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Ultra-wideband Low-Detectable Coding Metasurface

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Chinese Journal of Electronics 2019年第6期28卷 1265-1270页

作者： LIU Guanghong LIU Jiayi zhao shan SU Jianxun Information Science Academy of China Electronic Technology Group Corporation College of Information Engineering Communication University of China School of New Media Beijing Institute of Graphic Communication

A coding metasurface is designed based on hybrid Array pattern synthesis(APS) and Particle swarm optimization(PSO) method for ultra-wideband low-detectable application. The metasurface is composed of Electromagnetic band-gap(EBG) structures of two Minkowski fractal elements with reflection phase difference of 180°(±37°) over a wide frequency range. Two different types of EBG unit cell printed on a thin grounded dielectric substrate produce reflection phase difference of about 180 degrees over a wide frequency range. Ultra-wideband Radar cross section(RCS) reduction results from the phase cancellation between two local waves produced by these two unit cells. The diffuse scattering of EM waves is caused by the optimization of phase distribution, leading to a low monostatic and bistatic RCS *** proposed metasurface can achieve 10 dB monostatic and bistatic RCS reduction in a wide frequency band from 5.8 to 18.0 GHz with a ratio bandwidth(fH/fL) of 3.10:1 under normal incidence for both polarizations. The theoretical analysis, simulation and experiment results are in good agreement and validate the proposed metasurface can achieve ultra-wideband RCS reduction and diffuse scattering.

关键词： Metasurface Ultra-wideband Low-detectable Phase cancellation

Expression of c-erbB-2 and glutathione S-transferase-pi in hepatocellular carcinoma and its adjacent tissue

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World Journal of Gastroenterology 2005年第28期11卷 4404-4408页

作者： zhao-shan Niu Mei Wang Department of Pathology Medical College of Qingdao University Qingdao 266021 Shandong ProvinceChina Institute of Education the University of Reading Britain RG6 IHY Reading United Kingdom

AIM： To investigate the possible role of c-erbB-2 and glutathione S-transferase （GST-Pi） in primary hepatocellular carcinogenesis and the relationship between liver hyperplastic nodule （LHN）, liver cirrhosis （LC）, and hepatocellular carcinoma （HCC）.METHODS： The expression of c-erbB-2 and GST-Pi was detected immunohistochemically in 42 tissue specimens of HCC and 77 specimens of its adjacent tissue.RESULTS： The positive expression of c-erbB-2 in LHN （28.6%） was significantly higher than that in LC （0%）（P = 0.032〈0.05）, but no significant difference was seen between HCC and LHN or LC （P〉0.05, X^2 = 0.002, 3.447）.The positive expression of GST-Pi in HCC （89.6%） or LHN （72.2%） was significantly higher than that in LC（22.9%, P〈0.001, ;X^2= 49.91, 16.96）. There was a significant difference between HCC and LHN （P〈0.05,X^2= 6.353）.CONCLUSION： The c-erbB-2 expression is an early event in the pathogenesis of HCC. GST-Pi may be a marker enzyme for immunohistochemical detection of human HCC and its preneoplastic lesions. LHN seems to be a preneoplastic lesion related to hepatocarcinogenesis.

关键词： Liver neoplasm Hyperplastic nodule C-erbB-2 gene GST-pi gene Immunohistochemistry

TD-DFT Studies on Electronic and Spectral Properties of Platinum（II） Complexes with Phenol and Pyridine Groups

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Chemical Research in Chinese Universities 2013年第2期29卷 361-365页

作者： zhao shan-shan SHI Li-li SU Zhong-min GENG Yun zhao Liang Institute of Functional Material Chemistry Faculty of Chemistry Northeast Normal University Changchun 130024 P. R. China

The molecular structures of the ground and the lowest triplet states for a series of Pt（ll） complexes PtLCl（l）[L=6-（2-hydroxyphenyl）-2,2＇-bipyridine], Pt（pp）2[pp=2-（2-hydroxyphenyl）pyridine]（2）, PtbpyClz（bpy=2,2＇- bipyridine）（3）, and the free tridentate L ligand（4） were optimized by the density functional theory B3LYP and UB3LYP methods, respectively. On the basis of optimized geometries, the spectral properties were investigated with time-dependent density functional theory（TD-DFT）. In comparison with those of complexes 2 and 3, the more rigid structure of complex 1 together with its low rate of the radiationless decay via nonemissive d-d state leads to higher photoluminescence quantum efficiency. And the phosphorescence quantum efficiency of complex 1 can be easily controlled by modifying auxiliary ligands. The introduction of fluorine ligand into complexes can effectively increase the radiation transition rate and decrease the radiationless d-d transition rate, and as a result, a novel complex PtLF（5） might be a good phosphorescent material suitable for organic electronic devices.

关键词： Pt(II) complex Time-dependent density functional theory(TD-DFT) Optoelectronic property

Driving mechanisms of nitrogen transport and transformation in lacustrine wetlands

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Science China Earth Sciences 2016年第3期59卷 464-476页

作者： zhao shan ZHOU Nian Qing SHEN Xin Ping Department of Hydraulic Engineering Tongji UniversityKey Laboratory of Yangtze River Water Environment Ministry of Education Shanghai 200092 China School of Civil and Environmental Engineering Georgia Institute of Technology Atlanta Georgia 30332 USA Dongting Lake Water Resources Administration Bureau of Hunan Province Changsha 410007 China

As an essential component of proteins and genetic material for all organisms, nitrogen(N) is one of the major limiting factors that control the dynamics, biodiversity and functioning of lacustrine wetlands, in which intensified N biogeochemical activities take place. Reactive N loaded into wetland ecosystems has been doubled due to various human activities, including industrial, agricultural activities and urbanization. The main driving mechanisms of N transport and transformation in lacustrine wetlands are categorized to pushing forces and pulling forces in this study. Geomorphology, wetland age, N concentrations, and temperature are the main pushing forces(passive forces); whereas water table variation, oxygen concentration, other elements availability, oxidation-reduction potential(Eh) and p H, and microorganisms are the predominant pulling forces(active forces). The direction and kinetic energy of reactions are determined by pulling forces and then are stimulated by pushing forces. These two types of forces are analyzed and discussed separately. Based on the analysis of driving mechanisms, possible solutions to wetland N pollutions are proposed at individual, regional and global scales, respectively. Additional research needs are addressed to obtain a thorough understanding of N transport and transformations in wetlands and to reduce detrimental impacts of excessive N on such fragile ecosystems.

关键词： Nitrogen Driving mechanisms Transport and transformation Excessive loading Lacustrine wetlands

Cataract surgery in aged patients:phacoemul-sification or small-incision extracapsular cataract surgery

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International Journal of Ophthalmology(English edition) 2011年第5期4卷 513-518页

作者： Tao Jiang, shan-Yao zhao Department of Ophthalmology the Affiliated Hospital of Medical College Qingdao University Qingdao 266003 Shandong Province China The Infectious Diseases Department Eastern Branch of the Affiliated Hospital of Medical College Qingdao University Qingdao 266100 Shandong Province China

AIM: To evaluate the effects and safety of phacoemulsification (Phaco) or small-incision extracapsular cataract surgery (SICS) and intraocular lens (IOL) implantation for aged patients. METHODS: Totally 137 aged patients (149 eyes) underwent cataract operation in the case of stable systemic condition, the blood pressure less than 160/95mmHg, blood glucose less than 8mmol/L, and under the help of electrocardiogram surveillance by anesthesiologists during the operation. 106 aged patients (114 eyes) underwent Phaco while 31 aged patients (35 eyes) underwent SICS. The postoperative visual acuity, corneal endothelial cell loss, surgery time and major complications were observed and analyzed retrospectively. RESULTS: The best-corrected visual acuity (BCVA) of >= 0.6 was achieved in 135 eyes (92.6%) at 1 month postoperatively (chi(2)=259.730, P 0.05). Postoperative corneal endothelial cell loss was 18.6%, in PHACO group, the rate was 18.5%; in SICS group, the rate was 19.0%, the difference of which was no significant (chi(2)=0.102, P>0.05). The surgery time was different in two groups. No severe complications occurred. CONCLUSION: Both Phaco and SICS combined with IOL implantation for aged patients are effective and safe. Before surgery, detailed physical examination should be performed. When the systemic condition is stable, cataract surgery for aged patients is safe.

关键词： phacoemulsification small-incision extracapsular cataract surgery intraocular lens aged cataract diabetes hypertension

Circular RNAs in hepatocellular carcinoma:Recent advances

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World Journal of Gastrointestinal Oncology 2022年第6期14卷 1067-1085页

作者： zhao-shan Niu Wen-Hong Wang Laboratory of Micromorphology School of Basic MedicineQingdao UniversityQingdao 266071Shandong ProvinceChina Department of Pathology School of Basic MedicineQingdao UniversityQingdao 266071Shandong ProvinceChina

Circular RNAs(circRNAs)have covalently closed loop structures at both ends,exhibiting characteristics dissimilar to those of linear *** evidence suggests that aberrantly expressed circRNAs play crucial roles in hepatocellular carcinoma(HCC)by affecting the proliferation,apoptosis and invasive capacity of HCC *** circRNAs may be used as biomarkers to diagnose and predict the prognosis of ***,circRNAs are expected to become novel biomarkers and therapeutic targets for ***,we briefly review the characteristics and biological functions of circRNAs,focusing on their roles in HCC to provide new insights for the early diagnosis and targeted therapy of HCC.

关键词： Hepatocellular carcinoma Circular RNAs Function Diagnosis Biomarkers Targeted therapy

Theoretical characterization of hole mobility in BTBPD

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Chinese Chemical Letters 2013年第10期24卷 945-948页

作者： Tie-Chao Jiang Zhong-Yu Wang Bei-Bei Du shan-shan zhao China-Japan Union Hospital of Jilin University Jilin University State Key Laboratory of Supramolecular Structure and Materials Jilin University

（ E）-5,5＇-Bis（ 5-（ benzo[ b ]thiophen- 2-yl ）thiophen-2-yl ）-1,1＇-bis（ 2-ethylhexyl ）-[ 3,3＇-bipyrrolylidene ]- 2,2＇（1H, l＇H）-dione （BTBPD） has been reported by Zhang and co-workers. To further understand the charge-transporting nature of BTBPD, the density-functional theory （DFF） and the Marcus charge transfer theory were performed. The character of the frontier molecular orbitals, reorganization energies and transfer integrals in different directions were considered in details. The results revealed that the BTBPD has high hole transport efficiency （μ = 0.29 cm2 V-1 s-1 ）. The intermolecular π-π interaction and S...S interaction provide the holes transport channels.

关键词： BTBPD DFT Marcus charge transport theory

Hepatic macrophages in drug-induced liver injury

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Liver Research 2019年第3期3卷 170-175页

作者： zhao shan Cynthia Ju Center for Life Sciences School of Life SciencesYunnan UniversityKunmingChina Department of Anesthesiology UTHealth McGovern Medical SchoolHoustonTXUSA

Drug-induced liver injury(DILI)is a major public health *** DILI,for example,acetaminophen overdose accounts for half of acute liver failure in the United ***,the most problematic type of DILI affecting drug development and health care is idiosyncratic DILI,which occurs unpredictably in a small population of patients taking the drug and the latency could be several weeks to *** knowledge on the pathogenesis of DILI suggest that hepatic macrophages play a central role in the initiation,progression and restoration stages of DILI,which make hepatic macrophages attractive as therapeutic *** macrophages consist of liver resident macrophages(also known as Kupffer cells,KCs)and infiltrating monocyte-derived macrophages(MoMF).There is a growing appreciation that hepatic macrophage is very plastic,and assumes diverse phenotypes and functions in response to micro-environmental *** this review,we will summarize studies on the role of hepatic macrophages in both intrinsic DILI and idiosyncratic DILI,followed by discussing the prognostic and therapeutic potentials of targeting hepatic macrophages and the obstacles in studying hepatic macrophages.

关键词： Hepatic macrophages Acetaminophen(APAP) Drug Liver injury Intrinsic drug-induced liver injury(DILI) Idiosyncratic DILI

Decadal Variations of Extreme Tropical Cyclones Influencing China during 1949-2009

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Advances in Climate Change Research 2012年第3期3卷 121-127页

作者： zhao shan-shan WANG Xiao-Ling National Climate Center China Meteorological AdministrationBeijing 100081China

Decadal variations of extreme tropical cyclones （TCs） influencing China were. investigated based on the tracks, landfall information, precipitation and wind data during 1949-2009. The extreme landfall date events are less in the 1970s and 2000s. The number of extreme events of maximum wind speed and minimum pressure near TC＇s center reached the highest in the 2000s. The extreme rain duration events had the highest frequence in the 1970s, and the extreme strong wind duration events had the maximum frequence in the 1980s. The number of stations whereat the extreme maximum daily precipitation or process precipitation is observed, is the largest in the 1960s, and the number of stations whereat daily maximum wind speed events axe observed, is the largest in the 1980s.

关键词： tropical cyclone extreme events decadal variation maximum landfall intensity landfall date maximum precipitation