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Journal of Modern Power Systems and Clean Energy 2022年第5期10卷 1385-1400页

作者： Ruohuan Yang Jianxun Jin Qian Zhou shuai mu Ahmed Abu-Siada IEEE School of Electrical and Information Engineering Tianjin UniversityTianjin 300072China Department of Electrical and Computer Engineering Curtin UniversityPerthWA 6102Australia

The development of DC custom power protection devices is still in infancy that confines the sensitive loads integrated into medium-voltage(MV) and low-voltage(LV) DC networks. Considering the DC doubly-fed induction generator(DCDFIG) based wind energy conversion system(WECS), this paper proposes a dual active bridge(DAB) based DC unified power quality conditioner(DC-UPQC) with the integration of superconducting magnetic energy storage(SMES) to maintain the terminal voltage of DC-DFIG and regulate the current flow. The principle of the proposed DC-UPQC has three parts, i.e., parallel-side DAB(PDAB), series-side DAB(SDAB), and SMES,used for the voltage compensation, current and power regulation, and energy storage, respectively. The circuit principle of the PDAB and SDAB and the modeling of SMES are analyzed in this paper. A DC dual control strategy is also proposed to deal with the DC voltage oscillation generated by the AC-side asymmetrical fault. A case study of DC-DFIG interfaced with DC power grid is carried out, integrated with the proposed SMES-based DC-UPQC to verify the high-power applications of the proposed structure. Finally, an experiment is implemented, and the results demonstrate the correctness of the theoretical analysis and the feasibility of the proposed structure.

关键词： DC network unified power quality conditioner(UPAC) DC doubly-fed induction generator(DC-DFIG) power quality

Synthesis and biological evaluation of novel derivatives of desloratadine

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Chinese Chemical Letters 2013年第6期24卷 531-534页

作者： shuai mu Xiao-shuai Xie Duan Niu Da-shuai Zhang Deng-Ke Liu Chang-Xiao Liu School of Chemical Engineering and Technology Tianjin University State Key Laboratory of Drug Delivery Technology and Pharmacokinetics Tianjin Institute of Pharmaceutical Research Graduate School of Tianjin Medical University Tianjin Key Laboratory of Molecular Design and Drug Discovery Tianjin Institute of Pharmaceutical Research

Series of novel derivatives of desloratadine designed as arginine vasopressin receptor antagonists were synthesized and structurally characterized by melting points,^1H NMR and *** in vivo diuretic activities were evaluated on rats,and several target compounds showed promising diuretic results, especially compounds 8,18,27 and *** in vitro bonding assay and cAMP assay showed that these compounds had a higher affinity to vasopressin V2 receptor than VI a *** studies indicated that desloratadine may be an active substructure for novel arginine vasopressin receptor antagonist development.

关键词： Derivatives of desloratadine Arginine vasopressin receptor antagonists Diuretic activity

Quantum classifier with parameterized quantum circuit based on the isolated quantum system

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The Journal of China Universities of Posts and Telecommunications 2022年第4期29卷 21-31页

作者： Shi Jinjing Wang Wenxuan Xiao Zimeng mu shuai Li Qin School of Computer Science and Engineering Central South UniversityChangsha 410083China School of Computer Science and School of Cyberspace Science Xiangtan UniversityXiangtan 411301China

It is a critical challenge for quantum machine learning to classify the datasets *** article develops a quantum classifier based on the isolated quantum system(QC-IQS)to classify nonlinear and multidimensional ***,a model of QC-IQS is presented by creating parameterized quantum circuits(PQCs)based on the decomposing of unitary operators with the Hamiltonian in the isolated quantum ***,a parameterized quantum classification algorithm(QCA)is designed to calculate the classification results by updating the loss function until it ***,the experiments on nonlinear random number datasets and Iris datasets are designed to demonstrate that the QC-IQS model can handle and generate accurate classification results on different kinds of *** experimental results reveal that the QC-IQS is adaptive and learnable to handle different types of ***,QC-IQS compensates the issue that the accuracy of previous quantum classifiers declines when dealing with diverse *** promotes the process of novel data processing with quantum machine learning and has the potential for more comprehensive applications in the future.

关键词： quantum classifier quantum classification isolated quantum system parameterized quantum circuit Hamiltonian

Strategies for culturing active/dormant marine microbes

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Marine Life Science & Technology 2021年第2期3卷 121-131页

作者： Da-shuai mu Yang Ouyang Guan-Jun Chen Zong-Jun Du State Key Laboratory of Microbial Technology Institute of Microbial TechnologyShandong UniversityQingdao266237China Marine College Shandong UniversityWeihai264209China Institute for Environmental Genomics University of OklahomaNormanOKUSA

Microorganisms are ubiquitous in the ocean environment and they play key roles in marine ecosystem function and ***,many of their functions and phenotypes remain unknown because indigenous marine bacteria are mostly difficult to *** many novel techniques have brought previously uncultured microbes into laboratory culture,there are still many most-wanted or key players that need to be cultured from marine *** review discusses possible reasons for‘unculturable microbes’and categorizes uncultured bacteria into three groups:dominant active bacteria,rare active bacteria,and dormant *** review also summarizes advances in cultivation techniques for culturing each group of unculturable *** the natural environment is an effective strategy for isolating dominant active bacteria,whereas culturomics and enrichment culture methods are proposed for isolating rare active *** dormant bacteria,resuscitation culture is an appropriate ***,the review provides a list of the most-wanted bacteria and proposes potential strategies for culturing these bacteria in marine *** review provides new insight into the development of strategies for the cultivation of specific groups of uncultured bacteria and therefore paves the way for the detection of novel microbes and their functions in marine ecosystems.

关键词： Uncultured marine bacteria Culture strategies Dominant active bacteria Rare active bacteria Dormant bacteria Most-wanted bacteria

Synthesis and biological evaluation of novel phenothiazine derivatives as non-peptide arginine vasopressin V2 receptor antagonists

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Chinese Chemical Letters 2015年第5期26卷 627-630页

作者： Shuang Zhi shuai mu Ying Liu Min Gong Ping-Bao Wang Deng-Ke Liu School of Chemical Engineering and Technology Tianjin University Tianjin Institute of Pharmaceutical Research

A series of novel phenothiazine derivatives was synthesized and tested for arginine vasopressin receptor antagonist activity. They were synthesized as novel arginine vasopressin receptor antagonists from phenothiazine as a scaffold via successive acylation, reduction and acylation reactions. Their structures were characterized by ^1H NMR, ^13C NMR and HRMS, and biological activity was evaluated by in vitro and in vivo studies. The in vitro binding assay indicated that several compounds are potent selective V2 receptor antagonists. Compounds with promising binding affinity to V2 receptors were selected to conduct the in vivo diuretic studies on Sprague-Dawley rats. Among them, 1n, 1r, It and 1v exhibited excellent diuretic activity, especially 1 r and 1v. Therefore, 1 r and 1v are potent novel AVP V2 receptor antagonist candidates.

关键词： Arginine vasopressin V2 receptor antagonist Phenothiazine derivatives Synthesis Biological activities

Zip： An Algorithm Based on Loser Tree for Common Contacts Searching in Large Graphs

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Journal of Computer Science & Technology 2015年第4期30卷 799-809页

作者：唐宏牟帅黄晋朱佳陈健丁蕊 School of Information Science and Technology Sun Yat-sen University Guangzhou 510006 China School of Software Engineering South China University of Technology Guangzhou 510006 China School of Computer Science South China Normal University Guangzhou 510631 China

The problem of k-hop reachability between two vertices in a graph has received considerable attention in recent years. A substantial number of algorithms have been proposed with the goal of improving the searching e？ciency of the k-hop reachability between two vertices in a graph. However, searching and traversing are challenging tasks, especially in large-scale graphs. Furthermore, the existing algorithms propounded by different scholars are not satisfactory in terms of feasibility and scalability when applied to different kinds of graphs. In this work, we propose a new algorithm, called Zip, in an attempt to e？ciently determine the common contacts between any two random vertices in a large-scale graph. First, we describe a novel algorithm for constructing the graph index via binary searching which maintains the adjacent list of each vertex in order. Second, we present the ways to achieve a sequential k-hop contact set by using the loser tree, a merge sorting algorithm. Finally, we develop an e？cient algorithm for querying common contacts and an optimized strategy for k-hop contact set serialization. Experimental results on synthetic and real datasets show that the proposed Zip algorithm outperforms existing state-of-the-art algorithms （e.g., breadth-first searching, GRAIL, the graph stratification algorithm）.

关键词： common contact k-hop query reachability social network

Rice ZIP4 is essential for preferentially transport of zinc to new developing tissues and their development

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Rice ZIP4 is essential for preferentially transport of zinc ...

Cultivating the uncultured:Harnessing the“sandwich agar plate”approach to isolate heme-dependent bacteria from marine sediment

第七届长三角植物科学研讨会暨青年学术报告会

作者： shuai mu Le Luo Luqing Zheng College of Life Sciences Nanjing Agricultural University College of Resources and Environmental Sciences Nanjing Agricultural University

New developing tissues such as the shoot apical meristem(SAM) and the axillary meristems with low transpiration require high Zn levels for their active growth,but the molecular mechanisms underlying the preferential distribution to these tissues are poorly ***,Os ZIP4,a member of the ZIP(ZRT,IRT-like protein),showed high expression in the basal node,tiller bud and shoot SAM at the vegetative stage,but higher expression was also found in the node I at the reproductive stage of rice(Oryza sativa).Immunostaining revealed that OsZIP4 was localized at the phloem parenchyma cells and phloem transfer cells of enlarged and diffuse vascular bundles in both basal and upper *** of Os ZIP4 resulted in significant decrease in development of the tiller buds,but increase in Zn levels were observed in the shoot basal region at tillering *** only less Zn levels in the young panicles at panicle initiation(PT) stage but also in the flag leaf blade and in brown rice during the reproductive growth stage in the knockout lines as compared with the wild-type rice.A short-term experiment with the Zn stable isotope showed that more Zn was distributed to the *** short,OsZIP4 located in the node is responsible for unloading Zn from the phloem of enlarged vascular bundles,which is playing an important role in preferential distribution of zinc to the developing tissues in rice..

关键词： Zinc ZIP transporter distribution tiller bud rice

来源： cnki会议评论

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mLife 2024年第1期3卷 143-155页

作者： Jing Zhang Qi-Yun Liang Da-shuai mu Fengbai Lian Ya Gong Mengqi Ye Guan-Jun Chen Yuqi Ye Zong-Jun Du State Key Laboratory of Microbial Techlogy Insttute of Micrbial TchnoogyShandong UniversityQingdaoChina Marine College Shandong UniverstyWeihaiChina Shandong University-Weihai Research Institute of Industrial Technology WeihaiChina

In the classical microbial isolation technique,the isolation process inevitably destroys all microbial interactions and thus makes it difficult to culture the many microorganisms that rely on these interactions for *** this study,we designed a simple coculture technique named the“sandwich agar plate method,”which maintains microbial interactions throughout the isolation and pure culture *** total yield of uncultured species in sandwich agar plates based on eight helper strains was almost 10-fold that of the control *** uncultured species displayed commensal *** study found that heme was the growth-promoting factor of some marine commensal *** genomic analysis revealed that heme auxotrophies were common in various biotopes and prevalent in many uncultured microbial ***,our study supported that the survival strategies of heme auxotrophy in different habitats varied *** findings highlight that cocultivation based on the“sandwich agar plate method”could be developed and used to isolate more uncultured bacteria.

关键词： cultivation growth factors heme sandwich agar plate uncultured bacteria

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活性传感类荧光探针及其应用

分析试验室 2022年第12期41卷 1411-1424页

作者：穆帅张海霞甘肃省有色金属化学与资源利用重点实验室兰州大学化学化工学院兰州730000

荧光探针具有灵敏度高、操作简单、响应时间快等优点,在光学成像和分析传感等领域受到了广泛关注。小分子荧光探针在其开发的早期阶段,主要基于分子识别和主客体化学用于分析物的定量测定。近年来,基于小分子活性传感的荧光探针成为生... 详细信息

荧光探针具有灵敏度高、操作简单、响应时间快等优点,在光学成像和分析传感等领域受到了广泛关注。小分子荧光探针在其开发的早期阶段,主要基于分子识别和主客体化学用于分析物的定量测定。近年来,基于小分子活性传感的荧光探针成为生物传感和成像领域的研究热点。该类探针利用化学特异性反应代替分子识别原理检测分析物。本文详细介绍了活性传感探针的起源,阐述了该类探针的作用机理和设计原则,从氧化、还原以及非氧化还原反应类型方面概括介绍了活性传感类荧光探针,并对其发展进行了总结与展望。

关键词：活性传感荧光探针光谱检测

Short‑chain fatty acids(SCFAs)as potential resuscitation factors that promote the isolation and culture of uncultured bacteria in marine sediments

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Marine Life Science & Technology 2023年第3期5卷 400-414页

作者： Chun-Shui Sun Liu-Yan Zhou Qi-Yun Liang Xiao-Man Wang Yi-Xuan Lei Zhen-Xing Xu Feng-Qing Wang Guan-Jun Chen Zong-Jun Du Da-shuai mu Marine College Shandong UniversityWeihai 264209China State Key Laboratory of Microbial Technology Institute of Microbial TechnologyShandong UniversityQingdao 266237China Weihai Research Institute of Industrial Technology of Shandong University Weihai 264209China Institute of Microbiology Applications Xinjiang Academy of Agricultural SciencesUrumqi 830000China Tancheng County Inspection and Testing Center Tancheng 276100China Department of Applied Biological Chemistry Graduate School of Agricultural and Life SciencesThe University of TokyoBunkyo-KuTokyo 113-8657Japan Max Planck Institute for Marine Microbiology Celsiusstraße 128359 BremenGermany

Many marine bacteria are difcult to culture because they are dormant,rare or found in *** culturing has been widely tested as an important strategy to isolate rare or dormant ***,many more mechanisms remain ***,based on 16S rRNA gene high-throughput sequencing and metabolomics technology,it was found that the short-chain fatty acids(SCFAs)in metabolites were signifcantly correlated with uncultured bacterial groups during enrichment cultures.A pure culture analysis showed that the addition of SCFAs to media also resulted in high efciency for the isolation of uncultured strains from marine *** a result,238 strains belonging to 10 phyla,26 families and 82 species were successfully *** uncultured rare taxa within Chlorobi and Kiritimatiellaeota were successfully *** the newly isolated uncultured microbes,most genomes,***,possess SCFA oxidative degradation genes,and these features might aid these microbes in better adapting to the culture media.A further resuscitation analysis of a viable but non-culturable(VBNC)Marinilabiliales strain verifed that the addition of SCFAs could break the dormancy of Marinilabiliales in 5 days,and the growth curve test showed that the SCFAs could shorten the lag phase and increase the growth ***,this study provides new insights into SCFAs,which were frst studied as resuscitation factors in uncultured marine ***,this study can help improve the utilisation and excavation of marine microbial resources,especially for the most-wanted or key players.

关键词： Marine bacteria SCFAs VBNC Resuscitation culture