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单孔胸腔镜治疗支气管扩张症的效果研究

系统医学 2024年第11期9卷 102-105页

作者：张岚毛宁徐友迪杨胜珍青岛市胶州中心医院胸外科山东青岛266300

目的研究单孔胸腔镜治疗支气管扩张症的效果。方法选取2022年1月—2023年6月青岛市胶州中心医院胸外科收治的56例支气管扩张症患者为研究对象,遵照掷骰子法平均分为两组,各28例。对比组选用传统开胸手术治疗,治疗组选用单孔胸腔镜治... 详细信息

目的研究单孔胸腔镜治疗支气管扩张症的效果。方法选取2022年1月—2023年6月青岛市胶州中心医院胸外科收治的56例支气管扩张症患者为研究对象,遵照掷骰子法平均分为两组,各28例。对比组选用传统开胸手术治疗,治疗组选用单孔胸腔镜治疗。比较两组肺功能指标、症状评分、时间指标、治疗有效性、并发症发生率。结果治疗后,治疗组各项肺功能指标高于对比组,差异有统计学意义(P均<0.05)。治疗组各项症状评分低于对比组,差异有统计学意义(P均<0.05)。治疗组各项时间指标短于对比组,差异有统计学意义(P均<0.05)。治疗组的治疗有效性为96.43%,高于对比组的75.00%,差异有统计学意义(χ^(2)=5.250,P<0.05)。治疗组的并发症发生率低于对比组,差异有统计学意义(P<0.05)。结论执行单孔胸腔镜治疗,可以使支气管扩张症患者的肺功能得到改善,缓解咳嗽症状,同时,还可提高治疗有效性,减少并发症情况,缩短住院时间。

关键词：单孔胸腔镜治疗支气管扩张症肺功能指标治疗有效性并发症发生率

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Optimum linear array of an optical aperture synthesis telescope

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Chinese Science Bulletin 2002年第23期47卷 1964-1968页

作者： WEN Jianguo JIN shengzhen NING Shunian National Astronomical Observatory Chinese Academy of SciencesBeijing 100012China China University of Mining and Technology Beijing 100083China

Measuring out successively the degree of coherence of the source produced by any couple of the small apertures via rotating an array composed of the small aperture telescopes, and synthesizing them into the (u, v) coverage of the source, the brightness distribution of the source can be obtained by the inverse Fourier transform of the degree of coherence with much higher resolution than from a single telescope. This article discusses the arrangements of the small apertures in the linear array, and found a method to decide the quality of the arrangements, the judgment factorε is introduced to calculate the arrangements in quantity. There are 1.5x1011 possibilities for 11 apertures. Therefore, the computer procedures are programmed to select the optimum arrangements. The effect of the simulation of the aperture synthesis is given for the linear array. The simulation method can also be used in the nonlinear arrays.

关键词： optical aperture synthesis optimum linear array judgment factor (u v)-spectrum sampling point spread function.

小麦替代部分玉米对藏羊生长性能、表观消化率和血清生化指标的影响

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中国粮油学报 2024年第4期39卷 103-109页

作者：张峰硕马博妍吴振岭陈渲朱凯娜王志有侯生珍桂林生青海大学农牧学院西宁810016

本实验旨在研究小麦替代精料中部分玉米对藏羊生长性能、表观消化率、血清生化指标和脏器发育的影响。选取60只初始体质量相近,健康无病的2~3月龄藏羊,随机分成2组,每组30只,每组5个重复。对照组饲喂玉米型基础日粮,实验组饲喂质量分数... 详细信息

本实验旨在研究小麦替代精料中部分玉米对藏羊生长性能、表观消化率、血清生化指标和脏器发育的影响。选取60只初始体质量相近,健康无病的2~3月龄藏羊,随机分成2组,每组30只,每组5个重复。对照组饲喂玉米型基础日粮,实验组饲喂质量分数为10%小麦替代精料中部分玉米。实验期100 d,其中预饲期10 d,正试期90 d。结果表明:1)实验组的终末体质量、平均日增重、体长和体躯指数显著高于对照组(P<0.05)。2)实验组中粗蛋白、粗纤维、中性洗涤纤维、酸性洗涤纤维和粗灰分的表观消化率显著高于对照组(P<0.05)。3)实验组中谷草转氨酶显著低于对照组(P<0.05)。4)瘤胃质量和皱胃质量实验组显著高于对照组(P<0.05)。因此,在藏羊日粮中添加质量分数为10%小麦粉替代精料中部分玉米能有效提高藏羊的表观消化率,从而使藏羊对其日粮的利用率增加提高其生长性能和脏器质量,同时还能降低血清中谷草转氨酶含量从而改善肝脏功能,以维持藏羊正常的消化代谢。

关键词：藏系绵羊营养调控小麦生长发育营养消化率血清生化指标

Selective probes targeting c-MYC Pu22 G-quadruplex and their application in live mice imaging

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Chinese Chemical Letters 2022年第3期33卷 1627-1631页

作者： Zhuo Yu Wenbo Huang Liqiao Shi Shaoyong Ke shengzhen Xu National Biopesticide Engineering Research Centre Hubei Biopesticide Engineering Research CentreHubei Academy of Agricultural SciencesWuhan 430064China College of Science Huazhong Agricultural UniversityWuhan 430070China

Several probes containing benzothiazole-guided conjugated systems(BGCS) were designed and synthesized, and two molecules(BGCS5 and BGCS6) of which were discovered as selective probes targeting c-MYC Pu22 G-quadruplex DNA. The fluorescence intensity of BGCS5 and BGCS6 in the presence of c-MYC Pu22 far exceeds that of the typical G4 probe TO1. Especially, the fluorescence of BGCS6 increased almost193-fold in the presence of c-MYC Pu22 G4 compared to that alone in aqueous buffer condition with almost no fluorescence and 10–30 folds than those in the presence of other DNAs, which will be useful tools for disease detection in mammals.

关键词： Benthiazole Conjugated system Chemosensor G-quadruplex DNA In vivo imaging

柴芍胃康汤联合四联疗法治疗肝胃气滞证Hp阳性慢性萎缩性胃炎的疗效观察

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中国医院用药评价与分析 2024年第3期24卷 308-311页

作者：王维张瑜孙胜振华元鑫邯郸市中医院治未病中心河北邯郸056002 邯郸市中医院脾胃病科河北邯郸056002

目的:观察柴芍胃康汤联合四联疗法治疗肝胃气滞证幽门螺杆菌(Hp)阳性慢性萎缩性胃炎(CAG)的疗效及对患者胃泌素-17(G-17)、丙二醛(MDA)、胃蛋白酶原(PG)Ⅰ和PGⅡ水平,胃黏膜组织病理和Hp根除的影响。方法:选取2021年6月至2023年5月该院... 详细信息

目的:观察柴芍胃康汤联合四联疗法治疗肝胃气滞证幽门螺杆菌(Hp)阳性慢性萎缩性胃炎(CAG)的疗效及对患者胃泌素-17(G-17)、丙二醛(MDA)、胃蛋白酶原(PG)Ⅰ和PGⅡ水平,胃黏膜组织病理和Hp根除的影响。方法:选取2021年6月至2023年5月该院收治的肝胃气滞证Hp阳性CAG患者140例,按随机数字表法分为联合组和对照组(各70例)。对照组患者给予标准四联疗法,联合组患者在对照组的基础上给予柴芍胃康汤治疗。比较两组患者治疗前后血清G-17、MDA、PGⅠ和PGⅡ水平,胃黏膜组织病理评分、Hp根除率,观察安全性和临床疗效。结果:治疗后,两组患者血清G-17、PGⅠ水平明显升高,MDA、PGⅡ水平和胃黏膜组织病理评分明显降低;且联合组患者血清G-17、PGⅠ水平较对照组升高,MDA、PGⅡ水平和胃黏膜组织病理评分较对照组降低,差异均有统计学意义(P<0.05)。联合组患者的Hp根除率、总有效率分别为92.86%(65/70)、92.86%(65/70),明显高于对照组的81.43%(57/70)、81.43%(57/70),差异均有统计学意义(P<0.05)。结论:柴芍胃康汤联合四联疗法治疗肝胃气滞证Hp阳性CAG的疗效较好,可改善患者胃功能、氧化应激和胃黏膜组织病理损伤,并可有效提高Hp根除率。

关键词：柴芍胃康汤四联疗法肝胃气滞证幽门螺杆菌阳性慢性萎缩性胃炎临床疗效

Progress on Space Solar Telescope in 2002-2004

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空间科学学报 2004年第Z1期24卷 60-63页

作者： AI Guoxiang YAN Yihua JIN shengzhen National Astronomical Observatories The Chinese Academy of Sciences Beijing 100012 China National Astronomical Observatories The Chinese Academy of Sciences Beijing 100012 China National Astronomical Observatories The Chinese Academy of Sciences Beijing 100012 China

The progress on Chinese Space Solar Telescope (SST) in 2002-2004 is introduced. The documentations on plans and outlines based on the standards of Chinese aerospace industry for SST mission has been fulfilled. The key technical problems of SST satellite platform and payloads are tackled during pre-study stage of the mission. The laboratory assembly and calibration of the main optical telescope of 1.2 m spherical mirror and 1 m plain mirror have been carried out with the accuracy of λ/40 and λ/30, respectively. The prototype at 17.1 nm for extreme ultraviolet telescope is under development and manufacture with a diameter of 13 cm. Its primary and secondary mirrors have a manufacturing error of 5nm with a roughness degree of less than 0.5 nm and a multiplayer reflection factor of better than 20%. The on-board scientific data processing unit has been developed. Prototypes for other payloads such as H and white light telescope, wide band spectroscopy in high energy and solar and interplanetary radio spectrometer have been developed accordingly.

关键词： Space telescope, Instrument, Astronoming, Solar physics

Atmospheric HONO formation during and after the Spring Festival holidays in a coastal city of China

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Journal of Environmental Sciences 2023年第5期127卷 251-263页

作者： Xue Ni Cuizhi Sun Yongyun Zhang Baoling Liang shengzhen Zhou Guangdong Lan Jun Zhao School of Atmospheric Sciences Guangdong Province Key Laboratory for Climate Change and Natural Disaster Studiesand Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)Sun Yat-sen UniversityZhuhai 519082China Guangdong Provincial Observation and Research Station for Climate Environment and Air Quality Change in the Pearl River Estuary Zhuhai 519082China Key Laboratory of Tropical Atmosphere-Ocean System Ministry of EducationZhuhai 519082China

Nitrous acid(HONO)is an important source of hydrogen oxides(HOx),which affects air quality,the atmospheric oxidation capacity,and human ***,we present ambient measurements of the HONO concentrations in Zhuhai,a coastal city in Southern China,from February 7 to March 15,*** campaign was classified into two periods during(P1)and after(P2)the Spring Festival *** average HONO mixing ratio during P2(1.19±0.85 ppbv)was much higher than that during P1(0.24±0.18 ppbv),likely due to the contribution of homogeneous HONO *** nighttime,the heterogeneous conversion rate during P2(0.0089/hr)was considerably higher than that during P1(0.0057/hr),suggesting a higher heterogeneous NO_(2) conversion ***,the heterogeneous NO_(2) conversion was the dominant way during P1 with a high percentage of 88%,while comparable ratios of heterogeneous and homogeneous formation were found(54%vs.46%)during P2,indicating that the homogeneous formation was also important during *** daytime,homogeneous reaction was the major known pathway,with a contribution of 16%during P1 and 27%during P2,leaving large unknown HONO sources which reasonably correlated with the photo-enhanced NO_(2) *** case scenarios were additionally explored,showing that there might be a primary emission source during one scenario(February 17-18)and vehicle emissions might be the major unknown HONO source for another scenario(March 3–5).The results suggest that large unknown daytime sources still exist which need more future ambient and laboratory studies.

关键词： Nitrous acid Nocturnal and daytime budget Heterogeneous conversion Homogeneous formation Coastal area

日粮中添加益生素对藏羊羔羊生长性能和瘤胃细菌结构与功能的影响

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四川农业大学学报 2024年第2期42卷 442-447页

作者：周力侯生珍吴振岭闫小兰桂林生王志有青海大学农牧学院西宁810016

【目的】旨在研究日粮中添加0.2%益生素对藏羊羔羊生长发育及其瘤胃细菌多样性的影响。【方法】选择体重相近且健康状况良好的3月龄藏羊60只,随机分为两组,每组30只。对照组饲喂基础日粮(C组),益生素组在基础日粮中添加0.2%产酶益生素(T... 详细信息

【目的】旨在研究日粮中添加0.2%益生素对藏羊羔羊生长发育及其瘤胃细菌多样性的影响。【方法】选择体重相近且健康状况良好的3月龄藏羊60只,随机分为两组,每组30只。对照组饲喂基础日粮(C组),益生素组在基础日粮中添加0.2%产酶益生素(T组)。90 d饲喂试验结束时,每组随机选择6只试验羊屠宰取瘤胃内容物,通过16S rDNA高通量测序技术分析微生物群落的变化。【结果】①T组的终末体重、平均日增重显著高于C组(P0.05);③C组的厚壁菌门(Firmicutes)、普雷沃氏菌科(Prevotellaceae)相对丰度显著低于T组(P<0.05),而C组的变形菌门(Proteobacteria)相对丰度显著高于T组(P<0.05)。【结论】日粮中添加0.2%益生素能够明显促进藏羊羔羊的生长性能,并在一定程度上能够增加瘤胃有益菌的丰度。

关键词：瘤胃微生物 16S rDNA 藏羊生产性能益生素

饲粮蛋白质水平对藏羊生长性能、血清生化指标及肉品质的影响

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饲料工业 2024年第3期45卷 49-55页

作者：陈渲吴振岭周力朱凯娜侯生珍王志有桂林生青海大学农牧学院青海西宁810016 宁夏大学动物科技学院宁夏银川750021

试验旨在探究不同蛋白质水平饲粮对藏羊生长性能、血清生化指标和肉品质的影响。试验选用初始体重相近[(15.40±0.81)kg]且体况良好的2月龄高原型藏羊公羔90只,随机分为3个组,每组5个重复。各组分别饲喂蛋白质水平为12%(A组)、14%(B组)... 详细信息

试验旨在探究不同蛋白质水平饲粮对藏羊生长性能、血清生化指标和肉品质的影响。试验选用初始体重相近[(15.40±0.81)kg]且体况良好的2月龄高原型藏羊公羔90只,随机分为3个组,每组5个重复。各组分别饲喂蛋白质水平为12%(A组)、14%(B组)和16%(C组)的饲粮。整个试验分预试期7 d和正试期90 d。结果显示:①各组间的平均日增重、平均日采食量及料重比均差异不显著(P>0.05)。②A组的血清谷丙转氨酶活性高于B组(P>0.05)和C组(P0.05)。③C组的肌肉中糖原含量显著高于A组(P<0.05),C组的肌肉中苹果酸脱氢酶活性显著高于其他两组(P<0.05)。④C组的肌纤维直径显著高于B组(P<0.05),B组和C组的肌纤维密度显著高于A组(P<0.05),B组的肌纤维横截面积显著高于C组(P<0.05)。综上,饲粮蛋白水平为16%时,有利于增强藏羊的生长性能。在饲粮蛋白水平为14%时,有利于增强育肥期藏羊肌肉品质。

关键词：藏羊蛋白水平生长性能血清生化指标糖酵解肌纤维酶活性