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Microbiological assessment of indoor air of a teaching hospital in Nigeria

Asian Pacific Journal of Tropical Biomedicine 2012年第6期2卷 465-468页

作者： Awosika sa Olajubu fa Amusa NA Department of Microbiology Olabisi Onabanjo University Department of Medical Microbiology & Parasitology Olabisi Onabanjo University Teaching Hospital Department of Plant Science & Applied Zoology Olabisi Onabanjo University

Objective:To investigate the quality of indoor air of different wards and units of Olabisi Onabanjo University Teaching Hospital, sagamu, to ascertain their contribution to infection rate in the ***:The microbial quality of indoor air of nine wards/units of Olabisi Onabanjo University Teaching Hospital, sagamu, Nigeria was conducted. Sedimentation technique using open Petri-dishes containing different culture media was employed and samplings were done twice daily, one in the morning shortly after cleaning and before influx of people/patients into the wards/units and the other in the evening when a lot of activities would have taken place in these wards. Isolates were identified according to standard ***:Results showed that there was a statistically significant difference(氈2= 6.0167) in the bacteria population of the different sampling time whereas it was not so for fungi population(氈2= 0.2857). Male medical ward(MMW) and male surgical general(MSG) recorded the highest bacterial and fungal growth while the operating theatre(OT) was almost free of microbial burden. The bacteria isolates were Staphylococcus aureus, Klebsiellasp., Bacillus cereus, Bacillus subtilis, Streptococcus pyogenes andSerratia marscenceswhile the fungi isolates includedAspergillus flavus, Penicilliumsp.,Fusariumsp.,Candida *** aureuswas the predominantly isolated bacterium whilePenicilliumsp. was the most isolated ***:Though most of the microbial isolates were potential and or opportunistic pathogens, there was no correlation between the isolates in this study and the surveillance report of nosocomial infection during the period of study, hence the contribution of the indoor air cannot be established. From the reduction noticed in the morning samples, stringent measures such as proper disinfection and regular cleaning, restriction of patient relatives' movement in and out of the wards/units need to be enforced so as to imp

关键词： Indoor air OOUTH Open-plate technique Nosocomial infections Staphylococcus aureus Microbiological assessment Microbial quality Bacterial isolate Fungal isolate Opportunistic pathogen Nosocomial infection Infection rate Microbial isolate Penicilliumsp Sedimentation technique

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首发儿童少年精神分裂症患者脑白质完整性与认知功能关系弥散张量成像研究

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中华行为医学与脑科学杂志 2024年第7期33卷 597-602页

作者：邵荣荣梁颖慧夏艳红肖洒李亚迪郭素芹新乡医学院第二附属医院精神十科新乡453002 新乡医学院第二附属医院心身医学一科新乡453002 新乡医学院第二附属医院儿童少年精神科新乡453002

目的采用弥散张量成像(diffusion tensor imaging,DTI)探讨首发儿童少年精神分裂症患者脑白质完整性与认知功能的关系。方法选择于2017年9月至2021年6月在新乡医学院第二附属医院儿童少年精神科住院的84例首发儿童少年精神分裂症患者作... 详细信息

目的采用弥散张量成像(diffusion tensor imaging,DTI)探讨首发儿童少年精神分裂症患者脑白质完整性与认知功能的关系。方法选择于2017年9月至2021年6月在新乡医学院第二附属医院儿童少年精神科住院的84例首发儿童少年精神分裂症患者作为研究组,选取与研究组相匹配的35例健康儿童少年为对照组;采用阳性与阴性症状量表(positive and negative syndrome scale,PANSS)评估患者精神症状;进行DTI扫描,采用基于纤维束骨架的空间统计学方法(tract-based spatial statistics,TBSS)测量脑白质纤维结构完整性,指标为各向异性分数(fractional anisotropy,fa);采用中文版精神分裂症认知功能成套测验-共识版(measurement and treatment research to improve cognition in schizophrenia consensus cognitive battery,MCCB)和Stroop色-词测验评估所有被试的认知功能。采用SPSS 26.0软件进行方差分析、独立样本t检验、Mann-Whitney U检验、Pearson相关分析。结果(1)研究组右上纵束(MNI:x=49,y=-40,z=31)和左皮质脊髓束(MNI:x=-27,y=-22,z=-19)fa值高于对照组,研究组两侧扣带回(MNI:x=-7,y=25,z=14;x=20,y=-50,z=25)和胼胝体辐射线枕部(MNI:x=-19,y=-50,z=21)fa值低于对照组,且均差异具有统计学意义(均Pfa值与数字广度呈负相关(r=-0.269,P=0.023);胼胝体辐射线枕部fa值与符号编码呈正相关(r=0.237,P=0.047);左下纵束fa值与Stroop颜色和迷宫得分呈负相关(r=-0.289,-0.275,P=0.010,0.020);右下纵束fa值与迷宫得分呈负相关(r=-0.254,P=0.032)。胼胝体辐射线枕部fa值与阳性症状分呈正相关(r=0.170,P=0.040)。结论首发儿童少年精神分裂症患者认知功能障碍可能与大脑白质完整性异常有关。

关键词：弥散张量成像脑白质完整性认知功能儿童少年精神分裂症

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Effects of continuous tracheal gas insufflation during pressure limited ventilation on pulmonary surfactant in rabbits with acute lung injury

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Chinese Medical Journal 2006年第17期119卷 1415-1420页

作者： ZHU Guang-fa ZHANG Wei ZONG Hua LIANG Ying Department of Respiratory Medicine Beijing Anzhen HospitalCapital University of Medical Science Beijing 100029 China

Background Pulmonary surfactant dysfunction may contribute to the development of ventilator induced lung injury （VILI）. Tracheal gas insuffiation （TGI） is a technique in which fresh gas is introduced into the trachea and augment ventilation by reducing the dead space of ventilatory system, reducing ventilatory pressures and tidal volume （VT） while maintaining constant partial arterial CO2 pressure （PaCO2）. We hypothesised that TGI limited peak inspiratory pressure （PIP） and VT and would minimize conventional mechanical ventilation （CMV） induced pulmonary surfactant dysfunction and thereby attenuate VILI in rabbits with acute lung injury （ALI）. Methods ALI was induced by intratracheal administration of lipopolysaccharide in anaesthetized, ventilated healthy adult rabbits randomly assigned to continuous TGI at 0.5 L/min （TGI group） or CMV group （n=8 for each group）, and subsequently ventilated with limited PIP and VT to maintain PaCO2 within 35 to 45 mmHg for 4 hours. Physiological dead space to VT ratio （VD/VT）, dynamic respiratory compliance （Cdyn） and partial arterial O2 pressure （PaO2） were monitored. After ventilation, lungs were analysed for total phospholipids （TPL）, total proteins （TP）, pulmonary surfactant small to large aggregates ratio （sa/LA） in bronchoalveolar lavage fluid （BALF） and for determination of alveolar volume density （Vv）, myeloperoxidase and interleukin （IL）-8. Results TGI resulted in significant （P〈0.05 or P〈0.01） decrease in PIP [（22.4±1.8） cmH20 vs （29.5±1.1） cmH2O], VT [（6.9±1.3） ml/kg vs （9.8±1.11） ml/kg], VD/VT [（32±5）% vs （46±2）%], TP [（109±22） mg/kg vs （187±25） mg/kg], sa/LA （2.5±0.4 vs 5.4±0.7）, myeloperoxidase [（6.2±0.5） U/g tissue vs （12.3±0.8） U/g tissue] and IL-8 [（987±106） ng/g tissue vs （24±3） mN/m] of BALF, and significant （P〈0.05） increase in Cdyn [（0.47±0.02） ml·cmH2O^-1·kg^-1 vs （0.31±0.02） ml·cmH2O^-1·kg^-1], PaO2 [（175±24） mmHg vs （135±26） mmHg], TPL/TP （52±8 vs 33±11） and Vv （0.65±0.05 vs 0.44±0.07） as compared with CMV

关键词： tracheal gas insufflation acute lung injury pulmonary surfactant ventilator induced lung injury mechanical ventilation

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Snake Model for the Extraction of Loess Shoulder-line from DEMs

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Journal of Mountain Science 2014年第6期11卷 1552-1559页

作者： YAN Shi-jiang TANG Guo'an LI fa-yuan ZHANG Lei Key laboratory of Virtual Geographic Environment Ministry of Education Nanjing Normal University School of Resource and Environmental Engineering Anhui University

Shoulder lines are the most important landform demarcations for geographical analysis,soil erosion modeling and land use planning in the Loess Plateau area of *** paper proposes an automatic,effective and accurate method of determining loess shoulder line from DEMs by integrating a hydrological D8 algorithm and a snake *** watershed boundary line is adopted as the initial contour which evolves to identify the exact position of loess shoulder-line by the guidance of an external force of snake model from *** show that the method overcomes the difficulties in both threshold selection for edge detection and the disconnecting issues in former extraction *** accuracy evaluation of shoulder-line maps from the two test sites of the loess plateau area show obvious improvements in the *** average contour matching distance of the new method is 12.0 m on 5 m resolution DEM,and shows improvement in the accuracy and *** comparisons of accuracy evaluations of the two test sites show that the snake model method performs better in the loess plain area than in the area with high gully density.

关键词：模型黄土高原提取方法蛇模型 DEM 肩线土地利用总体规划黄土高原地区土壤侵蚀模型

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滚动轴承压缩故障信号的特征代理与凸优化重构算法

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振动工程学报 2022年第2期35卷 434-445页

作者：林慧斌邓立发华南理工大学机械与汽车工程学院广东广州510640

压缩采样可以有效缓解机械状态监测数据存储和传输的压力,但是压缩数据的感知重构一直是个难点。针对滚动轴承压缩信号的故障特征提取问题,提出一种基于特征代理与凸优化算法的故障信号重构方法。分析了滚动轴承局部故障信号的稀疏和卷... 详细信息

压缩采样可以有效缓解机械状态监测数据存储和传输的压力,但是压缩数据的感知重构一直是个难点。针对滚动轴承压缩信号的故障特征提取问题,提出一种基于特征代理与凸优化算法的故障信号重构方法。分析了滚动轴承局部故障信号的稀疏和卷积特性,学习得到故障冲击模式。对压缩得到的轴承观测信号,构造包含冲击时刻特征的代理,并对代理建立目标优化函数,采用快速迭代收缩阈值算法(fast Iterative Shrinkage Threshold Algo⁃rithm,FISTA)直接从代理提取出稀疏系数,将学习模式与稀疏系数卷积重构出故障信号。与直接利用FISTA从压缩信号中提取冲击特征相比,所提方法在不降低求解精度的同时降低了计算复杂度。相比于常用的贪婪类重构算法,所提方法无需预先估计信号的稀疏度,且能得到全局最优解。通过滚动轴承仿真和实验信号进一步验证了所提方法的有效性。

关键词：故障诊断滚动轴承压缩感知特征重构

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绿肥植物对咖啡园节肢动物功能团多样性的影响

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江西农业学报 2024年第3期36卷 54-60页

作者：付兴飞胡发广李贵平李亚男黄家雄李亚麒喻好好杨旸云南省农业科学院热带亚热带经济作物研究所云南保山678000

为探讨绿肥植物对咖啡园节肢动物功能团多样性的影响,分别于2021年7月和11月采用目光搜寻法对常规种植(CK)、大翼豆种植(ML)、新诺顿豆种植(NW)3种类型咖啡园的节肢动物群落进行了调查,分析了各功能团的多样性和群落稳定性。结果表明:... 详细信息

为探讨绿肥植物对咖啡园节肢动物功能团多样性的影响,分别于2021年7月和11月采用目光搜寻法对常规种植(CK)、大翼豆种植(ML)、新诺顿豆种植(NW)3种类型咖啡园的节肢动物群落进行了调查,分析了各功能团的多样性和群落稳定性。结果表明:在常规种植咖啡园采集到节肢动物22种161头,大翼豆种植咖啡园采集节肢动物34种108头,新诺顿豆种植咖啡园采集节肢动物27种101头。绿肥种植模式咖啡园各功能团的Margalef、shannon-Wiener、Pielou指数均高于常规种植咖啡园捕食性功能团的,而常规种植咖啡园天敌功能团的Simpson指数显著高于绿肥种植模式咖啡园各功能团的;绿肥种植模式咖啡园节肢动物群落的Ss/Si和sa/Sp指数均高于常规种植咖啡园的。典型对应分析表明,绿肥种植模式咖啡园捕食性节肢动物的物种数和个体数更多;绿肥种植模式咖啡园节肢动物群落的稳定性更高,天敌与植食性害虫的相互制约关系更明显,更有利于有害生物的绿色防控。

关键词：绿肥节肢动物功能团多样性咖啡园

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Expression of NF-kappaB in rotavirus-induced damage to the liver and biliary tract in neonatal mice

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Hepatobiliary & Pancreatic Diseases International 2007年第2期6卷 188-193页

作者： Huang, Lei Gu, Wei-Zhong Si, Xin-Min Wei, Ming-fa Feng, Jie-Xiong Huazhong Univ Sci & Technol Dept Pediat Surg Tongji Hosp Wuhan 430030 Peoples R China Zhejiang Univ Sch Med Dept Pathol Childrens Hosp Hangzhou 310003 Peoples R China Wuhan Univ Renmin Hosp Dept Gastroenterol Wuhan 430060 Peoples R China

BACKGROUND: Biliary atresia, the etiology of which still remains unclear, occurs exclusively in newborns and most are infected with rotavirus. In this study, we aimed to investigate the histopathological patterns of different kinds of rotavirus in the liver and biliary tract of neonatal mice and the expression of NF-kappa B in the liver and biliary tract of infected mice. METHODS: Twenty-three adult mice (8 were male and 15 female) were divided into 8 breeding pairs, and each pair (I male and 2 females) was housed in a cage in a laminar flow hood. Newborn mice, 24-48 hours old were randomly divided into A, B and C groups. The A and B groups were respectively inoculated with MMU18006 and sa11 rotavirus through the intraperitoneal route, while group C as blank control was only inoculated with culture medium. The liver was dissected after 5, 10, 15, 21 and 28 days; the weight of each mouse and the histopathological patterns in the liver were recorded. The expression of NF-kappa B in the liver and intrahepatic bile ducts was detected by immunohistochemical staining and the expression intensity was analyzed with a GT-2 imaging instrument. RESULTS: The average increase in weight of infected mice was significantly slower than that of the normal control, while the growth rate of group A (injected with MMU18006 rotavirus) was slower than that of group B (sa11 rotavirus). In infected mice, the acute and chronic inflammation of liver and intra- and extra-hepatic bile ducts was more significant in group A. Stenosis was found in most intrahepatic bile ducts, and sporadically in extrahepatic bile ducts. The expression of NF-kappa B in infected mice was dramatically higher than that of the normal control, while the expression in group A was higher than in group B. CONCLUSIONS: Significant damage to the liver and biliary tract of neonatal mice can be induced by inoculating MMU18006 rotavirus through the intraperitoneal route, which is very similar to the pathology of biliary atresi

关键词： rotavirus biliary atresia NF-kappa B

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海面远距离目标运动属性判别方法

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电光与控制 2014年第1期21卷 15-17,90页

作者：杨士英花良发马飒飒空军预警学院黄陂士官学校武汉430345 军械工程学院军械技术研究所石家庄050003

基于临近空间平台的T1R1系统,以对海面远距离目标运动属性的快速判别为需求,提出了对目标运动属性的快速判别方法。该方法不用计算目标位置,仅需根据单侦察时差参数观测值的统计特征来判别目标的运动属性。仿真结果验证了该方法的有效性。

关键词：海面远距离目标运动属性时差临近空间平台

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Controlled Synthesis of Dendritic Polyaniline Fibers with Diameters from Nanosize to Submicrometersize

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Chinese Chemical Letters 2005年第11期16卷 1523-1526页

作者： Xiao Cong WANG Shu Jiang DING Jing CAO fa Lun WU Chen ZHOU Zhen Zhong YANG College of Science Tianjin University of Science and Technology Tianjin 300022 State Key Laboratory of Polymer Physics and Chemistry Institute of Chemistry Chinese Academy of Sciences Beijing 100080

Dendritic polyaniline nanofibers and submicrometer-sized fibers have been synthesized by chemical oxidative polymerization of aniline （An） doped with salicylic acid （sa）. The diameters of the fibers could be controlled easily from 30 to 400 nm by varying the concentration of aniline and salicylic acid at room temperature. Scanning electron microscopy （SEM） and typical transmission electron microscopy （TEM） were applied to investigate their morphologies. . Fourier transform infrared （FTIR） spectrum indicated that the state of the dendritic polyaniline fibers is emerialdine rather than solely the leucoemeraldine or permigraniline forms. The dendritic polyaniline fibers have potential applications as chemical sensors or actuators and neuron devices.

关键词： Dendritic polyaniline synthesis nanofiber.

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Herbivore-induced rice resistance against rice blast mediated by salicylic acid

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Insect Science 2020年第1期27卷 49-57页

作者： Kai-Li Zhang Qing-Song Liu Hou-Xiang Kang Xiao-Mei Liu Xiu-Ping Chen Yu-fa Peng Yun-He Li College of Environment and Plant Protection Hainan UniversityHaikouChina State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijingChina College of Life Sciences Xinyang Normal UniversityXinyangHenanChina

In agro-ecosystems,plants are important mediators of interactions between their associated herbivorous insects and microbes,and any change in plants induced by one species may lead to cascading effects on interactions with other ***,such effects are regulated by phytohormones such as jasmonic acid(JA)and salicylic acid(sa).Here,we investigated the tripartite interactions among rice plants,three insect herbivores(Chilo suppressalis,Cnaphalocrocis medinalis or Nilapai-vata lugens),and the causal agent of rice blast disease,the fungus Magnaporthe *** found that pre-infestation of rice by *** or *** but not by *** conferred resistance to *** *** and ***,insect infestation without fungal inoculation induced the accumulation of both JA and sa in rice *** contrast,infestation by *** increased JA levels but reduced sa *** exogenous application of sa but not of JA conferred resistance against *** results suggest that preinfestation by C suppressalis or *** conferred resistance against *** by increasing sa *** findings enhance our understanding of the interactions among rice plant,insects and pathogens,and provide valuable information for developing an ecologically sound strategy for controlling rice blast.

关键词： induced defense jasmonic acid plant-insect-pathogen interaction rice salicylic acid

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