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Accidental discovery and isolation of Zika virus in Uganda and the relentless epidemiologist behind the investigations

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Virologica Sinica 2016年第4期31卷 357-361页

作者： Hedi Zhou Bryan Eaton Zhihong hu Basil Arif Wuhan Institute of Virology Chinese Academy of Sciences 6 Belvedere Terrace Ocean Grove Scientist Emeritus Laboratory for Molecular VirologyGLFCSault Ste.

INTRODUCTION Zika virus(ZIKV)has captured the attention of the world because of its potential to infect neural cells and its teratogenic effects on foetuses and the new *** virus seems to have various modes of transmission and has been the subject of many reviews in the literature(example,Musso and Gubler,2016,Wang et al.,2016).ZIKV was first isolated in1947 but remained almost

关键词： Accidental discovery and isolation of Zika virus in Uganda and the relentless epidemiologist behind the investigations

Cultivation of human liver cell lines with microcarriers acting as biological materials of bioartificial liver

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World Journal of Gastroenterology 1999年第3期5卷 221-224页

作者： Gao Y Xu XP hu HZ Yang JZ Mil Med Univ 1st Dept Gen Surg Zhujiang Hosp Guangzhou 510282 Guangdong Prov Peoples R China

AIM To improve the Cultivation efficiency and yield of human liver cell line *** High--density cultivation of CL--l onmicrocarriers was carried out with periodicobservation of their growth and *** specific functions of human liver cell werealso *** Cells of CL-1 cell line grew well onmicrocarrier Cytodex--3 and on the 7th day thepeak was reached. The amount of CLI cells was2.13 x 10’ and the total amount of albuminsynthesis reached 71 .23 ig, urea synthesis23 .32 mg and diazepam transformation 619 .7 ugrespectively. The yield of CL-l on microcarrierswas 49.3 times that of conventional *** amounts of albumin synthesis, ureasynthesis and diazepam transformation were39.8 times, 41 .6 times and 33.3 times those ofconventional Cultivation, *** The human liver cell line CL--1 canbe Cultivated to a high density with Cytodex--3and has better biological functions. High-densityCultivation of CLI on microcarriers can act asthe biological material of bioartificial liver.

关键词： cell Figure

Predictive safety control for road vehicles after a tire blowout

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Science China(Information Sciences) 2018年第7期61卷 101-103页

作者： Fei WANG Hong CHEN Lulu GUO Yunfeng hu State Key Laboratory of Automotive Simulation and Control Jilin University Department of Control Science and Engineering Jilin University

Since driver error is considered a major cause in over 90%of all road crashes[1],driving assistance systems are widely used to improve driving safety,and are an important research direction in the intelligent vehicle *** the rapid development of sensing,identification and communication technologies,the vehicle can obtain an increasing amount of information in real time,ranging from the vehicle status information to road information

关键词： Predictive safety control for road vehicles after a tire blowout

Effects of different concentrations of celecoxib on proliferation and cell cycle of SH-SY-5Y cells and its mechanisms In vitro study

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Neural Regeneration Research 2008年第2期3卷 133-137页

作者： hu Zhou Wei Wang Hongyi Wang Jinghua Li Department of Hematology Affiliated Hospital of Qingdao Medical College Qingdao University Qingdao 266003 Shandong Province China Department of Clinical Laboratory Qingdao Municipal Hospital Qingdao 266001 Shandong Province China

BACKGROUND： Highly selective cyclooxygenase-2 （COX-2） inhibitors have recently been approved for the treatment of colon cancer, breast cancer, urinary bladder cancer, and skin cancer. For the highly selective COX-2 celecoxib, the mechanism of action for inhibiting neuroblastoma cells is still uncertain. OBJECTIVE： To observe the influence of different celecoxib concentrations on proliferation and cell cycle of SH-SY-5Y cells in vitro and to reveal potential COX-2-independent mechanisms of celecoxib on SH-SY-5Y cells. DESIGN： Controlled experiment. SETTING： Department of Hematology, Affiliated Hospital of the Qingdao Medical College, Qingdao University, Shandong Province. MATERIALS： The study was performed at the Cerebrovascular Disease Institute of Shandong Province and the Laboratory of Molecular Biology, Affiliated Hospital of Qingdao Medical College, Qingdao University between September 2006 and June 2007. The SH-SY-5Y cell line was obtained from the Department of Molecular Biology, Qingdao Medical College, Qingdao University. Celecoxib was obtained from Pfizer Pharmaceuticals LLC, USA. Coulter DNA PREP reagent kit was purchased from Beckman Coulter, Inc. The antibodies against human CyclinD1, P21, and P16 were purchased from Santa Cruz Biotechnology. METHODS： SH-SY-5Y cells were treated with different concentrations of celecoxib （10, 20, 40, and 80 la mol/L） for 48 hours and comprised the experimental groups. The same concentrations of DMSO （dimethyl sulphoxide） treatment for 48 hours served as the control group. MAIN OUTCOME MEASURES： ① Cellular morphology of cells pre-treated and post-treated with celecoxib by inverted microscopy. ② Methabenzthiazuron assay was used to measure cell proliferation. ③ Cell cycle was measured by flow cytometry after incubation with different celecoxib concentrations for 48 hours. ④CyclinD1, P16, and P21 protein expression was detected by Western blot analysis. RESULTS： ① Cellular morphology： The shape of SH-SY-5Y cells pre

关键词： neuroblastoma cyclooxygenase celecoxib cyclins

The dependence of sintering temperature on Schottky barrier and bulk electron traps of ZnO varistors

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Science China(Technological Sciences) 2011年第2期54卷 375-378页

作者： LIU Jun HE JinLiang hu Jun LONG WangCheng State Key Laboratory of Power Systems Department of Electrical Engineering Tsinghua University Beijing 100084 China

In order to investigate the influence of sintering temperature on the Schottky barrier and bulk electron traps of ZnO varis- tors, ZnO-Bi2O3 based varistor ceramic samples were sintered at 1000, 1100, 1200 and 1300℃, respectively. The measured results indicate that the sample sintered at 1300℃ possesses the lowest voltage gradient and nonlinear coefficient, compared with other samples. The barrier height of the samples decreased as the sintering temperature increased, which resulted in the deterioration of nonlinearity. Furthermore, two bulk electron traps determined by admittance spectroscopy were generally independent of sintering temperature, which indicated that these two traps might originate from the intrinsic defects in ZnO lattice.

关键词： ZnO varistor sintering temperature Schottky barrier bulk electron trap admittance spectroscopy

Discovery and significance of microfossils from Qinbaikouian Dazhuang Formation in Luonan, Shaanxi Province

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Chinese Science Bulletin 1997年第3期42卷 243-245页

作者： Chen, Z hua, H Jian, WC hu, YX Department of Geology Northwest University Xi’an China Xi’an Institute of Geology and Mineral Resources Chinese Academy of Geological Sciences Xi’an China

THE microfossils were obtained by using 5%—7% HF acid from Qingbaikouian Dazhuang Formation in Luonan County, Shaanxi Province, with an age of 800—1000 Ma. The fossils may be one type of the oldest skeletal mierofos... 详细信息

关键词： microfossil Qinbaikouian Dazhuang Formation Shaanxi Province.

Analysis of Two Public Key Cryptosystems Based on Randomized Knapsack Sequences

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Chinese Journal of Electronics 2014年第1期23卷 175-178页

作者： PENG Liqiang ZUO Jinyin hu Lei XU Jun State Key Laboratory of Information Security Institute of Information Engineering Chinese Academy of Sciences PLA Unit 95899

Two knapsack public key cryptosystems based on randomized knapsack sequences were proposed in2009 and 2011 respectively, where the secret knapsack sequence is transformed by secret modular linear transforms into one or three public randomized knapsack sequences with appropriate density. In this paper, we recover the secret modular linear transforms by simultaneous Diophantine approximation and propose secret key recovery attacks on these two cryptosystems. Practical attack experiments are done within one minute.

关键词： Knapsack public key cryptosystem Simultaneous Diophantine approximation Lattice L3 algorithm

A new optical field state as an output of diffusion channel when the input being number state

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Science China(Physics,Mechanics & Astronomy) 2014年第9期57卷 1649-1653页

作者： FAN HongYi LOU SenYue PAN XiaoYin hu LiYun Department of Physics Ningbo University Department of physics Jiangxi Normal University

By analyzing theoretical scheme of quantum controlling through photon addition,we propose a new optical field whose density operator asρ=λ(1-λ)l:Ll(-λ2aa/1-λ)e-λaa:(here::denotes normal ordering symbol),which is named Laguerre-polynomialweighted chaotic *** show that such state is the solution to the master equation d/dtρ=-κ(aaρ+ρaa-aρa-aρa),describing a diffusion channel,with the initial number state|l l|,andλ=1/(1+κt).This new state is characteristic of possessing photon number l+κt at time t,so the photon number by adjusting the diffusion parameterκcan be *** master equation is solved using the summation method within ordered product of operators and the entangled state *** physical difference between the diffusion and the amplitude damping is noted.

关键词： photon addition Laguerre-polynomial-weighted chaotic state entangled state representation

Consensus-Based Distributed Secondary Control of Microgrids: A Pre-assigned Time Sliding Mode Approach

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IEEE/CAA Journal of Automatica Sinica 2024年第12期11卷 2525-2527页

作者： Xiangyong Chen Shunwei hu Xiangpeng Xie Jianlong Qiu IEEE the School of Automation and Electrical Engineering Linyi University the College of Information Science and Engineering Northeastern University the School of Internet of Things Technology Nanjing University of Posts and Telecommunications Nanjing

Dear Editor,This letter proposes an arbitrary pre-assigned time sliding mode approach to achieve distributed secondary control for microgrids with external disturbances. By constructing an effective time-varying gain function, we can set the convergence time arbitrarily to stabilize the system, which is without being affected by initial conditions and other design parameters.

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