检索结果-南通市图书馆

疏风解毒胶囊治疗慢性阻塞性肺疾病急性加重期的疗效评价

在线全文

学校读者我要写书评

暂无评论

智慧健康 2022年第33期8卷 132-136页

作者：胡路华曹清张少兴新余钢铁集团公司中心医院呼吸内科江西新余338001

目的探讨疏风解毒胶囊治疗慢性阻塞性肺疾病急性加重期(acute exacerbation of chronic obstructive pulmonary disease,AECOPD)的临床疗效。方法收集住院时间为2016年12月-2018年12月的186例AECOPD患者,随机分为两组,分别为治疗组94例... 详细信息

目的探讨疏风解毒胶囊治疗慢性阻塞性肺疾病急性加重期(acute exacerbation of chronic obstructive pulmonary disease,AECOPD)的临床疗效。方法收集住院时间为2016年12月-2018年12月的186例AECOPD患者,随机分为两组,分别为治疗组94例和对照组92例,对照组采用抗感染和化痰等基础疗法,治疗组联用疏风解毒胶囊,治疗时间为7~10天。观察治疗前后,治疗组和对照组的肺功能指标(FEV_(1)、FVC、FEV_(1)/FVC)及血气分析(Pa02、PaCO_(2))的变化,并比较两组患者临床疗效。结果在治疗后,治疗组和对照组的FEV_(1)、FVC、FEV_(1)/FVC和PaO_(2)、PaCO_(2)均有所改善(P<0.05),且治疗组的改善疗效和临床总有效率更优(P<0.05)。在显效率、退热时间和咳嗽咳痰这些症状方面,治疗组更优(P<0.05)。结论疏风解毒胶囊治疗AECOPD疗效显著,能够退热及改善咳嗽、咳痰等症状,其具有显著的优势。

关键词：疏风解毒胶囊 AECOPD 疗效评价

在线全文

学校读者我要写书评

暂无评论

一种实现壳体柱面膨胀加载的实验技术研究

中国测试 2016年第10期42卷 29-33页

作者：张绍兴丁亮亮李翔宇张震宇卢芳云国防科学技术大学理学院湖南长沙410073

为分析金属壳体在柱面高压加载下的膨胀规律、结构强度和失效模式,设计一种实现壳体柱面膨胀加载的实验装置。该装置采用三轴试验机对高聚物填充物进行轴向压缩,填充物发生侧向膨胀从而实现对金属壳体内侧柱面的均匀加载,金属柱壳内侧... 详细信息

为分析金属壳体在柱面高压加载下的膨胀规律、结构强度和失效模式,设计一种实现壳体柱面膨胀加载的实验装置。该装置采用三轴试验机对高聚物填充物进行轴向压缩,填充物发生侧向膨胀从而实现对金属壳体内侧柱面的均匀加载,金属柱壳内侧压力和径向变形通过三轴试验机的轴压伺服系统、薄膜压力传感器和引伸计进行测量。利用该装置对含缺陷的LY-12硬铝柱壳进行加载得到在柱面加载下不同结构金属柱壳环向的拉伸应力和相对变形的关系,并发现金属柱壳在高强度柱面加载下发生剪切断裂失效,验证该加载测试方法的有效性,为研究材料和结构在柱面加载下的力学响应和失效模式提供依据。

关键词：金属圆柱壳柱面膨胀加载压力变形关系失效模式

Construction and properties of venlafaxine hydrochloride sustained release system based on hollow mesoporous silica microspheres

在线全文

学校读者我要写书评

暂无评论

Particuology 2024年第3期86卷 205-210页

作者： Chenjing Liang Lingling Shi Zhengguo Chen Lan Zhou Zhaoxia zhang Guoqing zhang School of Materials Science and Engineering Zhejiang Sci-tech UniversityHangzhouChina College of Textile Science and Engineering Zhejiang Sci-tech UniversityHangzhouChina Zhejiang Provincial Innovation Center of Advanced Textile Technology ShaoxingChina

The aim of this work is to develop a venlafaxine hydrochloride sustained release system based on hollow mesoporous silica microspheres(HMSMs).HMSMs were innovatively prepared with tetraethyl silicate(TEOS)as the precursor and volatile n-heptane as a soft *** obtained HMSMs show a well-defined hollow structure with an average size of 967 nm and pore volume of 0.85 cm^(3)/g,implying it is a potential drug ***,venlafaxine hydrochloride(VF)was absorbed in the HMSMs with a content of 37.67% or *** sustained release effect is further measured by the dissolution in-strument at 37℃ and 50 rpm in ultrapure *** results showed that the HMSMs/VF system shows good sustained release properties compared with sustained release tablets with hydroxypropyl meth-ylcellulose as the main *** HMSMs sustained release system appears to be a promising candidate for a sustained drug release.

关键词： Hollowmesoporous silica microspheres(HMSMs) Venlafaxine hydrochloride Drug loading Sustained release

鼓室硬化患者手术前后骨导听力变化的临床研究

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

临床耳鼻咽喉头颈外科杂志 2017年第16期31卷 1228-1230,1237页

作者：张珂马芙蓉宋为明潘滔柯嘉辛颖张绍兴陶立元北京大学第三医院耳鼻咽喉头颈外科北京100191 北京大学第三医院流行病学研究中心

目的:分析鼓室硬化患者手术前后骨导听力的变化,并探讨其可能的原因。方法:回顾性分析30例确诊为鼓室硬化患者的病例资料。结果:30例患者中,患侧术前骨导平均阈值为(21.06±8.88)dBHL,健耳术前骨导平均阈值为(16.78±8.97)dBHL,术前患... 详细信息

目的:分析鼓室硬化患者手术前后骨导听力的变化,并探讨其可能的原因。方法:回顾性分析30例确诊为鼓室硬化患者的病例资料。结果:30例患者中,患侧术前骨导平均阈值为(21.06±8.88)dBHL,健耳术前骨导平均阈值为(16.78±8.97)dBHL,术前患耳骨导听阈的提高具有统计学意义(t=3.072,P<0.01)。鼓室硬化患者骨导平均阈值、气导平均阈值和骨气导间距术后均较术前降低,差异均有统计学意义。术前骨导阈值在2 000Hz处最高,为(25.17±10.95)dB。术后骨导阈值在500、1 000、2 000 Hz 3个频率上的下降具有统计学意义(P<0.05或P<0.01)。鼓室硬化患者行乳突切开+鼓室成形术,术后骨导听阈较仅行鼓室成形术者有显著改善(P<0.05)。结论:鼓室硬化可导致患者骨导阈值升高;清除鼓室硬化灶的同时处理鼓窦及乳突的病灶以及重建传声结构,不仅可改善气导听力和缩小骨气导间距,而且还能使术后骨导听力显著改善。

关键词：鼓室硬化骨导测听法,纯音中耳炎

在线全文

学校读者我要写书评

暂无评论

外耳道胆脂瘤修订手术的临床病例分析

中华耳科学杂志 2021年第2期19卷 383-386页

作者：宋昱王宇鲁兆毅张绍兴黄宇童马芙蓉潘滔北京大学第三医院耳鼻咽喉科北京100191

目的分析外耳道胆脂瘤(EACC)修订手术病例的临床特点、处理及预后。方法回顾性分析2011-2019年EACC术后因外耳道狭窄、闭锁伴外耳道胆脂瘤复发10例(8名患者)于我院行修订手术的临床特征、修订手术要点。结果10例修订手术中,5例为外耳道... 详细信息

目的分析外耳道胆脂瘤(EACC)修订手术病例的临床特点、处理及预后。方法回顾性分析2011-2019年EACC术后因外耳道狭窄、闭锁伴外耳道胆脂瘤复发10例(8名患者)于我院行修订手术的临床特征、修订手术要点。结果10例修订手术中,5例为外耳道狭窄,5例为外耳道闭锁。3例术中发现外耳道骨质增生。修订手术与前次手术间隔0.5年~20年,平均5.3年±5.9年。行修订式手术前诊断:3例为单纯EACC,7例为EACC侵犯中耳。单纯EACC 3例均行胆脂瘤清理术,其中1例行耳甲腔成形术,2例行外耳道骨性扩大术。侵犯中耳7例中有3例行开放式乳突根治术,其他为单纯鼓室探查或完壁式鼓室成形术,但均在术中磨宽骨性外耳道。术中2例行自体皮移植术,1例植入脱细胞异体真皮,其他未植皮。术后再随访时间3个月~9年,平均2.8±2.9年。再随访病例中4例(2人)出现再次粘连闭锁,其中1例门诊处理后恢复可;其他6例(6人)随访期内无狭窄或闭锁。所有病例在最后一次手术后随访期内均未见胆脂瘤复发。我院2011-2019年诊断为EACC并手术病例总数为230例。上述10例病例中,5例由外院完成首次手术。故我院EACC手术再手术率为2.17%(5例/230例)。结论EACC术后有一定的再狭窄率,EACC广泛破坏外耳道皮肤,甚至环周皮肤缺损,是再狭窄的可能原因。年轻患者组织生长旺盛,较年老患者更易发生再狭窄。皮肤损失严重病例,进行适当的植皮十分必要,可能会减少再狭窄的发生。

关键词：外耳道胆脂瘤狭窄修订手术植皮

Symmetrization of quasi-regular patterns with periodic tilting of regular polygons

在线全文

学校读者我要写书评

暂无评论

Computational Visual Media 2024年第3期10卷 559-576页

作者： Zhengzheng Yin Yao Jin Zhijian Fang Yun zhang Huaxiong zhang Jiu Zhou Lili He School of Computer Science and Technology Zhejiang Sci-Tech UniversityHangzhou 310018China Zhejiang Provincial Innovation Center of Advanced Textile Technology Shaoxing 312000China School of Media Engineering Communication University of ZhejiangHangzhou 310018China

Computer-generated aesthetic patterns arewidely used as design materials in various fields. Themost common methods use fractals or dynamicalsystems as basic tools to create various patterns. Toenhance aesthetics and controllability, some researchershave introduced symmetric layouts along with thesetools. One popular strategy employs dynamical systemscompatible with symmetries that construct functionswith the desired symmetries. However, these aretypically confined to simple planar symmetries. Theother generates symmetrical patterns under theconstraints of tilings. Although it is slightly moreﬂexible, it is restricted to small ranges of tilingsand lacks textural variations. Thus, we proposed anew approach for generating aesthetic patterns bysymmetrizing quasi-regular patterns using general kuniformtilings. We adopted a unified strategy toconstruct invariant mappings for k-uniform tilings thatcan eliminate texture seams across the tiling ***, we constructed three types of symmetriesassociated with the patterns: dihedral, rotational, andreﬂection symmetries. The proposed method can beeasily implemented using GPU shaders and is highlyefficient and suitable for complicated tiling with regularpolygons. Experiments demonstrated the advantages of our method over state-of-the-art methods in terms ofﬂexibility in controlling the generation of patterns withvarious parameters as well as the diversity of texturesand styles.

关键词： quasi-regular patterns(QRP) k-uniform tilings invariant mappings symmetry aesthetic patterns

The superiority of nonconjugated structures in fluorescence:through-space ***-bond charge transfer

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2024年第9期67卷 3121-3130页

作者： Weihao Tu Zuping Xiong Lei Wang Jianyu zhang Jing Zhi Sun Haoke zhang Ben Zhong Tang MOE Key Laboratory of Macromolecular Synthesis and Functionalization Department of Polymer Science and EngineeringZhejiang UniversityHangzhou 310058China Zhejiang-Israel Joint Laboratory of Self-Assembling Functional Materials ZJU-Hangzhou Global Scientific and Technological Innovation CenterZhejiang UniversityHangzhou 311215China Centre of Healthcare Materials Shaoxing InstituteZhejiang UniversityShaoxing 312000China Department of Chemistry Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and ReconstructionThe Hong Kong University of Science and TechnologyHong Kong 999077China School of Science and Engineering Shenzhen Institute of Aggregate Science and TechnologyThe Chinese University of Hong KongShenzhen(CUHK-Shenzhen)Guangzhou 518172China

Constructing charge transfer(CT)state by introducing donor(D)and acceptor(A)is an efficient strategy to regulate the photophysical properties of luminescent *** CT-type luminophores are built onπ-conjugated fused-ring structures,which always show hybrid CT/locally excited(LE)states and luminescence quenching effect in the aggregate *** this work,eight conjugated biphenyl(BP)and nonconjugated diphenylmethane(DPM)derivatives with different donors and acceptors are synthesized to investigate the CT *** photophysical characterization and theoretical calculation demonstrate that the through-space CT(TSCT)in nonconjugated DA-DPM exhibit superior photophysical performance than the conjugated DA-BP with through-bond CT(TBCT),the main manifestations are as follows:(1)TSCT luminophores produce longer maximum emission wavelength(λ_(em))than the corresponding TBCT *** example,the longest λ_(em)of DMA-CN-DPM(DMA,dimethylamino)is 621 nm but the corresponding λ_(em)of DMA-CN-BP is only 480 nm.(2)TSCT-based DA-DPM demonstrates more sensitive responsiveness to environmental stimuli such as temperature and polarity.(3)Complete separation of the the highest occupied molecular orbital(HOMO)and the lowest unoccupied molecular orbital(LUMO)distribution exists in all kinds of conformation of DA-DPM,which was hard to realize in conjugated DA-BP.

关键词： through-space charge transfer through-space conjugation clusteroluminescence diphenylmethane

成人传染性单核细胞增多症误诊及鉴别诊断探讨

在线全文

学校读者我要写书评

暂无评论

临床耳鼻咽喉头颈外科杂志 2010年第24期24卷 1129-1131页

作者：张学东王丽张珂段静明段清川赵建辉张绍兴闫燕马芙蓉北京大学第三医院耳鼻咽喉科北京100191 北京市延庆县医院耳鼻咽喉科北京102100

目的:探讨成人传染性单核细胞增多症(IM)的临床特点。方法:回顾性分析50例成人IM住院患者的临床资料。结果:及时确诊组34例(68%),延迟诊断组16例(32%)。在IM典型的症状、体征、实验室检查方面,延迟诊断组与及时确诊组相比差异显著。结论... 详细信息

目的:探讨成人传染性单核细胞增多症(IM)的临床特点。方法:回顾性分析50例成人IM住院患者的临床资料。结果:及时确诊组34例(68%),延迟诊断组16例(32%)。在IM典型的症状、体征、实验室检查方面,延迟诊断组与及时确诊组相比差异显著。结论:IM临床表现复杂多样,对诊断缺乏特异性,详细的病史采集及全面的体格检查有助于早期诊断。

关键词：传染性单核细胞增多症误诊鉴别诊断

Mechanical Behaviors of Soft Elastomers Filled with LowMelting Alloys

在线全文

学校读者我要写书评

暂无评论

Acta Mechanica Solida Sinica 2023年第2期36卷 221-229页

作者： Zilu He Hong zhang Rui Xiao shaoxing Qu Key Laboratory of Soft Machines and Smart Devices of Zhejiang Province Department of Engineering MechanicsZhejiang UniversityHangzhou 310027China

Soft elastomers with mechanical properties similar to biological tissues have shown encouraging potential in applications of biomedical devices and stretchable *** the ability to enhance electric and thermal conductivity,embedding low melting alloys into soft elastomer matrix has received considerable attention in recent ***,the mechanical properties,especially the fatigue behaviors of these soft composites,have not been extensively ***,we fabricate two silicone elastomers filled with eutectic gallium-indium,a liquid metal alloy,which has a melting temperature around room *** cyclic loading–unloading tests are first performed on the composites with low melting alloys in either solid or fluid *** results show that the modulus and energy dissipation density of the composite increase with the ratio of the alloys when the deformation temperature is below the melting temperature,while these properties decrease with the ratio of alloys when they are in the fluid *** contrast,the failure strain shows an opposite *** tests are further performed on specimens with a precut to measure the fracture energy and fatigue *** is demonstrated that both fracture energy and fatigue threshold are significantly enhanced in the presence of low melting alloys regardless of their ***,we apply a continuum damage model to describe the Mullins effect of the soft composites observed in the loading–unloading cycles,which further reveals the change of mechanical properties with deformation for different compositions of soft composites.

关键词： Soft elastomer Low melting alloy Mullins effect Fatigue