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Journal of Ocean University of China 2015年第3期14卷 522-532页

作者： shao Chen LU Xiaoteng ma Honggang The Key Laboratory of Biomedical Information Engineering of Ministry of Education School of Life Science and Technology Xi'an Jiaotong University Laboratory of Protozoology Institute of Evolution and Marine Biodiversity Ocean University of China

Oxytrichidae s. l. ciliates usually have 18 frontal-ventral-transverse cirri which are clustered to six distinct groups usu- ally originating from six longitudinal primordia segregating 1, 3, 3, 3, 4, 4 cirri. During morphogenesis, three dorsal kinetics anlagen are primarily formed. Fragmentation of kinety 3 usually present, while sometimes secondarily lost. Dorsomarginal kineties are formed, while sometimes lost. Oxytrichids tend to have overlapping characters, e.g. cell shape and size, infraciliature, pellicle fea- tures. This makes a great problem for genera separation. In the present work, all typical 18 frontal-ventral-transverse-cirri Oxytrichi- dae s. 1. genera were revised systematically based on their living morphology, ciliature patterns and dorsal morphogenetic features. The outline of the genera, the schematic illustrations, and the key to typical 18 frontal-ventral-transverse-cirri genera of Oxytrichidae s. l. were clarified. Additionally, some morphological and morphogenetic patterns were summarized and compared.

关键词： Oxytrichinae Sporadotrichida Stylonychinae taxon

Exploring the molecular mechanisms and potential therapeutic strategies of ferroptosis in ovarian cancer

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BIOCELL 2024年第3期48卷 379-386页

作者： LISHA ma WANQI shao WEILI ZHU Department of Gynecology Jiaxing University Master Degree Cultivation BaseZhejiang Chinese Medical UniversityJiaxingChina Department of Gynecology Jiaxing University Affiliated Women and Children’s HospitalJiaxingChina

The morbidity rate of ovarian cancer,a malignant tumour in gynaecological tumours,is rising,and it is considered to be the most lethal *** majority of patients are typically diagnosed during the advanced stages of the illness due to the elusive characteristics of ovarian cancer and an absence of highly sensitive and speciﬁc diagnostic *** excision of the lesions,along with chemotherapy,is the conventional treatment for ovarian cancer;however,resistance to platinum-based chemotherapeutic drugs and molecular targeted therapies frequently *** the survival rate and prognosis of patients with end-stage or recurring ovarian cancer requires the identiﬁcation of new therapeutic targets due to the absence of efﬁcient medications,and this has emerged as a highly demanding *** have demonstrated that ferroptosis effectively hinders the proliferation of ovarian cancer and induces the demise of malignant *** is composed of the cystine/glutamate antiporter system(the system Xc-)and glutathione peroxidase 4(GPX4).Solute carrier family 7 member 11(SLC7A11)and solute carrier family 3 member 2(SLC3A2)play crucial roles in the regulation of ferroptosis by facilitating the uptake of cystine into cells and the efﬂux of glutamate out of cells,*** cells,GPX4 is the exclusive enzyme employed for reducing liposomal peroxide through glutathione peroxidase *** occurrence of ferroptosis in ovarian cancer is strongly associated with three main pathways,namely,the GPX4-glutathione(GSH)protective pathway,the ferroptosis suppressor protein 1(FSP1)-coenzyme Q10(CoQ10)protective pathway,and the guanosine 5'-triphosphate cyclohydrolase I(GCH1)protective *** ovarian cancer cells,the postsynaptic density-95,discs-large,zona occludens 1(PDZ)-binding motif-angiopoietin-like 4-nicotinamide adenine dinucleotide phosphate oxidases 2(TAZ-ANGPTL4-NOX2)pathway can be regulated by Yes-associated protein(YAP)/TAZ,a downstream

关键词： Ovarian cancer Ferroptosis Therapy

Uncertainty relations based on skew information with quantum memory

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Science China(Physics,Mechanics & Astronomy) 2017年第1期60卷 62-64页

作者： ZhiHao ma ZhiHua Chen shao-Ming Fei School of mathematical Sciences Shanghai Jiaotong University Shanghai 200240 China Department of Applied mathematics Zhejiang University of Technology Hangzhou 310014 China School of mathematical Sciences Capital Normal University Beijing 100048 China max-Planck-Institute for mathematics in the Sciences Leipzig 04103 Germany

Uncertainty principle is one of the most fascinating features of the quantum world. It asserts a fundamental limit on the precision with which certain pairs of physical properties of a particle, such as position and momentum, can not be si- multaneously known. The uncertainty principle has attracted considerable attention since the innovation of quantum me- chanics and has been investigated in terms of various types of uncertainty inequalities： in terms of the noise and dis- turbance, according to successive measurements, as informa- tional recourses in entropic terms, by means of majorization technique and based on sum of variances and standard devia- tions.

关键词： Uncertainty relations based on skew information with quantum memory

Parameters inversion of high central core rockfill dams based on a novel genetic algorithm

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Science China(Technological Sciences) 2016年第5期59卷 783-794页

作者： ZHOU Wei LI shao Lin ma Gang CHANG Xiao Lin ma Xing ZHANG Chao State Key Laboratory of Water Resources and Hydropower Engineering Science Wuhan University Changjiang Institute of Survey Planning Design and Research

Parameters identification of rockfill materials is a crucial issue for high rockfill dams. Because of the scale effect, random sampling and sample disturbance, it is difficult to obtain the actual mechanical properties of rockfill from laboratory tests. Parameters inversion based on in situ monitoring data has been proven to be an efficient method for identifying the exact parameters of the rockfill. In this paper, we propose a modified genetic algorithm to solve the high-dimension multimodal and nonlinear optimal parameters inversion problem. A novel crossover operator based on the sum of differences in gene fragments(So DX) is proposed, inspired by the cloning of superior genes in genetic engineering. The crossover points are selected according to the difference in the gene fragments, defining the adaptive length. The crossover operator increases the speed and accuracy of algorithm convergence by reducing the inbreeding and enhancing the global search capability of the genetic algorithm. This algorithm is compared with two existing crossover operators. The modified genetic algorithm is then used in combination with radial basis function neural networks(RBFNN) to perform the parameters back analysis of a high central earth core rockfill dam. The settlements simulated using the identified parameters show good agreement with the monitoring data, illustrating that the back analysis is reasonable and accurate. The proposed genetic algorithm has considerable superiority for nonlinear multimodal parameter identification problems.

关键词： rockfill dam parameters back analysis genetic algorithm crossover operator sum of differences in gene fragments

A bidirectional-transformation-based framework for software visualization and visual editing

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Science China(Information Sciences) 2014年第5期57卷 147-169页

作者： HE Xiao HU ChangJun ma ZhiYi shao WeiZhong School of Computer and Communication Engineering University of Science and Technology Beijing Key Laboratory of High Confidence Software Technologies of Ministry of Education (Peking University)

Software visualization and visual editing are important and practical techniques to improve the development of complex software systems.A challenge when applying the two technologies is how to realize the correspondence,a bidirectional relationship,between the data and its visual representation *** many tools and frameworks have been developed to support the construction of visual tools,it is still complicated and error-prone to realize the bidirectional *** this paper,we propose a model-driven and bidirectional-transformation-based framework for data visualization and visual *** approach mainly focuses on 1)how to define and manage graphical symbols in the model form and 2)how to specify and implement the bidirectional relationship based on the technique of bidirectional model ***,a prototype tool and four case studies are presented to evaluate the feasibility of our work.

关键词： model-driven development bidirectional transformation software visualization visual language visual editing

Simulation of Air Source Heat Pump with Refrigerant Injection for Heating Operation

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Transactions of Nanjing University of Aeronautics and Astronautics 2018年第5期35卷 739-748页

作者： Liu Haibo shao Shuangquan ma Guoyuan Fan Boyuan College of Environmental and Energy Engineering Beijing University of Technology CAS Key Laboratory of Cryogenics Technical Institute of Physics and Chemistry

An air source heat pump(ASHP)with refrigerant injection is proposed for the air conditioning system of electric vehicles(EVs),especially for efficient heating in cold winter,when there is no wasted heat of *** simulation model is built with the framework of two-phase fluid network,where the compressor is separated as two compressors and the economizer is treated as two heat exchangers in the injection path and the main refrigerant *** the validated simulation model,the heating performance is analyzed,and the results show that the coefficient of performance(COP)of ASHP with refrigerant injection is higher than 1.4 and the discharge temperature is less than 100℃ when the outdoor temperature is-20℃.The above performance ensures that the air conditioning system and EVs can operate normally with high efficiency even in the cold winter,which is much helpful for the practicability of EVs.

关键词： heat pump refrigerant injection air conditioning simulation electric vehicle(EV)

Stellar reaction rate of 55Ni（p,γ）56Cu in Type I X-ray bursts

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Nuclear Science and Techniques 2019年第9期30卷 94-102页

作者： shao-Bo ma Li-Yong Zhang Jun Hu Institute of Modern Physics Chinese Academy of Sciences Lanzhou 730000 China University of Chinese Academy of Sciences Beijing 100049 China College of Nuclear Science and Technology Beijing Normal University Beijing 100875 China

56Cu is close to the waiting-point nucleus 56Ni and lies on the rapid proton capture（rp） process path in Type I X-ray bursts（XRBs）. In this work, we obtained a revised thermonuclear reaction rate of 55Ni（p,γ）56Cu in the temperature region relevant to XRBs. This rate was recalculated based on the recent experimental level structure in 56Cu, the recently measured proton separation energy of Sp = 579.8（7.1） keV, together with shell-model calculation, and the mirror nuclear structure in 56Co. The associated uncertainties in the rates were estimated by a Monte Carlo method. Our revised rate is significantly different from the recent results, which were partially based on experimental results; in addition, we found that a result in a previous work was incorrect. We recommend our revised rate to be incorporated in the future astrophysical network calculations.

关键词： Nuclear astrophysics Reaction rate X-ray burst

Transport of cadmium from soil to grain in cereal crops: A review

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Pedosphere 2021年第1期31卷 3-10页

作者： Jian Feng ma Ren Fang SHEN Ji Feng shao Institute o f Plant Science and Resources Okayama UniversityChuo 2-20-1Kurashiki 710-0046Japan State Key Laboratory of Soil and Sustainable Agriculture Institute of Soil ScienceChinese Academy of SciencesNanjing 210008China State Key Laboratory of Subtropical Silviculture Zhejiang A&F UniversityLin'An 311300China

Due to rapid urbanization and industrialization, many soils for crop production are contaminated by cadmium(Cd), a heavy metal highly toxic to many organisms. Cereal crops such as rice, wheat, maize, and barley are the primary dietary source of Cd for humans, and reducing Cd transfer from soil to their grains is therefore an important issue for food safety. During the last decade, great progress has been made in elucidating the molecular mechanisms of Cd transport, particularly in rice. Inter-and intraspecific variations in Cd accumulation have been observed in cereal crops. Transporters for Cd have been identified in rice and other cereal crops using genotypic differences in Cd accumulation and mutant approaches. These transporters belong to different transporter families and are involved in the uptake, vacuolar sequestration, root-to-shoot translocation, and distribution of Cd. Attempts have been made to reduce Cd accumulation in grains by manipulating these transporters through overexpression or knockout of the transporter genes, as well as through marker-assisted selection breeding based on genotypic differences in Cd accumulation in the grains. In this review, we describe recent progress on molecular mechanisms of Cd accumulation in cereal crops and compare different molecular strategies for minimizing Cd accumulation in grains.

关键词： barley gene knockout gene overexpression genotypic difference maize rice transporter wheat

Synthesis of TiO_2 photocatalysts with abundant surface defects using a TiO_2@NaCl precursor

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Science China Chemistry 2012年第6期55卷 1155-1159页

作者： shao Yue ma Yong College of Chemistry Chemical Engineering and Food Sqfbty Bohai University Jinzhou 121013 China

TiO2 nanoparticles have been synthesized by using a TiO2@NaCl core-shell structure as the precursor. The surface defects were well preserved by the NaCl shell, and therefore high oxygen adsorption capacity was observed. After the NaC1 shell was removed, the resulting pure TiO2 nanoparticles were of anatase phase and uniform size of around 20-24 nm. The presence of an abundance of surface defects contributes to the high photocatalytic activity of the synthesized materials, and the TiO： mate- rials obtained from the TiO2@NaCl precursor can be used as efficient photocatalysts for degradation of rhodamine B under UV light irradiation.

关键词： defects nanocrystalline materials X-ray photoelectron spectroscopy (XPS) core-shell photocatalysis

Perlecan and synaptophysin changes in denervated skeletal muscle

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Neural Regeneration Research 2012年第17期7卷 1293-1298页

作者： Kai ma Zhifeng Huang Jianfeng ma Longquan shao Huiming Wang Yanliang Wang Department of Oral and maxillofacial Surgery Affiliated Hospital of Stomatology Medical College of Zhejiang University Hangzhou 310006 Zhejiang Province China Department of Oral and maxillofacial Surgery Affiliated Hospital of Stomatology Wenzhou Medical College Wenzhou 325027 Zhejiang Province China School of Pharmacy Wenzhou Medical College Wenzhou 325000 Zhejiang Province China Department of Stomatology Nanfang Hospital Southern Medical University Guangzhou 510515 Guangdong Province China

The present study observed sciatic nerve and gastrocnemius muscle changes in denervated rats using morphology methods, and assessed expression of perlecan, an extracellular matrix component, which is located at the skeletal muscle cell surface as acetylcholine esterase, as well as synaptophysin, a synaptic marker. Results showed degeneration and inflammation following transection of the sciatic nerve. In addition, the sciatic nerve-dominated skeletal muscle degenerated with mild inflammation, indicating that skeletal muscle atrophy primarily contributed to denervation-induced nutritional disturbances. With prolonged injury time （1-4 weeks post-injury）, perlecan expression gradually decreased and reached the lowest level at 4 weeks, but synaptophysin expression remained unchanged after denervation. Results suggested that perlecan expression was more sensitive to denervation and reflected regional extracellular matrix changes following denervation.

关键词： perlecan synaptophysin extracellular matdx acetylcholine esterase neuromuscular junction denervated skeletal muscle sciatic nerve neural regeneration