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Comparative Study of Visual and Instrumental Analyses of Shade Selection

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Journal of Wuhan University of Technology(Materials Science) 2010年第1期25卷 62-67页

作者： Jee-Ha Choi ju-Mi Park Seung-Geun Ahn Kwang-Yeob Song Min-ho Lee Jae-Youn jung Xinyu Wang Department of Prosthodontics and Institute of Oral Bioscience School of Dentistry Chonbuk National University Jeonju Republic of Korea Department of Dental Biomaterials and Institute of Oral Bioscience School of Dentistry Chonbuk National University Jeonju Republic of Korea Division of Mechanical & Aerospace System Engineering and RCIT Chonbuk National University Jeonju Republic of Korea Biomedical Materials and Engineering Research Center Wuhan University of Technology Wuhan 430070 China

The difference between visual and instrumental analyses of a shade selection on natural teeth was investigated. With visual analysis, five prosthodontist examined the middle third of the unrestored maxillary right central incisor of a patient using VITAPEN classical and Vita Toothguide 3D-MASTER tooth shade guide. In instrumental analysis, one prosthodontist examined the same teeth using a spectrophotometer （ShadepilotTM, Degudent, Hanau-Wolfgang, Germany, software 2.40）. Overall, instrumental analysis is more accurate and reproducible than a visual assessment. however, the difference is clinically acceptable.

关键词： shade selection visual analysis instrumental analysis spectrophotometer

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医疗器械临床试验审批的监管考量

中国药物评价 2024年第2期41卷 85-87页

作者：程茂波彭亮郭晓磊鞠珊穆兰兰张旭国家药品监督管理局医疗器械技术审评中心北京100081

目的:对医疗器械临床试验审批监管法规的优化过程及技术审评要求关注点进行研究讨论。方法:通过梳理临床试验审批相关法规、规范性文件、临床试验审批目录、临床试验审评关注点,阐述了医疗器械临床试验审批技术审查基本原则和监管要求... 详细信息

目的:对医疗器械临床试验审批监管法规的优化过程及技术审评要求关注点进行研究讨论。方法:通过梳理临床试验审批相关法规、规范性文件、临床试验审批目录、临床试验审评关注点,阐述了医疗器械临床试验审批技术审查基本原则和监管要求。结果:随着医疗器械临床试验审批监管体系的不断完善,监管要求更加科学合理。结论:医疗器械临床试验审批监管法规更加优化,程序更加完善,技术审查要求更加科学合理,明确了临床试验审批技术审查基本原则,统一了审评尺度,促进了对人体高风险第三类医疗器械的可及性。

关键词：医疗器械临床试验临床试验审批技术审评监管

Differentiation of expression profi les of two calcineurin subunit genes in chicken skeletal muscles during early postnatal growth depending on anatomical location of muscles and breed

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Journal of Integrative Agriculture 2016年第5期15卷 1085-1094页

作者： shan Yan-ju XU Wen-juan SHU Jing-ting ZHANG Ming SONG Wei-tao TAO Zhi-yun ZHU Chun-hong LI Hui-fang Key Laboratory for Poultry Genetics and Breeding of Jiangsu Province Institute of Poultry Science Chinese Academy of Agricultural Science

Calcineurin（Cn or CaN） is implicated in the control of skeletal muscle fiber phenotype and hypertrophy. however, little information is available concerning the expression of Cn in chickens. In the present study, the expression of two Cn subunit genes（Cn Aα and Cn B1） was quantified by q PCR in the lateral gastrocnemius（LG, mainly composing of red fast-twitch myofibers）, the soleus（mainly composing of red slow-twitch myofibers） and the extensor digitorum longus（EDL, mainly composing of white fast-twitch myofibers） from Qingyuan partridge chickens（QY, slow-growing chicken breed） and Recessive White chickens（RW, fast-growing chicken breed） on different days（1, 8, 22, 36, 50 and 64 days post-hatching）. Although Cn Aα and Cn B1 gene expressions were variable with different trends in different skeletal muscles in the two chicken breeds during postnatal growth, it is highly muscle phenotype and breed specific. In general, the levels of Cn Aα and Cn B1 gene expressions of the soleus were lower than those of EDL and LG in both chicken breeds at the same stages. Compared between the two chicken breeds, the levels of Cn Aα gene expression of the three skeletal muscles in QY chickens were higher than those in RW chickens on days 1 and 22. however, on day 64, the levels of both Cn Aα and Cn B1 gene expressions of the three skeletal muscles were lower in QY chickens than those in RW chickens. Correlation analysis of the levels of Cn Aα and Cn B1 gene expressions of the same skeletal muscle showed that there were positive correlations for all three skeletal muscle tissues in two chicken breeds. These results provide some valuable clues to understand the role of Cn in the development of chicken skeletal muscles, with a function that may be related to meat quality.

关键词： calcineurin chicken skeletal muscle expression

武汉市医学类专业男大学生对睾丸自检的意识和实践现状调查

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国际生殖健康／计划生育杂志 2024年第4期43卷 289-292,304页

作者：黄妹妹罗瑞君何素芬曹凤菊乐珊许雪琼武汉大学人民医院肿瘤中心 430000

目的:调查武汉市医学类专业男大学生对睾丸自检(testicular self-examination,TSE)的认识和实践现状,并探讨TSE认识和实践之间的关联。方法:采用方便抽样法抽取武汉大学第一临床学院和第二临床学院、武昌理工学院健康与护理学院、武汉... 详细信息

目的:调查武汉市医学类专业男大学生对睾丸自检(testicular self-examination,TSE)的认识和实践现状,并探讨TSE认识和实践之间的关联。方法:采用方便抽样法抽取武汉大学第一临床学院和第二临床学院、武昌理工学院健康与护理学院、武汉城市学院医学部和湖北中医药大学2023年1—11月在校男医学生500例,通过汉化的TSE意识量表分析医学类专业男大学生的TSE意识、实践、知识现状和影响TSE实践的障碍和促进因素。结果:500名受访者的平均年龄为(21.93±1.72)岁,仅45.4%的学生听说过TSE。在TSE意识方面,受访者中31.3%认为全部男性应该了解TSE,57.7%认为TSE有助于睾丸癌的早期诊断,43.6%认为男性应该在21~25岁之间开始TSE,52.9%的学生不知道TSE的最佳频率。在TSE实践方面,只有37.4%的学生平时做过TSE,但只有22.5%定期练习,22.0%的学生知道TSE的流程和步骤。在TSE知识方面,有4个条目的正确率达50%以上,其余5个条目的正确率均小于50%。在影响TSE实践的障碍和促进因素方面,对于大多数受访者来说,阻碍TSE的障碍是害怕发现肿块、觉得TSE很尴尬,并觉得老年男性才应该进行该检查。结论:有必要在医学类专业学生的培训中强调TSE的重要性,使这些学生掌握TSE的健康知识和技能,并鼓励男生定期进行TSE,更好地促进其在公共健康教育中的社会效应。

关键词：院校,医学学生睾丸肿瘤组织和管理健康教育睾丸自检

Traumatic neuroma of remnant cystic duct mimicking duodenal subepithelial tumor:A case report

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World Journal of Clinical Cases 2020年第17期8卷 3821-3827页

作者： Dong-Hwan Kim Ji-ho Park Jin-Kyu Cho jung-Wook Yang Tae-Han Kim Sang-ho Jeong Young-Hye Kim Young-Joon Lee Soon-Chan hong Eun-jung jung Young-Tae ju Chi-Young Jeong ju-Yeon Kim Department of Surgery Gyeongsang National University College of MedicineGyeongsang National University HospitalJinju 52727South Korea Department of Pathology Gyeongsang National University College of MedicineGyeongsang National University HospitalJinju 52727South Korea

BACKGROUND Gastrointestinal subepithelial tumors(GSTs),incidentally detected during upper gastrointestinal(GI)endoscopy,may be lesions derived from the GI wall or may be caused by compression from external *** general,traumatic neuroma is a benign nerve tumor that results from postoperative nerve injury,occurring in the bile duct as one of the complications after *** is the first case report demonstrating that neuroma of the cystic duct can be incorrectly perceived as a duodenal subepithelial tumor by compressing the duodenal *** SUMMARY We report the case of a 72-year-old man with traumatic neuroma of the cystic duct after *** tumor was mistaken for a duodenal subepithelial tumor on preoperative upper GI endoscopy and endoscopic ultrasonography due to external compression of the GI *** patient had no symptoms,and his laboratory test results were ***,in a series of follow-up endoscopies,the tumor was found to have grown in size,so it was surgically *** lesion was completely removed by laparoscopic endoscopic cooperative *** patient was discharged on postoperative day 7 without *** Traumatic neuroma of the cystic duct can be mistaken for GSTs in GI endoscopy.

关键词： Case report Neuroma Tumor Endoscopy Laparoscopy Cholecystectomy

Extracts of Portulaca oleracea promote wound healing by enhancing angiology regeneration and inhibiting iron accumulation in mice

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Chinese Herbal Medicines 2022年第2期14卷 263-272页

作者： Jinglin Guo juan Peng Jing Han Ke Wang Ruijuan Si Hui shan Xiaoying Wang ju Zhang School of Nursing Qingdao UniversityQingdao 266071China Surgery of Traditional Chinese Medicine Second Affiliated Hospital of Tianjin University of Traditional Chinese MedicineTianjin 300150China School of Pharmacy Qingdao UniversityQingdao 266071China

Objective:To investigate the role of Portulaca oleracea(POL)in promoting revascularization and reepithelization as well as inhibiting iron aggregation and inflammation of deep tissue pressure injury(DTPI).Methods:The hydroalcoholic extract of POL(P)and aqueous phase fraction of POL(PD)were prepared based on maceration and liquid–liquid *** number of new blood vessels and VEGF-A expression level were assessed using H&E stain and Western blot on injured muscle to examine the role of POL different extracts in *** iron distribution and total elemental iron of injured muscle were detected using laser ablation inductively coupled plasma mass spectrometry(ICP-MS)and Perls’staining to determine whether POL extracts can inhibit the iron ***,the ability of POL extracts to promote wound healing by combining re-epithelization time,inflammation degree and collagen deposition area were comprehensively ***:In vitro,we observed a significant increase in HUVEC cell viability,migration rate and the number of the tube after P and PD treatment(Pjured tissue,evident from more new blood vessels,higher expression of VEGF-A and decreased muscle iron concentration of treatment groups compared with no-treatment groups(Phorter re-epithelization time,reduced inflammatory infiltration and distinct collagen deposition were associated with administration of P and PD(Pjured muscle after ischemia–reperfusion,highlighting the potential of POL in the DTPI treatment.

关键词： deep tissue pressure injur ischemia-reperfusion Portulaca oleracea L. tissue repair wound healing

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氢燃料电池用气浮离心空压机实验与模拟研究

风机技术 2024年第3期66卷 29-34页

作者：李栋王琪杨山举张丽君祝艺鸣朱学卫西北农林科技大学机械与电子工程学院

气浮轴承离心空压机具有无油、高效、低成本、轻量化和动态响应性好等优点,已成为车载氢燃料电池空压机的最佳选择。本文介绍了自主研发的额定压比2.8、质量流量130g/s、转速88000r/min、功率22kW的两级气浮轴承离心空压机,用于匹配电... 详细信息

气浮轴承离心空压机具有无油、高效、低成本、轻量化和动态响应性好等优点,已成为车载氢燃料电池空压机的最佳选择。本文介绍了自主研发的额定压比2.8、质量流量130g/s、转速88000r/min、功率22kW的两级气浮轴承离心空压机,用于匹配电堆功率130kW的车载氢燃料电池。在离心空压机气动性能试验台上测试了空压机在60000~95000r/min范围内的气动性能,同时构建了离心空压机的泄漏通流模型并对其进行了数值模拟,最后将模拟结果与实验数据进行了对比分析。研究结果表明,该离心空压机在实验时最大转速达95000r/min,最大绝热效率可达77.04%。

关键词：氢燃料电池离心空压机箔片动压气浮轴承实验研究泄漏通流模型可靠性

Clinical efficacy of combined topical 0.05%cyclosporine A and 0.1%sodium hyaluronate in the dry eyes with meibomian gland dysfunction

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International Journal of Ophthalmology(English edition) 2018年第4期11卷 593-600页

作者： ho-Yun Kim Ji-Eun Lee Ha-Na Oh ju-Whan Song Sang-Youp Han Jong-Soo Lee Department of Ophthalmology Maryknoll Medical CenterBusan 48972South Korea Department of Ophthalmology Pusan National University Yangsan HospitalYangsan 50612South Korea Department of Ophthalmology Inje University Baek HospitalBusan 47392South Korea Department of Ophthalmology Kosin University hospitalBusan 49267South Korea Sungrno Eye Clinic Busan 48064South Korea Department of Ophthalmology Pusan National University HospitalBusan 49241South Korea Medical Research Institute Pusan National University HospitalBusan 49241South Korea

AIM： To investigate the efficacy of combined topical 0.05% cyclosporine A（CsA; Restasis~？, Allergan pharmaceuticals, USA） and 0.1% sodium hyaluronate treatment in dry eyes with meibomian gland dysfunction（MGD）.METhoDS： In a retrospective analysis, 53 patients（106 eyes） with MGD were enrolled and performed lid warm massage for 10 min daily and be instilled preservative free sodium hyaluronate 0.1% eye drops 4 times daily. Patients were divided into subjects treated with topical 0.05% CsA and preservative free sodium hyaluronate vehicle（experimental group, n=74 eyes） and subjects treated with the preservative free sodium hyaluronate vehicle（control group, n=32 eyes）. They were evaluated at baseline and 1, 2, and 3 mo for subjective symptoms and objective signs including tear film break-up time（t BUT）, Schirmer test, corneal staining（CS） score, lid margin telangiectasia（LMT）, meibomian gland secretion（MGS）, and conjunctival injection（CI）.RESULTS： In the short-term treatment, the experimental group showed a statistically significant improvement in the ocular surface disease index（OSDI; P〈0.001）, tBUT（P=0.004）, Schirmer test score（P=0.008） and LMT（P=0.021） by repeated measure ANOVA. Additionally, mean changes from baseline in OSDI（P〈0.001）, tBUT（P=0.001）, Schirmer test score（P=0.029）, CS score（P=0.047）, LMT（P=0.002）, CI（P=0.030） were improved better in the experimental group than in the control group at 3 mo. however, there was no significant difference between the two groups in MGS（P=0.67）.CONCLUSION： In dry eyes with MGD, 0.05% CsA improves the tear film stability as well as subjective ocular discomfort, and is effective in controlling lid margin inflammation.

关键词： 0.05% cyclosporine 0.1% hyauronate meibomian gland dysfunction dry eye

Iron sulfides with dopamine-derived carbon coating as superior performance anodes for sodium-ion batteries

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Nano Research 2019年第10期12卷 2609-2613页

作者： Aihua Jin Seung-ho Yu Jae-Hyuk Park Seok Mun Kang Mi-ju Kim Tae-Yeol Jeon junyoung Mun Yung-Eun Sung Center for Nanoparticle Research Institute for Basic Science(IBS)Seoul 08826Republic of Korea School of Chemical and Biological Engineering Seoul National UniversitySeoul 08826Republic of Korea Department of Chemical and Biological Engineering Korea University145 Anatn-roSeongbtik-guSeoul 02841Republic cf Korea Beamline Department Pohang Accelerator Laboratory(PAL)Pohang 37673Republic of Korea Department of Energy and Chemical Engineering Incheon National University12-1Songdo-dong Yeonsu-guIncheon 22012Republic of Korea

High energy ball-milled iron sulfides with thin carb on layer coati ng(BM-FeS/C composites)were prepared by the simple and econo mical ***-milled process,followed by carb on coati ng,reduced the particle size and increased the electrical con *** n employed as sodium-ion battery ano des,BM?F eS/C composites showed extremely high electrochemical performa nee with reversible specific capacity of 589.8 mAh·g^-1 after 100 cycles at a current density of 100 mA·g^-*** also exhibited superior rate capabilities of 375.9 mAh·g^-1 even at 3.2 Ag^1 and 423.6 mAh·g^-1 at 1.5 Ag_1.X-ray absorptio n near edge structure an alysis con firmed the electrochemical pathway for con version reaction of BM-FeS/C composites.

关键词： sodium-ion batteries iron sulfides high energy ball-milling dopamine X-ray absorption near edge structure