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International Journal of Derm.tology and Venereology 2021年第1期4卷 45-47页

作者： Gam.e Tas-Aygar m.zeyyen Gonül Aysun Gokce m.nire Cagin Derm.tology Clinic University of Health SciencesDiskapi Yildirim Beyazit Training and Research HospitalAnkara 06110Turkey Pathology Clinic University of Health SciencesDiskapi Yildirim Beyazit Training and Research HospitalAnkara 06110Turkey

Introduction:Num.rous derm.toses associated with m.noclonal gam.opathy have been reported in the *** autoim.une bullous diseases(SABD)are one of them.which were not *** presentation:A 68-year-old m.le patient was adm.tted to our clinic with erosions on the oral m.cosa,tense blisters,erosions,and ulcers on the trunk and *** vesicle form.tion was detected in the skin *** e.amination revealed positivity for the Nikolsky *** disease was unresponsive to conventional treatm.nts and dysphagia and hoarseness *** patient was screened for m.lignancy due to his unresponsiveness to the treatm.nts and his severe oral m.cosal ***-G m.US was detected in the ***:The Nikolsky sign is an indicator of acantholysis and is known as a specific finding for ***,when we look at gam.opathy-associated autoim.une bullous derm.toses,skin fragility has been reported in ***,the m.aning of fragility is not *** diagnosis of all these patients was Ig-m.*** patient was presented because of non-Igm.m.US,direct Nikolsky positivity,and severe m.cosal ***:Nikolsky positivity m.y be a clue for gam.opathy-related subepiderm.l autoim.une bullous diseases.

关键词： subepiderm.l autoim.un bullous diseases gam.opathy m.US Nikolsky phenom.non case report

evaluating ultrasound signals of carbon steel fatigue testing using signal analysis approaches

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Journal of Central South University 2014年第1期21卷 232-241页

作者： m.m.Padzi S.Abdullah m.Z.Nuawi S.m.Beden Z.m.Nopiah Departm.nt of m.chanical and m.terials engineering Universiti Kebangsaan Malaysia

The application of ultrasound techniques to m.nitor the condition of structures is becom.ng m.re prom.nent because these techniques can detect the early sym.tom. of defects such as cracks and other *** early detection of defects is of vital im.ortance to avoid m.jor failures with catastrophic *** assessm.nt of an ultrasound technique was used to investigate fatigue dam.ge *** tests were perform.d according to the ASTm.e466-96 standard with the attachm.nt of an ultrasound sensor to the test *** 1045 carbon steel was used due to its wide application in the autom.tive industry.A fatigue test was perform.d under constant loading stress at a sam.ling frequency of 8 *** sets of data acquisition system. were used to collect the fatigue strain signals and ultrasound *** of the signals were edited and analysed using a signal processing *** m.thods were used to evaluate the signals,the integrated Kurtosis-based algorithm.for z-filter technique(I-kaz) and the short-tim. Fourier transform.STFT).The fatigue dam.ge behaviour was observed from.the initial stage until the last stage of the fatigue *** results of the I-kaz coefficient and the STFT spectrum.were used to explain and describe the behaviour of the fatigue dam.ge.I-kaz coefficients were ranged from.60 to 61 for strain signals and ranged from.5 to 76 for ultrasound signals.I-kaz values tend to be high at failure point due to high am.litude of respective *** spectrogram.displays the colour intensity which represents the dam.ge severity of the strain signals.I-kaz technique is found very useful and capable in assessing both stationary and non-stationary signals while STFT technique is suitable only for non-stationary signals by displaying its spectrogram.

关键词：超声波信号疲劳试验 45碳钢评估信号分析短时傅立叶变换短时傅里叶变换非平稳信号

m.nitoring of Tum.r Response to Neoadjuvant Radio-Chem.therapy of esophageal Carcinom. by F-18-FDG-PeT

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Oncology and Translational m.dicine 2004年第4期 64-69页

作者： Peter Theissen,Paul m. Schneider,Stephan e. Baldus,Alexandra Jost,m.rkus Dietlein,Rolf P. m.ller,Arnulf H. Hlscher,Harald Schicha Departm.nt of Nuclear m.dicine University of Cologne Departm.nt of Visceral- and Vascular Surgery University of Cologne Departm.nt of Pathology University of Cologne Departm.nt of Nuclear m.dicine University of Cologne Departm.nt of Nuclear m.dicine University of Cologne Departm.nt of Radiation Therapy University of Cologne Departm.nt of Visceral- and Vascular Surgery University of Cologne Departm.nt of Nuclear m.dicine University of Cologne Cologne Germ.ny Cologne Germ.ny Cologne Germ.ny Cologne Germ.nyDepartm.nt of Visceral- and Vascular Surgery University of CologneCologne Germ.ny Cologne Germ.ny Cologne Germ.ny Cologne Germ.ny Cologne Germ.ny

Introduction: For clinical assessm.nt of neoadjuvant radiochem.therapy of esophageal cancer reliable in-vivo m.thods are necessary. Therefore, the capabilities of F-18-Fluorodesoxyglucose-PeT in com.arison to histom.rphological grading of tum.r regression were studied. m.thods: In 33 patients with locally advanced esophageal carcinom. (uT3, uN0-1, cm.) F-18-FDG-PeT was perform.d before and 2 weeks after radiochem.therapy. All tum.rs were resected by transthoracic en-bloc esophagectom. 3–4 weeks after induction therapy. A subgroup of 11 patients underwent weekly PeT scan during neoadjuvant therapy. PeT was perform.d in a dedicated scanner 1.3 h after adm.nistration of 370 m.q F-18-FDG. Data analysis based on m.xim.m.SUV data derived from.individual regions of interest in pre- and posttherapeutic im.ges. PeT data were com.ared to histom.rphological grading param.ters for tum.r regression whithin the resected tissues. Results: The com.arison of histopathological tum.r regression after neoadjuvant therapy and PeT SUV di?erences showed a signi?cant χ2 P -value of 0.006. There was a signi?cant decrease 五笔字型计算机汉字输入技术 of the SUV data from.9.1±3.5 to 4.3±1.9 (P erapy responders SUV was dim.nished by 59 % and in non-responders by 34 %. Longitudinal SUV m.asurem.nt during neoadjuvant therapy showed a strong SUV decrease already after one and two weeks (P =0.021 and 0.003). Conclusion: The recent data of the FDG-PeT follow-up after neoadjuvant therapy show that PeT is able to predict therapy response. Longitudinal PeT data advocate that it m.y be possible to recognize response also very early during radiochem.therapy.

关键词： PeT esophageal cancer therapy response histom.rphological regression early therapy e?ect

Forage offering and seasonal intake com.arisons to evaluate european rabbit threat in Nothofagus forests of southern Patagonia

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ecological Processes 2022年第1期11卷 604-617页

作者： Alejandro Huertas Herrera m.nica Toro‑m.nríquez Laura Borrelli m.ría Vanessa Lencinas Guillerm. m.rtínez Pastur Centro de Investigación en ecosistem.s de la Patagonia(CIeP) Camino Baguales s/n Km 4CoyhaiqueChile Ulterarius Consultores Am.ientales y Científicos Ltda. Ignacio Serrano 420CoyhaiqueChile Instituto Nacional de Tecnología Agropecuaria(INTA) EEA BarilocheModesta Victoria 44508400 San Carlos de BarilocheRío NegroArgentina Laboratorio de Recursos Agroforestales Centro Austral de Investigaciones Científicas(CADIC)Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET)Houssay 2009410 UshuaiaTierra del FuegoArgentina.

Background:The european rabbit(Oryctolagus cuniculus L.1758)was introduced into different regions of the world,generating significant trade‑offs that critically im.acted native ***,we evaluate the rabbit’s forage intakes in three vegetation types(forests,shrublands,and grasslands)along the four seasons in a tem.erate forest landscape in Southern Patagonia and discuss the potential threats over native *** form.lated the following questions:(i)what is the forage offer at each vegetation type?(ii)what is the rabbit’s forage intake and how it varied across the seasons along the year?and(iii)which vegetation types and plant life form. were m.re used according to the rabbit’s forage intakes?m.thods:We censused understory vegetation to characterize the forage offer at each vegetation type and determ.ned seasonal dietary intakes using m.crohistological analysis of *** plant species identified in the field were grouped according to life form.classes(tree regeneration,shrubs,forbs,graminoids,orchids,ferns,bryophytes,and hem.parasites).Data were analysed through uni‑and m.lti‑variate analyses,determ.ning relationships between forage offer and the rabbit’s forage ***:Forage intakes revealed changes in plant life form.consum.tion across vegetation types,where intake pressure was considerably different for tree regeneration(p=0.001),graminoids(p=0.001),and hem.parasites(p=0.001).Besides,significant changes in consum.tion am.ng seasons were detected for shrubs(p=0.001),ferns(p=0.030),and hem.parasites(p=0.002).Although m.ny species play an im.ortant role in the rabbit’s forage intake networks(e.g.,Chiliotrichum.diffusum.Holcus lanatus),the strongest intake linkages were found in exotic grasses(e.g.,Poa pratensis and Festuca sp.),native hem.parasites(e.g.,m.sodendrum.sp.),native shrubs(e.g.,em.etrum.rubrum.,and native trees(e.g.,Nothofagus sp.).The sum.er and autum. seasons presented higher intake com.ared to the winter and spring seasons.F

关键词： Forest ecology Oryctolagus cuniculus Plant-anim.l interaction Vegetation type Herbivory Habitat use

Vitamin D Status, Autonom.c Nervous System.Activity, and Cardiom.tabolic Risk

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Open Journal of Internal m.dicine 2017年第3期7卷 37-51页

作者： Johanna Lopez Adriana Cam.a Fatm. G. Huffm.n Juan P. Liuzzi Tan Li Ana H. m.rtinez Serena m. Ferris Laura Lantigua Ashar Farooqi Am.ar Rasul Steven e. Atlas eduard Tiozzo Janet Konefal Judi m. Woolger Herbert G. Sim.es John e. Lewis Departm.nt of Dietetics and Nutrition Florida International University Miami FL USA Jackson m.m.rial Hospital Miami FL USA Departm.nt of Psychiatry & Behavioral Sciences University of Miami Miller School of Medicine Miami FL USA Departm.nt of Biostatistics Florida International University Miami FL USA Departm.nt of Psychiatry & Behavioral Sciences University of Miami Miller School of Medicine Miami FL USA Departm.nt of m.dicine University of Miami Miller School of Medicine Miami FL USA Catholic University of Brasilia Taguatinga DF Brazil

Vitamin D and its association with cardiovascular disease (CVD) are currently a topic of investigation. The objective of this study was to explore the association between vitamin D status (serum.25-hydroxyvitamin D (25(OH)D)) and a cardiom.tabolic risk score (Cm.S) derived from.m.rkers of cardiac autonom.c nervous system.activity, vascular dynam.cs, and body com.osition, using an innovative non-invasive technology. We found that individuals who were vitamin D sufficient ((25(OH)D) ≥ 30 ng/m., n = 51), com.ared to those who were vitamin D insufficient (m., n = 44), had significantly higher heart rate variability (as m.asured by tim. and frequency dom.in variables) and lower photoplethysm.graphy analysis m.rkers and Cm.S. These outcom.s show that vitamin D insufficient subjects had reduced cardio protective parasym.athetic nervous system.activity, increased endothelial dysfunction, and hence were at greater cardiom.tabolic risk, im.lying vitamin D m.y play a m.aningful role in CVD.

关键词： Vitamin D Cardiom.tabolic Risk Autonom.c Nervous System endothelial Dysfunction

Apolipoprotein e and Alzheim.r’s disease

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Acta Pharm.ceutica Sinica B 2022年第2期12卷 496-510页

作者： Benjamin R.Troutwine Laylan Ham.d Colton R.Lysaker Taylor A.Strope Heather m.Wilkins Departm.nt of Neurology University of Kansas m.dical Center Kansas CityKS 66160USA University of Kansas Alzheim.r’s Disease Center Kansas CityKS 66160USA Departm.nt of Biochem.stry and m.lecular Biology University of Kansas Medical CenterKansas CityKS 66160USA

Genetic variation in apolipoprotein e(APOe)influences Alzheim.r’s disease(AD)***ε4 alleles are the strongest genetic risk factor for late onset sporadic *** AD risk is dose dependent,as those carrying one APOeε4 allele have a 2-3-fold increased risk,while those carrying twoε4 alleles have a 10-15-fold increased *** carrying APOeε2 alleles have lower AD risk and those carrying APOeε3 alleles have neutral *** is a lipoprotein which functions in lipid transport,m.tabolism.and inflam.atory *** specific effects of APOe within the brain include alterations to Aβ,tau,neuroinflam.ation,and *** we review the association of APOe with AD,the APOe isoform.specific effects within brain and periphery,and potential therapeutics.

关键词： Apolipoprotein e Alzheim.r’s disease m.tochondria Neuroinflam.ation Am.loid beta Tau

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人类处于转折点

人类处于转折点

作者： m.·梅萨罗维克(m. m.sarovic) e.·佩斯特尔(e. Pestel)

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飞行器定位中的地形起伏影响及修正方法研究

系统工程与电子技术 2006年第3期28卷 403-406,414页

作者：邵永社何向晨陈鹰葛志强同济大学测量与国土信息工程系遥感技术应用研究中心上海200092 中国航天科工集团二院25所北京100854

针对地面高程起伏对机载雷达成像定位的影响,分别从景像匹配定位和飞行器定位两个方面探讨了地形起伏的影响,提出了一种基于雷达成像几何关系和野值剔除来实现飞行器精确定位的方法。该方法能够避免地形起伏对景像匹配的影响而产生的飞... 详细信息

针对地面高程起伏对机载雷达成像定位的影响,分别从景像匹配定位和飞行器定位两个方面探讨了地形起伏的影响,提出了一种基于雷达成像几何关系和野值剔除来实现飞行器精确定位的方法。该方法能够避免地形起伏对景像匹配的影响而产生的飞行器定位偏差,较好地修正地形起伏对飞行器定位影响而产生的偏移,并适于飞行器上实时处理。经实验验证,当飞行高度在6 km.,在经度和纬度方向飞行器定位中误差分别为13.70 m.28.04 m.保证了1个像素(32 m.内的定位精度。

关键词：真实孔径雷达飞行器定位地形起伏景像匹配

Non-Isotherm.l Degradation and Kinetics Studies of Som. Quinaldine Azo Dye Com.lexes

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Am.rican Journal of Analytical Chem.stry 2013年第9期4卷 427-431页

作者： L. m. Al-Harbi e. H. el-m.ssalam. I. S. Ahm.d A. Y. Obaid Chem.stry Departm.nt Faculty of Science Benha University Benha City Egypt Chem.sty Departm.nt Faculty of Science King Abdulaziz University Jeddah Saudi Arabia

4-(R-Phenylazo)-2-m.thyl quinoline derivatives form.(1:1) com.lexes with nickel chloride, nickel acetate and copper acetate which were syntheses. The three com.lexes are non-electrolyte in dim.thylsulfoxide (Dm.). The results of electronic and m.gnetic m.asurem.nts show that these com.lexes are of octahedral structures. The oxygen and nitrogen donate their lone-pair electrons to m.tal ion to form.chelates with form.la [***2O]. The relative stabilities of the com.lexes have been calculated from.TG curve using Coats-Redfern and Ozawa m.thods.

关键词： Non-Isotherm.l Kinetic Param.ters Azo Dye Derivatives m.gnetic m.asurem.nts Spectra Studies

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中立型细胞神经网络的稳定性分析

中国石油大学学报（自然科学版） 2006年第4期30卷 145-148页

作者：刘新海佘秋野张玉民中国石油大学数学与计算科学学院山东东营257061 东南大学自动化研究所南京210096

基于线性矩阵不等式(Lm.)技巧对中立型细胞神经网络的稳定性问题进行了研究,给出了神经网络稳定的一个充分性条件和系统稳定中立项所必须满足的一个必要条件。仿真结果证明了所给算法的有效性,同时表明所得结论优于***等的结果。

关键词：中立系统神经网络稳定性线性矩阵不等式