检索结果-南通市图书馆

Journal of Magnesium and Alloys 2021年第6期9卷 2226-2228页

作者： Di Mei shaokang guan School of Materials Science and Engineering&Henan Key Laboratory of Advanced Magnesium Alloy Zhengzhou UniversityZhengzhou 450001HenanChina

Since physician Edward *** firstly tried to stop bleeding blood vessels with Mg wires in 1878[1],the history of Mg and its alloys as biomaterials has gone through more than 140 ***,in the latest 20 years,scientists from all over the world have carried out all-around research on Mg-based materials for the applications of vascular stents.

关键词： biomaterials bleeding alloys

A multi-functional MgF_(2)/polydopamine/hyaluronan-astaxanthin coating on the biodegradable ZE21B alloy with better corrosion resistance and biocompatibility for cardiovascular application

在线全文

学校读者我要写书评

暂无评论

Journal of Magnesium and Alloys 2024年第3期12卷 1102-1116页

作者： Yachen Hou Xueqi Zhang Jingan Li Liguo Wang shaokang guan School of Materials Science and Engineering and Henan Key Laboratory of Advanced Magnesium Alloy and Key Laboratory of Materials Processing and Mold Technology(Ministry of Education) Zhengzhou UniversityZhengzhou 450001China

The cardiovascular diseases(CVD)continue to be the major threat to global public health over the years,while one of the effective methods to treat CVD is stent *** magnesium(Mg)alloys have great potential applications in cardiovascular stents benefit from their excellent biodegradability and ***,excessive degradation rate and the delayed surface endothelialization still limit their further *** this study,we modified a Mg-Zn-Y-Nd alloy(ZE21B)by preparing MgF_(2) as the corrosion resistance layer,the dopamine polymer film(PDA)as the bonding layer,and hyaluronic acid(HA)loaded astaxanthin(ASTA)as an important layer to directing the cardiovascular cells *** electrochemical test results showed that the MgF_(2)/PDA/HA-ASTA coating improved the corrosion resistance of *** cytocompatibility experiments also demonstrated that this novel composite coating also selectively promoted endothelial cells proliferation,inhibited hyperproliferation of smooth muscle cells and adhesion of *** with the HAloaded rapamycin(RAPA)coating,our MgF_(2)/PDA/HA-ASTA coating showed better blood compatibility and cytocompatibility,indicating stronger multi-functions for the ZE21B alloy on cardiovascular application.

关键词： Biodegradable ZE21B alloy Reendothelialization Surface modification Hyaluronic acid Astaxanthin.

Exploring a balance between strength and ductility of hexagonal BN nanoplatelet reinforced ZK61 magnesium composite

在线全文

学校读者我要写书评

暂无评论

Journal of Magnesium and Alloys 2024年第5期12卷 1899-1910页

作者： Kewei Zhang Xiaolong Lu Yufeng Sun shaokang guan Yao Chen School of Materials Science and Engineering Zhengzhou UniversityZhengzhou 450001China Key Laboratory of Advanced Magnesium Alloys in Henan Province Zhengzhou UniversityZhengzhou 450002China Key Laboratory of Advanced Materials Processing&Mold Ministry of EducationZhengzhou 450002China School of Mechanical and Electrical Engineering Soochow UniversitySuzhou 215021China

The practical applications of magnesium(Mg)alloys are usually beset by their relatively low strength and limited *** we attempt to fabricate hexagonal BN nanoplatelet(BNNP)reinforced ZK61 magnesium composites using a combination of spark plasma sintering and friction stir *** resulting composites exhibit microstructural characteristics of homogeneous dispersion of BNNP in Mg matrix with refined equiaxed grains and(0002)basal texture roughly surrounding the pin column *** electron microscopy observation illustrates that trace amounts of Mg_(3)N_(2)and MgB_(2)form at BNNP-Mg interface,in which Mg_(3)N_(2)locates at the basal plane of a BNNP and MgB_(2)grows at its open *** spatial distribution of Mg_(3)N_(2)and MgB_(2)facilitates interfacial wetting and stronger BNNP-Mg interface in such a way that interfacial products act as anchors bonding between *** comparison with monolithic ZK61 alloy,the BNNP/ZK61 composites display simultaneous improvements in yield strength,hardness and ductility,achieving good strength-ductility *** research is expected to shed some light on BNNP potentials for designing and producing magnesium composites with high strength and good ductility.

关键词： BN nanoplatelet Magnesium composite Strength Ductility Spark plasma sintering Friction stir processing

Microstructure, mechanical properties and deformation mechanisms of an as-cast Mg–Zn–Y–Nd–Zr alloy for stent applications

在线全文

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2019年第7期35卷 1211-1217页

作者： Jianfeng Wang Hongbo Zhou Liguo Wang Shijie Zhu shaokang guan School of Materials Science and Engineering Zhengzhou University

A new Mg-2Zn-0.2Y -0.5N d-0.4Zr (wt%) alloy designed specially for stent applications has been developed. The as-cast alloy is featured with equiaxed grains with a mean size of about 40 μm and a small am ount of second phase (T phase) distributed discontinuously either at the grain boundaries or inside the grains. This alloy exhibits a tensile elongation of up to 35%, which is much larger than that of most reported other as-cast Mg alloys. The tensile deform ation mechanisms have also been investigated. The results show that, besides basal slip,{10-12} extension twining and non-basal pyramidal slips can also be observed at initial stage and later stage during tensile deform ation, respectively, which are responsible for the good room -tem perature ductility.

关键词： Magnesium alloys Vascular stents Microstructure Mechanical properties Deformation mechanisms

The therapeutic potential of MSC-EVs as a bioactive material for wound healing

在线全文

学校读者我要写书评

暂无评论

Engineered Regeneration 2021年第1期2卷 182-194页

作者： Yachen Hou Jingan Li shaokang guan Frank Witte School of Material Science and Engineering&Henan Key Laboratory of Advanced Magnesium Alloy&Key Laboratory of materials processing and mold technology(Ministry of Education) Zhengzhou University100 Science RoadZhengzhou 450001PR China Department of Prosthodontics Geriatric Dentistry and Craniomandibular DisordersCharite–Universitatsmedizin BerlinAssmannshauser Strasse 4–6Germany

In clinical trials,cell therapy,especially mesenchymal stem cells(MSC),contributed to wound treatment options in an innovative ***,there are some limitations of MSC during the application process,including strict maintenance requirements and unpredictable *** order to expand the scope of application and reduce the restrictions related to direct use of SMC,the mechanisms of stem cells need to be *** latest research found that the effect of cell therapy is achieved mainly through paracrine effects,and the major bioactive vesicles which responsible for the paracrine effects is *** is a kind of extracellular membrane vesicle,which secreted from various cells and contain proteins,lipids and nucleic acids,to coordinate intercellular *** this review,the main cells type and cytokines relevant to every healing stage has been discussed,and the research about MSC-derived exosomes that has therapeutic effects has been *** last,the potential application of exosomes as a bioactive material in the treatment of wound healing and related challenges as well as its possible solutions are discussed to reveal highly effective therapeutic strategies.

关键词： Exosomes Wound healing Mesenchymal stem cells Bioactive particles

Correlation between jerky flow and jerky dynamics in a nanoscratch on a metallic glass film

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Physics,Mechanics & Astronomy) 2020年第7期63卷 89-92页

作者： LiPing Yu DongXue Han JingLi Ren XiaoXiang Guo shaokang guan Gang Wang Henan Academy of Big Data Zhengzhou University.Zhengzhou 450052China College of Science Henan University of TechnologyZhengzhou 450001China Laboratory for Microstructures Institute of MaterialsShanghai UniversityShanghai 200444China School of Materials Science and Engineering Zhengzhou UniversityZhengzhou 450001China

Chaos has been well understood in dynamic system, however, how the chaotic behavior occur in jerky flow in material, is still not clear, and is lack of specific chaotic attractor. Here the jerky evolution of lateral force and the stair-like fluctuation of lateral displacement are observed for Ni62 Nb38(at.%) metallic glass film during nanoscratch process. This jerky flow is investigated by using the largest Lyapunov exponent, Kolmogorov entropy and fractal dimension, and chaotic behavior of lateral force-time and normal displacement-lateral displacement sequences is verified. In addition to time series analysis, it is found that jerk equation can be used to describe the jerky flow of the metallic-glass film during nanoscratch. More importantly, unambiguous chaotic attractor is presented by jerky dynamics using "jerk"-singularities, namely the total change rate of lateral force relative to scratch time. These reveal an inner connection between jerky flow and jerky dynamics in nanoscratch of a metallic-glass film.

关键词： metallic-glass film jerky flow jerky dynamics chaos

Mechanical and corrosion properties of biodegradable magnesium mini-tubes with different grain morphologies:Size and distribution

在线全文

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2024年第16期183卷 165-174页

作者： Xiang Wang Chun Chen Bozun Miao Zilong Wang Hua Huang shaokang guan guangyin Yuan National Engineering Research Center of Light Alloy Net Forming and Key State Laboratory of Metal Matrix Composites School of Materials Science and EngineeringShanghai Jiao Tong UniversityShanghai 200240 China School of Materials Science and Engineering Zhengzhou UniversityZhengzhou 450002China

Biodegradable magnesium(Mg)alloys have received much attention due to their biocompatibility and *** this study,to uncover the effects of grain morphologies,including grain size and distribution on mechanical and corrosion properties,biodegradable Mg-2.1Nd-0.2Zn-0.5Zr(wt.%)(denoted as JDBM)alloy mini-tubes for stent application with three typical microstructures were achieved success-fully by adjusting drawing *** with the bimodal structure exhibit the highest strengthductility balance attributed to the combined effects of fine grains and coarse grains,but show the fastest corrosion rate of about 1.00±0.136 mm/year mainly due to the formation of micro galvanic couples between coarse and fined *** with fine equiaxed grains show the lowest corrosion rate of about 0.17±0.059 mm/year,as well as uniform corrosion mode and mechanical properties of yield strength(YS)256±5.7 MPa,ultimate tensile strength(UTS)266±3.8 MPa,and elongation to failure(EL)13.5%±1.8%,attributed to the high-density grain *** with coarse equiaxed grains exhibit medium corrosion resistance and mechanical properties of about 175±4.8 MPa,221±4.0 MPa,and 21.53%±4.1%.Considering the mechanical and in vitro corrosion properties,biodegradable JDBM alloy implants are recommended to be composed of fine equiaxed grains,which can be used as microstructural targets for fabrication and processing.

关键词： Magnesium alloy Grain morphology Corrosion Mechanical properties Mini-tubes

Effect of Ca Micro-Alloying on the Microstructure and Anti-Corrosion Property of Mg0.5Zn0.2Ge Alloy

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Metallurgica Sinica(English Letters) 2024年第7期37卷 1147-1160页

作者： Bishan Cheng Depeng Li Baikang Xing Ruiqing Hou Pingli Jiang Shijie Zhu shaokang guan School of Materials Science and Engineering and Henan Key Laboratory of Advanced Magnesium Alloys Zhengzhou UniversityZhengzhou450001China Center of Advanced Analysis and Gene Sequencing Zhengzhou UniversityZhengzhou450001China Key Laboratory of Materials Processing and Mold Technology Ministry of EducationZhengzhou450002China

Magnesium and its alloys have attracting rising attention as one of biodegradable metallic ***,the rapid corrosion and severe localized corrosion still hinder their extensive applications in *** this study,micro-alloying of Ca(≤0.1 wt%)into Mg0.5Zn0.2Ge alloy developed in our previous work was explored to further enhance the corrosion resistance and alleviate the localized corrosion of the *** results reveal that the addition of Ca leads to the transformation of the cathodic Mg_(2)Ge phase in Mg0.5Zn0.2Ca alloy into anodic MgCaGe phase in Ca-containing alloys,thereby changing the galvanic couples in alloys during *** preferential dissolution of MgCaGe phase promotes the participation of Ca and Ge into the formation of corrosion products,resulting in the enrichment of Ca and Ge in the outmost of corrosion product layer,which stabilizes and passivates the corrosion product layer on Mg alloy ***,the enrichment of Zn at the corrosion interface seems to further hinder the corrosion of Mg *** of these factors confer a slower and more uniform corrosion on Mg0.5Zn0.2GexCa(x<0.1 wt%)alloy,which provides favorable candidates for the further processing to gain suitable biodegradable Mg alloys.

关键词： Magnesium alloy Micro-alloying Calcium Corrosion resistance

Shortening the manufacturing process of degradable magnesium alloy minitube for vascular stents by introducing cyclic extrusion compression

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Magnesium and Alloys 2024年第8期12卷 3204-3215页

作者： Kun Sheng Wenkai Li Peihua Du Di Mei Shijie Zhu Liguo Wang shaokang guan School of Materials Science and Engineering&Henan Key Laboratory of Advanced Magnesium Alloys Zhengzhou UniversityZhengzhou 450001China Key Laboratory of Advanced Materials Processing&Mold Ministry of Education Zhengzhou 450002China

Due to its excellent biocompatibility and biodegradability,Mg and its alloys are considered to be promising materials for manufacturing of vascular ***,the manufacture of high-precision and high-performance Mg alloys minitubes is still a worldwide problem with a long manufacturing processing caused by the poor workability of Mg *** solve this problem,the cyclic extrusion compression(CEC)was used to pretreat the billet by improving the workability of Mg alloys,finally shortening the manufacturing *** CEC treatment,the size of grains and second phase particles of Mg alloys were dramatically refined to 3.2μm and 0.3μm,*** after three passes of cold drawing,the wall thickness of minitube was reduced from 0.200 mm to 0.135 mm and a length was more than 1000 *** error of wall thickness was measured to be less than 0.01 mm,implying a high dimensional *** yield strength(YS),ultimate tensile strength(UTS)and elongation of finished minitube were 220±10 MPa,290±10 MPa and 22.0±0.5%,*** addition,annealing can improve mechanical property and corrosion resistance of minitubes by improving the homogeneity of the microstructure and enhancing the density of basal texture.

关键词： CEC ZE21B Mg alloy Minitube Shortened procedure Cold drawing Annealing

Preparation of Biodegradable Mg/β-TCP Biofunctional Gradient Materials by Friction Stir Processing and Pulse Reverse Current Electrodeposition

在线全文

学校读者我要写书评

暂无评论

Acta Metallurgica Sinica(English Letters) 2020年第1期33卷 103-114页

作者： Yabo Zhang Huiling Yang Shaoqian Lei Shijie Zhu Jianfeng Wang Yufeng Sun shaokang guan School of Materials Science and Engineering Zhengzhou UniversityZhengzhou 450001China Henan Key Laboratory of Advanced Magnesium Alloys Zhengzhou 450002China

Mg alloys,as a new generation of biodegradable bone implant materials,are facing two tremendous challenges of enhancing strength and reducing degradation rate in physiological environment to meet clinical *** this study,tricalcium phosphate(β-TCP)particles were dispersed in Mg–2 Zn–0.46 Y–0.5 Nd alloy by friction stir processing(FSP)to produce Mg-based functional gradient materials(Mg/β-TCP FGM).On the surface of Mg/β-TCP FGM,the hydroxyapatite(HA)coating was prepared by *** effects of FSP and electrochemical parameter on the microstructure,microhardness,bonding strength and corrosion performance of the Mg/β-TCP FGM were *** four passes of FSP,a uniform and fine-grained structure was formed in Mg/β-TCP and the microhardness increased from 47.9 to 76.3 *** to the samples withoutβ-TCP,the bonding strength of the Mg/β-TCP FGM increased from 23.1±0.462 to 26.3±0.526 MPa and the addition of degradableβ-TCP contributed to the in situ growth of HA *** thickness of HA coating could be dominated by controlling the parameters of *** to the results of immersion tests and electrochemical tests in simulated body fluid,it indicated that the degradation rate of the Mg/β-TCP FGM could be adjusted.

关键词： Biodegradable magnesium alloy Biofunctional gradient materials Friction stir processing Tricalcium phosphate(β-TCP) Electrodeposition