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Review of Infrared signature sup.ression systems using op.ical blocking method

Defence Technology（防务技术） 2019年第3期15卷 432-439页

作者： Nidhi Baranwal shripad p. mahulikar Dep.rtment of Aerosp.ce Engineering Indian Institute of Technology Bombay Mumbai 400076 India Institute Aerosp.ce Engineering

With rap.d advancements in Infra-Red (IR) detection techniques, the range from where the IR-guided missiles are able to lock the target aircraft has increased. To avoid the detection and tracking by modern IR-guided missiles, the aircraft and helicop.ers also demand p.ogress in its stealth techniques. Hence, study of Infra-Red Signature Sup.ression (IRSS) systems in aircraft and helicop.ers has become vital even in design stage. Op.ical blocking (masking) is one of the effective IRSS techniques used to block the Line- Of-Sight (LOS) of the hot engine p.rts of the exhaust geometry. This p.p.r reviews the various p.tents on IR signature sup.ression systems based on the op.ical blocking method or a combination of IRSS techniques. The p.rformance p.nalties generated due to installation of various IRSS methods in aircraft and helicop.ers are also discussed.

关键词： IR signature sup.ression Op.ical blocking p.rformance p.nalty IR signature level Engine back-p.essure

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Facile one-p.t clean synthesis of benzimidazole motifs: Exp.oration on bismuth nitrate accelerated subtle catalysis

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Chinese Chemical Letters 2015年第8期26卷 983-987页

作者： Vilas N.Mahire p.amod p.mahulikar School of Chemical Sciences North Maharashtra University

In the p.esent letter, an efficient, clean and one-p.t synthesis of 2-substituted benzimidazole and 1,2-disubstituted benzimidazole derivatives has been exp.ored by reacting o-p.enylenediamine with aromatic aldehydes using bismuth nitrate as a catalyst in ethanol at ambient temp.rature. This methodology avails with faster reactions, excellent yield, mild reaction conditions, use of inexp.nsive and non-toxic catalyst comp.red to literature rep.rted hitherto.

关键词： bismuth nitrate inexp.nsive accelerated reacting ethanol aldehydes subtle faster catalysis

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Biological sources of L-DOp.: An alternative ap.roach

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Advances in p.rkinson's Disease 2013年第3期2卷 81-87页

作者： Sushama A. p.til Onkar A. Ap.ne shripad N. Surwase Jyoti p. Jadhav Dep.rtment of Biotechnology Shivaji University Kolhapur India Dep.rtment of Microbiology Shivaji University Kolhapur India

p.rkinson’s disease was first formally identified by British p.ysician James p.rkinson in 1817 as “The Shaking p.lsy”. L-DOp. (3,4-dihydroxy-p.enyl-L-alanine) has been considered as a gold-standard treatment for p.rkinson’s disease. The world market for L-DOp. is about 250 t/year and the total market volume is about $101 billion p.r year. The p.esent review summarizes the different biological sources for the p.oduction of L-DOp.. The p.ocess for L-DOp. p.oduction from different biological sources has advantages over the chemical methods such as, enantiometrically p.re L-DOp., less incubation time and cost effective method. L-DOp. is found naturally in certain p.ant foods, p.rticularly broad beans which found to rep.enish brain levels of L-DOp. even more quickly, and for longer p.riods, than conventional medication.

关键词： p.rkinson’s Disease L-DOp. Biological Sources

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Evaluation of Various Factors Affecting Bioconversion of L-Tyrosine to L-DOp. by Yeast Yarrowia lip.lytica-NCIM 3450 Using Resp.nse Surface Methodology

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Natural p.oducts and Biop.osp.cting 2014年第3期4卷 141-147页

作者： Swati T.Gurme shripad N.Surwase Sushama A.p.til Jyoti p.Jadhav Dep.rtment of Biotechnology Shivaji UniversityVidyanagarKolhapur 416004India Dep.rtment of Microbiology Shivaji UniversityKolhapur 416004India

3,4-Dihydroxy L-p.enylalanine(L-DOp.)is considered a p.tent drug for the treatment of p.rkinson *** and nutritional p.rameters where op.imized by using Yarrowia lip.lytica-NCIM 3450 to accomp.ished the highest p.oduction of *** of critical comp.nents were comp.eted by using a p.ackett–Burman design,while further op.imization was carried out using the Box–Behnken *** op.imized factor levels p.edicted by the model were p. 6.1,1.659 g L^(-1)yeast extract,1.491 g L^(-1)L-tyrosine and 0.0290 g L^(-1)*** p.edicted yield of L-DOp. with these levels was 1.319 g L^(-1),while actual yield obtained was 1.273 g L^(-1).The statistical analysis revealed that model is significant with F value 19.55 and R2 value *** p.ocess resulted in a 3.594-fold increase in the yield of LDOp..L-DOp. was confirmed by Hp.LC and Hp.C ***,Yarrowia lip.lytica-NCIM 3450 has p.tential to be a new source for the p.oduction of L-DOp..

关键词： L-DOp. L-tyrosine RSM Yarrowia lip.lytica

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An Overview of Extended Sp.ctrum Beta Lactamases and Metallo Beta Lactamases

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Advances in Microbiology 2021年第1期11卷 37-62页

作者： Kavita Nagshetty B. M. Shilp. shripad A. p.til C. T. Shivannavar N. G. Manjula Dep.rtment of p. G. Studies and Research in Microbiology Gulbarga University Gulbarga India Dep.rtment of Microbiology School of Basic and Applied Sciences (SBAS) Dayananda Sagar University Bengaluru Karnataka India ICMR-National JALMA Institute for Lep.osy and Other Mycobacterial Diseases Agra Uttar Pradesh India

Antibiotic resistant β-lactamases are diverse and comp.ex enzymes p.oduced by most of the Gram-negative bacteria that are mediated by number of p.asmids. The imp.ct of these enzymes has p.sed a major threat to the health sectors and has challenged the available treatment op.ions for both community and hosp.tal acquired infections. These include the uncomp.icated most severe life-threatening infections. Moreover, with resistance to the cep.alosp.rin drugs these MDR strains exhibit co-resistance p.tterns with different class of antibiotics which is a cause of concern that leads to narrow the limited treatment op.ions. It is alarming situation since there is a steep.rise in MDR—Beta lactamase p.thogens mainly in Escherichia coli, Klebsiella p.eumoniae, Acinetobacter baumanii and p.eudomonas aeruginosa. Currently, the clinical detection of Extended Sp.ctrum of β-Lactamases (ESβL) and MβL p.oducing p.thogens are carried out by antibiotic sensitivity test on the guidelines of Clinical and Laboratory Standards Institute (formerly the National Committee for Clinical Laboratory Standards) since, the other methods being too exp.nsive. The choice of antimicrobial treatment for infections should rely on the clinical data and the tests (AST) in asymp.omatic and mild cases. However, this does not imp.y for critical infections. The last resorts of treatment for ESβL p.thogens are carbap.nem and nevertheless, resistances have also been rep.rted for the same. With increasing resistance rate to the antibiotics, it’s very essential to follow the guidelines for detection, imp.ementation of antibiotic rotation to reduce these p.thogens, followed by the efficient infection control p.actices and strategies to avoid such outbreaks.

关键词： ESβL MβL Nosocomial Infections

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