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Effects of oral probiotics on inflammation and intestinal function in adult patients after appendectomy:Randomized controlled trial

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World Journal of Gastrointestinal Surgery 2024年第5期16卷 1371-1376页

作者： Ke Lan Ke-Rui Zeng Fu-Rui Zhong Sheng-Jin Tu Jin-long Luo shi-long shu Xue-Feng Peng Hua Yang Kai Lu Department of General Surgery Zigong Fourth People's HospitalZigong 643000Sichuan ProvinceChina

BACKGROUND Appendectomy is an acute abdominal surgery that is often accompanied by severe abdominal *** probiotics are one of the postoperative treatments for rapid ***,there is a lack of prospective studies on this topic after *** To investigate whether the postoperative probiotics can modulate the inflammatory response and restore intestinal function in patients following *** This was a prospective,randomized trial.A total of 60 emergency patients were randomly divided into a control group(n=30)and a probiotic group(n=30).Patients in the control group started to drink some water the first day after surgery,and those in the probiotic group were given water supplemented with Bacillus licheniformis capsules for 5 consecutive days *** indices of inflammation and postoperative conditions were recorded,and the data were analyzed with RStudio 4.3.2 *** A total of 60 participants were *** with those in the control group,the C-reactive protein(CRP),interleukin 6 and procalcitonin(PCT)levels were significantly lower in the probiotic group at 2 d after surgery(P=2.224e-05,P=0.037,and P=0.002,respectively,all P<0.05).This trend persisted at day 5 post-surgery,with CRP and PCT levels remaining significantly lower in the probiotic group(P=0.001 and P=0.043,both P<0.05).Furthermore,probiotics0.028,both P<0.05).CONCLUSION Postoperative oral administration of probiotics may modulate the gut microbiota,benefit the recovery of the early inflammatory response,and subsequently enhance recovery after appendectomy.

关键词： Probiotics Gut microbiota Appendectomy Inflammatory markers Intestinal function Enhanced recovery after surgery Postsurgical infections

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Concise extraction and characterization of the pore-throat network in unconventional hydrocarbon reservoirs: A new perspective

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Petroleum Science 2024年第3期21卷 1474-1487页

作者： shu-Heng Du Yong-Min shi State Key Laboratory of Nonlinear Mechanics Institute of MechanicsChinese Academy of SciencesBeijing100190China School of Engineering Science University of Chinese Academy of SciencesBeijing100049China School of Earth and Space Sciences Peking UniversityBeijing100871China

In this study,a new image-based method for the extraction and characterization of pore-throat network for unconventional hydrocarbon storage and exploitation is proposed.“Pore-throat solidity”,which is analogous to particle solidity,and a new method for automatic identification of pores and throats in tight sandstone oil reservoirs are ***,the“pore-throat combination”and“pure pore”are defined and distinguished by drawing the cumulative probability curve of the pore-throat solidity and by selecting an appropriate cutoff *** the discrete grid set is recognized as a pore-throat combination,Legendre ellipse fitting and minimum Feret diameter are *** the pore and throat grid sets are identified as pure pores,the pore diameter can be directly *** the new method,the analytical results for the physical parameters and pore radius agree well with most prior *** results comparing the maximum ball and the new model could also prove the accuracy of the latter's in micro and nano *** new model provides a more practical theoretical basis and a new calculation method for the rapid and accurate evaluation of the complex processes of oil migration.

关键词： Hydrocarbon exploitation Pore Throat Porous media Identification

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Metallurgy and Solidification Microstructure Control of Fusion-Based Additive Manufacturing Fabricated Metallic Alloys:A Review

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Acta Metallurgica Sinica(English Letters) 2024年第1期37卷 29-53页

作者： Qiang Li Xing-Ran Li Bai-Xin Dong Xiao-long Zhang shi-Li shu Feng Qiu Lai-Chang Zhang Zhi-Hui Zhang Key Laboratory of Bionic Engineering(Ministry of Education) and College of Bionic Science and EngineeringJilin UniversityChangchun130022China Institute of Structured and Architected Materials Liaoning Academy of MaterialsShenyang110167China Key Laboratory of Automobile Materials Ministry of Education and Department of Materials Science and EngineeringJilin UniversityChangchun130025China School of Mechanical and Aerospace Engineering Jilin UniversityChangchun130025China School of Engineering Edith Cowan University270 Joondalup DriveJoondalupPerthWA6027Australia

The metal-based additive manufacturing(AM),also referred to as metal 3D printing,has drawn particular interest because it enables direct creation,aided by computationally-directed path design,of intricate components with site-specific compositions and geometrical requirements as well as low buy-to-fly *** the last two decades,the objective of this revolutionary technology has been shifting from only“rapid prototyping”to advanced manufacturing of special high-end products or devices,which,in many aspects,outperform conventional manufacturing *** fusion-based AM,significant progress has been achieved in understanding the processing window of macroscopic scales,non-equilibrium metallurgy of mesoscale scales,and grain evolution of microscopic *** the versatile capacity of AM facilitates new avenues for discovering advanced materials and structures,their potential has still not been fully *** the unique non-equilibrium solidification during the AM process,coarse columnar grains with strong textures are usually developed along the build direction,which downgrades the mechanical *** push the limits of this digital manufacturing,this review attempts to provide in-depth and comprehensive overviews of the recent progress in understanding the evolution and control of the as-built microstructure that has been made recently and the challenges encountered during the AM process.

关键词： Additive manufacturing Temperature field Microstructure control Nanoparticles Functionally graded materials

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GNSS gyroscopes:determination of angular velocity and acceleration with very high-rate GNSS

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Satellite Navigation 2024年第1期5卷 74-90页

作者： Yun shi Peiliang Xu Yuanming shu Xiaolin Meng School of Geomatics Xi’an University of Science and TechnologyXi’an710054People’s Republic of China Disaster Prevention Research Institute Kyoto UniversityUjiKyoto611-0011Japan College of Marine Geosciences Ocean University of ChinaQingdaoPeople’s Republic of China School of Instrument Science and Engineering Southeast UniversityNanjing210096People’s Republic of China

Although global navigation satellite systems(GNSS)have been routinely applied to determine attitudes,there exists no literature on determining angular velocity and/or angular acceleration from *** by the invention of computerized accelerometers of the correspondence author and following the success of accurately recovering translational velocity and acceleration waveforms from very high-rate GNSS precise positioning by Xu and his collaborators in 2021,we propose the concept of GNSS gyroscopes and reconstruct angular velocity and acceleration from very high-rate GNSS attitudes by applying regularization under the criterion of minimum mean squared *** major results from the experiments can be summarized in the following:(i)angular velocity and acceleration waveforms computed by applying the difference methods to high-rate GNSS attitudes are too noisy and can be physically not meaningful and numerically *** same can be said about inertial measurement unit(IMU)attitudes,if IMU gyros are not of very high accuracy;(ii)regularization is successfully applied to reconstruct the high-rate angular velocity and acceleration waveforms from 50 Hz GNSS attitudes and significantly outperforms the difference methods,validating the proposed concept of GNSS *** comparing the angular velocity and acceleration results by using the difference methods and regularization,we find that the peak values of angular velocity and acceleration by regularization are much smaller by a maximum factor of 1.57 in the angular velocity to a maximum factor of 8662.53 times in the angular acceleration in the case of high-rate GNSS,and by a maximum factor of 1.26 in the angular velocity to a maximum factor of 2819.85 times in the angular acceleration in the case of IMU,respectively;and(iii)the IMU attitudes apparently lead to better regularized angular velocity and acceleration waveforms than the high-rate GNSS attitudes,which can well be explained by the fact that the

关键词： Angular velocity Angular acceleration High-rate GNSS GNSS attitudes GNSS gyroscopes Regularization

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Quantitative effect of kerogen type on the hydrocarbon generation potential of Paleogene lacustrine source rocks,Liaohe Western Depression,China

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Petroleum Science 2024年第1期21卷 14-30页

作者： Sha-Sha Hui Xiong-Qi Pang Fu-Jie Jiang Chen-Xi Wang shu-Xing Mei Tao Hu Hong Pang Min Li Xiao-long Zhou Kan-Yuan shi State Key Laboratory of Petroleum Resources and Prospecting China University of Petroleum(Beijing)Beijing102249China College of Geosciences China University of Petroleum(Beijing)Beijing102249China Exploration and Development Research Institute PetroChina Liaohe Oilfield CompanyPanjin 124010LiaoningChina

Kerogen types exert a decisive effect on the onset and capacity of hydrocarbon generation of source *** source rocks in the Liaohe Western Depression are characterized by thick deposition,high total organic carbon(TOC)content,various kerogen types,and a wide range of thermal ***,their hydrocarbon generation potential and resource estimation can be *** this study,geochemical tests,numerical analysis,hydrocarbon generation kinetics,and basin modeling were integrated to investigate the differential effects of kerogen types on the hydrocarbon generation potential of lacustrine source *** hydrocarbon generation and expulsion(HGE)models of different kerogen types were established quantitatively upon abundant Rock-Eval/TOC/vitrinite reflectance(R_(o))*** sets of good-excellent source rocks deposited in the fourth(Es4),third(Es3),and first(Es1)members of Paleogene Shahejie Formation,are predominantly types I-II_(1),II_(1)-II_(2),and II-III,*** activation energy of types I-II_(2)kerogen is concentrated(180-230 kcal/mol),whereas that of type III kerogen is widely distributed(150-280 kcal/mol).The original hydrocarbon generation potentials of types I,II_(1),II_(2),and III kerogens are 790,510,270,and 85 mg/g TOC,*** Ro values of the hydrocarbon generation threshold for type I-III source rocks gradually increase from 0.42%to 0.74%,and Ro values of the hydrocarbon expulsion threshold increase from 0.49%to 0.87%.Types I and II_(1)source rocks are characterized by earlier hydrocarbon generation,more rapid hydrocarbon expulsion,and narrower hydrocarbon generation windows than types II_(2)and III source *** kerogen types also affect the HGE history and resource *** types(conventional,tight,and shale oil/gas)and three levels(realistic,expected,and prospective)of hydrocarbon resources of different members in the Liaohe Western Depression are *** suggest that t

关键词： Kerogen type Hydrocarbon generation potential Lacustrine source rocks Liaohe western depression

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Asymptotic normality of error density estimator in stationary and explosive autoregressive models

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Applied Mathematics(A Journal of Chinese Universities) 2024年第1期39卷 140-158页

作者： WU shi-peng YANG Wen-zhi GAO Min HU shu-he School of Mathematical Sciences&School of Big Data and Statistics Anhui UniversityHefei 230601China School of Statistics Shanxi University of Finance and EconomicsTaiyuan030006China

In this paper,we consider the limit distribution of the error density function estima-tor in the rst-order autoregressive models with negatively associated and positively associated random *** mild regularity assumptions,some asymptotic normality results of the residual density estimator are obtained when the autoregressive models are stationary process and explosive *** order to illustrate these results,some simulations such as con dence intervals and mean integrated square errors are provided in this *** shows that the residual density estimator can replace the density\estimator"which contains errors.

关键词： explosive autoregressive models residual density estimator asymptotic distribution association sequence

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Effect of multiple coulomb scattering on the beam tests of silicon pixel detectors

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Nuclear Science and Techniques 2024年第4期35卷 200-207页

作者： Lan-Kun Li Ming-Yi Dong Ze Gao Liang-Cheng-long Jin shu-Jun Zhao School of Physics and Microelectronics Zhengzhou UniversityZhengzhou 450001China State Key Laboratory of Particle Detection and Electronics(Institute of High Energy Physics CAS)Beijing 100049China University of Chinese Academy of Science Beijing 100049China University of South China Hengyang 421001China

In the research and development of new silicon pixel detectors,a collimated monoenergetic charged-particle test beam equipped with a high-resolution pixel-beam telescope is crucial for prototype verification and performance *** the beam energy is low,the effect of multiple Coulomb scattering on the measured resolution of the Device Under Test(DUT)must be considered to accurately evaluate the performance of the pixel chips and *** study aimed to investigate the effect of multiple Coulomb scattering on the measured resolution,particularly at low beam *** were conducted using Allpix^(2) to study the effects of multiple Coulomb scattering under different beam energies,material budgets,and telescope *** simulations also provided the minimum energy at which the effect of multiple Coulomb scattering could be *** with the results of a five-layer detector system tested with an electron beam at DESY,the simulation results were consistent with the beam test results,confirming the reliability of the simulations.

关键词： Silicon Pixel Detectors Beam Telescope Multiple Coulomb Scattering Spatial Resolution

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Anti-aging performance improvement and enhanced combustion efficiency of boron via the coating of PDA

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Defence Technology（防务技术） 2024年第3期33卷 399-410页

作者： shuai Ma Qinghai shu Mengyang Zhang Hongyu Huang Yansong shi Xijuan Lv shuai Zhao School of Materials Science and Engineering Beijing Institute of TechnologyBeijing100081China Key Lab of Advanced Optoelectronic Quantum Architecture and Measurement(MOE) Beijing Key Lab of Nanophotonics&Ultrafine Optoelectronic SystemsSchool of PhysicsBeijing Institute of TechnologyBeijing100081China Tangshan Research Institute of Beijing Institute of Technology Tangshan063000HebeiChina

Boron is an ambitious fuel in energetic materials since its high heat release values,but its application is prohibited by low combustion efficiency and oxidization during *** polydopamine(PDA)was introduced into boron particles,investigating the impact of PDA content on the energetic behavior of *** results indicated that the PDA coating formed a fishing net structure on the surface of boron *** heat release results showed that the combustion calorific value of B@PDA was higher than that of the raw ***,the actual combustion heat of boron powder in B@10%PDA increased by 38.08%.Meanwhile,the DSC peak temperature decreased by 100.65℃under similar oxidation rate compared to raw ***,the B@PDA@AP and B@AP composites were prepared,and their combustion properties were *** was demonstrated that B@10%PDA@AP exhibited superior performance in terms of peak pressure and burning time,*** peak pressure is 12.43 kPa more than B@AP and burning time is 2.22 times higher than B@***,the coating of PDA effectively inhibits the oxidization of boron during storage and enhances the energetic behavior of boron and corresponding composites.

关键词： Boron particles Polydopamine Anti-aging performance improvement Heat release

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Joint Transmit and Reflective Beamforming Design for Active IRS-Aided SWIPT Systems

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Chinese Journal of Electronics 2024年第2期33卷 536-548页

作者： Weiping shi Qingqing WU Di WU Feng shu Jiangzhou WANG School of Electronic and Optical Engineering Nanjing University of Science and Technology Department of Electronic Engineering Shanghai Jiao Tong University School of Information and Communication Engineering Hainan University Department of Automation Shanghai Jiao Tong University School of Engineering University of Kent

To further improve the performance of passive intelligent reflecting surface(IRS)-assisted communication systems and mitigate the serious path loss due to “double-fading ” of IRS-assisted links, an active IRS-aided simultaneous wireless information and power transfer(SWIPT) system is investigated. This paper jointly optimizes the transmit beamforming at the base station(BS) and the phase shifts at the active IRS in order to maximize the power collected by the energy harvesting receiver under both perfect and imperfect channel state information(CSI)states, subject to the signal-to-interference-noise ratio constraint of the information decoding receiver, and the power constraints of the BS/IRS. Under perfect CSI, the alternating optimization algorithm is utilized for obtaining the transmit beamforming at the BS and the phase shifts at the active IRS. For each subproblem, we first transform nonconvex objective function and constraints into convex ones by performing a first-order Taylor expansion. Then, each subproblem is solved by using the interior point method. Given that obtaining perfect CSI is impractical, two robust beamforming designs are proposed for imperfect CSI case. Under the bounded CSI error model, we first transform the non-convex optimization problem into two semidefinite programming subproblems, and then solve each subproblem based on S-procedure and sequential rank-one constraint relaxation(SROCR) techniques. Under the stochastic CSI error model, the alternating optimization method is applied in an iterative manner based on Bernstein-type inequality and SROCR technique. Simulation results show that both robust and non-robust schemes for active IRS-assisted SWIPT systems can achieve extremely superior performance over conventional passive IRS-assisted systems under the same overall power budget.

关键词： Wireless communication Semidefinite programming Array signal processing Simulation Stochastic processes Transforms Receivers

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Electroacupuncture Promotes Angiogenesis in Mice with Cerebral Ischemia by Inhibiting miR-7

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Chinese Journal of Integrative Medicine 2024年第6期30卷 543-550页

作者： YU Qian shu shi JU Xin-yao PENG Wei REN Xue-qi SI shu-han SONG shi-zhen XIE Xue-yun FANG Bang-jiang ZHOU shuang School of Acupuncture-Moxibustion and Tuina Shanghai University of Traditional Chinese MedicineShanghai201203China College of Basic Medicine Shanghai University of Traditional Chinese MedicineShanghai201203China Department of Emergency Longhua HospitalShanghai University of Traditional Chinese MedicineShanghai200032China

Objective To observe the angiogenesis effect of electroacupuncture(EA)at shuigou acupoint(GV 26)in the treatment of cerebral ischemia,and explore the value of miRNA-7(miR-7)in *** First,48 mice were randomly divided into sham operation,middle cerebral artery occlusion(MCAO)model,and EA treatment *** 9 mice were divided into carrier control group,miR-7 knockout group and miR-7 overexpression group(n=3 each group).Finally,20 mice were divided into model and carrier control group,model and miR-7 knockout group,EA treatment and carrier control group and EA treatment and miR-7 overexpression group,with 3–6 mice in each *** MCAO model was established in the MCAO and EA *** deficit score and 2,3,5-triphenyltetrazolium chloride(TTC)staining were used to evaluate the severity of cerebral ***-eosin staining was used to describe basic pathological *** was used to quantify cerebral microvessel ***-time PCR and Western blot were used to detect the expression of miR-7 and its downstream target genes Krüppel-like factor 4/vascular endothelial growth factor(KLF4/VEGF)and angiopoietin-2(ANG-2)in the ischemic cerebral *** After EA,neurological deficit scores and infarction volumes decreased,and the density of cerebral microvessels *** the MCAO group,miR-7 expression was higher than that in the sham group(P<0.01).After EA at GV 26,miR-7 expression decreased(P<0.01)and the expression of downstream target genes KLF4/VEGF and ANG-2 increased as compared with the MCAO group(P<0.01).After EA combined with overexpression of miR-7,the expression of downstream target genes KLF4/VEGF and ANG-2 decreased compared to the control EA group(P<0.01).After miR-7 knockdown,the expression of KLF4/VEGF and ANG-2 increased(P<0.05 or P<0.01).Conclusions EA could promote angiogenesis in MCAO mice likely by inhibiting the expression of miR-7 and relieving inhibition of downstream target genes KLF4/VEG

关键词： electroacupuncture cerebral ischemia miRNA-7 angiogenesis shuigou(GV 26) acupuncture points

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