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[1-(4-Nitrobenzyl)-2-butyl-4-chloro-1<i>H</i>-imidazol-5-yl]-4, 5-dihydro-1-phenyl-1<i>H</i>-pyrazole: Synthesis, Anti-Inflammatory and Analgesic Activities

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Open Journal of Medicinal Chemistry 2013年第2期3卷 50-54页

作者： S. Sreenivasa B. J. shankar Department of Studies and Research in Chemistry Tumkur University Tumkur India

In the present investigation, series of Bis (heterocycle)s bearing pyrazoline in combination of the imidazole derivatives have been synthesized via 1,3-dipolar cycloaddition reactions of N-(nitrobenzyl)-imidazole nitrile imines with different dipolarophiles. All the newly synthesized compounds were characterized and screened for analgesic-anti-inflammatory activities and were compared with the standard drugs. The compounds exhibited excellent anti-inflammatory and analgesic activities. Out of the compounds studied 4b, 4d and 4g compounds shown statistically significant activity comparable to the standard drugs Ibuprofen and Aspirin at the same dose.

关键词： Anti-Inflammatory Analgesic N-(nitrobenzyl)-imidazole aldehyde Chloramine-T

Synthesis of graphene Oxide from Hydrogenated Diamond Like Carbon and Protein Immobilization onto It: Characterization and Study of Practical Utility

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Journal of Materials Science and Chemical Engineering 2021年第1期9卷 32-41页

作者： Subhashis Bala Reshmi Bose Shaona Chaterjee Sanjit Sarkar Indranil Saha Hari shankar Biswas Department of Chemistry Surendranath College Kolkata India Chakdaha Nadia India Department of Basic Science and Humanities University of Engineering and Management Newtown India Department of Chemistry Presidency University Kolkata India Department of Physics Surendranath Evening College Kolkata India Sripat Singh College Jiagangj Murshidabad West Bengal India

In the last few years, graphene oxide material and biomolecules studies have increased. The various synthesis methods of graphene oxide are constantly pursued to improve and provide safer and more effective alternatives. Though the preparation of graphene oxide from graphite powder or graphite flake through Hummers method is one of the oldest techniques but still now it is one of the most suitable methods. Here, graphene Oxide has been prepared from a tunable material Hydrogenated diamond like carbon (HDLC) which is an atomically smooth surface that can be deposited on high-surface area Silicon (100) wafer plate. The HDLC film was heated at a fixed temperature of 900°C for 30 min in high vacuum ~1 × 10−6 torr and oxygenated at room temperature. A synthetic sequence is described involving Oxidation of annealed HDLC (A-HDLC). Raman measurements confirm the g and D peak by Oxidation of A-HDLC and FTIR confirms functional groups. Atomic force microscopy (AFM) images describe the surface of A-HDLC, Oxidized graphene and BSA immobilized gO. This gO onto Silicon substrate offers many technical advantages than as oxidized graphene Synthesis from other Chemical methods.

关键词： Carbon Diamond graphene Oxide AFM Raman FTIR

碳纳米管纱作为填料应用于硝基芳烃污水处理（英文）

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新型炭材料 2016年第4期31卷 415-423页

作者： Sushil R.Kanel Heath Misak Dhriti Nepat shankar Mall Seth W.Brittle Ioana Sizemore David M.Kempisty Mark N.goltz Department of Systems Engineering and Management Air Force Institute of Technology2950 Hobson WayWright-Patterson AFBOH 45433-7765USA Department of Aeronautics and Astronautics Air Force Institute of Technology2950 Hobson WayWright-Patterson AFBOH 45433-7765USA Materials and Manufacturing Directorate Air Force Research LaboratoryWright-Patterson AFBOhio 45433-7702USA Department of Chemistry Wright State University3640 Colonel Glen HighwayDaytonOH 45435USA

碳纳米管纱(CNTY)因具有优异的力学强度、化学稳定性、热稳定性和高比表面积而成为去除废水中有机污染物的潜在材料。本文将CNTY用于含2,4-二硝基甲苯(DNT)的污水处理。CNTY对DNT的吸附能力与文献报道值作对比研究,同时探讨吸附动力学... 详细信息

碳纳米管纱(CNTY)因具有优异的力学强度、化学稳定性、热稳定性和高比表面积而成为去除废水中有机污染物的潜在材料。本文将CNTY用于含2,4-二硝基甲苯(DNT)的污水处理。CNTY对DNT的吸附能力与文献报道值作对比研究,同时探讨吸附动力学。采用SEM-EDX、HRTEM、Raman与XPS表征CNTY吸附DNT前后的尺寸、表面形貌及表面化学。结果表明,经CNTY对DNT污水处理后的水质达到实验室无离子水级纯度。CNTY对DNT吸附符合Freundlich吸附等温线,Freundlich参数由K/nF为55.0 mg/g(L/mg)1,指数1/n为0.737得到,表明其比活性炭吸附性弱,但更易再生。CNTY比活性炭的吸附性速率更快,遵循拟二级动力学模型。CNTY吸附DNT引起D、g常偏移,归因于CNTs与DNT间电子受体和供体效应。

关键词：碳纳米管纱 2,4-二硝基甲苯吸附 Freundlich吸附等温线新兴技术

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基于卷筒纸胶印的印品在线缺陷检测系统

中国印刷与包装研究 2009年第1期1卷 106-107页

作者： N.g. shankar N. Ravi Z.W. Zhong Euro Technology Pte Ltd Singapore ISDD UK Ltd UK School of MAE Nanyang Technological University Singapore

本文详细介绍了一种视觉系统,该系统可以实现对卷筒纸胶印过程中产生的印品缺陷进行检测和定位。具体来说,该系统能够对高速卷筒纸印刷进行实时监控,并且可在印刷过程中出现任何影响印品质量的故障(如结构缺陷、色彩偏差、漏字、墨点、... 详细信息

本文详细介绍了一种视觉系统,该系统可以实现对卷筒纸胶印过程中产生的印品缺陷进行检测和定位。具体来说,该系统能够对高速卷筒纸印刷进行实时监控,并且可在印刷过程中出现任何影响印品质量的故障(如结构缺陷、色彩偏差、漏字、墨点、墨杠等)时向操作人员发出警报。本文还介绍了机器视觉系统的硬件部分和用于彩色图像扫描及印品缺陷检测定位的图像处理算法。从本质上讲,该系统采用高速扫描算法检测图像的边缘和边界,利用线性和非线性的滤波器对动态大小、阈值和转换信息做进一步的分析。除了在实验室内进行实验以外,还建立了系统模型,系统模型可应用在卷筒纸印刷中,在真实条件下对模型的功能进行评价。将该系统安装在凹印机上进行实验,结果表明该机器视觉系统同样可以成功地对缺陷进行监控和检测。

关键词：卷筒纸胶印彩色图像卷筒纸印刷缺陷缺陷识别相关性

Kinetics of Anaerobic Digestion of Water Hyacinth,Poultry Litter,Cow Manure and Primary Sludge:A Comparative Study

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Kinetics of Anaerobic Digestion of Water Hyacinth,Poultry Li...

2012 2nd International Conference on Biotechnology and Environment Management

作者： Srinidhi Adiga Ramya R. shankar B.B. Jagadish H.Patil geetha C.R. R V College of Engineering Acharya Institute of Technology Sapthagiri College of Engineering

global depletion of energy supply due to the continuing over-utilization is a major problem of the present and future world *** is estimated that the fossil fuels will be exhausted in the next few *** today s energy demanding life style,there is always a need for exploring and exploiting new sources of energy which are renewable as well as *** digestion is a technology that utilizes various organic wastes（animal manure,energy crops and industrial wastes） to produce biofuel methane,which holds promise for the future while simultaneously addressing ecological and agrochemical *** the present study,kinetics of anaerobic digestion of dry water hyacinth,poultry litter,cow manure and primary sludge were undertaken in 250 ml biodigesters with 7% total solids and 60 days retention time and modified gompertz equation was tested for its *** kinetic parameters viz.,biogas yield potential（P）,the maximum biogas production rate（Rm） and the duration of lag phase（λ） were estimated for each *** digester fed with poultry litter produced maximum biogas（0.39 l（g VS）-1） and kinetic parameters P,Rm and λ were 0.3904 l（g VS）-1;0.0165 l（g VS）-1d-1 and 8.7498 days respectively.

关键词： Anaerobic digestion Biogas Modified gompertz equation Kinetic parameters Mesophilic range

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睾酮替代治疗

国际内科双语杂志（中英文） 2006年第6期6卷 4-6,36-39页

作者： Fred Wu U Srinivas-shankar 许岭翎（译）向红丁（校）英国曼彻斯特大学不详

雄激素与男性生殖道的分化、生长和功能及男性第二性征和性功能有关。循环中最主要的雄激素是睾酮，由睾丸中的Leydig细胞分泌。睾酮通过雄激素受体直接发挥作用，或者在某些特定的组织中（如前列腺），在5a还原酶的作用下，转变为更有... 详细信息

雄激素与男性生殖道的分化、生长和功能及男性第二性征和性功能有关。循环中最主要的雄激素是睾酮，由睾丸中的Leydig细胞分泌。睾酮通过雄激素受体直接发挥作用，或者在某些特定的组织中（如前列腺），在5a还原酶的作用下，转变为更有活性的代谢物去氢睾酮（DHT）而发挥其生物学效应。睾酮也可以芳香化生成雌二醇，然后通过雌激素受体（如骨）发挥其作用。

关键词：睾酮替代治疗雄激素受体 5a还原酶生物学效应雌激素受体第二性征细胞分泌生殖道前列腺代谢物

肝脏肿瘤经皮冰冻消融术后生物化学和血液学的变化:48次治疗报告

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国际医学放射学杂志 2008年第5期31卷 397-398页

作者： R.T. Nair S.g. Silverman K. Tuncali N.A. Obuchowski E. van Sonnenberg S. shankar. 叶锦棠（译）唐光健（校） Division of Abdominal Imaging and Intervention Department of Radiology Brigham and Women＇s Hospital Harvard Medical School Boston USA. 不详

目的回顾分析肝脏肿瘤经皮冰冻消融术后实验室化验值出现异常的频度和严重程度，估计实验室化验值与肿瘤及消融体积的相关性。方法这项符合HIPAA要求的研究得到了伦理委员会的批准，可免除知情同意书。对39例病人（男性18例，女性21例... 详细信息

目的回顾分析肝脏肿瘤经皮冰冻消融术后实验室化验值出现异常的频度和严重程度，估计实验室化验值与肿瘤及消融体积的相关性。方法这项符合HIPAA要求的研究得到了伦理委员会的批准，可免除知情同意书。对39例病人（男性18例，女性21例；年龄29—86岁）的65个肝脏肿瘤（62个转移瘤和3个肝细胞癌）进行了48次MRI引导下经皮冰冻消融术，回顾分析其生物化学和血液学方面的实验室检查数据。分析术前基础化验值与术后0-6h、1～2周化验值相对于肿瘤和消融带边界体积的变化。肿瘤与消融边界体积用一般性估计方程计算。

关键词：肝脏肿瘤生物化学消融术血液学治疗报告冰冻伦理委员会 HIPAA

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PNAS:维生素A和C如何擦除细胞记忆?

现代生物医学进展 2017年第4期17卷 I0003-I0003页

作者： Timothy Alexander Hore[a],[b], Ferdinand von Meyenn[a], Mirunalini Ravichandran[c], Martin Bachman[d],[e] gabriella Ficz[f] David Oxley[g] Fátima Santos[a] shankar Balasubramanian[d],[e] Tomasz P. Jurkowski[c], Wolf Reik[a],[h], [a]Epigenetics Programme Babraham Institute Cambridge CB22 3AT United Kingdom [b]Department of Anatomy University of Otago Dunedin 9016 New Zealand [c]Institute of Biochemistry University of Stuttgart 70569 Stuttgart Germany [d]Department of Chemistry University of Cambridge Cambridge CB2 1EW United Kingdom [e]Cancer Research UK Cambridge Institute University of Cambridge Cambridge CB2 0RE United Kingdom [f]Barts Cancer Institute Queen Mary University of London London EC1M 6BQ United Kingdom [g]Mass Spectrometry Facility Babraham Institute Cambridge CB22 3AT United Kingdom [h]Wellcome Trust Sanger Institute Hinxton CB10 1SA United Kingdom

维生素A和C不只是对我们的健康有益，其还会影响到机体的DNA，日前一项刊登于国际杂志PNAS上的研究论文中，来自巴布拉汉研究所（Babraham Institute）等机构的研究人员通过研究揭示了维生素A和C如何修饰细胞的表观遗传记忆。相关研究... 详细信息

维生素A和C不只是对我们的健康有益，其还会影响到机体的DNA，日前一项刊登于国际杂志PNAS上的研究论文中，来自巴布拉汉研究所（Babraham Institute）等机构的研究人员通过研究揭示了维生素A和C如何修饰细胞的表观遗传记忆。相关研究或为后期研究者们开发新型再生医学疗法或者对细胞重编程提供一定的思路。

关键词：维生素A 细胞记忆擦除研究论文表观遗传研究人员再生医学

Qualitative and Quantitative Characterization of Wood Fibers of Shrubs and Tree Species of the Tamaulipan Thorn Scrub, Northeastern Mexico and Its Possible Relation to Wood Quality and Utilization

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American Journal of Plant Sciences 2016年第7期7卷 1046-1057页

作者： Ratikanta Maiti Humberto g. Rodriguez Aruna Kumari Departamento de Quimica y Biologia Universidad de las Americas Santa Catarina Martir Mexico Facultad de CienciasForestales Universidad Autonoma de Nuevo Leon Linares Mexico Agricultural College Jaya Shankar Telangana State Agricultural University Jagtial India

The present study was undertaken to determine the variability in fiber cell morphology and its length among wood species of the Tamaulipan Thorn Scrub, Northeastern Mexico, used for various uses such as timber for furniture, fence, post, firewood and sources of forage. The results reveal large variability in fiber cell morphology and fiber cell dimensions. The species are classified on the basis of its fiber cell morphology and fiber cell length and recommended for their possible utilization for different purposes. Wood having fibre cells with broad lumen and thin wall could be suitable for the manufacture of paper documented in the literature viz. Acacia farnesciana, Caesalpinia mexicana, Cordia boisiieri, Diospyros palmeri, Forestieria angustifolia, Morus celtifolia, Prosopis laevigata. This technique can be used in preliminary screening of woody species for its utilization for different purposes. Further studies are needed to confirm.

关键词： Wood Fiber Cells Characterization Variability Woody Species Wood Quality Tamualipan Thorn Scrub