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On-chip 3D rotation of oocyte based on a vibration-induced local whirling flow

Microsystems & Nanoengineering 2015年第1期1卷 150-158页

作者： Takeshi Hayakawa shinya sakuma Fumihito Arai Department of Micro-Nano Systems Engineering Nagoya UniversityNagoya-CityAichi-Pref.JAPAN

We propose a novel on-chip 3D cell rotation method based on a vibration-induced *** circular vibration is applied to a microchip with micropillar patterns,a highly localized whirling flow is induced around the *** direction and velocity of this flow can be controlled by changing the direction and amplitude of the applied ***,this flow can be induced on an open chip *** this study,we adopted a microchip with three micropillars arranged in a triangular configuration and an xyz piezoelectric actuator to apply the circular *** the centre of the micropillars,the interference of the vibration-induced flows originating from the individual micropillars induces rotational ***,a biological cell placed at this centre rotates under the influence of the *** three-plane circular vibrations in the xy,xz or yz plane,the cell can rotate in both the focal and vertical planes of the *** this 3D cell rotation method,we measured the rotational speeds of mouse oocytes in the focal and vertical planes as 63.7±4.0°s^(−1) and 3.5±2.1°s^(−1),***,we demonstrated the transportation and rotation of the mouse oocytes and re-positioned their nuclei into a position observable by microscope.

关键词： lab on a chip cell manipulation vibration-induced flow acoustic streaming

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Design of Electrohydrodynamic Devices with Consideration of Electrostatic Energy

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Cyborg and Bionic Systems 2021年第1期2021卷 32-39页

作者： Tasuku Sato shinya sakuma Masato Hijikuro Shingo Maeda Masayuki Anyoji Yoko Yamanishi Kyushu University 744 MotookaNishi-kuFukuoka 819-0395Japan Kyushu University 6-1 Kasuga KoenKasuga-shiFukuoka 816-8580Japan Shibaura Institute of Technology 3-7-5 ToyosuKoto-kuTokyo 135-8548Japan

The importance of actuators that can be integrated with flexible robot structures and mechanisms has increased in recent years with the advance of soft *** particular,electrohydrodynamic(EHD)actuators,which have expandable integrability to adapt to the flexible motion of soft robots,have received much attention in the field of soft *** have deepened the understanding of steady states of EHD phenomena but nonsteady states are not well *** herein observe the development process of fluid in a microchannel adopting a Schlieren technique with the aid of a high-speed *** addition,we analyze the behavior of fluid flow in a microchannel that is designed to have pairs of parallel plate electrodes adopting a computational fluid dynamics *** indicate the importance of considering flow generated by electrostatic energy,which tends to be ignored in constructing and evaluating EHD devices,and by the body force generated by the ion-drag *** considering these effects,we estimate the development process of EHD flow and confirm the importance of considering the generation of vortices and their interactions inside the microchannel during the development of EHD devices.

关键词： EHD flow electrostatic

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