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Cancer stem cell markers CD133 and CD24 correlate with invasiveness and differentiation in colorectal adenocarcinoma

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World Journal of Gastroenterology 2009年第18期15卷 2258-2264页

作者： Dongho Choi Hyo Won Lee Kyung Yul Hur Jae Joon kim Gyeong-Sin Park Si-Hyong jang Young Soo Song ki-seok jang Seung Sam Paik Department of Surgery College of MedicineSoonchunhyang University140-743 SeoulSouth Korea Department of Surgery Chi Hang Hospital140-741 SeoulSouth Korea Department of Pathology College of MedicineCatholic University137-040 SeoulSouth Korea Department of Pathology College of MedicineHanyang University133-790 SeoulSouth Korea

AIM:To verify that CD markers are available for detecting cancer stem cell populations and to evaluate their clinical significance in colon ***:Immunohistochemistry for CD133,CD24 and CD44 was performed on the tissue microarray of 523 colorectal *** records were reviewed and clinicopathological analysis was ***:In colorectal adenocarcinoma,128 of 523 cases(24.5%) were positive and 395 cases(75.5%) were negative for CD133 *** hundred and sixty-four of 523 cases(50.5%) were positive and 259 cases(49.5%) were negative for CD24 *** hundred and two of 523 cases(96%) were negative and 21 cases(4%) were positive for CD44 *** clinicopathological analysis,CD133 expression was present more in male patients(P = 0.002) and in advanced T stage cancer(P = 0.024).Correlation between CD24 expression and clinicopathological factors was seen in the degree of differentiation(P = 0.006).Correlation between CD44 expression and clinicopathological factors was seen in the tumor size(P = 0.001).Survival was not significantly related to CD133,CD24 and CD44 ***:CD markers were related to invasiveness and differentiation of colorectal ***,CD expression was not closely related to survival.

关键词： CD133 CD24 CD44 Colon cancer stemcells Colorectal adenocarcinoma

Effects of precipitation strengthening heat treatment for Al-Mg alloy

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Transactions of Nonferrous Metals Society of China 2011年第6期21卷 1218-1224页

作者： Seong-Jong kiM seok-ki jang Min-Su HAN Seong-Kwon kiM Jong-Sin kiM Division of Marine System Engineering Mokpo Maritime University Mokpo City Jeonnam 530-729 Korea Media Engineering Seoul National University of Technology Seoul 139-743 Korea Korean Register of Shipping Tokyo Branch Office 3rd F Sanko BLDG＇ 4-11 Nohonbashi Kodenma-cho Cho-ku 103-0001 Tokyo Japan

The corrosions resulting from defects in painting layers frequently occur in Al alloys, so the application of corrosion preventing systems is also very important. Optimum conditions in terms of electrochemistry in relation to solution treatment, quenching and artificial aging treatment were established in order to optimize precipitation strengthening conditions intended to enhance the strength of Al alloys. Slow strain rate tests （SSRT） at various applied potentials were conducted in potential range from -1.8 to 0.5 V. The results show that the maximum tensile strengths, elongations and time-to-fracture are shown to be high values. After precipitation strengthening heat treatment, a tendency appear that time-to-fracture increases as elongation increases. In the potential range from -1.3 V to -0.7 V, the specimens show excellent mechanical properties, and thus this range is considered to be a corrosion prevention range.

关键词： Al alloy slow strain rate test electrochemistry precipitation strengthening heat treatment mechanical property

Cavitation and electrochemical characteristics of thermal spray coating with sealing material

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Transactions of Nonferrous Metals Society of China 2013年第4期23卷 1002-1010页

作者： Seong-Jong kiM Seung-Jun LEE In-Ju kiM Seong-Kweon kiM Min-Su HAN seok-ki jang Division of Marine Engineering Mokpo Maritime UniversityHaeyangdaehak-ro 91 Mokpo-Si530-729Korea Korea Institute of Industrial Technology 89 Yangdaegiro-gilIpjang-myeonSeobuk-guCheonan-Si331-822Korea Department of Electronic IT Media Engineering Seoul National University of Science & Technology138 Gongneung-gilNowon-gu Seoul139-743Korea

Steel applied in ocean environment is exposed to corrosion and cavitation and is subject to increasing damages. To prevent this, anti-corrosion thermal spray coating technique is widely used. The low-temperature thermal spray coating was performed with 85%Al-14.5%Zn-0.5%Zr for ship materials and various sealing materials were applied to improve its durability, and the electrochemical behavior and cavitation characteristics were observed. The results show that the sealing improves all the properties of the materials. Hybrid ceramic and fluoro-silicon sealing materials show good electrochemical characteristics, and the fluoro-silieon sealing material shows the best anti-cavitation characteristics.

关键词： thermal spray coating sealing material cavitation electrochemical characteristics

Mechanical and electrochemical characteristics in sea water of 5052-O aluminum alloy for ship

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Transactions of Nonferrous Metals Society of China 2013年第3期23卷 636-641页

作者： Seong-Jong kiM seok-ki jang Min-Su HAN Jae-Cheul PARK Jae-Yong JEONG Sang-Ok CHONG Division of Marine Engineering Mokpo Maritime Univers ityHaeyangdaehak-ro 91 Mokpo-Si530-729Korea

The optimum corrosion protection potentials were examined for 5052-O Al alloy,which is mainly used in *** electrochemical experiments were carried out and the surface morphologies of specimens were observed by scanning electron microscopy（SEM） in order to determine the optimum corrosion protection potential to overcome pitting,corrosion,stress corrosion cracking（SCC）,and hydrogen embrittlement in sea *** optimum protection potential range of-1.3 V to-0.7 V was determined under the application of an impressed current cathodic protection（ICCP） *** low current densities were shown in the range of-1.3 V to-0.7 V in the electrochemical experiments and good specimen surface morphologies were observed after potentiostatic experiment.

关键词： aluminum alloy corrosion electrochemical characteristics stress corrosion cracking hydrogen embrittlement sea water corrosion cathodic protection

Optimum traveling and rotation speeds in friction stir welding for dissimilar Al alloys

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Transactions of Nonferrous Metals Society of China 2011年第7期21卷 1486-1490页

作者： Jae-Cheul PARK Min-Su HAN seok-ki jang Seong-Jong kiM Division of Marine System Engineering Mokpo Maritime UniversityMokpo CityJeonnam530-729Korea

Aluminum alloys are subjected to large deformation and decreased strength due to the high expansion modulus caused by heat effects during friction stir welding （FSW）.The optimum conditions for friction stir welding of 5052-O and 6061-T6 Al alloys were *** optimum traveling and rotation speeds were identified to be 61mm/min and 1600r/min using various mechanical characteristic evaluation methods.

关键词： Al alloy friction stir welding (FSW) traveling speed rotation speed mechanical property

Self-supported VO_(2) on polydopamine-derived pyroprotein-based fibers for ultrastable and flexible aqueous zinc-ion batteries

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Carbon Energy 2024年第7期6卷 1-13页

作者： Jeong seok Yeon Sul ki Park Shinik kim Santosh VMohite Won Il kim Gun jang Hyun-seok jang Jiyoung Bae Sang Moon Lee Won GHong Byung Hoon kim Yeonho kim Ho seok Park School of Chemical Engineering College of EngineeringSungkyunkwan UniversityGyeonggi-doRepublic of Korea Department of Engineering University of CambridgeCambridgeUK Department of Applied Chemistry Konkuk UniversityChungjuRepublic of Korea Department of Chemistry Ulsan National Institute of Science and Technology(UNIST)College of Natural SciencesUlsanRepublic of Korea Department of Physics Incheon National UniversityIncheonRepublic of Korea Intelligent Sensor Convergence Research Center Incheon National UniversityIncheonRepublic of Korea Institute of Basic Science Incheon National UniversityIncheonRepublic of Korea Division of Material Analysis and Research Korea Basic Science InstituteDaejeonRepublic of Korea

A conventional electrode composite for rechargeable zinc-ion batteries(ZIBs)includes a binder for strong adhesion between the electrode material and the current ***,the introduction of a binder leads to electrochemical inactivity and low electrical conductivity,resulting in the decay of the capacity and a low rate *** present a binder-and conducting agent-free VO_(2) composite electrode using in situ polymerization of dopamine on a flexible current collector of pyroprotein-based *** as-fabricated composite electrode was used as a substrate for the direct growth of VO_(2) as a self-supported form on polydopamine-derived pyroprotein-based fibers(pp-fibers@VO_(2)(B)).It has a high conductivity and flexible nature as a current collector and moderate binding without conventional binders and conducting agents for the VO_(2)(B) *** addition,their electrochemical mechanism was *** energy storage is induced by Zn^(2+)/H^(+) coinsertion during discharging,which can be confirmed by the lattice expansion,the formation of by-products including Zn_(x)(OTf)_(y)(OH)_(2x−y)·nH_(2)O,and the reduction of V^(4+)to V^(3+).Furthermore,the assembled Zn//pp-fibers@VO_(2)(B) pouch cells have excellent flexibility and stable electrochemical performance under various bending states,showing application possibilities for portable and wearable power sources.

关键词： aqueous battery binder free conducting agent‐free flexible electrode zinc‐ion battery

DC Motor Speed Regulator via Active Damping Injection and Angular Acceleration Estimation Techniques

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IEEE/CAA Journal of Automatica Sinica 2021年第3期8卷 641-647页

作者： seok-Kyoon kim Choon ki Ahn Department of Creative Convergence Engineering Hanbat National UniversityDaejeon 341-58Republic of Korea School of Electrical Engineering Korea UniversitySeoul 136-701Republic of Korea

This paper suggests a novel model-based nonlinear DC motor speed regulator without the use of a current *** current dynamics,machine parameters and mismatched load variations are *** proposed controller is designed to include an active damping term that regulates the motor speed in accordance with the first-order low-pass filter dynamics through the pole-zero ***,the angular acceleration and its reference are obtained from simple first-order estimators using only the speed *** effectiveness is experimentally verified using hardware comprising the QUBEServo2,myRIO-1900,and LabVIEW.

关键词： Active damping injection angular acceleration estimator DC motor(DCM) speed regulation

Density functional theory study on the role of ternary alloying elements in TiFe-based hydrogen storage alloys

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Journal of Materials Science & Technology 2021年第33期92卷 148-158页

作者： Won-seok Ko ki Beom Park Hyung-ki Park School of Materials Science and Engineering University of UlsanUlsan 44610Republic of Korea Functional Materials and Components R&D Group Korea Institute of Industrial TechnologyGangneung 25440Republic of Korea

The role of additional ternary alloying elements on the performance of stationary TiFe-based hydrogen storage alloys was investigated based on first-principles density functional theory *** a basic step for examinations,the site preference of each alloying element in the stoichiometric and nonstoichiometric B2TiFe compounds was clarified considering possible antisite *** on the revealed site preference,the effect of various possible ternary elements on the hydrogen storage was examined by focusing on the formation enthalpies of TiFeH and TiFeH_(2) hydrides,which were closely related to the change in the location of plateaus in the pressure-composition-temperature *** physical properties such as the volume expansion due to hydride formation were also examined to provide additional criteria for selecting optimum alloying conditions in future alloying design *** alloying elements that maximize the grain boundary embrittlement due to the solute segregation were proposed for the enhanced initial activation of TiFe-based hydrogen storage alloys.

关键词： Hydrogen storage alloy Titanium-iron Density functional theory calculation Metallic hydride

Infrageneric relationships of Korean Viola based on eight chloroplast markers

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Journal of Systematics and Evolution 2010年第6期48卷 474-481页

作者： ki-Oug YOO Su-kil jang Department of Biological Sciences Kangwon National University

Phylogeny and infrageneric relationships were reconstructed for Korean Viola(Violaceae) using eight chloroplast sequences:the atpB-rbcL intergenic spacer,the atpF-H intergenic spacer,the matK gene,the psbA-trnH intergenic spacer,the psbK-I intergenic spacer,the rpl16 intron,the rpoC1 exon 2,and the trnL-trnF *** combined analyses of the eight chloroplast regions suggest that sections Dischidium and Chamaemelanium are monophyletic,whereas section Nomimium is paraphyletic;sections Dischidium and Chamaemelanium form a clade with subsections Hypocarpae and Trigonocarpae of section Nomimium,but unresolved within the clade;two subsections(*** and Vaginatae) of section Nomimium form a clade and are placed between the stem and stemless species group;and subsection Patellares of section Nomimium is monophyletic,and Viola dissecta is diverged first in the clade with high support(BS = 100,PP = 100).Our present results support the subsectional grouping based on morphological characteristics,although discordance remained at the series level.

关键词： chloroplast DNA infrageneric relationships phylogeny series subsection Viola.