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Efficacy of acupuncture in refractory irritable bowel syndrome patients: a randomized controlled trial

FRONTIERS OF MEDICINE 2024年第4期18卷 678-689页

作者： Zhao, Jun Zheng, Hui Wang, Xin Wang, Xuefei shi, yunzhou Xie, Chaorong Tao, Qingfeng Li, Da Sun, Jingwen Tian, Junjian Gao, Junxia Liu, Huimin shi, Suhua Ni, Jinxia Xue, Rongdan Hu, Hui Chen, Min Yu, Shuguang Li, Zhigang Beijing Univ Chinese Med Sch Acupuncture Moxibust & Tuina Beijing 100029 Peoples R China Sichuan Univ West China Hosp Dept Integrated Tradit & Western Med Chengdu Peoples R China Chengdu Univ Tradit Chinese Med Hosp 3 Acupuncture & Tuina Sch Chengdu 610000 Peoples R China Capital Med Univ Beijing Hosp Tradit Chinese Med Beijing 100010 Peoples R China Beijing Univ Chinese Med Dept Acupuncture & Moxibust Dongzhimen Hosp Beijing 100700 Peoples R China Beijing Univ Chinese Med Affiliated Hosp 3 Dept Rehabil Beijing 100029 Peoples R China Beijing Univ Chinese Med Dongfang Hosp Dept Acupuncture & Moxibust Beijing 100078 Peoples R China Hosp Chengdu Univ Tradit Chinese Med Anorectal Dis Dept Chengdu 610075 Peoples R China

Previous studies have confirmed that acupuncture for irritable bowel syndrome (IBS) provided an additional benefit over usual care alone. Therefore, we performed a multicenter, randomized, sham-controlled trial to assess the efficacy and safety of acupuncture versus sham acupuncture for refractory IBS in patients in the context of conventional treatments. Patients in the acupuncture and sham acupuncture groups received real or sham acupuncture treatment in 3 sessions per week for a total of 12 sessions. The primary outcome was a change in the IBS-Symptom Severity Scale (IBS-SSS) score from baseline to week 4. A total of 521 participants were screened, and 170 patients (85 patients per group) were enrolled and included in the intention-to-treat analysis. Baseline characteristics were comparable across the two groups. From baseline to 4 weeks, the IBS-SSS total score decreased by 140.0 (95% CI: 126.0 to 153.9) in the acupuncture group and 64.4 (95% CI: 50.4 to 78.3) in the sham acupuncture group. The between-group difference was 75.6 (95% CI: 55.8 to 95.4). Acupuncture efficacy was maintained during the 4-week follow-up period. There were no serious adverse events. In conclusion, acupuncture provided benefits when combined with treatment as usual, providing more options for the treatment of refractory IBS.

关键词： acupuncture functional gastrointestinal disorders irritable bowel syndrome clinical trial

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Mechanical properties of carbon fiber/cellulose composite papers modified by hot-melting fibers

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Progress in Natural Science:Materials International 2014年第1期24卷 56-60页

作者： yunzhou shi Biao Wang State Key Laboratory for Modification of Chemical Fibers and Polymer Materials Donghua University

Carbon fiber(CF)/cellulose(CLS) composite papers were prepared by papermaking techniques and hot-melting fibers were used for modification. The mechanical properties of the obtained composite papers with different CF,CLS and hot-melting fiber ratios were studied and further discussed. It is observed that,for both CF/CLS composite papers and those modified by hot-melting fibers,the normal stress firstly increases and then declines with the addition of carbon fibers. The results also show that with the addition of hot-melting fibers,the modified papers exhibit enhanced mechanical performance compared to CF/CLS composite papers. Through SEM characterization,it is confirmed that the improvement of mechanical properties attributes to the reinforcement of adhesive binding at the fiber overlap nodes. Also,through four-probe method,the resistivity and the electrical performance of the modified and unmodified papers were characterized and the result shows that the hot-melting fiber modification brings no harm to the electrical properties.

关键词： Carbon fibers Composite papers Cellulose fibers Mechanical properties Modification

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Research fronts of agriculture in 2023

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Frontiers of Agricultural Science and Engineering 2024年第2期11卷 347-354页

作者： Jianxiang XU yunzhou LI Jie ZHAO Liang shi Yinkun YAO Jingyue TANG Science and Technology Journal Center Higher Education PressBeijing 100029China FASE Editorial Office of Institute for Science and Technology Development China Agricultural UniversityBeijing 100193China

At the end of 2023, Chinese Academy of Sciences(CAS) and Chinese Academy of Engineering(CAE) successively announced “2023 Research Fronts”^[1] and “2023 Engineering Fronts”^([2,3]), respectively. Among them, agric... 详细信息

关键词： occupy successively agriculture

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非甾体抗炎药致胃溃疡动物模型概述

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中国实验动物学报 2024年第8期32卷 1084-1092页

作者：王雯侯雨君石云舟王路郑倩华周思远陈颖孙路强陈帅鄢香芸李艳秋李瑛成都中医药大学针灸推拿学院成都610075

胃溃疡是一种常见的消化系统疾病,长期服用非甾体抗炎药(non-steroidal anti-inflammatory drugs,NSAIDs)是致病的第二大重要原因。NSAIDs致胃溃疡动物模型是研究NSAIDs致胃肠道损伤发病机制、对应治疗方法和起效机制的有效载体,亦是实... 详细信息

胃溃疡是一种常见的消化系统疾病,长期服用非甾体抗炎药(non-steroidal anti-inflammatory drugs,NSAIDs)是致病的第二大重要原因。NSAIDs致胃溃疡动物模型是研究NSAIDs致胃肠道损伤发病机制、对应治疗方法和起效机制的有效载体,亦是实验的关键,而目前缺乏对NSAIDs致胃溃疡动物模型相关文献的整理与总结。本文就近10年来吲哚美辛和阿司匹林致胃溃疡动物研究相关文献进行整理,从实验动物选择、药物溶剂选择、具体造模方法等方面总结和对比分析,指出当前模型存在的问题:造模方式冗杂、造模细节不够完善、模型不够贴合于临床、药物之间缺乏对比研究等,提出可行的解决思路,以期为此领域的研究提供有效参考。

关键词：非甾体抗炎药吲哚美辛阿司匹林胃溃疡动物模型

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Common traditional Chinese medicine therapies for diarrhea-predominant irritable bowel syndrome: An overview of systematic reviews

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Journal of Traditional Chinese Medical Sciences 2022年第3期9卷 330-339页

作者： Jun Zhao Xia Li Xiaowei Chen Hui Zheng Kun Ye yunzhou shi Xin Xie Jianfang Wang Min Chen Zhigang Li School of Acupuncture Moxibustion and TuinaBeijing University of Chinese MedicineBeijing102488China Department of Spleen StomachLiver and Gallbladder DiseasesDongfang Hospital Affiliated to Beijing University of Chinese MedicineBeijing100078China The Third Hospital/Acupuncture and Tuina School Chengdu University of Traditional Chinese MedicineChengdu610075China Anorectal Disease Department Hospital of Chengdu University of Traditional Chinese MedicineChengdu610072China

Objective: To critically evaluate and summarize the methodological quality of systematic reviews(SRs)and present objective and important outcomes on the effectiveness of traditional Chinese medicine(TCM) therapies, including Chinese herbal medicine(CHM), acupuncture, and moxibustion, for diarrheapredominant irritable bowel syndrome(IBS-D).Methods: We conducted a comprehensive literature search for SRs in 7 databases until April 16, *** reviewers independently extracted data and assessed the methodological quality of the reviews according to the Assessing the Methodological Quality of Systematic Reviews 2(AMSTAR-2), the Risk of Bias in Systematic reviews(ROBIS) tool, and the Preferred Reporting Item for Systematic Review and Meta-analysis(PRISMA) statement. The Grading of Recommendations, Assessment, Development, and Evaluation(GRADE) was used to rate the quality of ***: IBS-D patients included in 12 reviews were diagnosed in accordance with the Rome criteria, 9 reviews focused on CHM, 2 articles observed moxibustion and heat-sensitive moxibustion, 1 article studied acupuncture and CHM. The outcomes of the SRs were the effectiveness rate, the total effectiveness rate,global symptom improvement, and adverse effects. Based on AMSTAR-2, which measures the quality of methodology, all of the included studies were of low or critically low quality. According to the ROBIS tool, 10 SRs(83.33%) had a high risk of bias. With the PRISMA checklist, only 3 SRs reached over 90% *** on GRADE, most evidence was of low quality, and there was a moderate quality of evidence that the effectiveness rate of modified-Tongxie Yaofang was superior to Western medicine in the treatment of ***: Given the suboptimal reporting and methodological quality of existing SRs, more studies are needed to clarify whether TCM therapies are more effective or safe than pharmacological *** studies should combine evidence-based medicine with TCM research a

关键词： Diarrhea-predominant irritable bowel syndrome Overview Traditional Chinese medicine therapies AMSTAR-2 GRADE PRISMA ROBIS

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A nonlinear wake model of a wind turbine considering the yaw wake steering

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Journal of Oceanology and Limnology 2024年第3期42卷 715-727页

作者： yunzhou LI Zhiteng GAO Shoutu LI Suiping QI Xiaoyu TANG College of Meteorology and Oceanography National University of Defense TechnologyChangsha 410073China Multi-function Towing Tank School of Naval ArchitectureOcean and Civil EngineeringShanghai Jiao Tong UniversityShanghai 200240China School of Energy and Power Engineering Lanzhou University of TechnologyLanzhou 730050China Institute of Oceanographic Instrumentation Qilu University of Technology(Shandong Academy of Sciences)Qingdao 266061China State Key Laboratory of Industrial Control Technology College of Control Science and EngineeringZhejiang UniversityHangzhou 310027China Laoshan Laboratory Qingdao 266237China

Duo to fluctuations in atmospheric turbulence and yaw control strategies,wind turbines are often in a yaw *** predict the far wake velocity field of wind turbines quickly and accurately,a wake velocity model was derived based on the method of momentum conservation considering the wake steering of the wind turbine under yaw *** consider the shear effect of the vertical incoming wind direction,a two-dimensional Gaussian distribution function was introduced to model the velocity loss at different axial positions in the far wake region based on the assumption of nonlinear wake *** work also developed a“prediction-correction”method to solve the wake velocity field,and the accuracy of the model results was verified in wake experiments on the Garrad Hassan wind ***,a 33-kW two-blade horizontal axis wind turbine was simulated using this method,and the results were compared with the classical wake model under the same parameters and the computational fluid dynamics(CFD)simulation *** results show that the nonlinear wake model well reflected the influence of incoming flow shear and yaw wake steering in the wake velocity ***,computation of the wake flow for the Horns Rev offshore wind farm with 80 wind turbines showed an error within 8%compared to the experimental *** established wake model is less computationally intensive than other methods,has a faster calculation speed,and can be used for engineering calculations of the wake velocity in the far wakefield of wind turbines.

关键词： far wake wake model wake steering wind shear wind farm

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Initial precursor reaction mechanism of CVD-HfC coating based on density functional theory

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Chinese Journal of Aeronautics 2024年第7期37卷 511-521页

作者： yunzhou LIN Yulei ZHANG Yanqin FU Jian ZHANG Jing’an KONG Ruicong CHEN State Key Laboratory of Solidification Processing Carbon/Carbon Composites Research CenterNorthwestern Polytechnical UniversityXi’an 710072China Henan Key Laboratory of High Performance Carbon Fiber Reinforced Composites Carbon Matrix Composites Research InstituteHenan Academy of SciencesZhengzhou 450046China

Recently,the preparation of ultra-high temperature HfC ceramic coating has gained significant attention,particularly through the application of the HfCl_(4)-CH_(4)-H_(2)-Ar system via Chemical Vapor Deposition(CVD),which has been found widely applied to C/C ***,an analysis of the reactions that occur in the initial stage of the CVD-HfC coating process is presented using Density Functional Theory(DFT)and Transition State Theory(TST)at the B3LYP/Lanl2DZ *** results reveal that HfCl4 can only cleave to produce hypochlorite,which will further react with methyl to synthesize intermediates to form *** to the analysis of the energy barrier and reaction constant,HfCl preferentially reacts with methyl groups to form complex adsorptive intermediates at 1573 *** a C—Hf bond production energy of 212.8 kcal/mol(1 kcal=4.18 kJ),the reaction rate constant of HfCl+CH is calculated to be 2.15×10^(-18) cm^(3)/s at 1573 ***,both the simulation and experimental results exhibit that the upward trend of reaction rate constants with temperature is also consistent with the deposition rate,indicating that the growth curve of the reaction rate constants tends to flatten *** proposed reaction model of the precursor’s decomposition and reconstruction during deposition process has significant implication for the process guidance.

关键词： Carbon composite HfC coating Chemical vapor deposition Density functional theory Precursor reaction mechanism

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互联网平台的犯罪风险防控责任

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中国特色社会主义研究 2023年第4期 61-71页

作者：张旭史云舟吉林大学法学院

《反电信网络诈骗法》的颁布与实施为以互联网平台为代表的互联网服务提供者设置了风险防控这一犯罪预防性责任。犯罪风险防控责任来源于互联网平台在网络治理领域所承担的主体责任,并以风险防控作为责任的价值目标。根据《反电信网络... 详细信息

《反电信网络诈骗法》的颁布与实施为以互联网平台为代表的互联网服务提供者设置了风险防控这一犯罪预防性责任。犯罪风险防控责任来源于互联网平台在网络治理领域所承担的主体责任,并以风险防控作为责任的价值目标。根据《反电信网络诈骗法》的条文规定,犯罪风险防控责任由信息核检义务、特定行为禁止义务、合理注意义务以及侦查协助义务四项基本义务构成。犯罪风险防控责任需通过确立政府监督者地位、提高义务履行标准、限定责任承载范围以及完善既有评价机制的方式在电信网络诈骗犯罪治理领域予以落实。

关键词：《反电信网络诈骗法》风险防控责任犯罪预防义务互联网平台

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针刺对慢性自发性荨麻疹患者应急使用抗组胺药的影响:基于随机对照试验结果的二次分析

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成都中医药大学学报 2024年第5期47卷 19-24页

作者：肖显俊石云舟曹炜邹子豪陈思珏杨茜罗亚兰戴雪纯李瑛金荣疆李涓成都中医药大学四川成都610075

目的:本研究通过对前期多中心随机对照试验数据进行二次分析,评估针刺作为非药物疗法在减少慢性自发性荨麻疹(Chronic Spontaneous Urticaria,CSU)患者对应急使用抗组胺药依赖方面的潜力,为CSU的多元化管理提供新的证据。方法:患者随机... 详细信息

目的:本研究通过对前期多中心随机对照试验数据进行二次分析,评估针刺作为非药物疗法在减少慢性自发性荨麻疹(Chronic Spontaneous Urticaria,CSU)患者对应急使用抗组胺药依赖方面的潜力,为CSU的多元化管理提供新的证据。方法:患者随机分配到针刺组、假针刺组和等待治疗组,并记录了4周治疗期及4周随访期内应急使用抗组胺药的情况。本研究主要评估指标为应急使用抗组胺药的平均天数,通过单因素方差分析(ANOVA)及Tukey HSD多重比较探讨不同时期组间应急使用抗组胺药的平均天数差异。对于组内比较,采用Welch的t检验评估不同时期的差异。非参数Mann-Whitney-U检验进一步验证了组间差异的稳健性。卡方检验和Fisher精确检验用于分析治疗组间用药人数的统计学差异。结果:共分析了296名患者的数据。与针刺组相比,等待治疗组在治疗期(0.30,95%CI0.08 to 0.53,P=0.005)和随访期(0.31,95%CI0.12 to 0.50,P0.05)。此外,与等待治疗组相比,治疗和随访期间接受针刺治疗的患者中应急用药的人数较少(P<0.05)。结论:针刺治疗显示了减轻CSU患者依赖应急用药的潜力,为减少药物负担提供了一个有效的非药物治疗选择。

关键词：慢性自发性荨麻疹针刺二次分析抗组胺药综合管理策略

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碳纤维导电纸的研究现状及其应用

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化工新型材料 2014年第4期42卷 192-194,197页

作者：施云舟王彪东华大学纤维材料改性国家重点实验室上海201620

和其他碳纤维复合材料相比,由于碳纤维导电纸具有轻薄柔软,可复合性强的优点,因此在许多领域都得到了广泛应用。基于碳纤维导电纸的不同应用领域,主要介绍了碳纤维导电纸的性能特点、制备工艺及其在各领域内的研究进展,同时对碳纤维导... 详细信息

和其他碳纤维复合材料相比,由于碳纤维导电纸具有轻薄柔软,可复合性强的优点,因此在许多领域都得到了广泛应用。基于碳纤维导电纸的不同应用领域,主要介绍了碳纤维导电纸的性能特点、制备工艺及其在各领域内的研究进展,同时对碳纤维导电纸的前景进行了展望。

关键词：碳纤维导电纸燃料电池功能导电材料应用

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