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International Journal of Mental Health Promotion 2022年第3期24卷 425-437页

作者： seungju hyun Department of Psychology Korea Military AcademySeoul01805Korea

While the effect of self-esteem stability on life satisfaction is widely verified,it is not very known how coping strategies explain this *** present study focused on proactive coping,a preliminary step to minimize the impact of expected stressors,and a process of recognizing stressful events as challenges and actively managing ***,this study(N=280)examined whether proactive coping and perceived stress mediated the relationship between self-esteem stability and life satisfaction in a sequential *** results indicate that proactive coping and perceived stress sequentially mediated the relationship between self-esteem stability and life satisfaction,*** demonstrates that proactive coping and perceived stress are factors that link self-esteem and life ***,there was no direct effect between self-esteem and life *** findings suggest the need to consider combining proactive coping interventions to increase the effectiveness of a self-esteem stability promotion *** practical implications and suggestions for future research are also discussed.

关键词： Self-esteem stability proactive coping perceived stress life satisfaction

Could Military Commanders’ Good LeadershipInfluence Subordinates’ Smartphone Overdependence? A Serial Mediation Analysis

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International Journal of Mental Health Promotion 2023年第11期25卷 1187-1195页

作者： seungju hyun Xyle Ku Sungrok Kang Yoonyoung Choi Jaewon Ko hyunyup Lee Department of Psychology Korea Military AcademySeoul01805Korea Department of Psychology Seoul National UniversitySeoul08826Korea

Owing to the ubiquitous use of smartphones by soldiers, military researchers have an increasing interest in potentially problematicside effects such as smartphone overdependence. This raises a question regarding the psychological mechanisms underlying thepotentially self-damaging use of smartphones. Here, we address this question by analyzing how heterogeneity in commander’sgood leadership explains subordinate soldiers’ differences in self-control and smartphone use. Specifically, we found thatsubordinate soldiers who thought their commander's leadership was good were self-regulated, less dependent on smartphones,less stressed, and finally had good mental health. This result indicates that commander’s good leadership can be used toestimate whether subordinate soldiers exert control over their impulses and use their smartphones properly. Thus, the currentfindings help to identify external factors that lead to a better understanding of problematic smartphone use and can potentiallyhelp to design appropriate preventive mechanisms or interventions that target commander’s good leadership.

关键词： Military commander leadership smartphone overdependence soldier mental health

Compartmentalized regulation of organelle integrity in neurodegenerative diseases:lessons from the Drosophila motor neuron

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Neural Regeneration Research 2025年第1期20卷 195-196页

作者： hyun Sung Department of Neurology Johns Hopkins University School of MedicineBaltimoreMDUSA Medical Research Institute and Department of PharmacologyPusan National University School of MedicineYangsanRepublic of Korea

Neurons are highly polarized,morphologically asymmetric,and functionally compartmentalized cells that contain long axons extending from the cell *** this reason,their maintenance relies on spatiotemporal regulation of organelle distribution between the somatodendritic and axonal *** some organelles,such as mitochondria and smooth endoplasmic reticulum,are widely distributed throughout the neuron,others are segregated to either the somatodendritic or axonal *** example,Golgi outposts and acidified lysosomes are predominantly present in the somatodendritic domain and rarely distributed along the axon,whereas newly formed autophagosomes and synaptic vesicles are mainly distributed in the distal axon(Britt et al.,2016).

关键词： organelle regulation distribution

Brain age estimation:premise,promise,and problems

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Neural Regeneration Research 2025年第8期20卷 2313-2314页

作者： Jarrad Perron Ji hyun Ko Graduate Program in Biomedical Engineering Price Faculty of EngineeringUniversity of ManitobaWinnipegMBCanada PrairieNeuro Research Centre Kleysen Institute for Advanced MedicineHealth Sciences CentreWinnipegMBCanada Department of Human Anatomy and Cell Science Rady Faculty of Health SciencesUniversity of ManitobaWinnipegMBCanada

Premise:The com bined effects of modern healthcare practices which prolong lifespan and declining birthrates have created unprecedented changes in age demographics worldwide that are especially pronounced in Japan,South Korea,Europe,and North *** old age is the most significant predictor of dementia,global healthcare systems must rise to the challenge of providing care for those with neurodegenerative disorders.

关键词： estimation providing birth

Male metaplastic breast cancer with poor prognosis:A case report

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World Journal of Clinical Cases 2022年第15期10卷 4964-4970页

作者： hyun Yul Kim seungju Lee Dong-il Kim Chang Shin Jung Jee Yeon Kim Kyung Jin Nam Ki Seok Choo Youn Joo Jung Department of Surgery Pusan National University Yangsan HospitalPusan National University School of MedicineGyeongnam 50612South Korea Department of Pathology Pusan National University Yangsan HospitalPusan National University School of MedicineGyeongnam 50612South Korea Department of Radiology Pusan National University Yangsan HospitalPusan National University School of MedicineGyeongnam 50612South Korea

BACKGROUND Metaplastic breast cancer(MBC)is a rare subtype of breast *** constitute less than 1%of breast cancer cases and are much rarer in *** are few reports of MBC because of its ***,an aggressive type of cancer,is refractory to common treatment modalities of breast cancer and has a poor *** SUMMARY We report a case of MBC in a 78-year-old *** visited our clinic with a palpable mass on the left breast with no masses in the axillary *** had previously undergone robot-assisted laparoscopic radical prostatectomy for prostate cancer,but there was no family history of *** breast mass was visible on ultrasonography,mammography,and magnetic resonance imaging,and chest computed tomography revealed a lung mass in the posterior basal segment of the right lower *** patient was diagnosed with metaplastic carcinoma on core needle biopsy with lung *** mastectomy with sentinel lymph node biopsy and video-assisted segmentectomy of the right lung was ***,multiple metastases appeared 3 mo after surgery in the brain,chest,and abdomen,and the patient died 5 mo after the initial *** MBC is an aggressive and extremely rare breast cancer *** case reports are needed to determine the optimal treatment.

关键词： Breast neoplasm Male Triple-negative breast cancer Metaplastic breast cancer Adjuvant treatment Case report

Effects of Polymeric Stabilizers on the Synthesis of Gold Nanoparticles

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Journal of Materials Science & Technology 2014年第2期30卷 107-111页

作者： Eun Jung Kim Jeong hyun Yeum Jin hyun Choi Department of Advanced Organic Materials Science and Engineering Kyungpook National University Department of Bio-fibers and materials Science Kyungpook National University

Gold nanoparticles （AuNPs） stabilized with sodium alginate （SA）, glycol chitosan （GC）, polyvinyl alcohol （PVA）, and polyethyleneimine （PEI） were synthesized in aqueous solutions at room temperature. Different sizes and size distributions of AuNPs were obtained according to the polymeric stabilizers. The mean particle diameters of AuNPs synthesized with GC and PVA as stabilizers were about 5.1 and 5.3 nm, respectively, while those of AuNPs stabilized with SA and PEI were 8.4 and 10.8 nm, respectively. When SA was used, relatively large particles aggregated to form large clusters. In the case of GC, a number of small particles built up large clusters. When PVA was used, the size and the number of nanoperticles were estimated small with a low weight content of Au. For this reason, the PVA-stabilized AuNPs formed clusters with a small hydrodynamic size. The AuNPs synthesized in the aqueous solution of PEI without a reducing agent, sodium borohydride, were uniform in size and formed the smallest nanoclusters （67.4 nm）. In this case, the highest Au content was obtained. Sufficiently grown nanoparticles with a high Au content and a limited hydrodynamic size are considered to be suitable for a variety of applications.

关键词： Gold nanoparticles Sodium alginate Glycol chitosan Polyvinyl alcohol Polyethyleneimine

Anti-obesity Effects of Ginsenosides in High-Fat Diet-Fed Rats

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Chinese Journal of Integrative Medicine 2019年第12期25卷 895-901页

作者： hyun-Jung Park Ji hyun Kim Insop Shim Department of Physiology College of MedicineKyung Hee UniversitySeoul(130-701)Republic of Korea Department of Food Science&Biotechnology College of Science and EngineeringSuwon-si(16227)Republic of Korea

Objective: To examine the anti-obesity effects of ginsenosides in Korea Red Ginseng(KRG, Panax ginseng) in rats fed with a high-fat diet(HFD). Methods: Twenty-five 4-week-old obesity rats after receiving an HFD for 5 weeks;subsequently, they were additionally treated with ginsenosides Rb1, Rd, Rg1, or Re(10 mg/kg, intraperitoneal injection) for a further 3 weeks(n=5 in each group). The control rats were fed a normal diet. The food consumption, body weight, locomotor activity, serum lipids, adipose tissues, nitric oxide(NO) expression, leptin, neuropeptide Y(NPY), cholecystokinin(CCK) in the brains were measured. Results: In the HFD-fed rats, body weight, body fat mass, serum levels of leptin and NO were significantly higher than in the control rats(P<0.05 or P<0.01). However, the treatment of Rd, Re, and Rb1 markedly decreased body fat mass and body weight(P<0.05). The serum level of leptin and NO in ginsenoside-treated rats were markedly lower than the control group(P<0.01). The expression of NPY and CCK in the hypothalamic nuclei showed insignificant difference among groups. However, the expression of NPY immunoreactive neurons in the hypothalamus was significantly reduced in the Rb1-treated group(P<0.05). Conclusion: PD-type ginsenoside Rb1 from the crude saponins of KRG may be a useful compound for the treatment of obesity and related disorders through the modulation of peripheral and central appetite-regulating signals.

关键词： Panax ginseng ginsenosides hypothalamus obesity

Clinical features of gastric adenoma detected within 3 years after negative screening endoscopy in Korea

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Gastroenterology Report 2023年第1期11卷 406-411页

作者： hyun Young Kim Department of Internal Medicine Seoul National University Bundang HospitalSeongnam-siGyeonggi-doKorea

Background:Early detection and management of gastric adenoma are important for preventing gastric *** present study aimed to evaluate the predictors of missed gastric adenoma on screening endoscopy in Korea and identify the risk factors associated with interval precancerous gastric ***:All cases of gastric adenomas diagnosed via screening endoscopy between 2007 and 2019 were *** them,those who had undergone endoscopy within 3 years were included in the present *** gastric adenoma was defined as gastric adenoma diagnosed within 3 years after negative screening ***:In total,295 cases of gastric adenoma were *** these,95(32.2%)were missed gastric adenoma cases(mean age,60.6 years;average interval between final and index endoscopies,12.6months);the remaining 200(67.8%)were newly detected adenoma *** analysis revealed thatmale sex,endoscopist experience,observation time,and presence of gastric intestinalmetaplasia(pathologically proven)were associated with missed gastric *** analysis revealed that gastric intestinal metaplasia(odds ratio[OR],2.736;95%confidence interval[CI],1.320–5.667;P=0.007)and shorter observation time of the index screening endoscopy(B,0.011;OR,0.990;95%CI,0.986–0.993;P<0.001)were independent risk factors for missed gastric *** optimal cut-off for the observation time for detecting gastric adenoma was 3.53minutes(area under curve,0.738;95%CI,0.677–0.799;P<0.001).Conclusions:Gastric intestinal metaplasia is an indication of missed gastric ***,careful inspection of gastric mucosa with gastric intestinal metaplasia and proper observation time can lower the possibility of missing the gastric adenoma during screening.

关键词： gastric adenoma screening endoscopy gastric intestinal metaplasia observation time

A Study on Classification and Detection of Small Moths Using CNN Model

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Computers, Materials & Continua 2022年第4期71卷 1987-1998页

作者： Sang-hyun Lee Department of Computer Engineering Honam UniversityGwangsanguGwangju62399South Korea

Currently,there are many limitations to classify images of small *** addition,there are limitations such as error detection due to external factors,and there is also a disadvantage that it is difficult to accurately distinguish between various *** paper uses a convolutional neural network(CNN)algorithm to recognize and classify object images of very small moths and obtain precise data images.A convolution neural network algorithm is used for image data classification,and the classified image is transformed into image data to learn the topological structure of the *** improve the accuracy of the image classification and reduce the loss rate,a parameter for finding a fast-optimal point of image classification is set by a convolutional neural network and a pixel image as a *** a result of this study,we applied a convolution neural network algorithm to classify the images of very small moths by capturing precise images of the *** results showed that the accuracy of classification of very small moths was more than 90%.

关键词： Convolution neural network rectified linear unit activation function pooling feature map

A Study on Cascade R-CNN-Based Dangerous Goods Detection Using X-Ray Image

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Computers, Materials & Continua 2022年第11期73卷 4245-4260页

作者： Sang-hyun Lee Department of Computer Engineering Honam UniversityGwangsanguGwangju 62399Korea

X-ray inspection equipment is divided into small baggage inspection equipment and large cargo inspection *** the case of inspection using X-ray scanning equipment,it is possible to identify the contents of goods,unauthorized transport,or hidden goods in real-time by-passing cargo through X-rays without opening *** this paper,we propose a system for detecting dangerous objects in X-ray images using the Cascade Region-based Convolutional Neural Network(Cascade R-CNN)model,and the data used for learning consists of dangerous goods,storage media,firearms,and *** addition,to minimize the overfitting problem caused by the lack of data to be used for artificial intelligence(AI)training,data samples are increased by using the CP(copy-paste)algorithm on the existing *** also solves the data labeling problem by mixing supervised and semi-supervised *** four comparative models to be used in this study are Faster Regionbased Convolutional Neural Networks Residual2 Network-101(Faster R-CNN_Res2Net-101)supervised learning,Cascade R-CNN_Res2Net-101_supervised learning,Cascade Region-based Convolutional Neural Networks Composite Backbone Network V2(CBNetV2)Network-101(Cascade R-CNN_CBNetV2Net-101)_supervised learning,and Cascade RCNN_CBNetV2-101_semi-supervised learning which are then compared and *** a result of comparing the performance of the four models in this paper,in case of Cascade R-CNN_CBNetV2-101_semi-supervised learning,Average Precision(AP)(Intersection over Union(IoU)=0.5):0.7%,AP(IoU=0.75):1.0%than supervised learning,Recall:0.8%higher.

关键词： Cascade R-CNN model faster R-CNN model X-ray screening equipment Res2Net supervised learning semi-supervised learning