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Bilateral superficial cervical plexus block for parathyroidectomy during pregnancy:A case report

World Journal of Clinical Cases 2022年第13期10卷 4153-4160页

作者： Jun-Young chung Yo Seob Lee seung Yeon Pyeon Sang-Ah Han Hyub Huh Department of Anesthesiology and Pain Medicine Kyung Hee University Hospital at GangdongCollege of MedicineKyung Hee UniversitySeoul 05278South Korea Department of Obstetrics&Gynecology Kyung Hee University Hospital at GangdongCollege of MedicineKyung Hee UniversitySeoul 05278South Korea Department of Surgery Kyung Hee University Hospital at GangdongCollege of MedicineKyung Hee UniversitySeoul 05278South Korea

BACKGROUND Primary hyperparathyroidism(PHPT)is the most common cause of pregnancyrelated *** can cause maternal and fetal complications in pregnant *** anesthesia for non-obstetric surgery in pregnant women is associated with maternal hazards and concerns regarding long-term neonatal neurocognitive *** removal of the lesion in mid-pregnancy is currently the primary treatment option for pregnant patients with ***,the blood calcium concentration at which surgery should be considered remains under discussion due to the risk of *** SUMMARY A 31-year-old nulliparous woman at 11 wk of gestation was admitted to our hospital for *** patient had a history of intrauterine fetal death with unknown etiology at 16 wk of gestation 1 year *** blood test results showed that the serum calcium level was elevated to 12.9 mg/dL,and the parathyroid hormone level was elevated to 157 pg/*** a neck ultrasound,it revealed a 0.8 cm×1.5 cm sized oval,hypoechoic mass in the upper posterior of the left thyroid gland,which was compatible with parathyroid *** cervical plexus block(SCPB)for parathyroidectomy was *** surgery,the obstetrician checked the status of the fetus,and there were no abnormal *** then her calcium level returned to normal values after one week of surgery and a healthy male neonate of 2910 g was delivered vaginally at 38 wk of *** Our case suggests that SCPB can be an anesthetic option for parathyroidectomy during the first trimester of pregnancy.

关键词： Bilateral superficial cervical plexus block Hypercalcemia Parathyroid adenoma Parathyroidectomy Pregnancy Case report

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Application of response surface method for optimal transfer conditions of multi-layer ceramic capacitor alignment system

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Journal of Central South University 2011年第3期18卷 726-730页

作者： PARK Su-seong KIM Jae-min chung Won-jee SHIN O-chul School of Mechatronics Changwon National University

The multi-layer ceramic capacitor (MLCC) alignment system aims at the inter-process automation between the first and the second plastic *** a result of testing performance verification of MLCC alignment system,the average alignment rates are 95% for 3216 chip,88.5% for 2012 chip and 90.8% for 3818 *** MLCC alignment system can be accepted for practical use because the average manual alignment is just 80%.In other words,the developed MLCC alignment system has been upgraded to a great extent,compared with manual *** on the successfully developed MLCC alignment system,the optimal transfer conditions have been explored by using *** simulations using ADAMS has been performed according to the cube model of *** using miniTAB,the model of response surface has been established based on the simulation *** optimal conditions resulted from the response optimization tool of miniTAB has been verified by being assigned to the prototype of MLCC alignment system.

关键词： multi-layer ceramic capacitor (MLCC) alignment system response surface method (RSM) miniTAB ADAMS

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Asymmetric optical camouflage:tuneable reflective colour accompanied by the optical Janus effect

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Light(Science & Applications) 2020年第1期9卷 325-334页

作者： Taehyun Kim Eui-Sang Yu Young-Gyu Bae Jongsu Lee In Soo Kim Seok chung seung-Yeol Lee Yong-Sang Ryu Sensor System Research Center Korea Institute of Science and TechnologySeoul 02792Republic of Korea Department of Micro/Nano Systems Korea UniversitySeoul 02841Republic of Korea School of Electronic and Electrical Engineering Kyungpook National UniversityDaegu 41566Republic of Korea Nanophotonics Research Center Korea Institute of Science and TechnologySeoul 02792Republic of Korea School of Mechanical Engineering Korea UniversitySeoul 02841Republic of Korea

Going beyond an improved colour gamut,an asymmetric colour contrast,which depends on the viewing direction,and its ability to readily deliver information could create opportunities for a wide range of applications,such as nextgeneration optical switches,colour displays,and security features in anti-counterfeiting ***,we propose a simple Fabry–Perot etalon architecture capable of generating viewing-direction-sensitive colour contrasts and encrypting pre-inscribed information upon immersion in particular solvents(optical camouflage).Based on the experimental verification of the theoretical modelling,we have discovered a completely new and exotic optical phenomenon involving a tuneable colour switch for viewing-direction-dependent information delivery,which we define as asymmetric optical camouflage.

关键词： asymmetric generating readily

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Comparison of efficacy and safety between standard-dose and modified-dose FOLFIRINOX as a first-line treatment of pancreatic cancer

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World Journal of Gastrointestinal Oncology 2018年第11期10卷 421-430页

作者： Huapyong Kang Jung Hyun Jo Hee seung Lee Moon Jae chung seungmin Bang seung Woo Park Si Young Song Jeong Youp Park Division of Gastroenterology Department of Internal Medicine Yonsei University College of Medicine

AIM To directly compare the efficacy and toxicity of standarddose FOLFIRINOX(sFOLFIRINOX) and modified-dose FOLFIRINOX(mFOLFIRINOX, 75% of standard-dose) for pancreatic *** One hundred and thirty pancreatic cancer patients who received sFOLFIRINOX(n = 88) or mFOLFIRINOX(n = 42) as their first-line chemotherapy from January 2013 to July 2017 were retrospectively reviewed. For efficacy analysis, the objective response rate(ORR),disease control rate(DCR), progression-free survival(PFS), and overall survival(OS) were evaluated and compared using Pearson's chi-square test, Kaplan-Meier plot and log-rank test. The adverse events(AEs) were evaluated, and severe(≥ grade 3) AEs rates of the two groups were compared for toxicity *** The mFOLFIRINOX group included more female patients(30.7% vs 57.1%; P = 0.004) and older patients [age(median), 57 vs 63.5; P = 0.018] than the sFOLFIRINOX group. In the efficacy analysis, the ORR and DCR were not significantly different between the two groups(ORR: 39.8% vs 35.7%; P = 0.656; DCR: 80.7% vs 83.3%; P = 0.716). The median PFS and OS were also not different between the groups(PFS: 8.7 mo vs 8.1 mo, P = 0.272; OS: 13.9 mo vs 13.7 mo, P = 0.476). In the safety analysis with severe AEs, the rates of neutropenia(83.0% vs 66.7%; P = 0.044), anorexia(48.9% vs 28.6%; P = 0.029) and diarrhea(13.6% vs 0.0%; P = 0.009) were markedly lower in the mFOLFIRINOX *** m FOLFIRINOX showed comparable efficacy but better safety compared to sFOLFIRINOX. If clinically necessary, initiating FOLFIRINOX with 75% of the standard-dose can alleviate toxicity concerns without compromising efficacy.

关键词： Dose modification Adverse event Pancreatic cancer Adenocarcinoma FOLFIRINOX Chemotherapy

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Early treadmill exercise increases macrophage migration inhibitory factor expression after cerebral ischemia/reperfusion

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Neural Regeneration Research 2019年第7期14卷 1230-1236页

作者： min Cheol Chang Chae Ri Park seung Hwa Rhie Woo Hyun Shim Dae Yul Kim Department of Rehabilitation Medicine College of MedicineYeungnam University Asan Institute for Life Sciences Asan Medical CenterUniversity of Ulsan College of Medicine Department of Rehabilitation Medicine Asan Medical CenterUniversity of Ulsan College of Medicine Department of Radiology Asan Medical CenterUniversity of Ulsan College of Medicine

The neuroprotective function of macrophage migration inhibitory factor(MIF) in ischemic stroke was rarely *** study aimed to investigate the effects of early treadmill exercise on recovery from ischemic stroke and to determine whether these effects are associated with the expression levels of MIF and brain-derived neurotrophic factor(BDNF) in the ischemic area.A total of 40 male Sprague-Dawley rats were randomly assigned to the ischemia and exercise group [middle cerebral artery occlusion(MCAO)-Ex,n = 10),ischemia and sedentary group(MCAO-St,n = 10),sham-surgery and exercise group(Sham-Ex,n= 10),or sham-surgery and sedentary group(Sham-St,n = 10).The MCAO-Ex and MCAO-St groups were subjected to MCAO for 60 minutes,whereas the Sham-Ex and Sham-St groups were subjected to an identical operation without *** in the MCAO-Ex and Sham-Ex groups then ran on a treadmill for 30 minutes once a day for 5 consecutive *** reperfusion,the hanging time tested by the wire hang test was longer and the relative fractional anisotropy determined by MRI was higher in the peri-infarct region of the MCAO-Ex group compared with the MCAO-St *** expression levels of MIF and BDNF in the peri-infarct region were upregulated in the MCAO-Ex *** MIF and BDNF levels were positively correlated with relative fractional anisotropy changes in the peri-infarct *** was no significant difference in the levels of MIF and BDNF in the peri-infarct region between the Sham-Ex and Sham-St *** study demonstrated that early exercise(initiated 48 hours after the MCAO) could improve motor and neuronal recovery after ischemic ***,the increased levels of MIF and BDNF in the peri-infarct region(penumbra) may be one of the mechanisms of enhanced neurological function *** experiments were approved by the Institutional Animal Care and Use Committee in Asan Medical Center in South Korea(2016-12-126).

关键词： ischemic stroke early exercise macrophage migration inhibitory factor brain-derived neurotrophic factor motor recovery neural regeneration

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Exophytic inflammatory myofibroblastic tumor of the stomach in an adult woman:A rare cause of hemoperitoneum

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World Journal of Gastroenterology 2008年第1期14卷 136-139页

作者： Seong-Heum Park Jong-Han Kim Byung Wook min Tae Jin Song Gil Soo Son seung Joo Kim Sang Woo Lee Hwan-Hoon chung Ju Han Lee Jun Won Um Department of Surgery Korea University College of Medicine 126-1 5-Ga Anam-Dong Sungbuk-Gu Seoul 136-705 Korea Department of Internal Medicine Korea University College of Medicine 126-1 5-Ga Anam-Dong Sungbuk-Gu Seoul 136-705 Korea Department of Radiology Korea University College of Medicine 126-1 5-Ga Anam-Dong Sungbuk-Gu Seoul 136-705 Korea Department of Pathology Korea University College of Medicine 126-1 5-Ga Anam-Dong Sungbuk-Gu Seoul 136-705 Korea

Inflammatory myofibroblastic tumor （INT） of the stomach in adults is extremely rare, with unpredictable prognosis. We present a 55-year-old woman with a gastric IMT. She experienced sudden abdominal pain 4 d previously. Physical examination showed mild abdominal tenderness in the hypogastrium, but no palpable abnormal abdominal mass. Abdominal CT showed a mass of approximately 8 cm in the gastrocolic ligament. On laparoscopic exploration, unexpected hemoperitoneum of approximately 1.5 L of blood was found, and an exophytic gastric mass of approximately 10 cm, appeared from the anterior wall of the gastric body along the greater curvature. Laparoscopy further showed that non- clotting blood in the abdominal cavity seemed to be from the gastric tumor. After conversion to open surgery for more precise evaluation of the cause of hemoperitoneum and the large friable tumor, gastric wedge resection, including the tumor, was conducted. The final diagnosis was consistent with IMT that originated from the gastric wall.

关键词： Stomach disease Stomach neoplasms Hemoperitoneum Myofibroma Granuloma Plasma cell Stomach surgery

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Fabrication of two-layer flexible copper clad laminate by electroless-Cu plating on surface modified polyimide

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中国有色金属学会会刊：英文版 2009年第4期19卷 970-974页

作者： Soo-min HWANG Jun-Hyung LIM Chang-min LEE Eui-Cheol PARK Jun-Hyuk CHOI Jinho JOO Hoo-Jeong LEE seung-Boo JUNG School of Advanced Materials Science and Engineering Sungkyunkwan University

A flexible copper clad laminate(FCCL) was fabricated using electroless-and electro-Cu plating processes and the effects of pre-treatment time on the adhesion strength of the FCCL were evaluated based on interfacial *** neutralization and catalyst time were varied in the range of 0-20 min and 0.1-10 min,respectively,and the interfacial condition of the FCCL was characterized by atomic force microscopy(AFM) and X-ray photoelectron spectroscopy(XPS).It is observed that the peel strength increases significantly as the neutralization and catalyst time *** strength as high as 7.2-7.3 N/cm is obtained as the neutralization and catalyst time increase up to 20 min and 10 min,respectively,which is comparable to the strength achieved by the conventional laminating and sputtering *** improvements are probably due to an increase in the surface roughness of polyimide(PI),the activated surface condition,and the adsorption of palladium ions/atoms(Pd) on the PI surface which act as nucleation sites for Cu.

关键词：聚酰亚胺表面改性化学制备层压板铜电镀铜箔软性 X射线光电子能谱

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Treatment satisfaction after I year high-power potassiumtitanyl-phosphate photoselective vaporization of the prostate

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Asian Journal of Andrology 2010年第5期12卷 728-734页

作者： Ja Hyeon Ku min Chul Cho Hyeong Seok Kim Jae-seung Paick Soo Woong Kim Department of Urology Seoul National University Hospital Seoul 100-744 Korea

To investigate the factors that influence treatment satisfaction after high-power potassium-titanyl-phosphate （KTP） laser vaporization of the prostate, we compared the characteristics between patients who were satisfied and those who were not satisfied. In all, 97 patients aged between 53-82 years （median age 67 years） underwent high-power KTP laser vaporization of the prostate for lower urinary tract symptoms due to benign prostatic hyperplasia. At 12 months postoperatively, 60 patients were satisfied with the treatment, whereas 37 were dissatisfied. Although there were no differences in International Prostate Symptom Score （IPSS） values at baseline, the satisfied group scored better in total IPSS at 1, 3, 6, and 12 months postoperatively （P 〈 0.05）. At baseline, the maximum flow rate （Qmax） was lower in the dissatisfied group and remained low throughout the follow-up period, with the exception of 1 month postoperatively （P 〈 0.05）, compared with the satisfied group. There were no differences in other objective data between the two groups, including post-void residual and the number of voids based on the frequency-volume charts. In a multivariate model, a higher bladder contractility index was associated with a greater likelihood of treatment satisfaction 12 months after high-power KTP laser vaporization （odds ratio 1.024, 95% confidence interval 1.001-1.048, P 〈 0.05）. Patients who were not satisfied following the surgery had a smaller improvement in subjective symptoms and Qmax. In addition, our findings suggest that the relative risk of treatment dissatisfaction following high-power KTP laser vaporization was increased in patients with weak detrusor contractility.

关键词： benign prostatic hyperplasia potassium-titanyl-phosphate prostate satisfaction vaporization

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Characterization of flexible copper laminates fabricated by Cu electro-plating process

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中国有色金属学会会刊：英文版 2009年第4期19卷 965-969页

作者： Chang-min LEE Jun-Hyung LIM Soo-min HWANG Eui-Cheol PARK Jong-Hyun SHIM Jin-Hyun PARK Jinho JOO seung-Boo JUNG School of Advanced Materials Science and Engineering Sungkyunkwan University

Flexible copper clad laminates(FCCLs) were fabricated using the electro-plating process and the combined effect of the current density and plating time on their surface morphology,texture,hardness,electrical resistivity and folding behavior was *** achieve Cu layers with similar thicknesses,the current density was varied in the range of 0.2-3 A/dm2 and the plating time was controlled in the range of 0.5-7.5 h to compensate for the variation of the current *** surface morphology,hardness,and folding behavior were characterized by atomic force microscopy,nanoindentation technique and Massachusett Institute of Technology folding endurance test,*** X-ray diffraction patterns indicated that the Cu phase was formed without any secondary phases;however,the preferred orientation changed from(220) to(111) as the current density increased over 1 A/*** addition,it was observed that the root-mean-square and hardness values decreased when the current density increased and the plating time decreased *** electrical resistivity was as low as approximately 21 nΩ·m and the number of cycles without failure in the folding test was over 15 000,which were comparable to those of commercial FCCLs.

关键词：电镀工艺层压板铜层制备表征电流密度原子力显微镜纳米压痕技术

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What is the most cost-effective strategy to screen for second primary colorectal cancers in male cancer survivors in Korea?

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World Journal of Gastroenterology 2009年第25期15卷 3153-3160页

作者： Sang min Park Sun-Young Kim Craig C Earle seung-Yong Jeong Young Ho Yun National Cancer Center Goyang Department of Population and International Health Harvard School of Public Health Department of Family Medicine Seoul National University HospitalSeoul National University College of Medicine Program in Health Decision Science Department of Health Policy and ManagementHarvard School of Public Health Division of Population Sciences Department of Medical OncologyDana-Farber Cancer InstituteHarvard Medical School Department of Surgery Seoul National University HospitalSeoul National University College of Medicine Division of Cancer Control National Cancer Center

AIM： To identify a cost-effective strategy of second primary colorectal cancer （CRC） screening for cancer survivors in Korea using a decision-analytic model. METHODS： A Markov model estimated the clinical and economic consequences of a simulated 50-year- old male cancer survivors＇ cohort, and we compared the results of eight screening strategies： no screening, fecal occult blood test （FOBT） annually, FOBT every 2 years, sigmoidoscopy every 5 years, double contrast barium enema every 5 years, and colonoscopy every 10 years （COL10）, every 5 years （COL5）, and every 3 years （COL3）. We included only direct medical costs, and our main outcome measures were discounted lifetime costs, life expectancy, and incremental cost- effectiveness ratio （ICER）. RESULTS： In the base-case analysis, the non-dominat- ed strategies in cancer survivors were COL5, and COL3. The ICER for COL3 in cancer survivors was $5593/life- year saved （LYS）, and did not exceed $10000/LYS in one-way sensitivity analyses. If the risk of CRC in can- cer survivors is at least two times higher than that in the general population, COL5 had an ICER of less than $10500/LYS among both good and poor prognosis of index cancer. If the age of cancer survivors starting CRC screening was decreased to 40 years, the ICER of COL5 was tess than $7400/LYS regardless of screening compliance. CONCLUSION： Our study suggests that more strict and frequent recommendations for colonoscopy such as COL5 and COL3 could be considered as economically reasonable second primary CRC screening strategies for Korean male cancer survivors.

关键词： Cost-effectiveness Second primary colorectal cancer Screening Cancer survivor

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