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Microstructure and shear properties evolution of Mn-doped SAC solder joint under isothermal aging

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Journal of Iron and Steel Research International 2023年第8期30卷 1650-1660页

作者： cheng-ming Li shu-jin chen Shan-shan Cai Ju-bo Peng Xiao-jing Wang Ying-wu Wang School of Material Science and Engineering Jiangsu University of Science and TechnologyZhenjiang 212003JiangsuChina R&D Center Yunnan Tin Group(Holding)Co.Ltd.Kunming 650000YunnanChina Modern School of Engineering Yunnan UniversityKunming 650091YunnanChina

The effects of Mn addition(0.005,0.01,0.03,0.05,and 0.07 wt.%)on microstructure,shear mechanical behavior,and interfacial thermal stabilities of SAC305 joints were investigated under isothermal aging temperatures of 170 C with different aging time(0,250,500,and 750 h).It is found that Mn addition can increase fracture energy of joints without decreasing the shear *** the microstructures have transformed from the eutectic net-like structure in SAC305 solder joints into the structures based onβ-Sn matrix with intermetallic compounds(IMCs)*** doping 0.07 wt.%Mn,the Cu_(6)Sn_(5) growth along the SAC305/Cu interface during thermal aging can be inhibited to some *** isothermal aging at 170°C,the maximum shear force of solder joint decreases continuously with aging time increasing,while the fracture energy rises first and then decreases,reaching the maximum at 500 h compared by that with the microstructure ***_(3)Sn growth between Cu_(3)Sn_(5)/Cu interface has been retarded most at the aging time of 250 h with 0.07 wt.%Mn-doped *** the aging time prolonging,the inhibition effect of Mn on CusSn IMC layer becomes *** strengthening effect of Mn can be explained by precipitation strengthening,and its mechanical behavior can be predicted by particle strengthening model proposed by Orowan.

关键词： SAC305 solder Mn doping Shear mechanical behavior Isothermal aging Interfacial intermetallic compound

Research of multilayers in EUV, soft X-ray and X-ray

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光学精密工程 2005年第4期13卷 512-518页

作者： WANG Zhan-shan WANG Feng-li ZHANG Zhong WANG Hong-chang WU Wen-juan ZHANG shu-min XU Yao GU Zhong-xiang chenG Xin-bin L1 Cun-xia WU Yong-rong WANG Bei QIN shu-jin chen Ling-yan Institute of Precision Optical Engineering Department of Physics Tongji University Shanghai 200092 China

To develop beam splitters for soft X-ray laser Michelson interferometer at 13.9 nm, Mo/Si multilayers of 100 nm thickness deposited on both sides of silicon nitride were fabricated by using DC magnetron sputtering. Initial evaluation of their reflectivity and transmission showed that reflectivity and transmission were above 10% and 25%. The broadband analyzers have been designed, fabricated and characterized for 13～20 nm polarization measurements. The measured results are in good agreement with the design. The supermirrors with different angular intervals at 0.154 nm have been designed, fabricated and characterized.

关键词： EUV X射线多层性激光宽带光纤

Acupuncture on Gnosia and Acetylcholinesterase in Senile Dementia Patients

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Journal of Acupuncture and Tuina Science 2003年第1期1卷 25-27页

作者： TANG Yong YU shu-guang chen jin ZHANG Wei chengdu University of Traditional Chinese Medicine Sichuan 610075 China Chengdu University of Traditional Chinese Medicine Sichuan 610075 China Chengdu University of Traditional Chinese Medicine Sichuan 610075 China Chengdu University of Traditional Chinese Medicine Sichuan 610075 China

Purpose To observe the effect of acupuncture on gnosia and acetylcholinesterase in patients with senile *** Eight patients diagnosed with mild or moderate senile dementia were treated by acupuncture of Sishencong (Ex-HN 1), Shenmen (HT 7) and Taixi (Kl 3) for 1 month; gnosia was evaluated by Mini-mental state examination before and after the treatment; plasma acetylcholin esterase activity was measured by fluorier before and after the *** There was a significant difference in gnosia between pre- and post-treatment with acupuncture (P0.05).Conclusion Acupuncture has a certain improving effect on gnosia in senile dementia; one month’s acupuncture treatment had little effect on plasma acetyl-cholinesterase activity. Key Words Dementia, Senile - Acupuncture therapy - Gnosia Author: Tang Yong (1974-), male, attending physician and doctor

关键词： Dementia, Senile Acupuncture therapy Gnosia

APPLICATION OF TRIANGLE MARKOV CHAIN TO GRAVITY CONCENTRATION

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Acta Metallurgica Sinica(English Letters) 1990年第8期3卷 81-90页

作者： WANG Weixing HUANG shu chen jin Central South University of Technology,Changsha,China WANG Weixing,Department of Mineral Engineering,Central South University of Technology,Changsha,Hunan 410083,China

In combination with the Bagnold's shearing theory and the principle of Markov process,a mathematical model of sluice type's gravity concentrators has been developed based on the transfer probabilities of mineral *** to the transfer probabilities,the quanti- tative relationship between the final separation results and feed variables has been established and verified by experimental *** availability of this model is vital for process design and optimization or mill control of gravity concentration circuits.

关键词： gravity concentration mineral processing stochastic process Markov process sediment transport

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基于新金融视角的第三方支付与通货膨胀分析

商业研究 2017年第10期 23-30页

作者：李淑锦陈莹杭州电子科技大学经济学院杭州310018

基于互联网金融发展的视角将第三方支付引入通货膨胀形成机制,利用Bootstrap方法和2008年第1季度-2016年第2季度的时间序列季度数据,分析第三方支付如何通过改变货币供应量和货币流通速度影响通货膨胀。结果表明,第三方互联网支付使用... 详细信息

基于互联网金融发展的视角将第三方支付引入通货膨胀形成机制,利用Bootstrap方法和2008年第1季度-2016年第2季度的时间序列季度数据,分析第三方支付如何通过改变货币供应量和货币流通速度影响通货膨胀。结果表明,第三方互联网支付使用率和央行规范互联网支付事件对通货膨胀的影响是显著的;货币流通速度与通货膨胀显著正相关,狭义货币乘数与通货膨胀呈正相关,但并不显著;产出缺口、资产价格和货币政策对通货膨胀有一定影响,但并不显著。上述结论说明,在互联网金融迅速发展的今天,第三方支付对通货膨胀的影响不可忽视。

关键词：第三方支付通货膨胀货币供应量货币流通速度

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论图书馆精神与图书馆价值观

图书馆论坛 2005年第5期25卷 4-10页

作者：曹树金陈忆金中山大学资讯管理系广东广州510275

对国内图书馆界关于图书馆精神的定义及具体内涵做了简要的述评,指出人们所说的图书馆精神主要包括图书馆价值观和图书馆职业道德两个方面;在回顾国内外现有图书馆价值观研究成果的基础上,提出“为人们自由、平等、便利地利用信息和... 详细信息

对国内图书馆界关于图书馆精神的定义及具体内涵做了简要的述评,指出人们所说的图书馆精神主要包括图书馆价值观和图书馆职业道德两个方面;在回顾国内外现有图书馆价值观研究成果的基础上,提出“为人们自由、平等、便利地利用信息和知识服务”的当代图书馆价值观及相关的支撑因素。

关键词：图书馆精神图书馆价值观

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结合高斯混合模型的关联分类离散化算法研究

小型微型计算机系统 2018年第4期39卷 732-737页

作者：吴辰文郭叔瑾李晨阳兰州交通大学电子与信息工程学院兰州730070

大多数以规则为基础的分类不能直接处理像血压这一类连续数据.离散化数据预处理可以将连续的数据转变成分类格式.现有的离散化算法没有考虑到数据集中连续变量的多模态分类密度,这可能会降低以规则为基础的分类器性能.提出一种新的基于... 详细信息

大多数以规则为基础的分类不能直接处理像血压这一类连续数据.离散化数据预处理可以将连续的数据转变成分类格式.现有的离散化算法没有考虑到数据集中连续变量的多模态分类密度,这可能会降低以规则为基础的分类器性能.提出一种新的基于高斯混合模型的离散化算法(Discretization Algorithm based on Gaussian Mixture Model,DAGMM),通过考虑连续变量的多峰分布以保留数据的原始模式.DAGMM算法的有效性通过4个公开可用的医疗数据集进行验证.实验结果表明,在产生的规则数和关联分类算法的分类准确度方面,DAGMM算法优于其它6个静态离散化算法.因此,在临床专家系统中运用此方法,有潜力提高以规则为基础的分类器的性能.

关键词：离散化关联分类算法规则归纳算法高斯混合模型

MicroRNA对EMT的调节作用及其与肿瘤侵袭的关系

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中国生物化学与分子生物学报 2016年第11期32卷 1197-1205页

作者：何姝槿陈厚文熊丽霞南昌大学医学部病理生理学教研室南昌330006 南昌大学第二临床医学院南昌330006

上皮间质转化(epithelial-mesenchymal transition,EMT)是指上皮细胞表型由上皮向间质转换的生物学过程,可发生在生理过程中促进发育、组织愈合和修复。近年对肿瘤的研究发现,EMT与肿瘤的发生发展密切相关。肿瘤细胞发生EMT时,伴随着迁... 详细信息

上皮间质转化(epithelial-mesenchymal transition,EMT)是指上皮细胞表型由上皮向间质转换的生物学过程,可发生在生理过程中促进发育、组织愈合和修复。近年对肿瘤的研究发现,EMT与肿瘤的发生发展密切相关。肿瘤细胞发生EMT时,伴随着迁移、侵袭能力的增强,进而促进肿瘤的转移。EMT发生的程度以及相关标志分子的检测还可以用于判断肿瘤转移的危险和评估预后。MicroRNA(miRNA)作为非编码小RNA,通过与特定mRNA的3'UTR结合,在蛋白翻译水平抑制基因表达。本文主要综述目前发现的作用于EMT相关转录因子,如ZEB、SNAIL、TWIST的miRNA,以及在各种肿瘤中的表达情况和作用。其中,有些转录因子和miRNA之间,还存在相互抑制的复杂调节网络,因此,了解miRNA在肿瘤中对EMT的作用可能为肿瘤的治疗提供新的方法和策略。

关键词：上皮间质转化 MicroRNA 肿瘤

Spatial transcriptomics combined with single-nucleus RNA sequencing reveals glial cell heterogeneity in the human spinal cord

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Neural Regeneration Research 2025年第11期20卷 3302-3316页

作者： Yali chen Yiyong Wei jin Liu Tao Zhu cheng Zhou Donghang Zhang Department of Anesthesiology West China HospitalSichuan UniversityChengduSichuan ProvinceChina Laboratory of Anesthesia and Critical Care Medicine National-Local Joint Engineering Research Center of Translational Medicine of AnesthesiologyWest China HospitalSichuan UniversityChengduSichuan ProvinceChina Department of Anesthesiology Longgang District Maternity&Child Healthcare Hospital of Shenzhen City(Longgang Maternity and Child Institute of Shantou University Medical College)ShenzhenGuangdong ProvinceChina Department of Anesthesiology Affiliated Hospital of Zunyi Medical UniversityZunyiGuizhou ProvinceChina

Glial cells play crucial roles in regulating physiological and pathological functions,including sensation,the response to infection and acute injury,and chronic neurodegenerative *** cells include astrocytes,microglia,and oligodendrocytes in the central nervous system,and satellite glial cells and Schwann cells in the peripheral nervous *** the greater understanding of glial cell types and functional heterogeneity achieved through single-cell and single-nucleus RNA sequencing in animal models,few studies have investigated the transcriptomic profiles of glial cells in the human spinal ***,we used high-throughput single-nucleus RNA sequencing and spatial transcriptomics to map the cellular and molecular heterogeneity of astrocytes,microglia,and oligodendrocytes in the human spinal *** explore the conservation and divergence across species,we compared these findings with those from *** the human spinal cord,astrocytes,microglia,and oligodendrocytes were each divided into six distinct transcriptomic *** the mouse spinal cord,astrocytes,microglia,and oligodendrocytes were divided into five,four,and five distinct transcriptomic subclusters,*** comparative results revealed substantial heterogeneity in all glial cell types between humans and ***,we detected sex differences in gene expression in human spinal cord glial ***,in all astrocyte subtypes,the levels of NEAT1 and CHI3L1 were higher in males than in females,whereas the levels of CST3 were lower in males than in *** all microglial subtypes,all differentially expressed genes were located on the sex *** addition to sex-specific gene differences,the levels of MT-ND4,MT2A,MT-ATP6,MT-CO3,MT-ND2,MT-ND3,and MT-CO_(2) in all spinal cord oligodendrocyte subtypes were higher in females than in ***,the present dataset extensively characterizes glial cell heterogeneity and offers a valuable resource for explo

关键词： astrocyte glial cell human microglia oligodendrocyte sex differentiation single-nucleus RNA sequencing spatial transcriptomics species variation spinal cord