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Asian Pacific Journal of Tropical Medicine 2012年第12期5卷 962-965页

作者： Khanavi Mahnaz Fallah Alireza Vatandoost Hassan sedaghat mahdi Abai Mohammad Reza Hadjiakhoondi Abbas Departments of Pharmacognosy Faculty of Pharmacy and Traditional Iranian Medicine and Pharmacy Research CenterTehran University of Medical SciencesTehranIran Department of Medical Entomology and Vector Control School of Public HealthTehran University of Medical SciencesTehranIran Departments of Pharmacognosy Faculty of Pharmacy and Medicinal Plants Research CenterTehran University of Medical SciencesTehranIran

Objective:To investigate the larvicidai activity of essential oil and methanol extract of the Nepeta menthoides（***） against main malaria vector,Anopheles stephensi（An. stephensi）.Methods:The essential oil of planl was obtained by Clevenger type apparatus and the methanol extract was supplied with Percolation method,larvicidai activity was tested by WHO *** five fourth-instar larvae of *** were used in the larvicidai assay and four replicates were tested for each *** different concentrations of the oil and extract were tested for calculation of LC50 and LC50 ***:The LC50 and LC90 values were determined by probit ***50 was 69.5 and 234.3 ppm and LC50 was 175.5 and 419.9 ppm for the extract and essential oil ***:According to the results of this study methanolic extract of plant exhibited more larvicidai activity than essential *** could be useful for investigation of new natural larvicidai compounds.

关键词： Larvicidal activity Anopheles stephensi Nepeta menthoides Methanol extract Essential oil

Er_(2)TiO_(5)@Ag nanocomposites:Enhanced photocatalysis and bacteria inactivation,and cytotoxicity

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Journal of Rare Earths 2024年第5期42卷 851-858,I0002页

作者： Mehdi Nazeri Hossein sedaghat Reza Rafiei Mohammad Amin Farzin Seyed Mostafa Hosseinpour Mashkani Department of Parasitology and Mycology Kashan University of Medical SciencesKashanIran Department of Microbiology Kashan University of Medical SciencesKashanIran General Medicine Student School of MedicineKashan University of Medical SciencesKashanIran Student Research Committee Kashan University of Medical SciencesKashanIran Institute for Biomedical Materials and Devices School of Mathematical and Physical SciencesFaculty of ScienceUniversity of Technology SydneyNSW2007Australia

In this study,we successfully synthesized Er_(2)TiO_(5)@Ag nanocomposites(NCPs) using the ultrasonicmediated sol-gel technique to create a multifunctional material with enhanced photocatalytic and antibacterial *** visible light photocatalytic activities of Er_(2)TiO_(5) nanoparticles(NPs) and Er_(2)TiO_(5)@Ag NCPs were systematically evaluated under various conditions,including different concentrations of Basic Blue 41(BB 41) dye and *** results reveal a remarkable improvement in the photocatalytic degradation efficiency of Er_(2)TiO_(5)@Ag NCPs(95%) compared to Er_(2)TiO_(5) NPs(80%).Furthermore,the antibacterial efficacy of Er_(2)TiO_(5) NPs and Er2TiO_5@Ag NCPs were extensively examined against Gram-positive and Gram-negative ***,Er_(2)TiO_(5)@Ag NCPs exhibit significantly higher minimum bactericidal concentration(MBC) values compared to Er_(2)TiO_(5) *** antibacterial effect of Er_(2)TiO_(5)@Ag NCPs is particularly pronounced against *** and Pseudomonas aeruginosa,while demonstrating moderate effects on Escherichia coli and Enterococcus *** assess the biocompatibility of the synthesized materials,we investigated their internalization by MCF-7 ***,both Er_(2)TiO_(5) NPs and Er_(2)TiO_(5)@Ag NCPs are found to be effectively internalized by the cells,suggesting their potential application in biomedical ***,our study unveils the exceptional potential of Er_(2)TiO_(5)@Ag NCPs as a dual-action solution,simultaneously possessing enhanced photocatalytic efficiency and potent antibacterial *** multifunctional nanocomposite not only outperforms Er_(2)TiO_(5) and Ag but also paves the way for innovative applications in sustainable environmental remediation and advanced biomedical technologies,promising a brighter and cleaner future.

关键词： Rare earth catalysis Nanocomposite Er_(2)TiO_(5)@Ag Antibacterial activity Photocatalysis Cytotoxicity

Modeling Expected Failure Considering Repair Time and Degradation: A Rail System Case Study

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Journal of Transportation Technologies 2024年第2期14卷 236-254页

作者： Maryam Hamidi Atefe sedaghat Amir Gharehgozli Ferenc Szidarovszky Department of Industrial and Systems Engineering Lamar University Beaumont TX USA Department of Systems and Operations Management California State University Northridge CA USA Department of Mathematics Corvinus University of Budapest F&#337v&#225mt&#233r 8 Budapest Hungary

The repeated failures of any equipment or systems are modeled as a renewal process. The management needs an assessment of the number of future failures to allocate the resources needed for fast repairs. Based on the idea of expectation by conditioning, special Volterra-type integral equations are derived for general types of repairs, considering the length of repair and reduced degradation of the idle object. In addition to minimal repair and failure replacement, partial repairs are also discussed when the repair results in reduction of the number of future failures or decreases the effective age of the object. Numerical integration-based algorithm and simulation study are performed to solve the resulting integral equation. Since the geometry degradation in different dimensions of a rail track and controlling and maintaining defects are of importance, a numerical example using the rail industry data is conducted. Expected number of failures of different failure type modes in rail track is calculated within a two-year interval. Results show that within a two-year period, anticipated occurrences of cross level failures, surface failures, and DPI failures are 2.4, 3.8, and 5.8, respectively.

关键词： Renewal Theory Expected Number of Failures Partial Repair Minimal Repair

Modeling Expected Failure Considering Repair Time and Degradation: A Rail System Case Study

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Synthesis,spectral studies,thermal behavior,and antibacterial activity of Ni(Ⅱ),Cu(Ⅱ),and Zn(Ⅱ) complexes with an ONO tridentate Schiff base

Journal of Transportation Technologies（交通科技期刊） 2024年第2期 236页

作者： Maryam Hamidi Atefe sedaghat Amir Gharehgozli Ferenc Szidarovszky

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Chinese Chemical Letters 2012年第9期23卷 1063-1066页

作者： Mohammad Azarkish Tahereh sedaghat Science & Research Branch Islamic Azad UniversityAhvazIran Department of Chemistry College ofSciencesShahid Chamran UniversityAhvazIran

Three new transition metal complexes have been synthesized with a Schiff base, 3-（2-hydroxy-5-chlorophenylimino）-1,3- diphenylpropen-l-one. In all complexes Schiff base is completely deprotonated and coordinated to metal as tridentate ligand via phenolic and enolic oxygens and imine nitrogen. Thermal decomposition of the complexes has been studied by thermogravimetry. The in vitro antibacterial activity of Schiff bases and their complexes has been evaluated and compared with the standard drugs.

关键词： Schiff base Transition metal Thermogravimetry Antibacterial activity

The impact of subcentimeter cysts on chronic scrotal pain

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Asian Journal of Andrology 2023年第6期25卷 750-752页

作者： Luca Rutigliani Pranjal Agrawal Amin sedaghat Herati School of Clinical Medicine The University of CambridgeCambridge CB20SPUK The James Buchanan Brady Urological Institute Johns Hopkins University School of MedicineBaltimoreMD 21224USA

Subcentimeter cysts can be the cause of severe chronic scrotal pain(CSP),a condition that significantly impacts patients and is often difficult to *** article aims to investigate the impact of subcentimeter cysts on CSP and compare the effectiveness of surgical removal for cysts of different *** primary outcome was the comparison of the average pain reduction pre-and *** a median postoperative time of 27.80(range:0.59–36.30)months,the average pain reduction was 6.00(standard deviation[s.d.]:2.27)for subcentimeter cysts and 2.72(s.d.:1.43)for larger cysts(P=0.0031).In total,81.0%of all patients were pain-free after cyst removal and 100.0%reported some improvement in *** postoperative pain reduction was significantly greater for subcentimeter cysts.

关键词： pain postoperative patients

Green bio-synthesis of Ni/montmorillonite nanocomposite using extract of Allium jesdianum as the nano-catalyst for electrocatalytic oxidation of methanol

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Chinese Journal of Chemical Engineering 2020年第10期28卷 2555-2565页

作者： Mohammad Hossein Sheikh-Mohseni Sajjad sedaghat Pirouz Derakhshi Aliakbar Safekordi Department of Chemistry Science and Research BranchIslamic Azad UniversityTehranIran Department of Chemistry Shahr-e-Qods BranchIslamic Azad UniversityShahr-e-QodsIran Department of Chemistry North Tehran BranchIslamic Azad UniversityTehranIran

In this work,synthesis of Ni nanoparticles was carried out successfully by water extract of Allium jesdianum as a biochemical reducing agent in the presence of montmorillonite clay(MMT)as a natural solid support for the first *** the electrochemical activity of the synthesized nanocomposite was investigated in methanol electrocatalytic *** with high cation exchange capacity and nano layer structure was exposed to ion exchange conditions in nickel *** Ni^2+ion exchanged form was used in this process as a source of ions and also capping *** extract of Allium jesdianum used as a reducing agent due to abundant availability of phenolic and flavonoid *** synthesized Ni/MMT nanocomposite was characterized using UV–Vis spectroscopy(UV–Vis),Fourier Transform Infrared Spectroscopy(FT-IR),X-ray diffraction(XRD),Scanning Electron Microscopy(SEM),Transmission electron microscopy(TEM)and Energy-dispersive X-ray spectroscopy(EDX).The surface of prepared modified electrode has been characterized using SEM to evaluate the morphology,showing uniform dispersion of Ni nanoparticles with mean diameter of 12 to 20 *** modified carbon paste electrode was then used in methanol electrocatalytic oxidation *** oxidation on the proposed modified electrode surface occurs at 0.6 V and 0.3 V in alkaline and acidic medium ***,the results showed the better performance of modified electrode toward methanol electrocatalytic oxidation in comparison with carbon paste electrode that is modified by ion exchanged *** transfer coefficients and apparent charge transfer rate constant for the modified electrode in the absence of methanol in alkaline medium were respectively found as:αa=0.53,αc=0.37 and ks=1.6×10^-1 s^-***,the average value of catalytic rate constant for the electrocatalytic oxidation of methanol by the prepared nano-catalyst was estimated to be about 0.9 L·mol^-1·s^-1 by chronoamperometry *** prepare

关键词： Green biosynthesis Nanoparticles Montmorillonite Biocatalysis Methanol electrocatalytic oxidation Fuel cell

A comparative study of stress influence on fracture apertures in fragmented rocks

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Journal of Rock Mechanics and Geotechnical Engineering 2019年第1期11卷 38-45页

作者： Hossein Agheshlui Mohammad H.sedaghat Siroos Azizmohammadi Department of Infrastructure Engineering The University of Melbourne Centre for Coal Seam Cas The University of Queensland Department of Petroleum Engineering Montanuniversitat Leoben

This study compares the calculated fracture apertures in a fragmented rock layer under different stress scenarios using two different approaches. Approach 1 is a simplified method using a two-dimensional(2 D) mapping of the fracture network and projects the far-field stresses to individual fractures, and calculates the dilation, normal and shear displacements using experimental stiffnesses available in the literature. Approach 2 employs a three-dimensional(3 D) finite element method(FEM) for the mechanical analysis of the fragmented rock layer considering the interaction with the neighbouring rock layers, frictional interfaces between the rock blocks, stress variations within the fragmented rock layer,and displacements, rotations and deformations of rock blocks. After calculating the fracture apertures using either of the approaches, the permeability of the fragmented rock layer is calculated by running flow simulations using the updated fracture apertures. The comparison between the results demonstrates an example of the inaccuracies that may exist in methods that use simplified assumptions such as2 D modelling, ignoring the block rotations and displacements, projected far-field stresses on fractures,and the stress variations within the rock layer. It is found that for the cases considered here, the permeability results based on apertures obtained from the simplified approach could be 40 times different from the results from apertures calculated using a full mechanical approach. Hence, 3 D mechanical modelling implementing realistic boundary conditions, while considering the displacements and rotations of rock blocks, is suggested for the calculation of apertures in fragmented rocks.

关键词： Fracture aperture change In situ stresses Frictional interfaces Ensemble permeability

Synthesis, Characterization, Spectroscopy and Study of Antimicrobial Properties of Two New Substituted Trichloroaluminate(Ⅲ) Complexes [AlCl_3X]^- (X = SCN^-, CN^-)

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Chinese Journal of Structural Chemistry 2013年第1期32卷 67-72页

作者： Zahra Shokri Aghbolagh Shahriar Ghammamy Sajjad sedaghat Shahram Jahandide Young Research Club Takestan Branch Islamic Azad University Takestan Iran Department of Chemistry Faculty of Science Islamic Azad University Malard Branch Malard Iran Department of Chemistry Faculty of Science Islamic Azad University Ardabil Branch Ardabil Iran

The synthesis and characterization of two new aluminate（Ⅲ） complexes with general formula K[AlCl3X] are reported. These compounds derived from aluminate trichloride and related salts. Potassium trichlorothiocyanoaluminate, PCTA, and potassium trichlorocyanatoalu-minate, PCCA, are two new ionic aluminate complexes. They can be easily synthesized in a nearly quantitative yield by using the direct reaction of AlCl3 and KX. The complexes were characterized by physico-chemical and spectroscopic methods. Theoretical calculations have been used for the extraction of structural and spectroscopic data of these new synthesized complexes. The antibacterial activities of such compounds were studied against the Staphylococcus aureus, Escherichia coli, Staphylococcus Epidermidis, Estreptococo B and Shigella.

关键词： aluminate compounds synthesis characterization PCTA PCCA theoretical calculation antibacterial activities

Molecular characterization of sandflies and Leishmania detection in main vector of zoonotic cutaneous leishmaniasis in Abarkouh district of Yazd province,Iran

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Asian Pacific Journal of Tropical Medicine 2013年第10期6卷 792-797页

作者： Jafari R Najafzadeh N sedaghat MM Parvizi P National Institute of Health Research Isfahan Health Research Station Molecular Systematic Laboratory Parasitology DepartmentPasteur Institute of Iran Department of Microbiology Islamic Azad UniversityScience and Research Branch of Fars Department of Medical Entomology and Vector Control School of Public HealthTehran University of Medical Sciences

Ohjective:To assess molecular characterization,distribution,seasonal activities of sandfly species and Leishmania parasites infecting them for this zoonotic cutaneous leishmaniasis ***:The collections were carried out in 2009-2011 using CDC traps,Sticky Papers and manual aspirator in and around the villages in Abarkouh *** sandflies were characterized by PCR amplification and sequencing of fragments of their mitochondrial cytochrome b *** parasite infections within sandflies were performed by targeting Cyt b,ITS-rDNA,k-DNA and microsatellite ***:The PCR assays detected only Leishmania major(***).All infections(30)were found in the abundant and widespread vector Phlebolomus papalasi(***).Small numbers of other sandfly species were also screened for infections,but none was *** sinloni and *** were the predominant members in all locations of this district and in all habitats throughout the trapping *** five other sandfly species were found,namely Phlebolomus ansari,Phlebotomus caucasicus,Phlebotomus sergenti,Sergentomyia dentata and Sergentomyia ***:In the current survey,the only infections detected are of *** in females of ***(30 out of190).The rates of infection of *** by *** are not significantly different in compare with other locations in Iran with no diversity of parasite *** cutaneous leishmaniasis may have emerged only recently in Abarkouh district,and the reason may well be the instability of the transmission cycles there.

关键词： Zoonotic cutaneous leishmaniasis Phlebotomus papatasi Leishmania major Sandfly Central Iran