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浙江工业大学学报（社会科学版） 2008年第2期7卷 186-189页

作者：於建明林洁彭国军王臻浙江工业大学建筑工程学院浙江杭州310032

在高度重视高等教育质量和大力提倡终身教育的高等教育大众化的社会背景下,回归教育的价值日益显现出来,逐渐被社会企业与高校所认同。本文在分析回归教育的基本概念与内在价值的基础上,对现阶段高校毕业生回归教育的实现途径进行了探讨。

关键词：高校毕业生回归教育内在价值实现途径

The therapeutic effects of dihydrolycorine on focal cerebral ischemiareperfusion injury in rats

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The therapeutic effects of dihydrolycorine on focal cerebral...

中国神经科学学会第四次会员代表大会暨第八届全国学术会议

作者： Xin-Rong GONG~1,Guang-Qing YU~2,Long-Shun YU~1,Xing-Lian LAN~1,Long-Rui PAN~1,Shi-Qin JIANG~(3,*) 1 Department of Pharmacology,Yunyang Medical college,Shiyan,442000 2 Center for Disease Control and Prevention in Baoan District of Shenzhen,Shenzhen,518101 3 Department of Pharmacy,Maternal and Child Health Hospital in Futian District of Shenzhen,Shenzhen,518026

＜正＞Objective To investigate the therapeutic effects of dihydrolycorine on focal cerebral ischemia-reperfusion injury in *** The middle cerebral artery（MCA） on one side was occluded by inserting a nylon suture through the internal carotid artery for 1 h,following reperfusion for 24 h by withdrawing the ***（10,20,40 mg/kg） was given respectively at the beginning of the cerebral ischemia immediately,and 11 h and 23 h after reperfusion through intraperitoneal *** 3 h and 24 h after reperfusion,the neurological outcome was evaluated by the Longa’s method. At 24 h after reperfusion,the infarct volume was assessed by TTC staining and the cerebral water content was measured by dry-weight *** 24 h after reperfusion,the brains were rapidly *** effect of DL on the migration of neutrophil was evaluated by measuring the activity of myeloperoxidase（MPO）.Results After 1 h ischemia and 3 h reperfusion,DL significantly ameliorated the neurological deficit（P＜0.05 vs model group）.After 1 h ischemia and 24 h reperfusion,DL（5,10 mg/kg） still significantly ameliorated the neurological deficit（P＜0.05 vs model group）.After 1 h ischemia and 24 h reperfusion,DL reduced the cerebral infarct volume and water content（P＜0.05 vs model group）.And the effects of DL（20,40 mg/kg） were better than those of DL（10mg/kg）（F＜0.05）.After treated with DL,the activity of MPO were significantly reduced compared with that in model group（P＜0.05）.Conclusion Treated with DL after cerebral ischemia-reperfusion,DL could obviously alleviate the neurological symptoms,reduce the infract volume and water contents,reduced the activity of *** results indicated that dihydrolycorine has obviously therapeutic effects on cerebral ischemia-reperfusion injury in rats.

关键词： dihydrolycorine focal cerebral ischemia-reperfusion myeloperoxidase

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BP算法应用于智能传感器的数据处理

三峡大学学报（自然科学版） 2002年第4期24卷 351-354页

作者：李力田爱玲高虹亮三峡大学机械与材料学院湖北宜昌443002 西安工业学院陕西西安710032

利用BP算法具有的非线性映射能力对传感器标定数据进行输入-输出特性的反非线性逼近,将其作为智能传感器系统的非线性校正软件,使传感器在该软件的支持下提高测量精度.用传感器实验数据通过训练的网络,测量相对误差由原来的约6.66％下降... 详细信息

利用BP算法具有的非线性映射能力对传感器标定数据进行输入-输出特性的反非线性逼近,将其作为智能传感器系统的非线性校正软件,使传感器在该软件的支持下提高测量精度.用传感器实验数据通过训练的网络,测量相对误差由原来的约6.66％下降至O.98％.

关键词： BP算法智能传感器数据处理神经网络

光谱法研究2-环己氨基噻吩并[2,3-d]嘧啶-4(3H)-酮与牛血清白蛋白的相互作用

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咸宁学院学报（医学版） 2007年第5期21卷 391-394页

作者：孙绍发毛艳平刘洁李为娇孙亮咸宁学院化学与生命科学系湖北咸宁437000

目的为新型噻吩并嘧啶的开发与应用提供重要信息。方法应用荧光光谱、紫外可见光谱方法研究了2-环己氨基噻吩并[2,3-d]嘧啶-4(3H)-酮(HJA)与牛血清白蛋白(BSA)的相互作用。结果HJA能强烈猝灭BSA的荧光强度,其荧光猝灭机理为动态猝灭。... 详细信息

目的为新型噻吩并嘧啶的开发与应用提供重要信息。方法应用荧光光谱、紫外可见光谱方法研究了2-环己氨基噻吩并[2,3-d]嘧啶-4(3H)-酮(HJA)与牛血清白蛋白(BSA)的相互作用。结果HJA能强烈猝灭BSA的荧光强度,其荧光猝灭机理为动态猝灭。在此基础上计算了二者相互作用的结合常数、结合位点数及热力学参数等。结论HJA分子与BSA分子以摩尔比1∶1结合,其结合反应主要是熵驱动,主要作用力是疏水力。

关键词： 2-环己氨基噻吩并[2 3-d]嘧啶-4(3H)-酮牛血清白蛋白荧光猝灭热力学参数

PAHs Emission during Sewage Sludge Combustion in a Drop Tube Furnace

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PAHs Emission during Sewage Sludge Combustion in a Drop Tube...

2012年环境污染与大众健康学术会议

作者： Yuqi Li 1 , Jun Han 1 , Linbo Qin 1 , Zhiqiang Tu 1 , Wenjun Zhang 1 , Wei Ye 1 , Wangsheng Chen 2 1. Hubei Key Laboratory of Coal Conversion and New Materials Wuhan University of Science and Technology, Wuhan, P.R.China 2. college of Resources and Environment Engineering Wuhan university of Science and Technology Wuhan, P.R.China

The emission characteristic of Polycyclic Aromatic Hydrocarbons （PAHs） during sewage sludge combustion was investigated in a laboratory-scale drop tube furnace at a temperatures range of 950-1250 0 C. The experimental results demonstrated that FluA, BbF, BaP and DbA are dominated in flue gas. Meanwhile, the four-ring, five-ring PAHs and the total PAHs emission in flue gas during sewage sludge combustion were firstly increased and then decreased at temperature ranging from 950 to 1250 0 C. In addition, it was also found that the five-ring PAHs were the main contribution for the toxic equivalent （TEQ） concentration. The five-ring PAHs TEQ concentration accounted for more than 92.0% of total PAHs TEQ concentrations.

关键词： Sewage sludge combustion drop tube furnace PAHs

Induction of bone marrow stromal cells into neuron-like cells by vascular endothelial growth factor

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Induction of bone marrow stromal cells into neuron-like cell...

中国神经科学学会第四次会员代表大会暨第八届全国学术会议

作者： Qiao-Yun LIU Li YI Jin-Ling HAN Ye jING Fang-Ting ZHANG Guang-Hui CUI 1 Medical college of Shantou University Shantou 515041 China. 2 Department of Neurology Peking University Shenzhen Hospital Shenzhen 518036 China 3 Central Laboratory Peking University Shenzhen Hospital Shenzhen 518036 China 4 Laboratory of Male Reproductive Medicine Peking University Shenzhen Hospital Shenzhen 518036 China

＜正＞Objective To investigate the possibility of induction of bone marrow stromal cells（BMSCs） into neuron-like cells by vascular endothelial growth factor（VEGF） in vitro,so as to provide experimental basis for the treatment of brain injury by cell transplantation and *** Bone marrow stromal cells were harvested from young Sprague-Dawley rats and cultured in DMEM/F12 suppplemented with 10%fetal bovine *** BMSCs were passaged 3 times and characterized by flow *** BMSCs were pre-induced by basic fibroblast growth factor（b-FGF, 10ng/ml） for 24h,then they were treated with different concentrations of vascular endothelial growth factor（VEGF）,which was used to induce BMSCs into neuron-like *** experiment was separated into four groups:Group A（contains 5ng/ mlVEGF）,Group B（contains 10ng/miVEGF）,Group C（contains 20ng/mlVEGF） and Group D served as a control group never adding *** contrast microscope was used to observe the differentiation of BMSCs daily,and the total number of neuron-like cells in 20 random fields（×200） was count at 3 and 10 days after *** technique was used to identify the differentiated BMSCs with neuron specific enolase（NSE）.Result The cultured BMSCs were CD90 positive and CD45 negative on flow *** 3 days after induction,some BMSCs in groups A～C were observed to change the shapes:cell bodies appeared refractile,cone-like,or spherical with primary and secondary *** 10 days after induction,the number of the cells which assumed neuronal morphology increased in groups A～*** in morphology of a few of BMSCs in group D was *** were the most neuron-like cells in group B,P＜0.05 for group B versus other *** were the fewest neuron-like cells in group D,P＜0.05 for group D versus other *** the neuron-like cells at 10 days after induction was more than those at 3 days after induction in all the groups,P＜0.05 for the numbers of the neuron-like ce

关键词： vascular endothelial growth factor bone marrow stromal cells neuron-like cells cell differentiation

Influence of the MFB stimulation on the mesencephalic dopaminergic system

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Influence of the MFB stimulation on the mesencephalic dopami...

中国神经科学学会第四次会员代表大会暨第八届全国学术会议

作者： Qian LI~(1,2),Shao-Min ZHANG~(1,2,*),Yi YU~(1,2),Huai-Jian ZHANG~(1,2),Qiao-Sheng ZHANG~(1,2),Xiao-Xiang ZHENG~(1,2) 1 Qiushi Academy for Advanced Studies,Zhejiang University,Hangzhou 310027,China 2 college of Biomedical Engineering and Instrument Science,Zhejiang University,Hangzhou 310027,China

＜正＞Objective As the main component of brain’s reward center,the electrical stimulation of the medial forebrain bundle（MFB） leads to the activation of the mesocorticolimbic dopaminergic *** effect elicits the intense intracranial self-stimulation（ICSS）,which strengthens the rats to perform a series of reward-motivated reinforcement *** the MFB is assembled by the axon bundles of dopaminergic neurons both in the mesocorticolimbic pathway and nigrostriatal pathway,the present study aims to explore that the MFB stimulation not only activates the brain’s reward center,but also impacts the nigrostriatal pathway,which participates the cortico-basal ganglia *** 18 adult male Sprague-Dawley rats were randomly divided into GroupsⅠ,ⅡandⅢ.Group I:stimulating electrode was implanted into hibateral MFB（Aβ:-3.60;ML:±1.80;DV:+9.20）.By using an eight-arm radial maze,the rat’s preferable turning direction was recorded when the stimulation was delivered in the arm exit,which reliably reflected the different effects of MFB stimulation on the locomotor behavior of bilateral *** II:stimulating electrode and single-channel local field potential（LFP） recording electrode were implanted into the bilateral MFB and the primary cerebral cortex（M1, Aβ:+2.50;ML:±3.00;DV:+1.20）.After recording the Ml-LFPs pre and post stimulation,wavelet packet transform（WPT） was applied to make time-frequency spectrum ***Ⅲ:stimulating electrode and 7-channel spike recording bundle were implanted into the unilateral MFB and the ipsilateral entopeduncular nucleus（EP,Aβ:-2.40;ML:±2.80;DV: +7.60）.After getting the EP-spikes pre and post stimulation,detecting and sorting algorithm helped to draw each neuron’s ***-Stimulus Time Histogram（PSTH） and Inter-Spike Intervals（ISIs） were plotted to decode the firing patterns of the EP-GABAergic ***（1）Unilateral MFB stimulation caused a striking asymmetry in the rat’s locomotor *** contralateral turning w

关键词： medical forebrain bundle mesocorticolimbic dopaminergic pathway nigrostriatal pathway basal ganglia extrapyramidal system

急性CO中毒后迟发性脑病神经元特异性烯醇化酶测定的临床意义

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上海医学检验杂志 2002年第3期17卷 154-156页

作者：张秀明万光霞顾仁骏郭新胜沈琪琳周伟强郭杰新乡医学院第二附属医院河南453002 新乡市第二人民医院河南453000

目的　探讨急性CO中毒后迟发性脑病 (DEACMP)患者脑脊液 (CSF)和血清神经元特异性烯酶化酶(NSE)的变化及临床意义。方法　对 49例DEACMP患者均在急性期入院 3d内抽取CSF和血标本进行NSE测定 ,其中 34例于治疗 30d后再次采取标本复查 ,... 详细信息

目的　探讨急性CO中毒后迟发性脑病 (DEACMP)患者脑脊液 (CSF)和血清神经元特异性烯酶化酶(NSE)的变化及临床意义。方法　对 49例DEACMP患者均在急性期入院 3d内抽取CSF和血标本进行NSE测定 ,其中 34例于治疗 30d后再次采取标本复查 ,对比分析治疗前后NSE的变化。结果　患者组急性期CSF和血清NSE含量较对照组明显增高 (P 0 .0 5 ) ;患者组CSF和血清NSE呈明显正相关 (r =0 .46 14,P <0 .0 0 1)。结论　CSF和血清NSE测定可作为DEACMP诊断和病情判断的有效指标。

关键词：迟发性脑病测定临床意义神经元特异性烯醇化酶急性一氧化碳中毒

The major histocompatibility complex genes were associated with the painrelated responses induced by formalin between DA and congenic DA.1U rats

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The major histocompatibility complex genes were associated w...

中国神经科学学会第四次会员代表大会暨第八届全国学术会议

作者： Yuan GUO~1,Fan-Rong YAO~1,Dong-Yuan CAO~(1,2),Rong LUO~1,Li LI~1,Shao-Jie MA~1,Hui-Sheng WANG~1,Yan ZHAO~(1*) 1 Department of Physiology and Pathophysiology,Xi''an Jiaotong University School of Medicine,Xi''an,710061,China 2 Palmer Center for Chiropractic Research,Palmer college of Chiropractic,741 Brady Street,Davenport,I A 52803, USA

＜正＞Objective Some studies on humans,as well as laboratory animals suggested that there exist significant differences of pain-related response between *** in genetic influences on pain-related responses has increased dramatically in recent *** the present study,the role of major histocompability complex（MHC） genes in the pain-related responses induced by formalin was investigated in Dark-Agouti（DA） rats and a novel congenic DA.1U rats, whose genetic background is the same as DA rats except MHC *** Behaviors were simultaneously analyzed for lh and the specific nociceptive scores were measured using the method described by Dubuisson and Dennis（1977） following intraplantar injection of formalin（2.5%,50μL）.The discharge rates of single afferent fiber innervating the planta of hindpaw were recorded from dorsal root to investigate the response induced by *** methods were used to observe the expression of RT1B,which represented the DQ region of MHC II genes,in L4/5 spinal cord in the two rat strains to analyze the role of MHC genes in the pain-related ***（1） Biophasic pain-related responses were observed in the two strains following the intraplanta injection of *** specific nociceptive scores of DA rats in the two phases were significantly higher than those of DA.1U rats（P＜0.01）.（2） Electrophysiological results showed that the discharge rates of C and A8 fibers increased significantly in the two strains,and the mean net change of discharge rates of DA rats were significantly higher than that of DA.1U rats（P＜0.05）.（3） The expressions of RT1B were mainly observed in laminaeⅠ-Ⅱof L4/5 spinal cord in two *** expressions of RT1B in DA rats were significantly higher than those in DA.1U rats before and after injection of formahn（P＜0.05）.All these results suggested that DQ region of MHCⅡgenes may be involved in the pain-related response induced by formalin,which may provide further evidence for

关键词： major histocompability complex pain-related response individual difference RT1B

苏州电影放映的现代化研究——以公园电影院为例

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苏州教育学院学报 2011年第4期28卷 24-29页

作者：李斌曹燕宁苏州科技学院人文学院苏州工艺美术职业技术学院组织人事处

随着20世纪初上海现代化的扩散,苏州凭借区位优势,已生发出现代质素,与上海建构起智力资源互通、文化市场互融、文化产业互促的关联。公园电影院的创办正是上海现代化向沪外周边地区扩散以及苏州接受上海现代化影响的证明,它的关闭也说... 详细信息

随着20世纪初上海现代化的扩散,苏州凭借区位优势,已生发出现代质素,与上海建构起智力资源互通、文化市场互融、文化产业互促的关联。公园电影院的创办正是上海现代化向沪外周边地区扩散以及苏州接受上海现代化影响的证明,它的关闭也说明现代化的扩散受到经济、文化和政治多方面因素的影响,是一个曲折前行的过程。

关键词：公园电影院沪外电影放映现代化