Usefulness of ultrasonography to assess the response to steroidal therapy for the rare case of type 2b immunoglobulin G4-related sclerosing cholangitis without pancreatitis:A case report

作     者：Yuto Tanaka Kenya Kamimura Ryota Nakamura Marina Ohkoshi-Yamada Yohei Koseki Takeshi Mizusawa Satoshi Ikarashi Kazunao Hayashi Hiroki Sato Akira Sakamaki Junji Yokoyama Shuji Terai 

作者机构：Division of Gastroenterology and HepatologyGraduate School of Medical and Dental SciencesNiigata UniversityNiigata 9518510Japan 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2020年第8卷第22期

页      面：5821-5830页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Immunoglobulin G4-related sclerosing cholangitis Type 2b Corticosteroid Autoimmune pancreatitis Ultrasonography Imaging Case report 

摘      要：BACKGROUND A type 2b immunoglobulin G4(IgG4)-related sclerosing cholangitis(SC)without autoimmune pancreatitis is a rare condition with *** the variety of the imaging modalities have tested its usefulness in diagnosing the IgG4-SC,however,the usage of ultrasonography for the assessment of the response to steroidal therapy on the changes of bile duct wall thickness have not been reported in the ***,the information of our recent case and reported cases have been *** SUMMARY We report the case of an 82-year-old Japanese man diagnosed with isolated IgG4-related SC based on the increase of serum IgG4,narrowing of the bile duct,its wall thickness,no complication of autoimmune pancreatitis,and IgG4 positive inflammatory cell infiltration to the wall with the fibrotic *** cholangiogram revealed type 2b according to the *** treatment showed a favorable effect,with the smooth decrease in serum IgG4 and the improvement of the bile duct wall *** As isolated type 2b,IgG4-SC is rare,the images,histological findings,and clinical course of our case will be helpful for physicians to diagnose and treat the new cases appropriately.