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Fortifying Healthcare Data Security in the Cloud:A Comprehensive Examination of the EPM-KEA Encryption Protocol

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Computers, Materials & Continua 2024年第5期79卷 3397-3416页

作者： Umi Salma Basha shashi kant Gupta Wedad Alawad SeongKi Kim Salil Bharany Computer Science and Information Technology Jazan UniversityJazanSaudi Arabia CSE Eudoxia Research UniversityNew CastleUSA Department of Information Technology College of Computer ScienceQassim UniversityBuraydahSaudi Arabia National Center of Excellence in Software Sangmyung UniversitySeoulKorea Department of Computer Science and Engineering Lovely Professional UniversityPhagwaraPunjabIndia

A new era of data access and management has begun with the use of cloud computing in the healthcare *** the efficiency and scalability that the cloud provides, the security of private patient data is still a majorconcern. Encryption, network security, and adherence to data protection laws are key to ensuring the confidentialityand integrity of healthcare data in the cloud. The computational overhead of encryption technologies could leadto delays in data access and processing rates. To address these challenges, we introduced the Enhanced ParallelMulti-Key Encryption Algorithm (EPM-KEA), aiming to bolster healthcare data security and facilitate the securestorage of critical patient records in the cloud. The data was gathered from two categories Authorization forHospital Admission (AIH) and Authorization for High Complexity *** use Z-score normalization forpreprocessing. The primary goal of implementing encryption techniques is to secure and store massive amountsof data on the cloud. It is feasible that cloud storage alternatives for protecting healthcare data will become morewidely available if security issues can be successfully fixed. As a result of our analysis using specific parametersincluding Execution time (42%), Encryption time (45%), Decryption time (40%), Security level (97%), and Energyconsumption (53%), the system demonstrated favorable performance when compared to the traditional *** suggests that by addressing these security concerns, there is the potential for broader accessibility to cloudstorage solutions for safeguarding healthcare data.

关键词： Cloud computing healthcare data security enhanced parallel multi-key encryption algorithm(EPM-KEA)

Optimality Conditions and Duality for Nondifferentiable Multiobjective Semi-Infinite Programming Problems with Generalized(C,α,ρ,d)-Convexity

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Journal of Systems Science & Complexity 2015年第1期28卷 47-59页

作者： MISHRA shashi kant JAISWAL Monika HOAI AN Le Thi Department of Mathematics Banaras Hindu University Laboratory of Theoretical and Applied Computer Science LITA UFR MIMUniversity of Lorraine

This paper obtains sufficient optimality conditions for a nonlinear nondifferentiable multiobjective semi-infinite programming problem involving generalized(C,α,ρ,d)-convex *** authors formulate Mond-Weir-type dual model for the nonlinear nondifferentiable multiobjective semiinfinite programming problem and establish weak,strong and strict converse duality theorems relating the primal and the dual problems.

关键词： Duality generalized convexity optimality conditions semi-infinite programming.

ON APPROXIMATE EFFICIENCY FOR NONSMOOTH ROBUST VECTOR OPTIMIZATION PROBLEMS

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Acta Mathematica Scientia 2020年第3期40卷 887-902页

作者： Tadeusz ANTCZAK Yogendra PANDEY Vinay SINGH shashi kant MISHRA Faculty of Mathematics and Computer Science University of LódźBanacha 2290-238 LódźPoland Department of Mathematics Satish Chandra CollegeBallia 277001India Department of Mathematics National Institute of TechnologyAizawl-796012MizoramIndia Department of Mathematics Banaras Hindu UniversityVaranasi-221005India

In this article,we use the robust optimization approach(also called the worst-case approach)for findingε-efficient solutions of the robust multiobjective optimization problem defined as a robust(worst-case)counterpart for the considered nonsmooth multiobjective programming problem with the uncertainty in both the objective and constraint ***,we establish both necessary and sufficient optimality conditions for a feasible solution to be anε-efficient solution(an approximate efficient solution)of the considered robust multiobjective optimization *** also use a scalarizing method in proving these optimality conditions.

关键词： Robust optimization approach robust multiobjective optimization ε-efficient solution ε-optimality conditions scalarization

On Semi-infinite Mathematical Programming Problems with Equilibrium Constraints Using Generalized Convexity

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Journal of the Operations Research Society of China 2020年第4期8卷 619-636页

作者： Bhuwan Chandra Joshi shashi kant Mishra Pankaj Kumar Centre for Interdisciplinary Mathematical Sciences Department of Science&TechnologyInstitute of ScienceBanaras Hindu UniversityVaranasi 221005India Department of Mathematics Institute of ScienceBanaras Hindu UniversityVaranasi 221005India Mahila Maha Vidyalaya Banaras Hindu UniversityVaranasi 221005India

In this paper,we consider semi-infinite mathematical programming problems with equilibrium constraints(SIMPPEC).By using the notion of convexificators,we establish sufficient optimality conditions for the *** formulate Wolfe and Mond–Weir-type dual models for the SIMPPEC under the invexity and generalized invexity *** and strong duality theorems are established to relate the SIMPPEC and two dual programs in the framework of convexificators.

关键词： Duality Convexificators Generalized invexity Constraint qualification

Intracranial pressure monitoring:Gold standard and recent innovations

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World Journal of Clinical Cases 2019年第13期7卷 1535-1553页

作者： Deb Sanjay Nag Seelora Sahu Amlan Swain shashi kant Department of Anaesthesiology and Critical Care Tata Main Hospital

Intracranial pressure monitoring (ICP) is based on the doctrine proposed by Monroe and Kellie centuries ago. With the advancement of technology and science, various invasive and non-invasive modalities of monitoring ICP continue to be developed. An ideal monitor to track ICP should be easy to use, accurate, reliable, reproducible, inexpensive and should not be associated with infection or haemorrhagic complications. Although the transducers connected to the extra ventricular drainage continue to be Gold Standard, its association with the likelihood of infection and haemorrhage have led to the search for alternate noninvasive methods of monitoring ICP. While Camino transducers, Strain gauge micro transducer based ICP monitoring devices and the Spiegelberg ICP monitor are the emerging technology in invasive ICP monitoring, optic nerve sheath diameter measurement, venous opthalmodynamometry, tympanic membrane displacement, tissue resonance analysis, tonometry, acoustoelasticity, distortionproduct oto-acoustic emissions, trans cranial doppler, electro encephalogram, near infra-red spectroscopy, pupillometry, anterior fontanelle pressure monitoring, skull elasticity, jugular bulb monitoring, visual evoked response and radiological based assessment of ICP are the non-invasive methods which are assessed against the gold standard.

关键词： Intracranial pressure increase Craniocerebral trauma Subarachnoid hemorrhages

Dynamic hip screw with locking side plate： a viable treatment option for intertrochanteric fracture

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Chinese Journal of Traumatology 2014年第2期17卷 88-92页

作者： Nilesh Barwar Sanjay Meena shashi kant Aggarwal Prashant Garhwal Department of Orthopedics All India Institute ofMedical Sciences New Delhi 110029 India Department of Orthopaedics SP Medical College andAssociated Group of Hospitals Bikaner Rajasthan India

Objective： Dynamic hip screw （DHS） is recommended for the fixation of stable intertrochanteric fractures. Its postoperative cut-out rate ranges from I% to 6%. In osteoporotic bone, normal screws in DHS blade provide less anchorage compared to locking screws. This study aims to compare DHS with locking side plate and conventional side plate. Methods： Fifty consecutive patients with intertrochanteric fractures were randomly allocated for fixation with a standard DHS （group A） and locking DHS （Combi plate, group B）. We compared the clinical and radiological outcomes for the conventional DHS and locking DHS in intertrochanteric fractures. Functional outcome was evaluated using the Parker mobility score. Results： Coxa valga was found more frequently in group A than in group B （12% vs. 0%, P=0.42）. Coxa vara showed the same trend （12% vs. 8%, P=0.81）. Rate of restoration of postoperative neck-shaft angle within 20° of sound side was higher in group B （8% cases） than in group A （4% cases, P=0.98）. The rate of anteversion angle restoration within 10° of sound side was also higher in group B （100% vs. 88%, P=0.85）. The average lag screw slippage in group A and group B was 3.2 mm and 4.2 mm, the average fracture union duration was 17.1 weeks and 16.4 weeks, and the mean Parker score was 5.6 and 5.8 respectively. Screw cut-out was seen in one patient in group A. No cut-out was seen in any of the patient in group B. No patient developed deep infection, avascular necrosis, deep vein thrombosis or any other significant complications. Conclusion： The present study demonstrated that treating intertrochanteric fracture with a locking DHS allows sound bone healing and is not associated with any major complications. Although this report is promising, it should be interpreted with caution because only a prospective study with a large sample size would allow definitive conclusion.

关键词： Hip fractures Bone screws Bone plates

Comparative analysis of APACHE-Ⅱ and P-POSSUM scoring systems in predicting postoperative mortality in patients undergoing emergency laparotomy

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World Journal of Clinical Cases 2019年第16期7卷 2227-2237页

作者： Deb Sanjay Nag Ankur Dembla Pratap Rudra Mahanty shashi kant Abhishek Chatterjee Devi Prasad Samaddar Parul Chugh Department of Anaesthesiology and Critical Care Tata Main HospitalJamshedpur 831001India Department of Anaesthesiology and Critical Care Darya Ram HospitalSonipat 131001India Department of Biomedical Statistics Sir Ganga Ram HospitalNew Delhi 110060India

BACKGROUND Laparotomy remains one of the commonest emergency surgical *** prognostic evaluation would aid in selecting the high-risk patients for an aggressive treatment. Awareness about risks could potentially contribute to the quality of perioperative care and optimum utilization of resources. Portsmouth modification of Physiological and operative severity for the enumeration of mortality and morbidity(P-POSSUM) and the acute physiology and chronic health evaluation Ⅱ(APACHE-Ⅱ) have been the most widely used scoring systems for emergency laparotomies. It is always better to have a single scoring system to predict outcomes and audit healthcare *** To compare the ability of APACHE-Ⅱ and P-POSSUM to predict postoperative morbidity and mortality in patients undergoing emergency *** All patients undergoing emergency laparotomy at the Tata Main Hospital,Jamshedpur between December 2013 and November 2014 were included in the study. In this observational study, P-POSSUM and APACHE-Ⅱ scoring were done, and the outcome analysis evaluated with mortality being the primary *** For P-POSSUM, at a cut off value of 63 to predict mortality using receiver operating characteristics curve analysis, the area under the curve was 0.989; and for APACHE-Ⅱ, at the cut off value of 24, the area under the curve was *** Because the ability of APACHE-Ⅱ to predict mortality was similar to P-POSSUM and APACHE-Ⅱ does not need scoring for intra-operative findings and histopathology reports, APACHE-Ⅱ can be used pre-operatively to assess the risk in patients undergoing emergency laparotomy. However, for audit purposes,either of the two scoring systems can be used.

关键词： Laparotomy Emergencies Acute physiology and chronic health evaluation Ⅱ Morbidity Mortality

Synthesis and evaluation of novel analogues of mangiferin as potent antipyretic

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Asian Pacific Journal of Tropical Medicine 2011年第11期4卷 866-869页

作者： shashi kant Singh Saurabh K Sinha SK Prasad R Kumar Bhawani S Bithu S Sadish Kumar P Singh Varanasi College of Pharmacy Uttar PradeshVaranasiIndia Department of Pharmaceutics Institute of TechnologyBanaras Hindu UniversityVaranasiUttar PradeshIndia Institute of Technology and Sciences Paramedical College(Pharmacy)MuradnagarUttar PradeshIndia Uday Pratap College VaranasiUttar PradeshIndia

Objective:To screen different analogues of mangiferin pharmacologically for antipyretic activity. Methods:The naturally occurring xanthone glycoside mangiferin was isolated by column chromatography from the elhanolic extract of stem bark of Mangifera *** was further converted to 5-(N-phenylamino methyleno) mangiferin.5-(N-p-chlorophenylamino methyleno) mangiferin,5-(N-2-methyl phenylamino methyleno) mangiferin.5-(N-p-methoxy phenylamino methyleno) mangiferin.5-(N,N-diphenylamino methyleno) mangiferin,5-(N-α-napthylamino methyleno) mangiferin and 5-(N-4-methyl phenylamino methyleno) mangiferin *** synthesized compounds were further screened for antipyretic activity along with mangiferin at a dose level of 100 and 200 tng/*** and its analogues were characterized by melting point and R_f value determination and through spectral technique like UV,IR,and NMR spectral ***:The antipyretic activity of mangiferin as well as all analogues was found to be more significant in at higher dose ie.200 mg/kg which was depicted thmugh a decrease in rectal temperature up to 3 ***:The antipyretic activity of mangiferin and its analogues may be attributed to inhibition in synthesis of TNF-αand anti-oxidant activity associated with amelioration of inflammatory actions of cytokines.

关键词： Mangifera indica Mangiferin Antipyretic

A Systematic Review to Explore the Factors Related to Parent to Child Transmission of HIV, Survival and Treatment Provision of Children with HIV in India

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World Journal of AIDS 2015年第3期5卷 245-255页

作者： Arvind Kumar Singh Partha Haldar Sanjay Kumar Rai shashi kant Centre for Community Medicine All India Institute of Medical Sciences New Delhi India

Introduction: There are a multitude of factors that impact the transmission of HIV from parent to child and the subsequent survival of infected children. Changing dynamics in HIV transmission have led to an increase in the number of children living with HIV in India. This review synthesizes the evidence related to transmission of HIV to children, survival and treatment provision among children living with HIV. Methods: A systematic search was conducted in MEDLINE, IndMed, Web of Science, Google Scholar and major journals related to HIV/AIDS to identify relevant studies published between 1992 and 2015. Inclusion criteria included studies related to parent to child transmission of HIV, treatment of children living with HIV and survival of children living with HIV. One of the authors reviewed the studies and extracted the data in a pre-coded extraction sheet. Results: Thirty-three studies were included in the review. HIV transmission rate from parent to Child who received nevirapine prophylaxis ranged from 2.1% to 27.3%. Extended dose regimen of nevirapine prophylaxis was found to be more effective than the single dose regimen. Adherence to ART ranged from 65% to 95%. Adherence varied depending upon the level of health care facility. Both social and medical factors were associated with non-adherence. CD 4 count at the time of diagnosis and delayed age at HIV diagnosis were important predictors of survival. Conclusion: Shift in policy to provide option B regimen is yielding better results. If the age at diagnosis could be reduced further, it would increase the survival of children living with HIV. The program needs to increase access to the health care facilities.

关键词： PPTCT1 ART Children India Adherence Prophylaxis