Yuki Yoshida shuji Terai Division of Gastroenterology and Hepatology Niigata University Medical and Dental HospitalNiigata 951-8510Japan Department of Gastroenterology and Hepatology Niigata UniversityNiigata 951-8510Japan

Extracellular vesicles(EVs),especially small EVs(sEVs)derived from liver cells,have been the focus of much attention in the normal physiology and pathogenesis of various diseases affecting the *** are approximately 100 nm in size,enclosed within lipid bilayers,and are very *** lipids,proteins,and nucleic acids,including miRNAs,contained within these vesicles are known to play important roles in intercellular *** mini-review summarizes the application of ***,liver diseases and the related diagnostic markers are described,and the current active status of miRNA research in diagnosis of hepatocellular carcinoma(HCC)is ***,the biodistribution and pharmacokinetics of sEVs are described,and the liver is highlighted as the organ with the highest accumulation of ***,the relationship between sEVs and the pathogenesis of liver disorders is described with emphesis on the current active status of miRNA research in HCC recurrence and ***,the possibility of future therapy using sEVs from mesenchymal stem(stromal)cells for cirrhosis and other diseases is described.

关键词： Small extracellular vesicles Liver cirrhosis Hepatocellular carcinoma Mesenchymal stem cells

Detectability of Renal Arteries in Living Renal Donors Using Multi-Detector CT: Comparison among Axial and Three-Dimensional Reconstruction Images

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Medical Imaging 2013年第3期3卷 75-81页

作者： Mari Kohno Tsuyoshi Tajima Kazuya Omoto shuji Sakai Department of Diagnostic Imaging and Nuclear Medicine Tokyo Women’s Medical University Tokyo Japan Department of Radiology National Center for Global Health and Medicine Tokyo Japan Department of Urology Tokyo Women’s Medical University Tokyo Japan

Purpose: The purpose was to compare the effectiveness of MDCT reconstruction methods that improve detectability for detecting the renal arteries in patients undergoing laparoscopic nephrectomy irrespective of the ability of the radiologist. Methods: 128 patients with left nephrectomy and either one or multiple renal arteries were enrolled. Radiologists with varying levels of expertise (5 board-certified and 3 non-certified) interpreted all MDCT images, including axial, VR and MIP images, independently and determined the numbers of renal arteries. The interpretation times, sensitivity, specificity and diagnostic accuracy rates were analyzed. A receiver operating characteristic analysis was used to compare the results from the various reconstruction methods. Results: At surgery, there were 156 arteries: 101 donors had one renal artery and 27 had multiple arteries. The interpretation time for board-certified radiologists was shorter than that for non-certified radiologists, and the interpretation time using MIP images was significantly shorter than that of using the other reconstruction methods. The sensitivity, specificity and diagnostic accuracy on axial images were significantly higher than those on other images. The average Az value for detection of the numbers of renal arteries using axial images was higher than that of using other images. Conclusion: MDCT is helpful in reviewing the numbers of donated renal arteries for radiologists with different levels of expertise, and different types of reconstructions.

关键词： Renal Transplantation Laparoscopic Nephrectomy MDCT Renal Arteries The ROC Analyses

CREATE TRANSGENIC RABBITS BY MICROINJECTING HUMAN apoA-Ⅱ GENE INTO FERTILIZED EGGS

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Pharmaceutical Analysis 2004年第1期16卷 67-70页

作者：刘恩岐 shuji Kitajima Masatoshi Morimoto Laboratory Animal Center Center for Laboratory Animals

Objective To create transgenic rabbits by microinjecting human apolipoprotein A-Ⅱ (apoA-Ⅱ) gene into one-cell embryos, to study apoA-Ⅱ gene function on plasma lipoprotein metabolism and atherosclerosis. Methods Superovulation and synchronization of estrus were induced in female Japanese White Rabbits by injecting hormone, then mating with male. After collected the fertilized eggs, the human apoA-Ⅱ gene was microinjected into the male pronucleus of eggs. The injected eggs were transferred into recipient female rabbits. Last, extract DNA from the new borns ear and determine whether the newborns were transgenic by polymerase chain reaction (PCR) or Southern blot analysis. Results A total of 822 embryos with microinjection of human apoAⅡ gene were implanted into 28 recipient rabbits. The number of surviving newborns was 37. 3 transgenic positive surviving founders were found with human apoA-Ⅱ.

关键词： transgenic rabbit microinjection apoA-Ⅱ

坦博拉火山爆发与中国社会历史——本专题解说

在线全文

学校读者我要写书评

暂无评论

学术界 2009年第5期 37-41页

作者：曹树基上海交通大学历史系上海200240

19世纪上半叶,中国人口出现了一些值得注意的现象,刘翠溶指出：“我们虽然也看到1750年轮的平均死亡年龄较以前的年轮为低,由于受家族记录断限的限制,我们并不能肯定死亡率的确是在十九世纪逐渐增高。如果真的是如此,那么,死亡率的增高... 详细信息

19世纪上半叶,中国人口出现了一些值得注意的现象,刘翠溶指出：“我们虽然也看到1750年轮的平均死亡年龄较以前的年轮为低,由于受家族记录断限的限制,我们并不能肯定死亡率的确是在十九世纪逐渐增高。如果真的是如此,那么,死亡率的增高、未婚率的提高和生子率的略降,竟然在时间上巧合,都是发生在清代由盛转衰之际。这是值得注意的人口现象。”

关键词：中国人口社会历史火山爆发 19世纪上半叶解说专题死亡年龄十九世纪

Case of severe alcoholic hepatitis treated with granulocytapheresis

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2016年第11期4卷 369-374页

作者： Yukari Watanabe Kenya Kamimura Tomohiro Iwasaki Hiroyuki Abe Shunsaku Takahashi Ken-ichi Mizuno Manabu Takeuchi Atsushi Eino Ichiei Narita shuji Terai Division of Gastroenterology and Hepatology Graduate School of Medical and Dental SciencesNiigata University Japan Labor Health and Welfare Organization Tsubame Rosai Hospital Division of Clinical Nephrology and Rheumatology Graduate School of Medical and Dental SciencesNiigata University

Severe alcoholic hepatitis(AH) has a high mortality,and it is associated with encephalopathy,acute renal failure,sepsis,gastrointestinal bleeding,and *** 28-d mortality remains poor(34%-40%),because no effective treatment has been ***,corticosteroids(CS) have been considered effective for significantly improving the prognosis of those with AH,as it prevents the production of pro-inflammatory ***,CS are not always appropriate as an initial therapeutic option,such as in cases with an infection or resistance to *** describe a patient with severe AH complicated by a severe infection caused by the multidrug resistance bacteria(Pseudomonas aeruginosa),and was successfully treated with granulocytapheresis monotherapy without using *** experience of this case will provide understanding of the disease and information treating cases without using CS.

关键词： Apheresis Hepatitis Alcoholic Alcoholic hepatitis Case reports

Colorectal neuroendocrine carcinoma: A case report and review of the literature

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2019年第14期7卷 1865-1875页

作者： Tomoaki Yoshida Kenya Kamimura Kazunori Hosaka Koji Doumori Hiromitsu Oka Akito Sato Yasuo Fukuhara Shoji Watanabe Tomomi Sato Akira Yoshikawa Takashi Tomidokoro shuji Terai Division of Gastroenterology and Hepatology Graduate School of Medical and Dental SciencesNiigata UniversityNiigata 951-8510Japan Division of Gastroenterology and Hepatology Nagaoka Chuo General HospitalNiigata 940-0861Japan

BACKGROUND Colorectal neuroendocrine carcinoma (NEC) is a rare tumor that demonstrates aggressive growth pattern with ingrowth into the tract, metastasis to the other organs, and invasion to the surrounding organs;these clinical characteristics result in poor prognosis. Surgical resection appears as an effective approach;however, because it is difficult to accurately diagnose NEC during the early stage and owing to its aggressive growth pattern, development of a reliable standard chemotherapy regimen and management strategies are essential. CASE SUMMARY Here, we report the case of patient with NEC showing an aggressive growth pattern that resulted in the rupture of the tumor to the outside the colon after stenting of the internal colonic stenosis. In addition, the tumor invaded into the duodenum, thereby causing duodenal stenosis that required an additional stent in the duodenum. This aggressive growth pattern is one of the main features of the NEC that is different from adenocarcinoma. To clarify the clinical characteristics, we reviewed 60 recently reported cases, including data on tumor location, size, treatment, and prognosis. CONCLUSION We consider that the information presented here is of great significance for the diagnosis, treatment, and management of symptoms of the patients with NEC.

关键词： Neuroendocrine carcinoma Colon Colorectal mixed adenoneuroendocrine carcinoma Growth Case report

Usefulness of ultrasonography to assess the response to steroidal therapy for the rare case of type 2b immunoglobulin G4-related sclerosing cholangitis without pancreatitis:A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2020年第22期8卷 5821-5830页

作者： Yuto Tanaka Kenya Kamimura Ryota Nakamura Marina Ohkoshi-Yamada Yohei Koseki Takeshi Mizusawa Satoshi Ikarashi Kazunao Hayashi Hiroki Sato Akira Sakamaki Junji Yokoyama shuji Terai Division of Gastroenterology and Hepatology Graduate School of Medical and Dental SciencesNiigata UniversityNiigata 9518510Japan

BACKGROUND A type 2b immunoglobulin G4(IgG4)-related sclerosing cholangitis(SC)without autoimmune pancreatitis is a rare condition with *** the variety of the imaging modalities have tested its usefulness in diagnosing the IgG4-SC,however,the usage of ultrasonography for the assessment of the response to steroidal therapy on the changes of bile duct wall thickness have not been reported in the ***,the information of our recent case and reported cases have been *** SUMMARY We report the case of an 82-year-old Japanese man diagnosed with isolated IgG4-related SC based on the increase of serum IgG4,narrowing of the bile duct,its wall thickness,no complication of autoimmune pancreatitis,and IgG4 positive inflammatory cell infiltration to the wall with the fibrotic *** cholangiogram revealed type 2b according to the *** treatment showed a favorable effect,with the smooth decrease in serum IgG4 and the improvement of the bile duct wall *** As isolated type 2b,IgG4-SC is rare,the images,histological findings,and clinical course of our case will be helpful for physicians to diagnose and treat the new cases appropriately.

关键词： Immunoglobulin G4-related sclerosing cholangitis Type 2b Corticosteroid Autoimmune pancreatitis Ultrasonography Imaging Case report

Effects of Al-Ti-B-RE grain refiner on microstructure and mechanical properties of Al-7.0Si-0.55Mg alloy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Transactions of Nonferrous Metals Society of China 2014年第7期24卷 2244-2250页

作者：王雪姣徐聪 Arfan MUHAMMAD shuji HANADA Hiroshi YAMAGATA 王文红马朝利北京航空航天大学材料科学与工程学院空天先进材料与服役教育部重点实验室北京100191 Institute for Materials Research Tohoku University Center for Advanced Die Engineering and Technology Gifu University 河北四通新型金属材料股份有限公司保定071105

To investigate the effects of Al-Ti-B-RE grain refiner on microstructure and mechanical properties of Al-7.0Si-0.55Mg （A357） alloy, some novel Al-7.0Si-0.55Mg alloys added with different amount of Al-STi-1B-RE grain refiner with different RE composition were prepared by vacuum-melting. The microstructure and fracture behavior of the AI-7.0Si-0.55Mg alloys with the grain refiners were observed by X-ray diffraction （XRD）, optical microscopy （OM）, scanning electron microscopy （SEM）, and the mechanical properties of the alloys were tested in mechanical testing machine at room temperature. The observation of AI-Ti-B-RE morphology and internal structure of the particles reveals that it exhibits a TiAl3/Ti2Al20RE core-shell structure via heterogeneous TiB2 nuclei. The tensile strength of Al-7.0Si-0.55Mg alloys with Al-5Ti-1B-3.0RE grain refiner reaches the peak value at the same addition （0.2%） of grain refiner.

关键词： A357 alloy Al-5Ti-1B grain refiner rare earth fracture refining effect tensile strength