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Changes in a cerebellar peduncle lesion in a patient with Dandy-Walker malformation A diffusion tensor imaging study

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Neural Regeneration Research 2013年第5期8卷 474-478页

作者： ah Young Lee Sung Ho Jang Sang Seok Yeo Ensil Lee Yun Woo Cho Su Min Son Department of Physical Medicine and Rehabilitation College of Medicine Yeungnam University Department of Pediatrics College of Medicine Yeungnam University

We report a patient with severe ataxia due to Dandy-Walker malformation, who showed functional recovery over 10 months corresponding to a change in a cerebellar peduncle lesion. A 20-month-old female patient who was diagnosed with Dandy-Walker syndrome and six age- and sex-matched healthy control subjects were enrolled. The superior cerebellar peduncle, the middle cerebellar peduncle, and the inferior cerebellar peduncle were evaluated using fractional anisotropy and the apparent diffusion coefficient. The patients＇ functional ambulation category was 0 at the initial visit, but improved to 2 at the follow-up evaluation, and Berg＇s balance scale score also improved from 0 to 7. Initial diffusion tensor tractography revealed that the inferior cerebellar peduncle was not detected, that the fractional anisotropy of the superior cerebellar peduncle and middle cerebellar peduncle decreased by two standard deviations below, and that the apparent diffusion coefficient increased by two standard deviations over normal control values. However, on follow-up diffusion tensor tractography, both inferior cerebellar peduncles could be detected, and the fractional anisotropy of superior cerebellar peduncle increased to within two standard deviations of normal controls. The functional improvement in this patient appeared to correspond to changes in these cerebellar peduncles. We believe that evaluating cerebellar peduncles using diffusion tensor imaging is useful in cases when a cerebellar peduncle lesion is suspected.

关键词： neural regeneration neuroimaging Dandy-Walker malformation cerebellar peduncle ataxia cerebral palsy functional ambulation category Berg's balance scale fractional anisotropy apparent diffusion coefficient diffusion tensor tractography diffusion tensor imaging grants-supported paper photographs-containing paper neuroregeneration

Rehabilitation of spinal cord injuries

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World Journal of Orthopedics 2015年第1期6卷 8-16页

作者： Kemal Nas Levent Yazmalar Volkan ?ah Abdulkadir Ayd?n Kadriye ?ne? Department of Physical Medicine and Rehabilitation School of MedicineSakarya University Department of Physical Medicine and Rehabilitation School of MedicineDicle University Department of Phsyical Treatment and Rehabilitation Erzincan University Mengucek Gazi Training and Research Hospital Orthes and Prothes Center Dicle University Istanbul Physical Medicine and Rehabilitation Research and Training Hospital Physical Therapy and Rehabilitation Clinic

Spinal cord injury(SCI) is the injury of the spinal cord from the foramen magnum to the cauda equina whichoccurs as a result of compulsion, incision or contusion. The most common causes of SCI in the world are traffic accidents, gunshot injuries, knife injuries, falls and sports injuries. There is a strong relationship between functional status and whether the injury is complete or not complete, as well as the level of the injury. The results of SCI bring not only damage to independence and physical function, but also include many complications from the injury. Neurogenic bladder and bowel, urinary tract infections, pressure ulcers, orthostatic hypotension, fractures, deep vein thrombosis, spasticity, autonomic dysreflexia, pulmonary and cardiovascular problems, and depressive disorders are frequent complications after SCI. SCI leads to serious disability in the patient resulting in the loss of work, which brings psychosocial and economic problems. The treatment and rehabilitation period is long, expensive and exhausting in SCI. Whether complete or incomplete, SCI rehabilitation is a long process that requires patience and motivation of the patient and relatives. Early rehabilitation is important to prevent joint contractures and the loss of muscle strength, conservation of bone density, and to ensure normal functioning of the respiratory and digestive system. An interdisciplinary approach is essential in rehabilitation in SCI, as in the other types of rehabilitation. The team is led by a physiatrist and consists of the patients' family, physiotherapist, occupational therapist, dietician, psychologist, speech therapist, social worker and other consultant specialists as necessary.

关键词： Spinal cord Injury Tetraplegia Paraplegia Rehabilitation

Correlation of fatty liver and abdominal fat distribution using a simple fat computed tomography protocol

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World Journal of Gastroenterology 2011年第28期17卷 3335-3341页

作者： Seonah Jang Chang Hee Lee Kyung Mook Choi Jongmee Lee Jae Woong Choi Kyeong ah Kim Cheol Min Park Department of Radiology Korea University Guro HospitalKorea University College of Medicine Department of Internal Medicine (Division of Endocrinology and Metabolism) Korea University Guro HospitalKorea University College of Medicine

AIM: To evaluate the relationship between hepatic fat infiltration and abdominal fat volume by using computed tomography (CT).METHODS: Three hundred and six patients who visited our obesity clinic between November 2007 and April 2008 underwent fat protocol CT *** age range of the patients was 19 to 79 years and the mean age was 49 *** male to female ratio was 116:*** and spleen attenuation measurements were taken with three regions of interests (ROIs) from the liver and two ROIs from the *** attenuation indices (HAIs) were measured as follows: (1) hepatic parenchymal attenuation (CTLP);(2) liver to spleen attenuation ratio (LS ratio);and (3) difference between hepatic and splenic attenuation (LSdif).Abdominal fat volume was measured using a 3 mm slice CT scan starting at the level of the umbilicus and was automatically calculated by a *** fat was classified into total fat (TF),visceral fat (VF),and subcutaneous fat (SF).We used a bivariate correlation method to assess the relationship between the three HAIs and TF,VF,and ***: There were significant negative correlations between CTLP,LS ratio,and LSdif with TF,VF,and SF,*** CTLP showed a strong negative correlation with TF and VF (r = -0.415 and -0.434,respectively,P < 0.001).The correlation between CTLP and SF was less significant (r = -0.313,P < 0.001).CONCLUSION: Fatty infiltration of the liver was correlated with amount of abdominal fat and VF was more strongly associated with fatty liver than SF.

关键词： Steatosis Computed tomography Abdominal fat Visceral fat Subcutaneous fat

Helmet-based noninvasive ventilation for acute exacerbation of chronic obstructive pulmonary disease: A case report

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World Journal of Clinical Cases 2020年第10期8卷 1939-1943页

作者： Mi Hwa Park Min Jeong Kim ah Jin Kim Man-Jong Lee Jung-Soo Kim Division of Pulmonology Department of Internal MedicineInha University HospitalIncheon 22332South Korea Division of Critical Care Medicine Department of Internal MedicineInha University HospitalIncheon 22332South Korea

BACKGROUND Noninvasive ventilation(NIV)reduces intubation rates,mortalities,and lengths of hospital and intensive care unit stays in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Helmet-based NIV is better tolerated than oronasal mask-based ventilation,and thus,allows NIV to be conducted for prolonged periods at higher pressures with minimal air *** SUMMARY A 73-year-old man with a previous diagnosis of COPD stage 4 was admitted to our medical intensive care unit with chief complaints of cough,sputum,and dyspnea of several days’*** 10 mo,he had been on oxygen at home by day and had used an oronasal mask-based NIV at *** intensive care unit admission,he breathed using respiratory accessory *** and signs of infection were detected,and infiltration was observed in the right lower lung field by chest ***,we diagnosed AECOPD by communityacquired *** admission,respiratory distress steadily deteriorated and invasive mechanical ventilation became ***,the patient refused this option,and thus,we selected helmet-based NIV as a salvage *** 3 d of helmet-based NIV,his consciousness level and hypercapnia recovered to his pre-hospitalization *** Helmet-based NIV could be considered as a salvage treatment when AECOPD patients refuse invasive mechanical ventilation and oronasal mask-based NIV is ineffective.

关键词： Acute exacerbation of chronic obstructive pulmonary disease Noninvasive ventilation Helmet Case report

Quantization of Time Independent Damping Systems Using WKB Approximation

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Journal of Applied Mathematics and Physics 2023年第9期11卷 2615-2620页

作者： Ola A. Jarab’ah Department of Applied Physics Tafila Technical University Tafila Jordan

In this work time independent damping systems are studied using Lagrangian and Hamiltonian for time independent damping, which are present through the factor eλq. The Hamilton Jacobi equation is formulated to find the Hamilton Jacobi function S using separation of variables technique. We can form this function in compact form of two parts the first part as a function of coordinate q, and the second part as a function of time t. Finally, we find the ability of these systems to quantize through an illustrative example.

关键词： Quantization Hamilton Jacobi Equation Hamilton Jacobi Function Momentum

Path Integral Quantization of Non-Natural Lagrangian

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Journal of Applied Mathematics and Physics 2023年第10期11卷 2932-2937页

作者： Ola A. Jarab’ah Department of Applied Physics Tafila Technical University Tafila Jordan

Path integral technique is discussed using Hamilton Jacobi method. The Hamilton Jacobi function of non-natural Lagrangian is obtained using separation of variables method. This function makes an important role in path integral quantization. The path integral is obtained as integration over the canonical phase space coordinates, which contains the generalized coordinate q and the generalized momentum p. One illustrative example is considered to explain the application of our formalism.

关键词： Path Integral Quantization Hamilton Jacobi Equation Non-Natural Lagrangian Hamilton Jacobi Function

Lagrangian Formulation of Fractional Nonholonomic Constrained Damping Systems

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Advances in Pure Mathematics 2023年第9期13卷 552-558页

作者： Ola A. Jarab’ah Department of Applied Physics Tafila Technical University Tafila Jordan

Fractional Euler Lagrange equations for fractional nonholonomic constrained damping systems have been presented. The equations of motion are obtained using fractional Euler Lagrange equations in a similar manner to the usual technique. The results of fractional method reduce to those obtained from classical method when μ →0 and α,β →1 are equal unity only. This work is discussed using illustrative example.

关键词： Euler-Lagrange Equations Nonholonomic Constraints Generalized Momenta

Prognostic value of alcohol consumptionand some other dietary habits for survival in a cohort of Chinese men with lung cancer

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Chinese Journal of Cancer 2017年第7期36卷 298-305页

作者： Wentao Li Lap ah Tse Joseph S.K.Au Kai Shing Yu Feng Wang Ignatius Tak-sun Yu JC School of Public Health and Primary Care The Chinese University of Hong Kong4F School of Public Health and Primary CarePrince of Wales Hospital Department of Clinical Oncology Hong Kong Adventist Hospital

Background:Alcohol consumption and some other dietary habits are thought to be associated with lung cancer ***,the effects of these habits on lung cancer prognosis have been studied *** purpose of this study was to address these gaps in ***:We studied a cohort of 1052 Chinese men in Hong Kong who were diagnosed with primary lung *** proportional hazards models were used to determine the prognostic values of consumption of alcohol,fresh fruits or vegetables,meat,and fried or preserved ***:Compared with never drinkers,men who drank alcohol 1-3 days per week had a more favorable lung cancer prognosis(hazard ratio[HR]:0.82,95%confidence interval[CI]0.68-0.97);however,this survival advantage was not significant in men who drank alcohol more frequently(HR:0.91,95%CI 0.73-1.14).Compared with men who consumed preserved or fried food only occasionally,men who consumed these foods frequently had a higher risk of lung cancer mortality(HR:1.20,95%CI 1.00-1.42).Conclusions:Occasional consumption of alcohol was a favorable survival factor for Chinese men with lung ***,this survival benefit did not exist for frequent drinkers of *** men with lung cancer who were frequent consumers of fried or preserved food had a worse prognosis than those who consumed these foods only occasionally.

关键词： Dietary habits Alcohol Lung cancer Prognosis Epidemiology

Polyherbal formula SC-E3 inhibits rheumatoid arthritis activity in a mouse model of type-Ⅱcollagen-induced arthritis

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Journal of Integrative Medicine 2021年第3期19卷 265-273页

作者： Ju-Yeon Park Young-Won Kwon Sun-ah Kim Sun-Dong Park Chang-Hyun Kim Jin-Hee Kim Ju-Hee Lee College of Korean Medicine Dongguk UniversityGoyang 10326Republic of Korea Department of Medicine College of MedicineDongguk UniversityGoyang 10326Republic of Korea Department of Biomedical Laboratory Science College of Health ScienceCheongju UniversityCheongju 28503Republic of Korea

Objective:SC-E3 is a polyherbal formula that contains five medicinal herbs used frequently in traditional herbal *** our previous study,we demonstrated the antioxidant and anti-inflammatory effects of *** present study examined the effects of SC-E3 in a mouse model of type-II collagen-induced arthritis(CIA).Methods:In vivo,male DBA/1 J mice were immunized by intradermal injection of bovine type-II collagen and complete or incomplete Freund’s adjuvant,to induce ***-E3 was orally administered daily for 23 *** vitro,bone marrow-derived macrophages(BMMs)were treated with macrophage colony-stimulating factor(M-CSF)and receptor activator of nuclear factor-j B ligand(RANKL)in the absence or presence of ***:Administrations of SC-E3 were found to have anti-arthritic effects in the joints of CIA mice,as evidenced by reduced paw swelling,bone erosion and deformation,inflammatory cell infiltration,and inflammation in synovial ***-E3 also reduced serum levels of tumor necrosis factor-a,interleukin-1 b,aspartate aminotransferase and alanine ***,tartrateresistant acid phosphatase-positive osteoclast numbers in the joints were significantly lower in SC-E3-treated CIA mice than in CIA *** addition,the differentiations of BMMs to multinucleated osteoclasts induced by M-CSF and RANKL stimulation were dose-dependently reduced by ***:These results suggest that SC-E3 possesses substantial anti-arthritic activity because it inhibits pro-inflammatory cytokines and osteoclastogenesis,and that SC-E3 has potential therapeutic use for the treatment of rheumatoid arthritis.

关键词： Herbal formula Anti-inflammatory Rheumatoid arthritis Collagen-induced arthritis Osteoclastogenesis