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Insect Science 2022年第5期29卷 1299-1308页

作者： Meryem Behri Haruki Teshima Keisuke Kutsuwada shoko Nakatake Mari H.Ogihara DeMar Taylor Graduate School of Life and Environmental Sciences University of TsukubaTsukubaIbarakiJapan Animal Breeding and Reproduction Research Division Institute of Livestock and Grassland ScienceNational Agriculture and Food Research OrganizationTsukubaIbarakiJapan

Initiation of vitellogenesis by blood feeding is essential for egg maturation in *** derived from the blood meal are utilized by female ticks to synthesize the yolk protein precursor vitellogenin(Vg).Engorged Ornithodoros moubata ticks can synthesize Vg whether mated or virgin,thus *** is an excellent model for studying the relative roles of blood feeding and mating in tick *** of rapamycin into engorged *** resulted in a reduction of ovarian growth and yolk accumulation in the oocytes of mated *** expression in the midgut and fat body and protein concentrations in the hemolymph significantly decreased in mated ticks after injection with rapamycin,indicating that inhibition of the nutrient-sensing target of rapamycin(TOR)pathway disrupts egg maturation at the levels of Vg expression and *** results suggest that the TOR-signaling pathway induces vitellogenesis in response to nutritional stimulation after a blood meal in *** and is functionally independent of the mating-induced pathway.

关键词： Ornithodoros moubata target of rapamycin ticks vitellogenesis vitellogenin

A Series of Soluble Planar Oligorylenes up to Hexarylene

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Chinese Journal of Chemistry 2023年第9期41卷 1023-1027页

作者： Ryuichi Fujita shoko Yoshida Haruka Kano Kyohei Matsuo Hironobu Hayashi Hiroko Yamada Naoki Aratani Division of Materials Science Nara Institute of Science and Technology(NAIST)8916-5 Takayama-choIkoma 630-0192Japan

Preparation of large rylenes often needs the use of solubilizing groups along the rylene backbone,which results in the distortion of the skeleton and thus broadening of the absorption *** this work,we successfully synthesized 2,5,8,16,19,22-hexakis[2,6-bis(tri-fluoromethyl)phenyl]hexarylene(H)by using an oxidative fusion reaction of perylene trimer in 5%*** product is soluble in common organic solvents and could be purified with column ***-crystal X-ray diffraction analysis revealed that the hexarylene core is not disturbed by the substituents very much and is almost *** longest absorption of H exhibits a sharp peak at 831 nm and an on-set at 875 nm in toluene with a small full-width-at-half-maximum(FWHM)of 660 cm^(-1).The molar extinction coefficient is as large as 131,000 M^(-1)cm^(-1).The substituents could not perturb the electronic properties of the hexarylene because aryl groups are perpendicular to the hexarylene core and the carbon atoms at 2,5,16,19-positions have negligible coeffi-cients on its HOMO and LUMO,estimated by theoretical *** a result,the hexarylene having less absorption at the visible light region was stable enough in solution under the LED room light for more than 1 *** strategy gives a useful guideline to establish the near-infrared materials that exhibit stability under ambient conditions.

关键词： Oligorylenes Undistorted skeleton Near infrared absorption Crystal structure Effective conjugation length

日本高等融合教育支持体系建设及启示——以日本筑波大学为例

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现代特殊教育 2024年第10期 28-35页

作者：何橙棋黄金峰陈俞安宫本昌子日本筑波大学人间综合科学学术院日本筑波3058572 日本筑波大学人间系日本筑波3058572

为构建共生社会,以“消除非公平差别对待,提供合理便利”为核心理念,由文部省领导,国家公立大学牵头试点,日本建立了自上而下的多阶段高等融合教育支持体系,涵盖残障大学生日常生活、学业、就业支持等领域。借鉴其经验,中国可根据国情,... 详细信息

为构建共生社会,以“消除非公平差别对待,提供合理便利”为核心理念,由文部省领导,国家公立大学牵头试点,日本建立了自上而下的多阶段高等融合教育支持体系,涵盖残障大学生日常生活、学业、就业支持等领域。借鉴其经验,中国可根据国情,制定具体的高等融合教育政策方针,以各高校学工部为指导中心,加强高校融合教育管理,加快师资培养,建立学生支持队伍,以进一步促进高等融合教育的发展。

关键词：高等教育融合教育残障大学生支持体系

East Asian VLBI Network observations of active galactic nuclei jets:imaging with KaVA+Tianma+Nanshan

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Research in Astronomy and Astrophysics 2021年第8期21卷 220-234页

作者：崔玉竹 Kazuhiro Hada Motoki Kino Bong-Won Sohn Jongho Park Hyun-Wook Ro Satoko Sawada-Satoh Wu Jiang Lang Cui Mareki Honma 沈志强 Fumie Tazaki 安涛 Ilje Cho Guang-Yao Zhao Xiao-Peng Cheng Kotaro Niinuma Kiyoaki Wajima Ying-Kang Zhang Noriyuki Kawaguchi Juan-Carlos Algaba shoko koyama Tomoya Hirota Yoshinori Yonekura Nobuyuki Sakai Bo Xia Yong-Bin Jiang Lin-Feng Yu Wei Gou Ju-Yeon Hwang Yong-Chen Jiang Yun-Xia Sun Dong-Kyu Jung Hyo-Ryoung Kim Jeong-Sook Kim Hideyuki Kobayashi Jee-Won Lee Jeong-Ae Lee Hua Zhang Guang-Hui Li Zhi-Qiang Xu Peng Li Jung-Hwan Oh Se-Jin Oh Chung-Sik Oh Tomoaki Oyama Duk-Gyoo Roh Katsunori-M.Shibata 郭文 Rong-Bing Zhao Wei-Ye Zhong Jin-Qing Wang Wen-Jun Yang 闫浩 Jae-Hwan Yeom Bin Li 李笑飞 Jian-Ping Yuan Jian Dong Zhong Chen Kazunori Akiyama Keiichi Asada Do-Young Byun Yoshiaki Hagiwara Jeffrey Hodgson Tae-Hyun Jung Kee-Tae Kim Sang-Sung Lee Kunwoo Yi Qing-Hui Liu Xiang Liu Ru-Sen Lu Masanori Nakamura Sascha Trippe Na Wang Xue-Zheng Wang 张波 Department of Astronomical Science The Graduate University for Advanced StudiesSOKENDAI2-21-1 OsawaMitakaTokyo 181-8588Japan Mizusawa VLBI Observatory National Astronomical Observatory of Japan2-12 HoshigaokaMizusawaOshuIwate 023-0861Japan Kogakuin University of Technology and Engineering Academic Support Center2665-1 NakanoHachiojiTokyo 192-0015Japan Korea Astronomy and Space Science Institute Yuseong-guDaejeon 34055Korea Department of Astronomy Yonsei University50 Yonsei-roSeodaemun-guSeoul 03722Korea Department of Astronomy and Space Science University of Science and Technology217 Gajeong-roDaejeonKorea Institute of Astronomy and Astrophysics Academia Sinica645 N Aohoku PIHiloHI 96720USA Graduate School of Sciences and Technology for Innovation Yamaguchi UniversityYoshida 1677-1YamaguchiYamaguchi 753-8512Japan Shanghai Astronomical Observatory Chinese Academy of SciencesShanghai 200030China Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830011China Key Laboratory of Radio Astronomy Chinese Academy of SciencesNanjing 210008China Institute of Astronomy The University of Tokyo2-21-1 OsawaMitakaTokyo 181-0015Japan Instituto de Astrofísica de Andalucía-CSIC Glorieta de la Astronomia s/nGranada E-18008Spain Department of Physics Faculty of ScienceUniversity of MalayaKuala Lumpur 50603Malaysia Center for Astronomy Ibaraki University2-1-1 BunkyoMitoIbaraki 310-8512Japan Space Light Laboratory 77Yangjaedae-ro 86 roadGangdong-guSeoulKorea Massachusetts Institute of Technology Haystack Observatory 99 Millstone RoadWestfordMA 01886USA National Radio Astronomy Observatory 520 Edgemont RdCharlottesvilleVA 22903USA Toyo University 5-28-20 HakusanBunkyo-kuTokyo 112-8606Japan Department of Physics and Astronomy Seoul National UniversityGwanak-guSeoul 08826Korea Max Planck Institute for Radio Astronomy Auf dem hiigel 69Bonn 53121Germany SNU Astronomy Research Center Seoul National UniversityGwanak-guSeoul 08826Korea

The East Asian Very Long Baseline Interferometry(VLBI) Network(EAVN) is a rapidly evolving international VLBI array that is currently promoted under joint efforts among China,Japan and *** aims at forming a joint VLBI Network by combining a large number of radio telescopes distributed over East Asian *** the combination of the Korean VLBI Network(KVN) and the VLBI Exploration of Radio Astrometry(VERA) into Ka VA,further expansion with the joint array in East Asia is actively *** we report the first imaging results(at 22 and 43 GHz) of bright radio sources obtained with Ka VA connected to Tianma 65-m and Nanshan 26-m Radio Telescopes in *** test the EAVN imaging performance for different sources,we observed four active galactic nuclei(AGN) having different brightness and *** a result,we confirmed that the Tianma 65-m Radio Telescope(TMRT) significantly enhances the overall array sensitivity,a factor of 4 improvement in baseline sensitivity and 2 in image dynamic range compared to the case of Ka VA *** addition of the Nanshan 26-m Radio Telescope(NSRT) further doubled the east-west angular *** the resulting high-dynamic-range,high-resolution images with EAVN(Ka VA+TMRT+NSRT),various fine-scale structures in our targets,such as the counter-jet in M87,a kink-like morphology of the 3 C 273 jet and the weak emission in other sources are successfully *** demonstrates the powerful capability of EAVN to study AGN jets and to achieve other science goals in *** expansion of EAVN will further enhance the angular resolution,detection sensitivity and frequency coverage of the network.

关键词： galaxies:active galaxies:jets instrumentation:interferometers radio continuum:galaxies

HISTORY AND PRESENT STATE OF TRANSLATIONAL ELECTRO-OPTICAL APPLICATIONS TO MEDICINE

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Journal of Innovative Optical Health Sciences 2008年第1期1卷 1-15页

作者： BRITTON CHANCE shoko NIOKA Department of Biochemistry and Biophysics University of Pennsylvania PA USA Britton Chance Center for Biomedical Photonics Wuhan National Lab for Optoelectronics Huazhong University of Science and Technology WuhanChina

This paper reviews the history of the optoelectric devices applied to biomedical sciences in 20th *** describes history of Vacuum tubes and Spectroscopies with the author’s personal experiences,especially doublebeam ***,the present developments of Near Infra Red(NIR)devices are described in translational biomedical *** includes particulary micro optoelectronics developments and present status of NIR breast cancer ***,intrinsic molecular biomarkers are discussed especially NIR measurements of angiogenensis,hypermetabolism and heat production for cancer detection.

关键词： History vacuum tube double beam spectrometer NIR Biomarker

To Gate, or Not to Gate： Regulatory Mechanisms for Intercellular Protein Transport and Virus Movement in Plants

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Molecular Plant 2011年第5期4卷 782-793页

作者： shoko Ueki Vitaly Citovsky Institute of Plant Science and Resources Okayama University 2-20-1 Chuo Kurashiki Okayama 710-0046 Japan Department of Biochemistry and Cell Biology State University of New York Stony Brook NY 11794-5215 USA

Cell-to-cell signal transduction is vital for orchestrating the whole-body physiology of multi-cellular organ- isms, and many endogenous macromolecules, proteins, and nucleic acids function as such transported signals. In plants, many of these molecules are transported through plasmodesmata （Pd）, the cell wall-spanning channel structures that interconnect plant cells. Furthermore, Pd also act as conduits for cell-to-cell movement of most plant viruses that have evolved to pirate these channels to spread the infection. Pd transport is presumed to be highly selective, and only a limited repertoire of molecules is transported through these channels. Recent studies have begun to unravel mechanisms that actively regulate the opening of the Pd channel to allow traffic. This macromolecular transport between cells comprises two consecutive steps： intracellular targeting to Pd and translocation through the channel to the adjacent cell. Here, we review the current knowledge of molecular species that are transported though Pd and the mechanisms that control this traffic. Generally, Pd traffic can occur by passive diffusion through the trans-Pd cytoplasm or through the membrane/lu- men of the trans-Pd ER, or by active transport that includes protein-protein interactions. It is this latter mode of Pd trans- port that is involved in intercellular traffic of most signal molecules and is regulated by distinct and sometimes interdependent mechanisms, which represent the focus of this article.

关键词： Plasmodesmata cell-to-cell transport plant viruses transcription factors

Exploring the Lives of Mothers Raising Children with Autism Spectrum Disorder in Japan

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Open Journal of Nursing 2023年第2期13卷 167-180页

作者： Azusa Kawakami shoko Mano Yoko Shibuya Department of Nursing Nara Medical University Kashihara Nara Japan Department of Nursing Setsunan University Hirakata Osaka Japan

Background: Examining the lives that mothers experience and build will allow us to deepen our understanding of children with ASD and their mothers and facilitate developing support methods. The study aimed to examine the lives of mothers raising children with autism spectrum disorder (ASD) and investigate their sources of support. Method: We conducted a qualitative inductive study using semi-structured interviews to identify characteristics of the lives that mothers have created. Results: Semi-structured interviews were conducted with 11 mothers having children with ASD. The analysis comprised three stages of coding and yielded eight categories. The lives of these mothers contained three themes: preoccupation with parenting children with ASD and their siblings;evolving mother;and using social resources. Mothers engaged in “assessing the characteristics, growth, and changes in the child with ASD”, had a “preoccupation with parenting children with ASD”, and were “thinking about the future of the child with ASD”, and “having goals and plans for parenting” while having “consideration toward the child’s siblings”. During this process, mothers experienced “changes in perspective or approach” and created lifestyles while “receiving help from people around them” and engaged in the “use of social resources”. Conclusions: To avoid becoming preoccupied with parenting and being burdened by their lifestyle, mothers require social support to monitor their perceptions. Furthermore, the utilization of social resources requires the supporting individuals to understand the characteristics of children with ASD, provide appropriate information, and assist in decision-making.

关键词： Autism Spectrum Disorder Mothers Raising Children

A NOVEL TIME-SHARED FLUOROMETER GIVES THE MITOCHONDRIAL REDOX STATE AS THE RATIO OF TWO COMPONENTS OF THE RESPIRATORY CHAIN OF THE ANIMAL AND HUMAN BUCCAL CAVITY WITH QUANTITATIVE MEASURES OF THE REDOX ENERGY STATE

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Journal of Innovative Optical Health Sciences 2010年第4期3卷 235-245页

作者： BRITTON CHANCE shoko NIOKA AQUO JENQ-RUEY HORNG University of Pennsylvania Philadelphia PA 19104USA South Taiwan University 1 Nantai RoadYong KangTainan 71005Taiwan

The source of energy for life is the tissue mitochondria and they demand a complex chain of biochemicals to ensure proper physiological ***,the blood levels,and not the tissue levels of these metabolites,are determined by expensive and time-consuming biochemical *** the tissue mitochondria are the consumers of the substrates of glycolysis and of fatty acid metabolism,their redox state is a unique accessible monitor of tissue metabolism and its blockade due to toxins.

关键词： Redox state mitochondria optical methods fluorometer

Charge transfer between biogenic jarosite derived Fe^3＋ and TiO2 enhances visible light photocatalytic activity of TiO2

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Journal of Environmental Sciences 2017年第4期29卷 256-267页

作者： Mahabubur Chowdhury Sipiwe shoko Fransciuos Cummings Veruscha Fester Tunde Victor Ojumu Flow Process and Rheolofy Centre Cape Peninsula University of Technology South Africa Department of Chemical Engineering Cape Peninsula University of Technology South Africa Electron Microscope Unit University of the Western Cape South Africa

In this work, we have shown that mining waste derived Fe^3＋can be used to enhance the photocatalytic activity of TiO2. This will allow us to harness a waste product from the mines, and utilize it to enhance TiO2 photocatalytic waste water treatment efficiency. An organic linker mediated route was utilized to create a composite of TiO2 and biogenic jarosite. Evidence of Fe／O／Ti bonding in the TiO2/jarosite composite was apparent from the FTIR, EFTEM, EELS and ELNEFS analysis. The as prepared material showed enhanced photocatalytic activity compared to pristine TiO2, biogenic jarosite and mechanically mixed sample of jarosite and TiO2 under both simulated and natural solar irradiation. The prepared material can reduce the electrical energy consumption by 4 times compared to pristine P25 for degradation of organic pollutant in water. The material also showed good recyclability. Results obtained from sedimentation experiments showed that the larger sized jarosite material provided the surface to TiO2 nanoparticles, which increases the settling rate of the materials. This allowed simple and efficient recovery of the catalyst from the reaction system after completion of photocatalysis. Enhanced photocatalytic activity of the composite material was due to effective charge transfer between TiO2 and jarosite derived Fe^3＋as was shown from the EELS and ELNEFS. Generation of OHU was supported by photoluminesence（PL） experiments.

关键词： Biogenic jarosite TiO2 photocatalysis Charge transfer Organic pollutant Visible light responsive Water treatment

Estrogen and oxytocin involvement in social preference in male mice:a study using a novel long-term social preference paradigm with aromatase,estrogen receptor-αand estrogen receptor-β,oxytocin,and oxytocin receptor knockout male mice

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Integrative Zoology 2018年第6期13卷 698-710页

作者： Mumeko C.TSUDA Kazuyo NAGATA shoko SAGOSHI Sonoko OGAWA Laboratory of Behavioral Neuroendocrinology University of TsukubaTsukubaIbarakiJapan

Certain aspects of social behavior help animals make adaptive decisions during encounters with other *** mice choose to approach another conspecific,the motivation and preference behind the interaction is not well *** and oxytocin are known to influence a wide array of social behaviors,including social motivation and social *** present study investigated the effects of estrogen and oxytocin on social preference using aromatase(ArKO),estrogen receptor(ER)α(αERKO),ERβ(βERKO),oxytocin(OTKO),oxytocin receptor(OTRKO)knockout and their respective wild-type(WT)male *** were presented with gonadally-intact versus castrated male(IC),intact male versus ovariectomized female(IF),or intact male versus empty cage(IE)stimuli sets for 5 *** showed no preference for either stimuli in IC and IF and intact male preference in IE,but ArKO mice preferred a castrated male or an ovariectomized female,or had no preference for either stimulus in IC,IF and IE stimuli sets,respectively,suggesting reduced intact male preference.αandβWT mice preferred a castrated male,showed no preference,and preferred an intact male in IC,IF and IE,respectively.αERKO mice displayed similar modified social preference patterns as ArKO,whereas the social preference ofβERKO mice remained similar toβ*** preferred a castrated male whereas OTKO,OTRWT and OTRKO mice failed to show any preference in IC and none showed preference for either stimuli in ***,these findings suggest that estrogen regulates social preference in male mice and that impaired social preference in oxytocin-deficient mice may be due to severe deficits in social recognition.

关键词： aromatase estrogen receptor oxytocin receptor social motivation social preference