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Journal of Geriatric Cardiology 2016年第10期13卷 824-829页

作者： Woong Gil Choi Soo Hyun Kim seung-Woon Rha Kang-Yin CHEN Yong-Jian LI Byoung Geol Choi Se Yeon Choi Jin Won Kim Eung Ju Kim Chang Gyu Park hong Seog Seo Dong Joo Oh Department of Internal Medicine School of Medicine Kunkuk University Chungbuk South Korea Cardiovascular Center Korea University Guro Hospital Seoul South Korea Department of Cardiology the Second Hospital of Tianjin Medical University Tianjin China Department of Cardiology Nankai Hospital Tianjin Medical University Tianjin China

Background Smoking and other risk factors have been well known as important factors of variant angina or coronary artery spasm （CAS）. However, clinical features related to age on coronary artery spasm have been rarely evaluated. Methods We evaluated 3155 consecutive patients with insignificant coronary artery lesion. Patients underwent Acetylcholine （Ach） provocation test for induction of CAS. CAS was defined as 〉 70% luminal narrowing of coronary arteries during Ach provocation test. The results of Ach provocation test were compared among age groups; 〈 45 years （Group 1）, 45-54 years （Group 2）, 55-64 years （Group 3）, and 〉_ 65 years （Group 4）. Results Older patients had higher incidence of hypertension, diabetes, but lower incidence rate of current smoking, male sex compared with younger patients. Positive Ach provocation test finding was frequently showed with aging （47.36% vs. 58.3% vs. 62.6% vs. 61.5%; P 〈 0.001）. Multivariate logistic analysis showed that age, male, and myocardial bridge were independent predictors of CAS induced by Ach provocation test. Conclusion Our present study showed that old age was independent predictor for Ach-induced significant coronary artery spasm.

关键词： Acetylcholine Age factor Coronary vasospasm

International Nuclear Medicine Consensus on the Clinical Use of Amyloid Positron Emission Tomography in Alzheimer’s Disease

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Phenomics 2023年第4期3卷 375-389页

作者： Mei Tian Chuantao Zuo Ali Cahid Civelek Ignasi Carrio Yasuyoshi Watanabe Keon wook Kang Koji Murakami Valentina Garibotto John OPrior Henryk Barthel Yihui Guan Jiaying Lu Rui Zhou Chentao Jin Shuang Wu Xiaohui Zhang Yan Zhong hong Zhang Molecular Imaging-Based Precision Medicine Task Group of A3(China-Japan-Korea)Foresight Program PET Center Huashan HospitalFudan UniversityShanghai 200235China Human Phenome Institute Fudan UniversityShanghai 201203China Department of Nuclear Medicine and PET Center The Second Affiliated Hospital of Zhejiang University School of MedicineHangzhou 310009China National Center for Neurological Disorders and National Clinical Research Center for Aging and Medicine Huashan HospitalFudan UniversityShanghai 200040China Department of Radiology and Radiological Science Division of Nuclear Medicine and Molecular ImagingJohns Hopkins MedicineBaltimore 21287USA Department of Nuclear Medicine Hospital Sant PauAutonomous University of BarcelonaBarcelona 08025Spain Laboratory for Pathophysiological and Health Science RIKEN Center for Biosystems Dynamics ResearchKobeHyogo 650‑0047Japan Department of Nuclear Medicine Seoul National University College of MedicineSeoul 03080Korea Department of Radiology Juntendo University HospitalTokyo 113‑8431Japan Diagnostic Department University Hospitals of Geneva and NIMTlabUniversity of GenevaGeneva 1205Switzerland Department of Nuclear Medicine and Molecular Imaging Lausanne University HospitalLausanne 1011Switzerland Department of Nuclear Medicine Leipzig University Medical CenterLeipzig 04103Germany Key Laboratory of Medical Molecular Imaging of Zhejiang Province Hangzhou 310009China The College of Biomedical Engineering and Instrument Science of Zhejiang University Hangzhou 310007China Key Laboratory for Biomedical Engineering of Ministry of Education Zhejiang UniversityHangzhou 310007China 不详

Alzheimer’s disease(AD)is the main cause of dementia,with its diagnosis and management remaining *** positron emission tomography(PET)has become increasingly important in medical practice for patients with *** integrate and update previous guidelines in the field,a task group of experts of several disciplines from multiple countries was assembled,and they revised and approved the content related to the application of amyloid PET in the medical settings of cognitively impaired individuals,focusing on clinical scenarios,patient preparation,administered activities,as well as image acquisition,processing,interpretation and *** addition,expert opinions,practices,and protocols of prominent research institutions performing research on amyloid PET of dementia are *** the increasing availability of amyloid PET imaging,a complete and standard pipeline for the entire examination process is essential for clinical *** international consensus and practice guideline will help to promote proper clinical use of amyloid PET imaging in patients with AD.

关键词： Positron emission tomography(PET) Alzheimer’s disease Amyloid Brain imaging Expert consensus

中国古文献中所看到的古代建筑结构力学认识研究

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中国文物科学研究 2014年第3期 59-61页

作者：金德文玄胜旭韩国国立文化财研究所建筑文化财研究室

考察古代人的结构力学认识,是对古建筑结构的分析及解释必不可少的研究之一。因为与现代建筑结构不同,古代建筑结构主要取决于当时工匠们的经验与直观判断。古代人对结构力学的认识概念,我们从中国古文献中可以看到。通过本研究发现,古... 详细信息

考察古代人的结构力学认识,是对古建筑结构的分析及解释必不可少的研究之一。因为与现代建筑结构不同,古代建筑结构主要取决于当时工匠们的经验与直观判断。古代人对结构力学的认识概念,我们从中国古文献中可以看到。通过本研究发现,古代人已经有对力与荷重的力学认识以及古建筑的对称结构就是从古代力学的平衡概念出发而发展的。

关键词：建筑结构力量荷重力的平衡力学认识

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异常钙钛矿氧化物结构规律研究

异常钙钛矿氧化物结构规律研究

Social Agents with Strategic Coalition Generalize well in the IPD Game

中国化学会第七届全国结构化学学术会议

作者： Man-Rong Li seung-Tae hong David Walker Martha Greenblatt MOE Key Laboratory of Bioinorganic and Synthetic Chemistry School of ChemistrySun Yat-sen University CR&D LG Chem Research Park Lamont Doherty Earth Observatory Columbia University

多功能钙钛矿氧化物因其多样性的结构和优异的物化性能,日益成为结构化学和材料科学领域的研究热点。常见的材料是ABO3型简单钙钛矿和ABB’O6型双钙钛矿,其结构和成相规律已广为研究,理想情况下A位为12配位的较大离子而B/B’位为6(八面...

多功能钙钛矿氧化物因其多样性的结构和优异的物化性能,日益成为结构化学和材料科学领域的研究热点。常见的材料是ABO3型简单钙钛矿和ABB’O6型双钙钛矿,其结构和成相规律已广为研究,理想情况下A位为12配位的较大离子而B/B’位为6(八面体)配位的小离子。随着A位离子变小,其结构随容忍因子(Tolerance factor,t)降低而发生畸变,对称性依次从六角变为立方、四方、菱方、单斜等。当A位和

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Social Agents with Strategic Coalition Generalize well in th...

Risk factors affecting pancreatic fistulas after pancreaticoduodenectomy

International Congress of Mathematicians 2002 Satellite Conference on Game Theory and Applications(ICM 2002 GTA)

作者： seung-Ryong Yang Sung-Bae Cho Department of Computer Science Yonsei University 134 Shinchon-dongSudaemoon-kuSeoul 120-749Korea

＜正＞The Iterated Prisoner’s Dilemma（IPD） game is one of the modeling methods which reflect social interactions,economic activities,international relationship, and so *** researchers have been worked in this field since Axelrod proposed IPD game between two players,but most of them focused on restricted topics like individual strategies of players and payoff variances among *** this paper we exploit the strategic coalition of individuals in IPD *** can be formed depending on several conditions,and decision making in coalition is better than individual’s *** use this technique to improve the generalization ability of player’s *** results also reveal the relationships of coalition with the number of players and payoff functions.

关键词： Prisoner’s Dilemma Coalition Co-evolution Multi-Agent Strategic Learning

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World Journal of Gastroenterology 2008年第45期14卷 6970-6974页

作者： Yun-Mee Choe Keon-Young Lee Cheong-Ah Oh Joung-Bum Lee Sun Keun Choi Yoon-Seok Hur Sei-Joong Kim Young Up Cho seung-Ik Ahn Kee-Chun hong Seok-Hwan Shin Kyung-Rae Kim Department of Surgery Inha University Hospital

AIM: To analyze the risk factors of pancreatic leakage after ***: We retrospectively reviewed 172 consecutive patients who had undergone pancreatico-duodenectomy at Inha University Hospital between April 1996 and March 2006. We analyzed the pancreatic fistula rate according to the clinical characteristics, the pathologic and laboratory findings, and the anastomotic ***: The incidence of developing pancreatic fistulas in patients older than 60 years of age was 21.7% (25/115), while the incidence was 8.8% (5/57) for younger patients; the difference was significant (P = 0.03). Patients with a dilated pancreatic duct had a lower rate of post-operative pancreatic fistulas than patients with a non-dilated duct (P = 0.001). Other factors, including clinical features, anastomotic methods, and pathologic diagnosis, did not show any statistical difference. CONCLUSION: Our study demonstrated that pancreatic fistulas are related to age and a dilated pancreatic duct. The surgeon must take these risk factors into consideration when performing a pancre-aticoduodenectomy.

关键词： Pancreaticoduodenectomy Pancreatic fistula Pancreatic leakage

Assessment of scoring systems for acute-on-chronic liver failure at predicting short-term mortality in patients with alcoholic hepatitis

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World Journal of Gastroenterology 2016年第41期22卷 9205-9213页

作者： Hee Yeon Kim Chang wook Kim Tae Yeob Kim Do Seon Song Dong Hyun Sinn Eileen L Yoon Young Kul Jung Ki Tae Suk Sang Soo Lee Chang Hyeong Lee Tae Hun Kim Jeong Han Kim Hyung Joon Yim Sung Eun Kim Soon Koo Baik Byung Seok Lee Jae Young Jang Young Seok Kim Sang Gyune Kim Jin Mo Yang Joo Hyun Sohn Heon Ju Lee seung Ha Park Eun Hee Choi Dong Joon Kim Korean Acute-on-Chronic Liver Failure Study Group Department of Internal Medicine College of MedicineThe Catholic University of KoreaSeoul 06591South Kerea Institute of Medical Science Hanyang UniversitySeoul 04763South Kerea Department of Internal Medicine Samsung Medical CenterSeoul 06351South Kerea Department of Internal Medicine Inje University Sanggye Paik HospitalSeoul 01757South Kerea Department of Internal Medicine Korea University Ansan HospitalAnsan 15355South Korea Department of Internal Medicine Hallym University Chuncheon Sacred Heart HospitalChuncheon 24253South Kerea Department of Internal Medicine Gyeongsang National University HospitalJinju 52727South Kerea Department of Internal Medicine Catholic University of Daegu School of MedicineDaegu 42472South Kerea Department of Internal Medicine Ewha Womans University School of MedicineSeoul 07985South Kerea Department of Internal Medicine Konkuk University School of MedicineSeoul 05030South Kerea Department of Internal Medicine Hallym University Sacred Heart HospitalAnyang 14068South Kerea Department of Internal Medicine Yonsei University Wonju College of MedicineWonju 26426South Kerea Department of Internal Medicine Chungnam National UniversitySchool of MedicineDaejeon 35015South Kerea Department of Internal Medicine Soonchunhyang University College of MedicineSeoul 04401South Kerea Department of Internal Medicine Soonchunhyang University Bucheon HospitalBucheon 14584South Kerea Department of Internal Medicine Hanyang University Guri HospitalGuri 11923South Kerea Department of Internal Medicine Yeungnam University College of MedicineDaegu 42415South Kerea Department of Internal Medicine Inje University Haeundae Paik-HospitalInje University College of MedicineBusan 48108South Kerea Institute of Lifestyle Medicine Yonsei University Wonju College of MedicineWonju 26426South Kerea 不详

AIM To assess the performance of proposed scores specific for acute-on-chronic liver failure in predicting shortterm mortality among patients with alcoholic *** We retrospectively collected data from 264 patients with clinically diagnosed alcoholic hepatitis from January to December 2013 at 21 academic hospitals in Korea. The performance for predicting short-term mortality was calculated for Chronic Liver FailureSequential Organ Failure Assessment(CLIF-SOFA), CLIF Consortium Organ Failure score(CLIF-C OFs), Maddrey'sdiscriminant function(DF), age, bilirubin, international normalized ratio and creatinine score(ABIC), Glasgow Alcoholic Hepatitis Score(GAHS), model for end-stage liver disease(MELD), and *** Of 264 patients, 32(12%) patients died within 28 d. The area under receiver operating characteristic curve of CLIF-SOFA, CLIF-C OFs, DF, ABIC, GAHS, MELD, and MELD-Na was 0.86(0.81-0.90), 0.89(0.84-0.92), 0.79(0.74-0.84), 0.78(0.72-0.83), 0.81(0.76-0.86), 0.83(0.78-0.88), and 0.83(0.78-0.88), respectively, for 28-d mortality. The performance of CLIF-SOFA had no statistically significant differences for 28-d mortality. The performance of CLIF-C OFs was superior to that of DF, ABIC, and GAHS, while comparable to that of MELD and MELD-Na in predicting 28-d mortality. A CLIF-SOFA score of 8 had 78.1% sensitivity and 79.7% specificity, and CLIF-C OFs of 10 had 68.8% sensitivity and 91.4% specificity for predicting 28-d *** CLIF-SOFA and CLIF-C OF scores performed well, with comparable predictive ability for short-term mortality compared to the commonly used scoring systems in patients with alcoholic hepatitis.

关键词： Acute-on-chronic liver failure Alcoholic hepatitis Mortality Prognosis Scoring system

Functional dissection of parabrachial substrates in processing nociceptive information

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Zoological Research 2024年第3期45卷 633-647页

作者： Jin Ke Wei-Cheng Lu Hai-Yang Jing Shen Qian Sun-wook Moon Guang-Fu Cui Wei-Xin Qian Xiao-Jing Che Qian Zhang Shi-Shi Lai Ling Zhang Ying-Jie Zhu Jing-Dun Xie Tian-Wen Huang Shenzhen Key Laboratory of Drug Addiction Shenzhen-Hong Kong Institute of Brain ScienceBrain Cognition and Brain Disease InstituteShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong 518055China CAS Key Laboratory of Brain Connectome and Manipulation Brain Cognition and Brain Disease InstituteShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong 518055China University of Chinese Academy of Sciences Beijing 100049China Department of Anesthesiology State Key Laboratory of Oncology in South ChinaGuangdong Provincial Clinical Research Center for CancerSun Yat-sen University Cancer CenterGuangzhouGuangdong 510060China University of Science and Technology of China HefeiAnhui 230027China Department of Anesthesiology Shenzhen University General Hospital and Shenzhen University Academy of Clinical Medical SciencesShenzhen UniversityShenzhenGuangdong 518055China School of Medicine Yunnan UniversityKunmingYunnan 650091China

Painful stimuli elicit first-line reflexive defensive reactions and,in many cases,also evoke second-line recuperative behaviors,the latter of which reflects the sensing of tissue damage and the alleviation of *** lateral parabrachial nucleus(lPBN),composed of external-(elPBN),dorsal-(dlPBN),and central/superior-subnuclei(jointly referred to as slPBN),receives sensory inputs from spinal projection neurons and plays important roles in processing affective information from external threats and body integrity ***,the organizational rules of lPBN neurons that provoke diverse behaviors in response to different painful stimuli from cutaneous and deep tissues remain *** this study,we used region-specific neuronal depletion or silencing approaches combined with a battery of behavioral assays to show that slPBN neurons expressing substance P receptor(NK1R)(lPBNNK1R)are crucial for driving pain-associated self-care behaviors evoked by sustained noxious thermal and mechanical stimuli applied to skin or bone/muscle,while elPBN neurons are dispensable for driving such ***,lPBNNK1R neurons are specifically required for forming sustained somatic pain-induced negative teaching signals and aversive memory but are not necessary for fear-learning or escape behaviors elicited by external ***,both lPBNNK1R and elPBN neurons contribute to chemical irritant-induced nocifensive *** results reveal the functional organization of parabrachial substrates that drive distinct behavioral outcomes in response to sustained pain versus external danger under physiological conditions.

关键词： Lateral parabrachial nucleus Substance P receptor Pain affect Defensive reaction Somatosensory

Primary cutaneous follicular B cell lymphoma arised on the scalp

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Primary cutaneous follicular B cell lymphoma arised on the s...

Heavy metal chemistry in soils received long-term application of organic wastes

The Second Eastern Asia Dermatology Congress(EADC2012)

作者： Kyu Uang Whang Young Lip Jong Suk Park Jung Hoon Yoon Jee Lee Jung Eun seung Il Yang Ji Hoon hong Ki Kim Gang Mo Department of Dermatology Soonchunhyang University HospitalSeoulKorea

＜正＞Primary cutaneous follicular B cell lymphomas are rare entities of unknown cause,except for those induced by Epstein-Barr virus（EBV） or Borrelia *** has been thought rarely to occur primarily in the *** lesions are generally solitary plaques or nodules,localized on the head and *** shows considerable variation in clinical

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Journal of Agricultural Chemistry and Environment 2012年第1期1卷 1-9页

作者： Soon-Ik Kwon Yeon-Ah Jang Kye-Hoon Kim Goo-Bok Jung Min-Kyeong Kim Hae Hwang Mi-Jin Chae seung-Chang hong Kyu-Ho So Sun-Gang Yun Kwon-Rae Kim Gyeongnam National University of Science and Technology Jinju South Korea National Academy of Agricultural Science (NAAS) RDA Suwon South Korea The University of Seoul Seoul South Korea

This study was carried out to understand the long-term effect of organic waste treatment on the fate of heavy metals originated from the organic wastes, together with examination of changes in soil properties. For this, the soils received three different organic wastes (municipal sewage sludge, alcohol fermentation processing sludge, pig manure compost) in three different rates (12.5, 25, 50 ton/ha/yr) for 7 years (1994 - 2000) were used. To see the long-term effect, plant growth study and soil examination were conducted twice in 2000 and 2010, respectively. There was no additional treatment of organic wastes for post ten years after ceasing organic waste treatment for seven years. Soil examination conducted in 2010 showed decreases in soil pH, EC, total nitrogen, organic matter, available phosphorus, exchangeable cations and heavy metal contents in all soils received organic wastes compared to the results obtained in 2000. Speciation of heavy metals in soil through sequential extraction showed that organically bound Cu was the dominant species in all treatment and exchangeable Cu was increased in the plots treated with municipal sewage sludge and alcohol fermentation processing sludge. organically bound Ni increased from 25% - 30% to 32% - 45% in 2010 inall treatment while Pb showed increase in carbonate form in all treatments. Zn existed mainly as sulfide and residual forms, showing increases in organically bound form in all treatment during post ten years.

关键词： Heavy Metal Long-Term Application Organic Wastes Sequential Extraction