检索结果-南通市图书馆

Configuring single-layer MXene nanosheet onto natural wood fiber via C–Ti–C covalent bonds for high-stability Li-S batteries

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2024年第8期95卷 701-711页

作者： Yangyang Chen Yu Liao Ying Wu Lei Li Zhen Zhang sha luo Yiqiang Wu Yan Qing College of Materials Science and Technology Central South University of Forestry and Technology

Lithium-sulfur batteries（LSBs） are considered promising candidates for next-generation battery technologies owing to their outstanding theoretical energy density and cost-effectiveness. However, the low conductivity and polysulfide shuttling effect of S cathodes severely hamper the practical performance of LSBs. Herein, in situ-generated single layer MXene nanosheet/hierarchical porous carbonized wood fiber（MX/PCWF） composites are prepared via a nonhazardous eutectic activation strategy coupled with pyrolysis-induced gas diffusion. The unique architecture, wherein single layer MXene nanosheets are constructed on carbonized wood fiber walls, ensures rapid polysulfide conversion and continuous electron transfer for redox reactions. The C–Ti–C bonds formed between MXene and PCWF can considerably expedite the conversion of polysulfides, effectively suppressing the shuttle effect. An impressive capacity of 1301.1 m A h g-1at 0.5 C accompanied by remarkable stability is attained with the MX/PCWF host, as evidenced by the capacity maintenance of 722.6 m A h g-1after 500 cycles. Notably, the MX/PCWF/S cathode can still deliver a high capacity of 886.8 m A h g-1at a high S loading of 5.6 mg cm-2.The construction of two-dimensional MXenes on natural wood fiber walls offers a competitive edge over S-based cathode materials and demonstrates a novel strategy for developing high-performance batteries.

关键词： C–Ti–C bonds Lithium-sulfur batteries MXene nanosheets S cathodes Wood fiber

Semantic Consistency and Correctness Verification of Digital Traffic Rules

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Engineering 2024年第2期33卷 47-62页

作者： Lei Wan Changjun Wang Daxin luo Hang Liu sha Ma Weichao Hu Policy Standardand Patent DepartmentIntelligent Automotive Solution BUHuawei Technologies Co.Ltd.Beijing 100094China Research Institute for Road Safety of the Ministry of Public Security Beijing 100062China

The consensus of the automotive industry and traffic management authorities is that autonomous vehicles must follow the same traffic laws as human drivers.Using formal or digital methods,natural language traffic rules can be translated into machine language and used by autonomous vehicles.In this paper,a translation flow is designed.Beyond the translation,a deeper examination is required,because the semantics of natural languages are rich and complex,and frequently contain hidden assumptions.The issue of how to ensure that digital rules are accurate and consistent with the original intent of the traffic rules they represent is both significant and unresolved.In response,we propose a method of formal verification that combines equivalence verification with model checking.Reasonable and reassuring digital traffic rules can be obtained by utilizing the proposed traffic rule digitization flow and verification method.In addition,we offer a number of simulation applications that employ digital traffic rules to assess vehicle violations.The experimental findings indicate that our digital rules utilizing metric temporal logic(MTL)can be easily incorporated into simulation platforms and autonomous driving systems(ADS).

关键词： Autonomous driving Traffic rules Digitization Formalization Verification

Simulation and fabrication of in vitro microfluidic microelectrode array chip for patterned culture and electrophysiological detection of neurons

在线全文

学校读者我要写书评

暂无评论

Nanotechnology and Precision Engineering 2024年第2期7卷 1-10页

作者： Yan Yang Shihong Xu Yu Deng Yaoyao Liu Kui Zhang Shiya Lv Longze sha Qi Xu Xinxia Cai Jinping luo State Key Laboratory of Transducer Technology Aerospace Information Research InstituteChinese Academy of SciencesBeijing 100190China School of Electronic Electrical and Communication EngineeringUniversity of Chinese Academy of SciencesBeijing 100049China State Key Laboratory of Medical Molecular Biology Institute of Basic Medical SciencesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100005China

To enable the detection and modulation of modularized neural networks in vitro,this study proposes a microfluidic microelectrode array chip for the cultivation,compartmentalization,and control of neural cells.The chip was designed based on the specific structure of neurons and the requirements for detection and modulation.Finite-element analysis of the chip’s flow field was conducted using the COMSOL Multiphysics software,and the simulation results show that the liquid within the chip can flow smoothly,ensuring stable flow fields that facilitate the uniform growth of neurons within the microfluidic channels.By employing MEMS technology in combination with nanomaterial modification techniques,the microfluidic microelectrode array chip was fabricated successfully.Primary hippocampal neurons were cultured on the chip,forming a well-defined neural network.Spontaneous electrical activity of the detected neurons was recorded,exhibiting a 23.7%increase in amplitude compared to neuronal discharges detected on an open-field microelectrode array.This study provides a platform for the precise detection and modulation of patterned neuronal growth in vitro,potentially serving as a novel tool in neuroscience research.

关键词： Microﬂuidic Microelectrode array In vitro Neural chip

Creep property and microstructural evolution of DD11 alloy under high temperature and low stress

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rare Metals 2024年第2期43卷 810-816页

作者： Yan-Fei Liu Jiang-Bo sha Yun-Song Zhao Chen-Guang Liu Yuan-Yuan Guo Jian Zhang Yu-Shi luo School of Materials Science and Engineering Beihang UniversityBeijing100191China Science and Technology on Advanced High Temperature Structural Materials Laboratory Beijing Institute of Aeronautical MaterialsBeijing100095China

In this paper,the interrupted and ruptured creep tests were carried out in a novel second generation single crystal superalloy named DD11 at 1100℃/130 MPa.The alloy exhibited typical creep curve including primary,steady,and tertiary three creep stages.The microstructural evolution at different stages of the creep were analyzed by scanning electron microscopy(SEM)and transmission electron microscopy(TEM).The results show that theγ′phases transform into rafted structure at the early stage of the steady creep and keep stable during the steady creep stage.As the creep goes on,the rafted structure further coarsens and the topological inversion occurs.In addition,at the primary creep,the dislocations mainly move in theγmatrix and pile up in theγ/γ′interface since the matrix channels widen slightly.The formation of the regular interfacial dislocation networks occurs at the early stage of the steady creep.Under the low stress,the dominated deformation mechanism during steady creep stage is the climbing of the〈010〉type edge dislocation.Furthermore,the effect of the deformation mechanism on creep property was discussed in detail.

关键词： DD11 alloy Creep property Interrupted creep test Rafted structure Deformation mechanism

Detection and analysis of landslide geomorphology based on UAV vertical photogrammetry

在线全文

学校读者我要写书评

暂无评论

Journal of Mountain Science 2024年第4期21卷 1190-1214页

作者： BI Rui GAN Shu YUAN Xiping LI Kun LI Raobo luo Weidong CHEN Cheng GAO sha HU Lin ZHU Zhifu School of Land and Resources Engineering Kunming University of Science and TechnologyKunming 650093China Plication Engineering Research Center of Spatial Information Surveying and Mapping Technology in Plateau and Mountainous Areas Set by Universities in Yunnan Province Kunming 650093China West Yunnan University of Applied Sciences Key Laboratory of Mountain Real Scene Point Cloud Data Processing and Application for Universities in Yunnan ProvinceDali 671006China

High-resolution landslide images are required for detailed geomorphological analysis in complex topographic environment with steep and vertical landslide distribution.This study proposed a vertical route planning method for unmanned aerial vehicles(UAVs),which could achieve rapid image collection based on strictly calculated route parameters.The effectiveness of this method was verified using a DJI Mavic 2 Pro,obtaining high-resolution landslide images within the Dongchuan debris flow gully,in the Xiaojiang River Basin,Dongchuan District,Yunnan,China.A three-dimensional(3D)model was constructed by the structure-from-motion and multi-view stereo(SfM-MVS).Micro-geomorphic features were analyzed through visual interpretation,geographic information system(GIS),spatial analysis,and mathematical statistics methods.The results demonstrated that the proposed method could obtain comprehensive vertical information on landslides while improving measurement accuracy.The 3D model was constructed using the vertically oriented flight route to achieve centimeter-level accuracy(horizontal accuracy better than 6 cm,elevation accuracy better than 3 cm,and relative accuracy better than 3.5 cm).The UAV technology could further help understand the micro internal spatial and structural characteristics of landslides,facilitating intuitive acquisition of surface details.The slope of landslide clusters ranged from 36°to 72°,with the majority of the slope facing east and southeast.Upper elevation levels were relatively consistent while middle to lower elevation levels gradually decreased from left to right with significant variations in lower elevation levels.During the rainy season,surface runoff was abundant,and steep topography exacerbated changes in surface features.This route method is suitable for unmanned aerial vehicle(UAV)landslide surveys in complex mountainous environments.The geomorphological analysis methods used will provide references for identifying and describing topographic features.

关键词： UAV Landslide Vertical route SfM-MVS Topographic features

Distributed Graph Database Load Balancing Method Based on Deep Reinforcement Learning

在线全文

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2024年第6期79卷 5105-5124页

作者： Shuming sha Naiwang Guo Wang luo Yong Zhang Nanjing NARI Information&Communication Technology Co. Ltd.Nanjing210032China State Grid Electric Power Research Institute Nanjing211106China State Grid shanghai Municipal Eleciric Power Company Shanghai200122China

This paper focuses on the scheduling problem of workflow tasks that exhibit interdependencies.Unlike indepen-dent batch tasks,workflows typically consist of multiple subtasks with intrinsic correlations and dependencies.It necessitates the distribution of various computational tasks to appropriate computing node resources in accor-dance with task dependencies to ensure the smooth completion of the entire workflow.Workflow scheduling must consider an array of factors,including task dependencies,availability of computational resources,and the schedulability of tasks.Therefore,this paper delves into the distributed graph database workflow task scheduling problem and proposes a workflow scheduling methodology based on deep reinforcement learning(DRL).The method optimizes the maximum completion time(makespan)and response time of workflow tasks,aiming to enhance the responsiveness of workflow tasks while ensuring the minimization of the makespan.The experimental results indicate that the Q-learning Deep Reinforcement Learning(Q-DRL)algorithm markedly diminishes the makespan and refines the average response time within distributed graph database environments.In quantifying makespan,Q-DRL achieves mean reductions of 12.4%and 11.9%over established First-fit and Random scheduling strategies,respectively.Additionally,Q-DRL surpasses the performance of both DRL-Cloud and Improved Deep Q-learning Network(IDQN)algorithms,with improvements standing at 4.4%and 2.6%,respectively.With reference to average response time,the Q-DRL approach exhibits a significantly enhanced performance in the scheduling of workflow tasks,decreasing the average by 2.27%and 4.71%when compared to IDQN and DRL-Cloud,respectively.The Q-DRL algorithm also demonstrates a notable increase in the efficiency of system resource utilization,reducing the average idle rate by 5.02%and 9.30%in comparison to IDQN and DRL-Cloud,respectively.These findings support the assertion that Q-DRL not only upholds a lower average idle rate but also effectively curtails the ave

关键词： Reinforcement learning workflow task scheduling load balancing

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

复合材料涡轮轴结构损伤演化及失效机理

航空动力学报 2024年第5期39卷 138-153页

作者：沙云东黄靖轩骆丽白旭沈阳航空航天大学航空发动机学院辽宁省航空推进系统先进测试技术重点实验室沈阳110136

针对连续纤维增强复合材料涡轮轴结构损伤演化及失效机理分析,基于宏-细观力学跨尺度分析方法,建立了与轴结构试验件尺寸相符合的有限元仿真计算模型及细观力学代表体积元(RVE)模型,预测轴结构的损伤演化并分析其失效机理。反向扭矩下,[... 详细信息

针对连续纤维增强复合材料涡轮轴结构损伤演化及失效机理分析,基于宏-细观力学跨尺度分析方法,建立了与轴结构试验件尺寸相符合的有限元仿真计算模型及细观力学代表体积元(RVE)模型,预测轴结构的损伤演化并分析其失效机理。反向扭矩下,[45]_(6)轴结构的损伤始于界面开裂,裂纹向两侧钛合金扩展,钛合金的剪切变形最终带动纤维的断裂;正向扭矩下,[45]_(10)轴结构的损伤始于基体损伤,断口两侧钛合金相互挤压摩擦,最终将纤维剪断。开展复合材料失效模式验证试验,通过声发射及扫描电镜技术,实现对失效过程中不同失效模式的判别。将仿真结果与试验结果进行对比验证,验证了模型和方法的有效性。模拟涡轮轴结构在扭转载荷下的损伤演化过程及失效机理,预测失效强度。结果表明:0°和90°铺层时扭转强度最低,45°铺层时扭转强度最高,提高近3倍。本文研究提出的预测模型及分析结论为纤维增强复合材料的设计和应用提供依据。

关键词：复合材料涡轮轴损伤演化失效机理失效强度铺层角度

Gene replacement therapy in Bietti crystalline corneoretinal dystrophy:an open-label,single-arm,exploratory trial

在线全文

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2024年第5期9卷 2275-2284页

作者： Jinyuan Wang Jinlu Zhang Shicheng Yu Hongyan Li shaohong Chen Jingting luo Haibo Wang Yuxia Guan Haihan Zhang Shiyi Yin Huili Wang Heping Li Junle Liu Jingyuan Zhu Qiong Yang Ying sha Chuan Zhang Yuhang Yang Xuan Yang Xifang Zhang Xiuli Zhao Likun Wang Liping Yang Wenbin Wei Beijing Tongren Eye Center Beijing Key Laboratory of Intraocular Tumor Diagnosis and TreatmentBeijing Ophthalmology&Visual Sciences Key LabMedical Artificial Intelligence Research and Verification Key Laboratory of the Ministry of Industry and Information TechnologyBeijing Tongren HospitalCapital Medical University100730 BeijingChina School of Clinical Medicine Tsinghua University100084 BeijingChina Chigenovo Co. Ltd.102206 BeijingChina Department of Ophthalmology Peking University Third HospitalBeijing Key Laboratory of Restoration of Damaged Ocular NervePeking University Third Hospital100191 BeijingChina Department of Ophthalmology The Third People’s Hospital of Dalian116091 DalianChina Department of Biomedical Informatics School of Basic Medical SciencesPeking University Health Science Center100191 BeijingChina Institute of Systems Biomedicine Department of PathologySchool of Basic Medical SciencesPeking University Health Science Center100191 BeijingChina

Bietti crystalline corneoretinal dystrophy is an inherited retinal disease caused by mutations in CYP4V2,which results in blindness in the working-age population,and there is currently no available treatment.Here,we report the results of the first-in-human clinical trial(NCT04722107)of gene therapy for Bietti crystalline corneoretinal dystrophy,including 12 participants who were followed up for 180-365 days.This open-label,single-arm exploratory trial aimed to assess the safety and efficacy of a recombinant adeno-associated-virus-serotype-2/8 vector encoding the human CYP4V2 protein(rAAV2/8-hCYP4V2).Participants received a single unilateral subretinal injection of 7.5×10^(10)vector genomes of rAAV2/8-hCYP4V2.Overall,73 treatment-emergent adverse events were reported,with the majority(98.6%)being of mild or moderate intensity and considered to be procedure-or corticosteroid-related;no treatment-related serious adverse events or local/systemic immune toxicities were observed.Compared with that measured at baseline,77.8%of the treated eyes showed improvement in best-corrected visual acuity(BCVA)on day 180,with a mean±standard deviation increase of 9.0±10.8 letters in the 9 eyes analyzed(p=0.021).By day 365,80%of the treated eyes showed an increase in BCVA,with a mean increase of 11.0±10.6 letters in the 5 eyes assessed(p=0.125).Importantly,the patients’improvement observed using multifocal electroretinogram,microperimetry,and Visual Function Questionnaire-25 further supported the beneficial effects of the treatment.We conclude that the favorable safety profile and visual improvements identified in this trial encourage the continued development of rAAV2/8-hCYP4V2(named ZVS101e).

关键词： cor dystrophy crystalline

环状RNA hsa_circUCK2参与调控二氧化硅致肺纤维化进程

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

环境与职业医学 2024年第4期41卷 362-366,374页

作者：张聪罗薇王莎巢杰东南大学公共卫生学院环境医学工程教育部重点实验室江苏南京210009 东南大学医学院医学生理系江苏南京210009

[背景]肺纤维化疾病目前早期缺少筛查诊断方法,后期缺乏特效治疗措施,因此急需探究其机制并开发针对性的治疗方法。[目的]筛选病理条件下差异表达的环状RNA(circRNA)hsa_circUCK2的表达情况,探究其对肺纤维化的影响。[方法]在细胞实验中... 详细信息

[背景]肺纤维化疾病目前早期缺少筛查诊断方法,后期缺乏特效治疗措施,因此急需探究其机制并开发针对性的治疗方法。[目的]筛选病理条件下差异表达的环状RNA(circRNA)hsa_circUCK2的表达情况,探究其对肺纤维化的影响。[方法]在细胞实验中,使用小干扰RNA(siRNA)敲除HPF-a细胞中hsa_circUCK2,TGF-β1刺激HPF-a细胞,设立si-NC组、si-circUCK2组、si-NC+TGF-β1处理组、si-circUCK2+TGF-β1处理组4组,Western blot法检测4组HPF-a细胞中纤连蛋白(FN1)表达情况,划痕实验检测HPF-a细胞迁移能力,CCK-8实验检测TGF-β1刺激的2组(si-NC+TGF-β1处理组和si-circUCK2+TGF-β1处理组)HPF-a细胞活性。在动物实验中,健康SPF级雄性C57BL/6小鼠48只,随机分为生理盐水+si-con组,生理盐水+si-circ_0000115组,SiO_(2)+si-con组,SiO2+si-circ_0000115组4组。mmu_circ_0000115是hsa_circUCK2的小鼠同源基因,气管滴注siRNA敲除小鼠肺circRNA mmu_circ_0000115,48 h后通过气管滴注SiO2悬液(0.2 g·kg^(-1),50 mg·mL^(-1))构建小鼠肺纤维化模型,实时荧光定量PCR检测小鼠各脏器中敲除效率,Western blot检测肺组织中I型胶原α2蛋白(COL1A2)表达情况,天狼星红检测肺组织中胶原合成情况。[结果]在细胞实验中,Western blot结果显示,敲除hsa_circUCK2可下调TGF-β1刺激的HPFa细胞中FN1的表达水平(P <0.05);CCK-8实验和细胞划痕实验结果显示,hsa_circUCK2基因的下调可以抑制HPF-a细胞的增殖和迁移(P <0.01)。在动物实验中,实时荧光定量PCR结果显示,在各脏器中只有肺组织中被显著敲除mmu_circ_0000115(P <0.000 1);Western blot结果表明,与SiO2+si-con组相比,敲低mmu_circ_0000115可以降低COL1A2蛋白表达水平(P <0.000 1);天狼星红结果显示,敲低mmu_circ_0000115后,模型组小鼠肺组织中胶原的产生和沉积减少。[结论]敲低hsa_circUCK2抑制成纤维细胞活化和减少肺纤维化模型小鼠中胶原沉积。提示hsa_circUCK2参与肺纤维化进程,可能是肺纤维化的潜在治疗靶点。

关键词：环状RNA 转录组芯片 hsa_circUCK2 肺纤维化人肺成纤维-成人细胞