检索结果-南通市图书馆

Science Letters:Determination of benzalkonium chloride in viscous ophthalmic drops of azithromycin by high-performance liquid chromatography

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2009年第12期10卷 877-882页

作者： Yan SHEN sheng-jie XU Shi-chun WANG Jia-sheng tu Department of Pharmaceutics China Pharmaceutical University Nanjing 210009 China Productivity Center of Jiangsu Province Nanjing 210042 China

A high-performance liquid chromatography （HPLC） system was used in the reversed phase mode for the determination ofbenzalkonium chloride （BKC） in azithromycin viscous ophthalmic drops. A Venusil-XBP（L）-C18 （150 mm×4.6 mm, 5 gm） column was used at 50℃. The mobile phase consisted of a mixture of methanol-potassium phosphate （16：5, v/v）. Two sample preparation methods were compared. The results suggested that, compared with an extraction procedure, a deproteinization procedure was much quicker and more convenient. Using the deproteinization procedure for sample preparation, calibration curves were linear in the range 5.0-50μg/ml. The within-day and inter-day coefficients of variation were less than 10%. The average recoveries were determined as 96.70%, 98.52%, and 97.96% at concentrations of 10.0, 30.0, and 50.0 μg/ml, respectively. Variability in precision did not exceed 5%. In conclusion, this HPLC method using a simple sample treatment procedure appears suitable for monitoring BKC content in azithromycin viscous ophthalmic drops.

关键词： Benzalkonium chloride High-performance liquid chromatography Azithromycin Viscous ophthalmic drops

Soil profile characteristics of high-productivity alluvial cambisols in the North China Plain

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2015年第4期14卷 765-773页

作者： LIU Hai-tao LI Bao-guo REN tu-sheng College of Resources and Environmental Sciences China Agricultural University

The North China Plain（NCP） is one of major breadbaskets in China. Crop growth and grain yield differ significantly with spatial variations of soil properties. This study aims to identify the key soil properties in relation to the grain yield for the winter wheat（Triticum aestivum L.）-maize（Zea mays L.） cropping system in a high-productivity farmland of the NCP. The field trials were conducted in three fields with different grain yield levels in Tai＇an City, Shandong Province, China, during the 2009–2012 period. Consistent field management strategies were applied in the three fields. Fifty-one physical and chemical indicators of the soil profile as related to grain yield were evaluated. An approximate maximum of 17.8% annual average grain yield difference was observed in the fields during the period of 2009–2012. The soil indicators were classified into three clusters with specific functions using cluster analysis, and three key indicators were extracted from each cluster to characterize the different soil properties of three fields. The first cluster represented soil water retention capacity, and the key indicator was available soil water（ASW）, which ranged from 153 to 187 mm in the 1.2 m profile and was correlated positively with grain yield. The second cluster represented soil water conductivity, as measured by saturated hydraulic conductivity（K s）. The higher yield field had a greater capacity to retain topsoil water for its lower K s（1.9 cm d^–1） in the 30–70 cm soil layer as compared to the lower yield field. The third cluster represented nutrient storage and supply, as indicated by the ratio of nutrient content to silt＋clay content of the top soil layer. The ratio of soil organic matter（OM）, total nitrogen（TN）, available P, exchangeable K＋ to silt＋clay content in the 0–20 cm soil layer were 19.0 g kg^–1, 1.6 g kg^–1, 94.7 mg kg^–1, 174.3 mg kg^–1 in the higher yield field, respectively, and correlated positively with the grain yield. By characterizing the diff

关键词： soil quality assessment cluster analysis grain yield key soil indicators

Soil Aggregate Stability and Aggregate-Associated Carbon Under Different Tillage Systems in the North China Plain

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2013年第11期12卷 2114-2123页

作者： DU Zhang-liu REN tu-sheng HU Chun-sheng ZHANG Qing-zhong Humberto Blanco-Canqui Institute of Environment and Sustainable Development in Agriculture Chinese Academy of Agricultural Sciences College of Resources and Environmental Sciences China Agricultural University Center for Agricultural Resources Research Institute of Genetics and Development BiologyChinese Academy of Sciences Agricultural Research Center-Hays Kansas State University

The inlfuences of tillage systems on soil carbon （C） stocks have been studied extensively, but the distribution of soil C within aggregate fractions is not well understood. The objective of this study was to determine the inlfuences of various tillage systems on soil aggregation and aggregate-associated C under wheat （Triticum aestivum L.） and corn （Zea mays L.） double cropping systems in the North China Plain. The experiment was established in 2001, including four treatments：moldboard plow （MP） with residue （MP＋R） and without residue （MP-R）, rotary tillage with residue （RT）, and no-till with residue （NT）. In 2007 soil samples were collected from the 0-5, 5-10, and 10-20 cm depths, and were separated into four aggregate-size classes （〉2 000, 250-2 000, 53-250, and〈53 μm） by wet-sieving method. Aggregate-associated C was determined, and the relationships between total soil C concentration and aggregation-size fractions were examined. The results showed that NT and RT treatments signiifcantly increased the proportion of macroaggregate fractions （〉2 000 and 250-2 000 μm） compared with the MP-R and MP＋R treatments. Averaged across all depths, mean weight diameters of aggregates （MWD） in NT and RT were 47 and 20% higher than that in MP＋R. The concentration of bulk soil organic C was positively correlated with MWD （r=0.98; P=0.024） and macroaggregate fraction （r=0.96; P=0.036） in the 0-5 cm depth. In the 0-20 cm depth, comparing with MP＋R, total C occluded in the〉2 000 μm fraction was increased by 9 and 6%under NT and RT, respectively. We conclude that adoption of conservation tillage system, especially no-till, can increase soil macro-aggregation and total C accumulation in macroaggregates, which may improve soil C sequestration in the intensive agricultural region of the North China Plain.

关键词： tillage systems aggregate stability aggregate-associated C

Synthesis and Crystal Structure of 4-(4-Bromophenyl)- 3,4-dihydro-6-methyl quinolin-2(1H)-one

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Structural Chemistry 2007年第5期26卷 533-536页

作者： YU Chen-Xia ZHU Xiao-Tong YAO Chang-sheng tu Shu-Jiang Department of Chemistry Xuzhou Normal University Xuzhou 221116 China Key Laboratory of Biotechnology for Medical Plants of Jiangsu Province Xuzhou 221116 China

The title compound （C16H14BrNO） has been synthesized by the reaction of p-tolylamine, Meldrum’s acid and 4-bromo-benzaldehyde, and its structure was characterized by IR, 1H NMR and X-ray single-crystal diffraction. The crystal belongs to monoclinic, space group P21/n with a = 7.6850（11）, b = 8.3004（11）, c = 21.301（3）A, β = 95.110（2）°, V = 1353.4（3） A^3, Mr = 316.19, Z = 4, Dc = 1.552 g/cm^3, μ（MoKα） = 3.028 mm-1, F（000） = 640, the final R = 0.0345 and wR = 0.0768. X-ray analysis reveals that the atoms of C（1）, C（2）, C（3）, C（4）, C（5） and N（1） form a six-membered ring of boat conformation.

关键词： quinoline crystal structure

针对性干预对阿替普酶溶栓治疗急性缺血性脑卒中后认知功能的影响

在线全文

学校读者我要写书评

暂无评论

血管与腔内血管外科杂志 2024年第7期10卷 866-870页

作者：李馨颖王钰李贯清涂胜亳州市人民医院神经内科安徽亳州236800 亳州市人民医院介入科安徽亳州236800 亳州市人民医院心内科安徽亳州236800

目的探讨针对性干预对阿替普酶溶栓治疗急性缺血性脑卒中后认知功能的影响。方法收集2020年1月至2023年6月亳州市人民医院收治的92例急性缺血性脑卒中患者的临床资料,根据住院期间是否接受了针对性干预将患者分为观察组(n=48)和对照组(n... 详细信息

目的探讨针对性干预对阿替普酶溶栓治疗急性缺血性脑卒中后认知功能的影响。方法收集2020年1月至2023年6月亳州市人民医院收治的92例急性缺血性脑卒中患者的临床资料,根据住院期间是否接受了针对性干预将患者分为观察组(n=48)和对照组(n=44)。所有患者均成功接受了阿替普酶静脉溶栓治疗。比较两组患者的急性缺血性脑卒中病情、治疗情况、治疗前后认知功能及住院期间并发症发生情况。结果两组患者发病至溶栓的时间、卒中部位、美国国立卫生研究院卒中量表(NIHSS)评分、缺血灶最大直径及阿替普酶总剂量比较,差异均无统计学意义(P﹥0.05)。治疗后,两组患者蒙特利尔认知功能评估(MoCA)量表中各维度评分均高于本组治疗前,且观察组患者MoCA量表中各维度评分均高于对照组患者,差异均有统计学意义(P﹤0.05)。两组患者住院期间并发症的发生率比较,差异无统计学意义(P﹥0.05)。结论针对性干预可以进一步改善阿替普酶溶栓治疗急性缺血性脑卒中后患者的认知功能,并具有较好的安全性,值得临床推广。

关键词：针对性干预阿替普酶溶栓急性缺血性脑卒中认知功能

新工科背景下材料专业实践教学体系建设路径探索

在线全文

学校读者我要写书评

暂无评论

教育教学论坛 2024年第16期 121-124页

作者：贺图升黎载波刘洋田长安韶关学院化学与土木工程学院广东韶关512005

新工科作为一种全新的教育理念,不仅要求大学生具备过硬的专业技术,还要具有创新精神、实践能力和工程素养,因此,高校要注重大学生的思想政治教育,而实践教学是实现这一目标的重要途径之一。针对目前专业实践教学体系建设存在的不足,结... 详细信息

新工科作为一种全新的教育理念,不仅要求大学生具备过硬的专业技术,还要具有创新精神、实践能力和工程素养,因此,高校要注重大学生的思想政治教育,而实践教学是实现这一目标的重要途径之一。针对目前专业实践教学体系建设存在的不足,结合应用型地方高校材料专业自身发展现状以及新工科教育理念,从实践教学中的基地建设、方案建设、思政建设、考评制度建设、师资队伍建设等方面提出了相应举措,以期为地方应用型高校实践教学改革提供参考与借鉴。

关键词：实践教学课程思政新工科

在线全文

学校读者我要写书评

暂无评论

以继发性高血压为首要表现的肢端肥大症1例

临床心血管病杂志 2024年第8期40卷 692-694页

作者：李东戈江荣炎涂胜卜令同亳州市人民医院心内科安徽亳州236800

肢端肥大症是一种起病隐匿的慢性进展性内分泌疾病,可并发各种严重的心血管疾病。我科收治1例以继发性高血压为首要表现的肢端肥大症患者,现报告如下。

关键词：继发性高血压肢端肥大症

血清脂蛋白a水平与二尖瓣环钙化的相关性分析

在线全文

学校读者我要写书评

暂无评论

中华全科医学 2024年第10期22卷 1700-1704页

作者：潘路华朱明利陈多学涂胜亳州市人民医院心内科

目的研究血清脂蛋白a[Lp(a)]与二尖瓣环钙化及其二尖瓣功能障碍之间的潜在联系。方法收集2022年1月—2023年11月于亳州市人民医院心血管内科住院并行冠脉CT血管成像(CTA)患者的临床资料，共131例，根据图像分析，分为二尖瓣环钙化(MAC... 详细信息

目的研究血清脂蛋白a[Lp(a)]与二尖瓣环钙化及其二尖瓣功能障碍之间的潜在联系。方法收集2022年1月—2023年11月于亳州市人民医院心血管内科住院并行冠脉CT血管成像(CTA)患者的临床资料，共131例，根据图像分析，分为二尖瓣环钙化(MAC)组(62例)及正常组(69例)。收集患者基线资料包括年龄、性别、高血压、糖尿病、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白A、载脂蛋白B、血清脂蛋白a、肌酐、尿酸、同型半胱氨酸、服用他汀史等。比较2组临床基本资料及发生二尖瓣狭窄及反流的差异，分析MAC的危险因素及MAC引起的相关二尖瓣疾病的风险。结果二尖瓣环钙化组及正常组的LDL-C、Lp(a)差异有统计学意义(P<0.001)。Logistic回归分析显示Lp(a)升高是MAC的独立危险因素(OR=1.256,95%CI:1.002～1.490,P=0.008)。重度MAC组与正常组、轻度MAC组、中度MAC组患者的Lp(a)水平差异均有统计学意义(P<0.05)。MAC组及正常组二尖瓣狭窄发生率差异无统计学意义[8.06%(5/62)vs. 1.45%(1/69),P=0.165],但MAC组比正常组二尖瓣反流发生率高[17.74%(11/62)vs. 4.35%(3/69),P=0.013]。结论 Lp(a)水平升高是二尖瓣环钙化的危险因素之一，MAC可能增加二尖瓣反流风险，建议对MAC患者应注意监测Lp(a)并加强控制Lp(a)水平，控制Lp(a)水平可能对预防二尖瓣环钙化及其相关二尖瓣疾病的发生具有潜在意义。

关键词：血清脂蛋白a 二尖瓣环钙化二尖瓣反流

Effect of final electromagnetic stirring on solidification microstructure of GCr15 bearing steel in simulated continuous casting

在线全文

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2020年第2期27卷 141-147页

作者： Dan-qing Jiang Rui Wang Qiong Zhang Zhen-qiang Zhang Ting-sheng tu Jiang Wang Zhong-ming Ren School of Materials Science and Engineering Shanghai UniversityShanghai 200444China State Key Laboratory of Advanced Special Steel Shanghai UniversityShanghai 200444China

The effect of final electromagnetic stirring on the solidification structure,element segregation,and carbides of GCrl5 bearing steel was *** experiment of continuous casting of the steel was carried out by using a continuous casting physical simulation apparatus with the final electromagnetic *** liquid core profile was revealed by the pour-out method during the solidification *** ingots were produced under different electromagnetic stirring parameters for *** results show that,at the final stage of solidification,intense electromagnetic stirring exacerbates the central carbon segregation,resulting in more serious precipitation of the primary *** is also found that the carbides in the segregation area are dominantly M3C type,together with a small amount of M7C3-type and M3C2-type *** this physical simulation model,the optimal stirring parameters to obtain a fine and homogeneous structure are the liquid pool width of 15 mm,current intensity of 150 A,and stirring frequency of 5 Hz.

关键词： GCrl5 bearing steel Solidification structure Continuous casting Final electromagnetic stirring Segregation Carbide