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Chinese Chemical Letters 2009年第7期20卷 873-876页

作者： Wei Huang Yu Bo Cao Xiao Guang Zhang fa sheng li Huai Yang Department of Materials Physics and Chemistry School of Materials Science and Engineering University of Science and Technology Beijing Beijing 100083 China Beijing Yetop liquid Crystal Materials Co. Ltd. Beijing 101500 China

In this study, right-handed dicinnamate isosorbide was synthesized via the esterification reaction betweefi optically active isosorbide and cinnamate. The chiral dopant was characterized by FT-IR, ^1H NMR, elemental analysis, SEM, UV absorption spectrum. After dissolving in a nematic liquid crystal mixture, the chiral dopant exhibited a temperature-dependent solubility in the chiral nematic liquid crystal mixture. Meanwhile, a relatively high value of helical twisting power of the polymerizable chiral dopant was determined. The results show that the chiral dopant has great potential in achieving a polymer stabilized chiral nematic liquid crystal film with a broad-band selective reflection. C 2009 Huai Yang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

关键词： Chiral dopant Temperature-dependent solubility liquid crystal Helical twisting power

Relationship between Renalase Expression and Kidney Disease： an Observational Study in 72 Patients Undergoing Renal Biopsy

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Current Medical Science 2018年第2期38卷 268-276页

作者： Yi-sha HUANG Jian-bo LAP sheng-fa li Ting WANG Ying-nan liU Qing-xia ZHANG Shu-yuan ZHANG Chun-han SUN Nan HU Xin-zhou Zhang Department of Nephrology Shenzhen People 's Hospital Second Clinical Medical College of Jinan University Shenzhen 518000 China. Key Renal Laboratory of Shenzhen Shenzhen 518108 China. Department of Gastrointestinal Shenzhen People 's Hospital Second Clinical Medical College of Jinan University Shenzhen 518000 China. Department of Orthopedics Huizhou First Hospital Affiliated Hospital of Guangdong Medical University Huizhou 516000 China. Department of Cell Biology School of Basic Medical Science Southern Medical University Guangzhou 510515 China. Department of Hand Microsurgry Shenzhen People 's Hospital Second Clinical Medical College of Jinan University Shenzhen 518000 China.

The relationship between the levels of renalase and changes in proteinuria, hypertension, renal function, renal tubular epithelial cell apoptosis and B-cell lymphoma-2 （Bcl-2） expression was investigated in patients （chronic nephritis, primary nephrotic syndrome or other kidney disease） that underwent renal biopsy. The study group comprised 72 patients undergoing renal biopsy. Patient profiles and renal function were collected. Concentrations of renalase and Bcl-2 were measured by immunohistochemistry. Tubular injury was detected by periodic acid Schiff staining （PAS） and renal tubular epithelial cell apoptosis was assessed by TUNEL assay. The expression of renalase was significantly lower in renal biopsy specimens than in normal kidney tissues. There was a positive linear relationship between renalase and some serum and cardiac indices; a negative correlation was found between age, eGFR, Ccr and 24-h urinary protein. Renal tubule injury index and tubular epithelial cell apoptosis index showed a negative linear correlation with renalase. The results showed that renalase probably increased the expression of Bel-2. By two independent samples t-test, renalase levels were significantly increased in the non-hypertension group than in the hypertension group. One-way ANOVA showed that renalase expression was higher in samples with Lee＇s grade Ⅲ than in those with Lee＇s grade V. The expression of renalase was significantly decreased in patients who underwent renal biopsy, and was also associated with blood and renal function. The research proved that renalase may reduce renal tubular injury and apoptosis of renal tubular epithelial cells through the mitochondrial apoptosis pathway, finally achieving the purpose of delaying the progress of renal failure.

关键词： renalase kidney disease flavoprotein renal function renal puncture biopsy

Achieving further refinement of grain structure and improvement of mechanical properties in Al-12Si-4Cu-2Ni-1Mg alloy by Al-Ti-C-B master alloy addition and deep cryogenic treatment

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China Foundry 2025年第1期22卷 75-82页

作者： lin-fei Xia Wen-bo li Zuo-shan Wei Yu-ying Wu Xiang-fa liu China Key Laboratory for liquid-Solid Structural Evolution and Processing of Materials Ministry of EducationShandong UniversityJinan 250061China Shandong Key Laboratory of Advanced Aluminum Materials and Technology Binzhou Institute of TechnologyBinzhou 256600ShandongChina

Near-eutectic Al-Si alloys are widely used in automotive manufacturing due to their superior wear resistance and high temperature *** of high Si content,the grain refinement of near-eutectic Al-Si alloy has been a problem for many *** this study,the effect of deep cryogenic treatment(DCT)on the microstructure and mechanical properties of Al-12Si-4Cu-2Ni-Mg alloy with addition of Al-Ti-C-B master alloy was fully *** show that the average grain size of the alloy is greatly reduced from 0.92 mm to 0.50 mm,and the eutectic Si and Al7Cu4Ni precipitates are spheroidized and refined in Al-12Si-4Cu-2Ni-Mg after DCT for 24 h and aging *** these changes of microstructures result in a significant increment of about 22.5%in elongation and a slight enhancement of about 6.8%in tensile ***,the refinement of microstructure also significantly improves the fatigue life of the alloy.

关键词： deep cryogenic treatment near-eutectic Al-Si master alloy microstructure mechanical properties

Artificial self-powered and self-healable neuromorphic vision skin utilizing silver nanoparticle-doped ionogel photosynaptic heterostructure

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Journal of Semiconductors 2025年第1期46卷 205-213页

作者： Xinkai Qian fa Zhang Xiujuan li Junyue li Hongchao Sun Qiye Wang Chaoran Huang Zhenyu Zhang Zhe Zhou Juqing liu Key Laboratory of Flexible Electronics(KLoFE)&Institute of Advanced Materials(IAM) Nanjing Tech University(NanjingTech)Nanjing 211816China

Artificial skin should embody a softly functional film that is capable of self-powering,healing and sensing with neuromorphic ***,the pursuit of a bionic skin that combines high flexibility,self-healability,and zero-powered photosynaptic functionality remains *** this study,we report a self-powered and self-healable neuromorphic vision skin,featuring silver nanoparticle-doped ionogel heterostructure as *** localized surface plasmon resonance induced by light in the nanoparticles triggers temperature fluctuations within the heterojunction,facilitating ion migration for visual sensing with synaptic *** abundant reversible hydrogen bonds in the ionogel endow the skin with remarkable mechanical flexibility and self-healing *** assembled a neuromorphic visual skin equipped with a 5×5 photosynapse array,capable of sensing and memorizing diverse light patterns.

关键词： neuromorphic vision skin ionogel heterojuction lspr photosynapse

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保证山场合理造材的有效措施

吉林林业科技 2001年第4期30卷 56-57页

作者：盛立发吉林省珲春林业局吉林延边133300

保证山场合理造材的有效措施是 :林业局要建立一支强有力的检量员队伍 ,由林业局检验站统一管理 ,并建立一套相适宜的制约激励机制 ,才能消除长材短造、优材劣造。

关键词：山场合理造材检量员队伍激励机制

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铁纳米线磁行为的微磁学模拟与研究

物理学报 2001年第8期50卷 1605-1609页

作者：肖君军孙超薛德胜李发伸兰州大学教育部磁学与磁性材料重点实验室兰州730000

通过微磁学模拟的手段对用电化学沉积法制备出的呈圆柱形的铁纳米线在常温下的磁行为进行了系统的研究 ,结果表明不同形状参量的铁纳米线都表现出磁各向异性 ,矫顽力随纳米线直径变化近似呈现平方反比关系 ,而对每一固定的直径 ,矫顽力... 详细信息

通过微磁学模拟的手段对用电化学沉积法制备出的呈圆柱形的铁纳米线在常温下的磁行为进行了系统的研究 ,结果表明不同形状参量的铁纳米线都表现出磁各向异性 ,矫顽力随纳米线直径变化近似呈现平方反比关系 ,而对每一固定的直径 ,矫顽力随纳米线长度的增加而增大 ,最后趋向定值 .磁滞回线形状、静态磁矩分布和反转机制等都随纳米线的直径和长度的变化而变化 ,对相应的规律给出了明确的解释 .模拟结果显示实验上尚不能制备出的直径为 5nm的纳米线呈现一致反转机理。

关键词：铁纳米线微磁学磁行为模拟磁性纳米材料

孟加拉湾中部表层沉积物有机碳分布特征及来源

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海洋科学进展 2017年第1期35卷 73-82页

作者：李景瑞刘升发胡利民冯秀丽孙兴全白亚之石学法中国海洋大学海洋地球科学学院山东青岛266100 海底科学与探测技术教育部重点实验室山东青岛266100 国家海洋局第一海洋研究所山东青岛266061 海洋沉积与环境地质国家海洋局重点实验室山东青岛266061 青岛海洋科学与技术国家实验室海洋地质过程与环境功能实验室山东青岛266061

通过对孟加拉湾中部110个表层沉积物样品有机碳、氮含量及粒度进行测试分析,揭示了研究区表层沉积物平均粒径、有机碳(TOC)、总氮(TN)、有机碳/总氮(TOC/TN)的分布特征,并讨论了其有机质来源及控制因素。结果表明,研究区表层沉积物的平... 详细信息

通过对孟加拉湾中部110个表层沉积物样品有机碳、氮含量及粒度进行测试分析,揭示了研究区表层沉积物平均粒径、有机碳(TOC)、总氮(TN)、有机碳/总氮(TOC/TN)的分布特征,并讨论了其有机质来源及控制因素。结果表明,研究区表层沉积物的平均粒径值为6.2~7.6Φ,平均为7.1Φ,其分布呈现出以16°N和15°N为界南北两侧海域粒度相对较细(>7Φ),中间海域相对较粗(<7Φ)的特点;研究区TOC的质量分数为0.37%~1.24%,平均为0.84%,TN质量分数为0.05%~0.15%,平均为0.10%,两者分布特点相似,大致以15°N和16°N为界表现出南北两侧海域高,中间海域低的特点;TOC/TN比值为6.05~12.88,平均为8.38,中部海域比值高,南北两侧低。根据TOC/TN比值估算研究区陆源和海洋自生有机质的贡献,结果表明研究区陆源与海洋自生有机质平均相对贡献分别为60%和40%。研究区有机质的分布主要受控于有机质来源及输运方式,其中浊流输运导致的溢流沉积是其最主要的控制因素。另外,粒度、河流悬浮体的输入沉降和有机质保存条件等因素也起着重要作用。

关键词：孟加拉湾沉积物有机碳粒度 TOC/TN

坚持党对经济工作的集中统一领导——基于马克思主义政党特质的分析

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理论与改革 2025年第1期 42-51页

作者：胡立法扬州大学马克思主义学院

坚持党对经济工作的集中统一领导是党治国理政的重大任务。从理论与实践来看,必须也必然要坚持党对经济工作的集中统一领导。目前有关坚持党对经济工作集中统一领导的学理阐释多从政治与经济矛盾运动、政党与国家之间关系等视角来进行,... 详细信息

坚持党对经济工作的集中统一领导是党治国理政的重大任务。从理论与实践来看,必须也必然要坚持党对经济工作的集中统一领导。目前有关坚持党对经济工作集中统一领导的学理阐释多从政治与经济矛盾运动、政党与国家之间关系等视角来进行,鲜有从中国共产党自身所具有的特质来阐释。严密的组织体系、把控改革的能力以及对执政资源的引导力与协调力,是中国共产党所具有的特质的重要组成部分,它们决定了必须也必然要坚持党对经济工作的集中统一领导。具体来说,党拥有“横向到边、纵向到底”的组织体系,能有效促进经济增长;党拥有有效把控改革进度和节奏的能力,能在经济体制改革不同阶段作出不同的重大决定;党拥有实现对执政资源的引导力与协调力,能有效实施宏观调控和为国家制定中长期规划以及重大经济发展战略提供物质保障。同时,党领导经济工作的实践也进一步证明了,正是上述特质,决定了必须也必然要坚持党对经济工作的集中统一领导。

关键词：党对经济工作的集中统一领导政党特质社会主义市场经济体制改革开放执政党执政资源

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Continuum estimation in low-resolution gamma-ray spectra based on deep learning

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Nuclear Science and Techniques 2025年第2期36卷 5-17页

作者： Ri Zhao li-Ye liu Xin liu Zhao-Xing liu Run-Cheng liang Ren-Jing ling-Hu Jing Zhang fa-Guo Chen China Institute for Radiation Protection Taiyuan 030006China Shanxi Provincial Key Laboratory for Translational Nuclear Medicine and Precision Protection Taiyuan 030006China

In this study,an end-to-end deep learning method is proposed to improve the accuracy of continuum estimation in low-resolution gamma-ray spectra.A novel process for generating the theoretical continuum of a simulated spectrum is established,and a convolutional neural network consisting of 51 layers and more than 105 parameters is constructed to directly predict the entire continuum from the extracted global spectrum *** testing,an in-house NaI-type whole-body counter is used,and 106 training spectrum samples(20%of which are reserved for testing)are generated using Monte Carlo *** addition,the existing fitting,step-type,and peak erosion methods are selected for *** proposed method exhibits excellent performance,as evidenced by its activity error distribution and the smallest mean activity error of 1.5%among the evaluated ***,a validation experiment is performed using a whole-body counter to analyze a human physical phantom containing four *** largest activity error of the proposed method is−5.1%,which is considerably smaller than those of the comparative methods,confirming the test *** multiscale feature extraction and nonlinear relation modeling in the proposed method establish a novel approach for accurate and convenient continuum estimation in a low-resolution gamma-ray ***,the proposed method is promising for accurate quantitative radioactivity analysis in practical applications.

关键词： Gamma-ray spectrum Continuum estimation Deep learning Convolutional neural network End-to-end prediction

Ubiquitination in diabetes and its complications:A perspective from bibliometrics

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World Journal of Diabetes 2025年第1期16卷 187-203页

作者： li-Yuan Xiong Wei Zhao fa-Quan Hu Xue-Mei Zhou Yu-Jiao Zheng College of Traditional Chinese Medicine Anhui University of Chinese MedicineHefei 230012Anhui ProvinceChina

BACKGROUND Diabetes has a substantial impact on public health,highlighting the need for novel ***,an intracellular protein modification process,is emerging as a promising strategy for regulating pathological *** hypothesize that ubiquitination plays a critical role in the development and progression of diabetes and its complications,and that understanding these mechanisms can lead to new therapeutic *** To uncover the research trends and advances in diabetes ubiquitination and its complications,we conducted a bibliometric *** Studies on ubiquitination in diabetes mellitus and its complications were retrieved from the Web of Science Core *** mapping analysis was conducted using the CiteSpace *** We gathered 791 articles published over the past 23 years,focusing on ubiquitination in diabetes and its associated *** articles originated from 54 countries and 386 institutions,with China as the leading *** Jiao Tong University has the highest number of publications in this *** most prominent authors contributing to this research area include Wei-Hua Zhang,with Zhang Y being the most frequently cited ***,The Journal of Biological Chemistry is noted as the most cited in this *** predominant keywords included expression,activation,oxidative stress,phosphorylation,ubiquitination,degradation,and insulin *** The role of ubiquitination in diabetes and its complications,such as diabetic nephropathy and cardiomyopathy,is a key research ***,these areas require further investigations.

关键词： Diabetes mellitus Ubiquitination Bibliometric analysis CiteSpace Research trends