Efficacy of acupuncture in refractory irritable bowel syndrome patients:a randomized controlled trial

作     者：Jun Zhao Hui Zheng Xin Wang Xuefei Wang Yunzhou Shi Chaorong Xie Qingfeng Tao Da Li Jingwen Sun Junjian Tian Junxia Gao Huimin Liu Suhua Shi Jinxia Ni Rongdan Xue Hui Hu Min Chen Shuguang Yu Zhigang Li 

作者机构：School of Acupuncture-Moxibustion and TuinaBeijing University of Chinese MedicineBeijing100029China The Third Hospital/Acupuncture and Tuina SchoolChengdu University of Traditional Chinese MedicineChengdu610000China Beijing Hospital of Traditional Chinese MedicineCapital Medical UniversityBeijing100010China Department of Acupuncture and MoxibustionDongzhimen Hospital Affiliated to Beijing University of Chinese MedicineBeijing100700China Department of RehabilitationThe Third Affiliated Hospital of Beijing University of Chinese MedicineBeijing100029China Department of Acupuncture and MoxibustionDongfang Hospital Affiliated with Beijing University of Chinese MedicineBeijing100078China Anorectal Disease DepartmentHospital of Chengdu University of Traditional Chinese MedicineChengdu610075China Department of Integrated Traditional and Western MedicineWest China HospitalSichuan UniversityChengdu610044China 

出 版 物：《Frontiers of Medicine》 (医学前沿（英文版）)

年 卷 期：2024年第18卷第4期

页      面：678-689页

核心收录：

学科分类：1005[医学-中医学] 100512[医学-针灸推拿学] 10[医学] 

基　　金：supported by the National Key R&D Program of China(No.2019YFC1709004) 

主　　题：acupuncture functional gastrointestinal disorders irritable bowel syndrome clinical trial 

摘      要：Previous studies have confirmed that acupuncture for irritable bowel syndrome(IBS)provided an additional benefit over usual care ***,we performed a multicenter,randomized,sham-controlled trial to assess the efficacy and safety of acupuncture versus sham acupuncture for refractory IBS in patients in the context of conventional *** in the acupuncture and sham acupuncture groups received real or sham acupuncture treatment in 3 sessions per week for a total of 12 *** primary outcome was a change in the IBS–Symptom Severity Scale(IBS-SSS)score from baseline to week 4.A total of 521 participants were screened,and 170 patients(85 patients per group)were enrolled and included in the intention-to-treat *** characteristics were comparable across the two *** baseline to 4 weeks,the IBS-SSS total score decreased by 140.0(95%CI:126.0 to 153.9)in the acupuncture group and 64.4(95%CI:50.4 to 78.3)in the sham acupuncture *** between-group difference was 75.6(95%CI:55.8 to 95.4).Acupuncture efficacy was maintained during the 4-week follow-up *** were no serious adverse *** conclusion,acupuncture provided benefits when combined with treatment as usual,providing more options for the treatment of refractory IBS.