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Chinese Journal of Chemical Engineering 2023年第8期60卷 99-107页

作者： Ming Liu Ying Li Rui Wang Guoqiang shao Pengpeng lv Jun Li Qingshan Zhu State Key Laboratory of Multiphase Complex Systems Institute of Process EngineeringChinese Academy of SciencesBeijing 100190China School of Chemical&Environmental Engineering China University of Mining and Technology-BeijingBeijing 100083China School of Chemical Engineering University of Chinese Academy of SciencesBeijing 100049China

The performance of pearlescent pigment significantly affected by the grain size and the roughness of deposited film. The effect of TiCl_(4) concentration on the initial deposition of TiO_(2) on mica by atmospheric pressure chemical vapor deposition(APCVD) was investigated. The precursor concentration significantly affected the deposition and morphology of TiO_(2) grains assembling the film. The deposition time for fully covering the surface of mica decreased from 120 to 10 s as the TiCl_(4) concentration increased from 0.38%to 2.44%. The grain size increased with the TiCl_(4) concentration. The AFM and TEM analysis demonstrated that the aggregation of TiO_(2) clusters at the initial stage finally result to the agglomeration of fine TiO_(2) grains at high TiCl_(4) concentrations. Following the results, it was suggested that the nucleation density and size was easy to be adjusted when the TiCl_(4) concentration is below 0.90%.

关键词： Chemical vapor deposition TiO_(2)thin film Nucleation reaction Precursor concentration Pearlescent pigment

Immunological function of familial Mediterranean fever disease protein Pyrin

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Science China(Life Sciences) 2014年第12期57卷 1156-1161页

作者： YANG jie Ling XU Hao shao Feng National Institute of Biological Sciences National Laboratory of Biomacromolecules Institute of Biophysics Chinese Academy of Sciences

Pyrin,encoded by MEFV gene,is conserved in humans and *** in the MEFV gene are associated with the human autoinflammatory disease familial Mediterranean fever(FMF).Pyrin can interact with the inflammasome adaptor ASC and induce inflammatory caspase-1 activation in monocytic cells,but the physiological function of Pyrin has been unknown for many *** we summarize previous studies of Pyrin function under the context of FMF and immunity,and discuss a recent study demonstrating that Pyrin forms an inflammasome complex for caspase-1 activation in innate *** inflammasome detects inactivating modifications of host Rho GTPases by diverse bacterial toxins and infections,including Clostridium difficile glucosylating cytotoxin Tcd B,FIC-domain adenylyltransferase effectors from Vibrio parahaemolyticus and Histophilus somni,ADP-ribosylating Clostridium botulinum C3 toxin as well as Burkholderia cenocepacia *** mode of Pyrin action,i.e.,sensing pathogen virulence activity rather than directly recognizing a microbial molecule,represents a new paradigm in innate immunity.

关键词： Pyrin MEFV Rho GTPase inflammasome Guard Model

Cell-cell contact-induced gene editing/activation in mammalian cells using a synNotch-CRISPR/Cas9 system

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Protein & Cell 2020年第4期11卷 299-303页

作者： Hongxin Huang Xin Zhang jie lv Hongcheng Yang Xinlong Wang Shufeng Ma Ruoyang shao Xin Peng Ying Lin Zhili Rong School of Basic Medical Sciences Cancer Research InstituteSouthern Medical UniversityGuangzhou 510515China Dermatology Hospital Southern Medical UniversityGuangzhou 510091China Guangzhou Regenerative Medicine and Health Guangdong Laboratory Guangzhou 510005China

Dear Editor,The CRISPR system has been widely used for genome manipulation in various cells,tissues and whole *** an increasing variety of inducible CRISPR systems have been exploited for a variety of applications,such as chemical switch(Zetsche et al.,2015),photo switch(shao et al.,2018)and solution ligand switch(Baeumler et al.,2017;Kipniss et al.,2017;Schwarz et al.,2017)systems,a cell-cell interaction inducible system is *** synthetic Notch(synNotch)receptor is a recently developed cell-cell contact sensing platform,which contains a customized extracellular sensor module,a transmembrane core domain of native Notch,and a customized intracellular responder module(Morsut et al.,2016).

关键词： CRISPR/Cas9 system custom

Influence of the Earth's rotation on measurement of gravitational constant G with the time-of-swing method

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Chinese Physics B 2020年第2期29卷 137-141页

作者： jie Luo Tao Dong Cheng-Gang shao Yu-jie Tan Hui-jie Zhang School of Mechanical Engineering and Electronic Information China University of GeosciencesWuhan 430074China MOE Key Laboratory of Fundamental Physical Quantities Measurement&Hubei Key Laboratory of Gravitation and Quantum Physics PGMF and School of PhysicsHuazhong University of Science and TechnologyWuhan 430074China

In the measurement of the Newtonian gravitational constant G with the time-of-swing method,the influence of the Earth's rotation has been roughly estimated before,which is far beyond the current experimental ***,we present a more complete theoretical modeling and assessment *** figure out this effect,we use the relativistic Lagrangian expression to derive the motion equations of the torsion *** the correlation method and typical parameters,we estimate that the influence of the Earth's rotation on G measurement is far less than 1 ppm,which may need to be considered in the future high-accuracy experiments of determining the gravitational constant G.

关键词： the Earth's rotation relativistic Lagrangian G measurement time-of-swing method

Center for Elliptic Quantum Group Eτ，η(sln)

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Communications in Theoretical Physics 2003年第1期39卷 67-72页

作者： Zhao shao-You Shi Kang-jie Yue Rui-Hong Institute of Modern Physics Northwest University Xi'an 710069 China

We give the center of the elliptic quantum group in general cases. Based on the dynamical Yang-Baxter relation and the fusion method, we prove that the center commutes with all generators of the elliptic quantum group. Then for a kind of assumed form of these generators, we find that the coefficients of these generators form a new type of closed algebra. We also give the center for the algebra.

关键词：凝聚物理椭圆量子群 YangBaxter关系式

Boundedness of Hausdorff operators on the power weighted Hardy spaces

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Applied Mathematics(A Journal of Chinese Universities) 2017年第4期32卷 462-476页

作者： CHEN jie-cheng HE shao-yong ZHU Xiang-rong Department of Mathematics Zhejiang Normal University Jinhua 321004 China

In this paper, we consider the two-dimensional Hausdorff operators on the power weighted Hardy space H;（R;）（ -1 ≤α≤0）, defined by H;f（x）=∫R;Φ（u）f(A（u）x)du,where Φ∈L;oc;（R;）,A（u） = (α;（u）);is a 2×2 matrix, and each α;is a *** obtain that HΦ,A is bounded from H;（R;）（ -1≤α≤0） to itself, if∫R2|Φ（u）‖det A;（u）|‖A（u）‖;ln(1+‖A;（u）‖;/|det A;（u）|)du<∞.This result improves some known theorems, and in some sense it is sharp.

关键词： Hausdorff operator Hardy space power weight

Research of air-cushion isolation effects on high arch dam reservoir

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Acta Mechanica Sinica 2011年第5期27卷 675-686页

作者： shao-jie Zhang Jiang Chen Yuan-Ze Zhang Hao-Wu Liu College of Hydraulic ＆ Hydroelectric Engineering Sichuan University610065 Chengdu China Scientific Research Institute of Kunming Investigationand Design Institute China Hydropower Engineering Consultation Group Company650033 Kunming China Institute of Mountain Harzards and Environment Chinese Academy of Sciences610041 Chengdu China

A three-dimensional （3D） finite element model of air-cushion isolated arch dam is presented with the nonlinear gas-liquid-solid multi-field dynamic coupling effect taken into *** this model,the displacement formulation in Lagrange method,pressure formulation in Euler method,nonlinear contact model based on Coulomb friction law are applied to the air-cushion,reservoir and contraction joint domain,*** dynamic response of Jinping I arch dam with a height of 305 m is analyzed using the seismic records of the Wenchuan Earthquake in *** results show that the air-cushion isolation reduces significantly the hydrodynamic pressure as well as the opening width for the contraction joints of high arch dam.

关键词： Air-cushion · Gas-liquid-solid multi-field coupling · Contraction (transverse) joint · Hydrodynamic pressure · Wenchuan Earthquake

DNA Hydrogels Formed of Bended DNA Scaffolds and Properties Study

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Chinese Journal of Polymer Science 2017年第10期35卷 1307-1314页

作者： hao-yang jia jie-zhong shi yu shao 刘冬生 Key Laboratory of Organic Optoelectronics & Molecular Engineering of the Ministry of Education Department of Chemistry Tsinghua University Beijing 100084 China

In recent years, DNA supramolecular hydrogels have attracted much attention due to their injectability, biocompatibility, responsiveness and self-healing properties. In this work, we designed a linear DNA brick containing one duplex with two cytosine（C）-rich sequence on both ends. This brick can first assemble to form duplex under p H 8 condition. After adjusting the p H to 5, the C-rich sequence tends to form intermolecular i-motif structure, which joins the linear DNA molecules together to form interlocked cyclic structures and yield the DNA hydrogel. By adjusting the length and bending curvature of the duplex part of the molecule, one can change the basic unit of the hydrogel structure to tune the properties of the DNA hydrogel.

关键词： Linear DNA Hydrogel Bended structures

Subhalo Abundance and Satellite Spatial Distribution in Milky Way-Andromeda-like Paired Haloes

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Research in Astronomy and Astrophysics 2022年第12期22卷 344-352页

作者： Kemeng Li Shi shao Ping He Qing Gu jie Wang College of Physics Jilin UniversityChangchun 130012China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China Center for High Energy Physics Peking UniversityBeijing 100871China School of Astronomy and Space Science University of Chinese Academy of SciencesBeijing 100049China

We study the subhalo and satellite populations in haloes similar to the Milky Way(MW)-Andromeda paired configuration in the Millennium II and P-Millennium *** find subhaloes are 5%–15%more abundant in paired haloes than their isolated counterparts that have the same halo mass and large-scale environmental *** haloes tend to reside in a more isotropic environment than isolated haloes,the shear tensor of their large-scale tidal field is possibly responsible for this *** also study the thickness of the spatial distribution of the top 11 most massive satellite galaxies obtained in the semi-analytic galaxy sample constructed from the Millennium II ***,satellites that have lost their host subhaloes due to the resolution limit of the simulation have been taken into *** a result,we find that the difference in the distribution of the satellite thickness between isolated and paired haloes is indistinguishable,which suggests that the paired configuration is not responsible for the observed plane of satellites in the *** results in this study indicate the paired configuration could bring some nonnegligible effect on the subhalo abundance in the investigation of the MW's satellite problems.

关键词： galaxies:abundances galaxies:halos galaxies:structure (galaxies:)Local Group (cosmology:)dark matter methods:numerical

Microinjection of a growth factor cocktail affects activated microglia in the neocortex of adult rats

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Neural Regeneration Research 2020年第9期15卷 1709-1715页

作者： Ruo-Xu Liu jie Ma Ning Guo shao-Jun Liu State Key Laboratory of Proteomics and Department of Neurobiology Institute of Military Cognition and Brain Sciences

Microglia, as the resident immune cells in the central nervous system, play important roles in regulating neuronal processes, such as neural excitability, synaptic activity, and apoptotic cell clearance. Growth factors can activate multiple signaling pathways in central nervous system microglia and can regulate their immune effects, but whether growth factors can affect the morphological characteristics and ultrastructure of microglia has not been reported. After microinjecting 300 nL of a growth factor cocktail, including 10 μg/mL epidermal growth factor, 10 μg/mL basic fibroblast growth factor, 10 μg/mL hepatocyte growth factor and 10 μg/mL insulin-like growth factor into adult rat cortex, we found that the number of IBA1-positive microglia around the injection area increased significantly, indicating local activation of microglia. All CD68-positive labeling co-localized with IBA1 in microglia. Cell bodies and protrusions of CD68-positive cells were strongly attached to or were engulfing neurons. Characteristic huge phagosomes were observed in activated phagocytes by electron microscopy. The phagosomes generally included non-degraded neuronal protrusions and mitochondria, yet they contained no myelin membrane or remnants, which might indicate selective phagocytosis by the phagocytes. The remnant myelin sheath after phagocytosis still had regenerative ability and formed "myelin-like" structures around phagocytes. These results show that microinjection of a growth factor cocktail into the cerebral cortex of rodents can locally activate microglia and induce selective phagocytosis of neural structures by phagocytes. The study was approved by the Institute of Laboratory Animal Science, Beijing Institute of Basic Medical Sciences(approval No. IACUC-AMMS-2014-501) on June 30, 2014.

关键词： adult neocortex CD68 IBA1 microinjection phagocyte selective phagocytosis ultrastructure