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Anti-skin aging effects and bioavailability of collagen tripeptide and elastin peptide formulations in young and middle-aged women

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Journal of dermatologic science and cosmetic technology

Journal of dermatologic science and cosmetic technology 2024年第2期1卷 26-37页

作者： shan lu Silu Zhang Yun Wang Jiayi Ni Tiantian Zhao Guoxun Xiao Wonderlab Innovation Centre for Healthcare Shenzhen Porshealth Bioengineering CoLtd.Shenzhen 518116China Sericulture&Agri-food Research Institute Guangdong Academy of Agricultural Sciences Key Laboratory of Functional FoodsMinistry of Agriculture and Rural affairsGuangdong Key Laboratory of Agricultural Products ProcessingGuangzhouGuangdong 510610China Department of Dermatology Shanghai Ninth People‘s HospitalShanghai Jiao Tong University School of MedicineShanghai 200125China Sprim(China)Consulting Co.Ltd. Shanghai 201201China e Department of Food Science Rutgers UniversityNew BrunswickNJ 08901United States

Background:Collagen peptides(CP),including tripeptides and elastin peptides(EP),are known for their in vitro and in vivo anti-skin aging *** positive results in animal models,the combination effects of CP and EP and the bioavailability of CP in human studies,particularly in young and middle-aged women,remain ***:To evaluate the effects of an orally administered collagen drink combining CP and EP on the skin health of young and middle-aged *** and Methods:A single-center,randomized,double-blind,parallel-controlled trial was conducted,utilizing the WONDERLABR fish collagen tripeptide *** consumed the drink over an 8-week ***:Compared to the placebo group,the collagen drink group showed significant improvements in skin hydration(39.19%increase),transepidermal water loss(33.45%decrease),skin elasticity(25.37%increase),dermal collagen content(21.64%increase),pore size(7.94%decrease),wrinkle length(18.09%decrease),skin smoothness(2.85%improvement),and skin roughness(15.32%decrease).Overall pore volume decreased by 60%,and visual assessments indicated a decrease in skin luminosity by 15.20%and smoothness index by 22.55%.Mass spectrometry demonstrated a significant increase in collagen efficacy components,including blood pH and GPH levels(Plusion:The study confirmed the combination nourishing and anti-skin aging effects of EP and CP on the skin of young and middle-aged women,demonstrating significant improvements in various skin parameters and good bioavailability of collagen peptides.

关键词： Collagen tripeptides Elastin peptides Anti-aging Skin protection Peptide absorption

Effect and Safety of Herbal Medicine Foot Baths in Patients with Diabetic Peripheral Neuropathy:A Multicenter Double-Blind Randomized Controlled Trial

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Chinese Journal of Integrative Medicine 2024年第3期30卷 195-202页

作者： HUANG Hao-yue LIN Yu-ping WEI Hua FU Yu ZHOU Yue-hong FANG Zhao-hui QIU Xiao-tang WANG Mei LI Qing-bo LI shan-shan WANG Shi-dong DAI Fang LIU Zhen-jie ZHAO Ling WEN Jian-xuan WU Li-yan ZENG Hui-yan ZHANG Jin-ming lu Qi-yun HE Liu SONG Wei SUN lu luO lu-lu HE Jia-li XIE Wen-wen LIANG Qing-shun HUANG Yuan ZHU Sheng-ling LONG Jie-er GAO Zhi-juan WEN Ze-huai LI Chun-ji OUYANG Wen-wei LI Geng WU Ming-hui LI An-xiang HUANG Jin-zhu Sanjoy K Paul TANG Xian-yu FAN Guan-jie Department of Endocrinology Guangdong Provincial Hospital of Chinese MedicineGuangzhou510120China The Second Clinical College of Guangzhou University of Chinese Medicine Guangzhou510120China Department of Endocrinology The Second Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou510120China Guangdong Provincial Academy of Chinese Medical Sciences Guangzhou510120China Department of Endocrinology The First Affiliated Hospital of Henan University of Chinese MedicineZhengzhou450000China Department of Endocrinology Liuyang Hospital of Chinese MedicineChangsha410000China Department of Endocrinology The First Affiliated Hospital of Anhui University of Chinese MedicineHefei230000China Department of Endocrinology Hainan Provincial Hospital of Traditional Chinese MedicineHaikou570100China Department of Endocrinology The Affiliated Hospital of Liaoning University of Traditional Chinese MedicineShenyang110000China Department of Geriatric Luoyang No.1 Hospital of Traditional Chinese MedicineLuoyangHenan Province471000China Department of Endocrinology The Second Affiliated Hospital of Guizhou University of Traditional Chinese MedicineGuiyang550000China Department of Endocrinology Beijing University of Chinese Medicine Affiliated Dongzhimen HospitalBeijing100000China Department of Endocrinology The First Affiliated Hospital of Guizhou University of Traditional Chinese MedicineGuiyang550000China Melbourne EpiCentre The University of Melbourne and Melbourne HealthMelbourne3013Australia

Objective:To evaluate the effect and safety of foot baths with Tangbi Waixi Decoction(TW)in treating patients with diabetic peripheral neuropathy(DPN).Methods:It is a multicenter double-blinded randomized controlled *** with DPN were recruited between November 18,2016 and May 30,2018 from 8 hospitals in *** patients received basic treatments for glycemic *** received foot baths with TW herbal granules either 66.9 g(intervention group)or 6.69 g(control group)for 30 min once a day for 2 weeks and followed by a 2-week rest,as a therapeutic *** the Toronto Clinical Scoring System total score(TCSS-TS)6 points,the patients received a total of 3 therapeutic courses(for 12 weeks)and were followed up for 12 *** primary outcome was change in TCSS-TS score at 12 and 24 *** outcomes included changes in bilateral motor nerve conduction velocity(MNCV)and sensory nerve conduction velocity(SNCV)of the median and common peroneal *** was also ***:Totally 632 patients were enrolled,and 317 and 315 were randomized to the intervention and control groups,*** the 12-week intervention,patients in both groups showed significant declines in TCSSTS scores,and significant increases in MNCV and SNCV of the median and common peroneal nerves compared with pre-treatment(P0.05),and no serious adverse event was related with ***:Treatment of TW foot baths was safe and significantly benefitted patients with DPN.A low dose of TW appeared to be more effective than a high dose.(Registry *** CTR-IOR-16009331)

关键词： diabetic peripheral neuropathy herbal medicine foot baths Chinese medicine randomized controlled trial Tangbi Waixi Decoction

生态位视域下世界一流大学的战略选择及其启示

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黑龙江高教研究 2024年第9期42卷 36-41页

作者：薛珊刘路湖北师范大学湖北黄石435002 江苏大学江苏镇江212013

生态位理论为世界一流大学战略选择提供了新的分析视角。世界一流大学战略选择的要义在于立足生态环境确定生态位,建立大学与环境的适应性机制,依据生态位目标配置战略资源。其战略选择具体体现为共生发展、协同发展、跨越式发展、错位... 详细信息

生态位理论为世界一流大学战略选择提供了新的分析视角。世界一流大学战略选择的要义在于立足生态环境确定生态位,建立大学与环境的适应性机制,依据生态位目标配置战略资源。其战略选择具体体现为共生发展、协同发展、跨越式发展、错位发展等战略。对“双一流”建设的启示有:更新战略选择理念,准确定位生态位;优化战略实施策略,采取适宜的生态位战略;拓展生态位宽度,持续跃升生态位。

关键词：生态位世界一流大学战略选择

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老年人肌肉减少症与心血管代谢疾病研究进展

中华流行病学杂志 2024年第6期45卷 879-885页

作者：陆治名单广良中国医学科学院基础医学研究所/北京协和医学院基础学院流行病与卫生统计学系北京100005 重大疾病共性机制研究全国重点实验室北京100005

肌肉减少症和心血管代谢疾病已成为影响老年人健康和生活质量的重要公共卫生问题。预防肌肉减少症发生对心血管代谢疾病的防治具有重要意义。本文就老年人肌肉减少症诊断标准、肌肉减少症与心血管代谢疾病的关系及可能机制进行综述,为... 详细信息

肌肉减少症和心血管代谢疾病已成为影响老年人健康和生活质量的重要公共卫生问题。预防肌肉减少症发生对心血管代谢疾病的防治具有重要意义。本文就老年人肌肉减少症诊断标准、肌肉减少症与心血管代谢疾病的关系及可能机制进行综述,为肌肉减少症合并心血管代谢疾病的防控提供支持。

关键词：肌肉减少症老年人心血管代谢疾病

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分体式太阳能PVT热泵系统试验运行性能分析

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动力工程学报 2024年第10期44卷 1574-1581页

作者：陆王琳李政姜山上海发电设备成套设计研究院有限责任公司上海200240 上海交通大学机械与动力工程学院太阳能发电与制冷教育部工程研究中心上海200240

在既有光伏组件的基础上,安装集热背板形成分体式PVT组件,搭建分体式PVT热泵系统试验台,在晴天和多云典型日2种工况下进行系统运行性能试验,将水箱内的水从常温加热到60℃。试验结果表明,在晴天和多云典型日下,系统平均COP分别为4.11和4... 详细信息

在既有光伏组件的基础上,安装集热背板形成分体式PVT组件,搭建分体式PVT热泵系统试验台,在晴天和多云典型日2种工况下进行系统运行性能试验,将水箱内的水从常温加热到60℃。试验结果表明,在晴天和多云典型日下,系统平均COP分别为4.11和4.20,均高于相同工况下的空气源热泵;最大发电效率分别为13.2%和19.9%,PVT组件表面温度分布均低于40℃,有明显的降温提效作用;平均得热因子分别为48%和71%,无量纲压力损失系数保持在0.030~0.047,均流性较好。

关键词：光伏光热热泵分体式既有光伏

Recent progress and strategies of cathodes toward polysulfides shuttle restriction for lithium-sulfur batteries

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Rare Metals 2024年第9期43卷 4132-4161页

作者： Xing-You Rao Shuang-Fei Xiang Jian Zhou Zhen Zhang Xiang-Yu Xu Yuan-Yuan Xu Xin-Chi Zhou Zheng-Dao Pan Su-Chong Tan Shi-Xing Dong Zhou-lu Wang Yu-Tong Wu Yun-Lei Zhou Xiang Liu Yi Zhang shan Jiang School of Energy Sciences and Engineering Nanjing Tech University School of Materials Science and Engineering and Institute of Smart Fiber Materials Zhejiang Sci-Tech University JiangSu Sailboat Petrochemical Co. Ltd Hangzhou Institute of Technology Xidian University

Lithium-sulfur batteries(LSBs) have already developed into one of the most promising new-generation high-energy density electrochemical energy storage systems with outstanding features including high-energy density, low cost, and environmental friendliness. However, the development and commercialization path of LSBs still presents significant limitations and challenges, particularly the notorious shuttle effect triggered by soluble longchain lithium polysulfides(LiPSs), which inevitably leads to low utilization of cathode active sulfur and high battery capacity degradation, short cycle life, etc. Substantial research efforts have been conducted to develop various sulfur host materials capable of effectively restricting the shuttle effect. This review firstly introduces the fundamental electrochemical aspects of LSBs, followed by a comprehensive analysis of the mechanism underlying the shuttle effect in Li–S batteries and its profound influence on various battery components as well as the overall battery performance. Subsequently, recent advances and strategies are systematically reviewed, including physical confinement, chemisorption, and catalytic conversion of sulfur hosts for restricting LiPSs shuttle effects. The interplay mechanisms of sulfur hosts and LiPSs are discussed in detail and the structural advantages of different host materials are highlighted. Furthermore, key insights for the rational design of advanced host materials for LSBs are provided, and the upcoming challenges and the prospects for sulfur host materials in lithium-sulfur batteries are also explored.

关键词： Host Lithium-sulfur batteries Polysulfides Shuttle effect

米糠提取物在食品及健康领域中的应用研究进展

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食品科学 2024年第17期45卷 287-295页

作者：冯俊然洪滨山珊袁迪张珊宋岩李波卢淑雯任传英黑龙江省农业科学院食品加工研究所黑龙江省食品加工重点实验室黑龙江省全谷物营养食品工程技术研究中心黑龙江哈尔滨150086 黑龙江省农业科学院园艺分院黑龙江哈尔滨150069

米糠提取物(rice bran extract,RBE)是从米糠中分离得到的营养物质,由于其含有大量的生物活性成分,具有良好的抗氧化能力,在食品及健康领域能发挥独特优势。此外,所用的米糠原料和制备方法不同,所得到的生物活性化合物的种类和含量不同... 详细信息

米糠提取物(rice bran extract,RBE)是从米糠中分离得到的营养物质,由于其含有大量的生物活性成分,具有良好的抗氧化能力,在食品及健康领域能发挥独特优势。此外,所用的米糠原料和制备方法不同,所得到的生物活性化合物的种类和含量不同。本文结合近年来RBE的相关研究,系统论述其常用制备方法、功能特性及应用现状,并提出目前研究所存在的不足,旨在探讨其在食品及健康领域中的潜在应用价值及未来研究热点,以期为米糠精深加工提供参考。

关键词：米糠提取物抗氧化能力食品及健康领域生物活性化合物

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化学教育中学习轨迹的概念及内涵分析

化学教育（中英文） 2024年第9期45卷 2-8页

作者：刘祎玮卢姗姗山东师范大学化学化工与材料科学学院山东济南250014

学习轨迹是特定教学活动下学生学习心理的轨迹,有利于教师掌握学情从而实现以学生为中心的教学。在国内外相关文献基础上,首先明确学习轨迹是学生在由教学引起的关键事件上认知、情感、动机等与学习有关的动态心理过程的总和;提炼出学... 详细信息

学习轨迹是特定教学活动下学生学习心理的轨迹,有利于教师掌握学情从而实现以学生为中心的教学。在国内外相关文献基础上,首先明确学习轨迹是学生在由教学引起的关键事件上认知、情感、动机等与学习有关的动态心理过程的总和;提炼出学习轨迹的3个特征,分别为特异性、序列性和结构化;之后介绍了学习轨迹的探查、教学与测评以及教师专业发展等研究领域;最后从教学设计和有效教学2个方面探讨了学习轨迹的研究价值,为化学教育研究者了解该领域提供一些参考。

关键词：学习轨迹学习进阶教师专业化

技术创新对能源利用效率影响的空间效应与机制——基于中国278个地级以上城市的面板数据

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中南大学学报（社会科学版） 2024年第2期30卷 101-113页

作者：陆杉李雯湖南工商大学资源环境学院湖南长沙410205 碳中和与智慧能源湖南省重点实验室湖南长沙410205 湖南工商大学经济与贸易学院湖南长沙410205

基于空间视角,利用2008—2019年中国278个地级市的面板数据,运用空间杜宾模型和面板门槛模型,实证检验技术创新对能源效率的直接效应、间接效应及门槛效应。研究表明:技术创新不仅有利于提升本城市的能源利用效率,还会通过溢出效应提升... 详细信息

基于空间视角,利用2008—2019年中国278个地级市的面板数据,运用空间杜宾模型和面板门槛模型,实证检验技术创新对能源效率的直接效应、间接效应及门槛效应。研究表明:技术创新不仅有利于提升本城市的能源利用效率,还会通过溢出效应提升邻近城市的能源利用效率,存在显著的空间溢出效应,并且技术创新对能源利用效率的影响因城市区位和技术创新水平不同而存在异质性。绿色技术进步和产业结构升级在技术创新提升能源利用效率中发挥中介作用,技术创新通过提高绿色技术进步和促进产业结构升级来提升能源利用效率。当经济发展水平较低时,技术创新对能源利用效率有明显的抑制作用;当经济发展水平越过一定临界值后,技术创新能显著提升能源利用效率。

关键词：技术创新能源利用效率经济发展水平空间杜宾模型

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