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A pH-Regulated Colorimetric Sensor Array for Discrimination of Biothiols Based on Two Different-Sized β-Cyclodextrin-Functionalized AuNPs

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Journal of Analysis and Testing 2023年第2期7卷 101-109页

作者： Hang Li Chao Zhao shengnan wei Xingxing Liu Juan Li Juan Wang School of Public Health Jilin UniversityChangchun 130021China The Department of Cadre Ward The First Hospital of Jilin UniversityChangchun 130021China

The abnormal changes of biothiols are directly related to health condition of human body,and the effective identification and quantification of biothiols is of great significance for screening and diagnosis of *** study described the development of a p H-regulated colorimetric sensor array for discrimination of five kinds of biothiols including cysteine(Cys),glutathione(GSH),homocysteine(Hcy),cysteamine(CA)and N-acetylcysteine(NAC).The proposed sensor array was established using 5-nm-and 20-nm-sizedβ-cyclodextrin-functionalized gold nanoparticles(β-CD@Au NPs)as nonspecific receptor and signal transduction *** to the different binding affinity between biothiols andβ-CD@Au NPs in various p H environments,the different aggregation behaviors of nanoparticles produced unique colorimetric response patterns,which were able to be distinguished by bare eyes and UV-vis ***,principal component analysis(PCA)and hierarchical cluster analysis(HCA)were employed for pattern recognition and generated a clustering map for a clear differentiation of biothiols at the level ofμmol/***,it can be proved that the method was successfully applied to the analysis of biothiols in human urine samples.

关键词： Colorimetric sensor array Biothiols β-Cyclodextrin-functionalized AuNPs Principal component analysis

Effect of Oxygen-Rich Combustion on Flame Propagation of Syngas in a Half-Open Pipe at Elevated Temperatures

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Journal of Thermal Science 2024年第5期33卷 1920-1934页

作者： LI Ningning DENG Haoxin XU Zhuangzhuang YAN Mengmeng wei shengnan SUN Guangzhen WEN Xiaoping GAN Haowen WANG Fahui School of Mechanical and Power Engineering Henan Polytechnic UniversityJiaozuo 454003China

The investigation of syngas flame propagation has great benefits for the effective use of gas *** essay sets out to study the flame propagation of premixed oxygen-rich combustion(oxygen enrichment coefficient in volumeΩ:0.21,0.27,0.32,0.37)of syngas(H_(2):CO=2:8)in half-closed rectangular ducts at elevated temperatures(T:300 K,400 K,500 K)and evaluate the effects of initial temperature and oxygen enrichment coefficient on the LBV from sensitivity analysis and kinetic *** paper presents the effect of the expansion effect on laminar burning velocity for the first time,and separates the effect of the expansion effect on laminar burning velocity by a new *** shows that as the initial temperature goes up,the faster the exponential growth phase of the flame front velocity,the slower the slow growth *** smaller and earlier the maximum flame front velocity arrives,the slower the average flame speed *** the oxygen enrichment coefficient goes up,the peak value of the flame front velocity gradually ***-rich combustion and increasing initial temperature inhibit flame propagation in a half-open tube,but promote laminar burning velocity,which increases the key chemical bond and adiabatic flame *** net reaction rate shows that oxygen-rich combustion mainly promotes the combustion reaction of H_(2)(R2).However,increasing the initial temperature mainly promoted the oxidation of CO(R29).Analysis of the reaction path showed that oxygen-rich combustion and increased initial temperature promoted the reaction of H_(2)and CO with key chemical bonds,increased OH concentration,and inhibited OH cracking reaction.

关键词： gas turbines oxyfuel combustion numerical simulation combustion kinetics fire and flame

Microwave synthesis of chain-like zircona nanofibers through carbon-induced self-assembly growth

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Frontiers of Materials Science 2017年第4期11卷 353-357页

作者： Wanyu ZHAO Jian LI Bingbing FAN Gang SHAO Hailong WANG Bozhen SONG shengnan wei Rui ZHANG School of Materials Science and Engineering Zhengzhou University Zhengzhou 450001 China Henan Key Laboratory of Aeronautical Material and Application Technology Zhengzhou University of Aeronautics Zhengzhou 450046 China

Chain-like zircona （ZrO2） nanofibers were prepared by microwave sinter- ing without any surfactants or solid templates. Microwave sintering was conducted in a multimode microwave cavity with TE666 resonant mode at 2.45 GHz. Carbon particles were used to activate unique thermal processes when mixed with ZrO2 precursor. The sintering condition was at 1300℃ for 10 min. Samples were characterized by XRD, SEM, TEM techniques. It was found that both monolithic and tetragonal ZrO2 co-existed in samples prepared from the mixture of ZrO2 precursors and carbon by either microwave or conventional sintering. Only m-ZrO2 exists in samples prepared by ZrO2 precursors without carbon. ZrO2 appeared as chain-like nanofibers, which might be attributed to a so- called carbon-induced self-assembly growth mechanism.

关键词： ZrO2 chain-like nanofibers microwave sintering carbon-induced self-assembly growth

Decellularized lung scaffold-based fibroblasts co-culture method promotes invasion and metastases of human non-small cell lung cancer in vitro

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解剖学杂志 2021年第S1期44卷 153-154页

作者： Guo Lina wei shengnan Jiao Hui Wang Xuili College of Basic Medical Sciences Dalian Medical UniversityDalian 116044China

Tumor invasion and metastases is one of the leading causes of tumor-related death while non-small cell lung cancer(NSCLC)is prone to multiple metastases.T umor microenvironment(TEM),especially extracellular matrix(ECM)***,plays an important role in tumor metastases and *** better understand the mechanism of NSCLC lung metastases and invasion,we constructed a three-dimensional(3D)co-culture model by seeding A549 tumor cells and human bronchial fibroblasts into decellularized lung *** showed that decellularized mice lung scaffolds retaining intact structure and ECM components,provided a suitable microenvironment for maintaining the viability,morphology of both cells in vitro.3D architecture and pulmonary ECM promoted the mobility/invasion ability of A549 cells by up-regulating the expression of matrix metalloproteinases(MMPs).Meanwhile,factors in TGF-1/Smad4 pathway were significantly up-regulated which may associated with epithelial-mesenchymal transition(EMT)of A549 cells.

关键词： invasion metastases lung

Decellularized lung scaffold-based fibroblasts co-culture method promotes invasion and metastases of human non-small cell lung cancer in vitro

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Decellularized lung scaffold-based fibroblasts co-culture me...

Serum electrolytes and the risk of in-hospital mortality in patients with decompensate heart failure

中国解剖学会2021年年会

作者： Guo Lina wei shengnan Jiao Hui Wang Xuili College of Basic Medical Sciences Dalian Medical University

Tumor invasion and metastases is one of the leading causes of tumor-related death while non-small cell lung cancer (NSCLC) is prone to multiple *** microenvironment (TEM),especially extracellular matrix (ECM) and fibr...

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Serum electrolytes and the risk of in-hospital mortality in ...

中华医学会第五次全国重症医学大会

作者： Shenzhen Peoples Hospital Chen HuaiSheng Zhang QinMei Xue Meng Wu shengnan Wang wei

Introduction This study aimed to assess health-related quality of life(HRQOL) in trauma patients two years after discharge from an intensive care unit(ICU) in Zunyi, China and to investigate possible determinants of *** Retrospective analysis data of 261 cases of decompensate heart failure with NYHA classⅢ-Ⅳthat were included between January 2003 and December 2004 at Shenzhen People’s Hospital,*** participants were grouped in accordance with survival or death. We studied the relationship between serum potassium,sodium and calcium levels

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基于注意力及边缘提取任务的实时分割网络

计算机工程与应用 2023年第22期59卷 213-222页

作者：文凯杨一鹏熊俊臣韦胜男重庆邮电大学通信与信息工程学院重庆400065 重庆邮电大学通信新技术应用研究中心重庆400065

针对小目标分割精度不高且分割边界模糊等问题,对BiSeNet V3进行改进,提出了一种基于全局注意力及边缘提取任务的实时分割网络。结合非对称卷积,对短期密集拼接模块做了轻量化处理,并通过全局注意力增强了特征的全局相关性。边缘分支可... 详细信息

针对小目标分割精度不高且分割边界模糊等问题,对BiSeNet V3进行改进,提出了一种基于全局注意力及边缘提取任务的实时分割网络。结合非对称卷积,对短期密集拼接模块做了轻量化处理,并通过全局注意力增强了特征的全局相关性。边缘分支可通过边缘特征融合模块有效滤除语义特征中与边界无关的信息,并在解码阶段恢复损失的细节信息。改进的损失函数保证了网络能够向着利于小目标分割的方向更新参数。在数据集上的结果及真实环境预测表明,所提网络改善了边界清晰度及小目标分割精度,并在真实场景下仍具有较高鲁棒性。

关键词：小目标边界模糊全局注意力边缘提取任务

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无偿献血初筛血型错误原因分析

中国输血杂志 2014年第4期27卷 431-432页

作者：刘冬曾付芳魏胜男十堰市中心血站湖北十堰442000

目的分析无偿献血采血点初筛血型错误的原因，制定预防措施减少错型发生，保障输血安全。方法2004年10月30日～2013年10月30日9年对289938名无偿献血者的血型初筛结果与复检结果进行对比分析，探讨错型原因。结果259例初筛血型与复检不... 详细信息

目的分析无偿献血采血点初筛血型错误的原因，制定预防措施减少错型发生，保障输血安全。方法2004年10月30日～2013年10月30日9年对289938名无偿献血者的血型初筛结果与复检结果进行对比分析，探讨错型原因。结果259例初筛血型与复检不符，初筛错型原因反应不充分，误判误填，试剂间污染，漏加反加试剂162（62．55％）。结论针对错误环节，从人员、环境、试剂等多方面着手，采取综合措施，减少血型差错，降低初筛错型率。

关键词：无偿献血血型错误

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水泥辊压机电气控制系统的改进设计

机械管理开发 2020年第2期35卷 179-180,191页

作者：魏胜男同煤集团建材有限责任公司山西大同037000

针对在实际生产中因辊压机耗能多、故障率高以及自动化程度低而严重威胁水泥产量和质量的问题,在分析辊压机系统组成及电气控制系统控制需求的基础上,完成了电气控制系统硬件设计中PLC及监测元器件的选型,以及软件设计中对主电机启停、... 详细信息

针对在实际生产中因辊压机耗能多、故障率高以及自动化程度低而严重威胁水泥产量和质量的问题,在分析辊压机系统组成及电气控制系统控制需求的基础上,完成了电气控制系统硬件设计中PLC及监测元器件的选型,以及软件设计中对主电机启停、液压系统卸荷、进料阀及出料阀等控制的程序流程图,为提升水泥生产的质量及产量奠定了扎实的基础。

关键词：水泥辊压机电气控制自动化可靠性