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Assessment of albendazole efficacy against Ascaris lumbricoides at three sites of Andhra Pradesh,Odisha,and Kerala in India

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Asian Pacific Journal of Tropical Medicine 2024年第7期17卷 310-316页

作者： Vinay Garg Ankur Garg Shubha Garg Sudhir Kumar jain Tanzin Dikid saurabh jain Jitendra Manjhi Antonio Montresor Atul Goel Division of Parasitic Diseases National Centre for Disease ControlMinistry of Health and Family WelfareGovernment of India22-Sham Nath MargCivil LinesNew Delhi-110054India National Centre for Disease Control Ministry of Health and Family WelfareGovernment of India22-Sham Nath MargCivil LinesNew Delhi-110054India Epidemiology Division National Centre for Disease ControlMinistry of Health and Family WelfareGovernment of India22-Sham Nath MargCivil LinesNew Delhi-110054India Department of Control of Neglected Tropical Diseases(NTD) World Health Organization(WHO)Av Appia 20 CH-1211Geneva 27Switzerland Department of Community&Family Medicine AIIMS KalyaniIndia Community and Primary Care-based Intervention Department of Control of Neglected Tropical Diseases(NTD)World Health Organization(WHO)Av Appia 20 CH-1211Geneva 27Switzerland Director General of Health Sciences(DGHS)&Director National Centre for Disease ControlMinistry of Health and Family WelfareGovernment of India22-Sham Nath MargCivil LinesNew Delhi-110054India

Objective:To assess efficacy of albendazole against Ascaris(A.)lumbricoides among school-children at three sites of Rajahmundry,Sundergarh and ***:Sites were selected based on soil-transmitted helminths prevalence,different sociocultural-geographical characteristics and operational feasibility.9-12 Years old children from 14 schools were *** study was conducted in two rounds:baseline&follow up *** eligible children found positive for *** at baseline were administered supervised single tablet albendazole 400 mg under the National Deworming Day *** post-treatment follow-up survey,eligible children who provided second stool sample were included in the final *** samples were examined using WHO recommended Kato-Katz *** was estimated based on cure rate(CR)and Fecal Egg Count Reduction Rate(FECRR)among children found positive in baseline and follow-up ***:328 Out of 625(52.5%)were found positive for *** in the baseline survey and 85 out of 178 samples(47.8%)during post-treatment follow-up ***,the estimated CR was 52.2%.FECRR(95%CI)for albendazole was 72.6%(79.2%-66.0%).The FECRR was highest in East Godaveri[89.7%(96.8%-82.6%)],followed by Sundergarh[86.4%(95.3%-77.5%)]and Wayanad[69%(81.7%-56.4%)].Conclusions:Our study confirmed overall reduction in FEC although with varying albendazole efficacy for *** infection at three different locations in ***,these finding may be assessed in context of ongoing MDA under Filaria control program and further studies by in vivo as well as in vitro methods are required to reach to a conclusion on possible resistance if any.

关键词： Soil transmitted helminths Ascaris lumbricoides Albendazole Efficacy

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Outcome of open reduction and internal fixation of intraarticular calcaneal fracture fixed with locking cal- caneal plate

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Chinese Journal of Traumatology 2013年第6期16卷 355-360页

作者： saurabh jain Anti Kumar jain Ish Kumar Department of Orthopaedics Mahaveer HospitalIndore India Department of Orthopaedics UCMS and GTB HospitalDelhi India

Objective：Debate continues regarding the management of calcaneal fractures,between open reduction and internal fixation and closed *** we aim at evaluating the radiological and functional outcomes of open reduction and internal fixation in displaced joint depression type of calcaneal fractures fixed with locking calcaneal ***：In this series,28 patients （26 unilateral and 2 bilateral） with joint depression type of calcaneal fractures as per Essex-Lopresti classification system were operated on with locking calcaneal plate within 3 weeks of *** were evaluated in terms of associated injuries and X-rays of anteroposterior,lateral and axial views of the *** scan was done to assess the amount ofcomminution and articular *** were followed up clinically and radiologically at least for 1 *** assessment was done by Bohler＇s angle and Gissane＇s angle along with measurement ofcalcaneal height and *** outcome was assessed using the American Orthopaedics Foot and Ankle Society （AOFAS） ***：At average follow-up of 14.5 months,average AOFAS score was 86.3 （range 66 to 97）,with 86% having excellent to good results and 2 （7.7%） and 1 （3.7%） having fair and poor results *** patients had stable ankle joint with all having dorsiflexion and plantar flexion more than 30°.Average subtalar range of motion was 17°.The mean Bohler＇s angle,mean Gissane＇s angle,calcaneal height and width were 25.47°,121.3°,4.32 cm and 3.81cm respectively at final *** patients had flap necrosis at incision site and one had superficial and deep *** arthritis was seen in 5 patients,whereas sural nerve hypoaesthesia in 1 *** of the patients had compartment syndrome,heel pad problems,peroneal tendinitis,reflex sympathetic dystropy or implant ***：Open reduction and internal fixation with locking calcaneal plate gives sound functional outcome,*** anato

关键词： Calcaneus Fractures, bone Boneplates Fracture f'ocation, internal

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Retrieval of a broken guide wire transfixing the hip through the proximal femoral nail hole

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Chinese Journal of Traumatology 2014年第1期17卷 50-53页

作者： saurabh jain Abhishek Pathak Rajeev Kant Pandey Department of Orthopaedics Gandhi Medical College Bhopal India

Retrieval of a broken guide wire transfix- ing the acetabulum or with intrapelvic migration is challeng- ing and frustrating for surgeons. We here present a case report on a method to remove a broken guide wire transfix- ing the acetabulum through the proximal hole of recon nail using a grasping forceps. This method is little invasive,easy, time-saving and without need for changing the inital fixation.

关键词： Hip fractures Complications Instru-mentation

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Outcome of buttress plate-nail construct used for reconstruction of broken lateral wall in intertrochanteric fractures

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Chinese Journal of Traumatology 2023年第4期26卷 223-227页

作者： saurabh jain Satish Rohra Harshwardhan Dawar Bhupendra Kushwah Adit Agrawa Department of Orthopaedics MGM Medical College and MY HospitalIndoreMadhya Pradesh452009India

Purpose:Intramedullary implants are well accepted fixation of all types of intertrochanteric(IT)frac-tures,both stable and unstable *** nails have an ability to effectively support the posteromedial part,but fail to buttress the broken lateral wall requiring lateral *** aim of this study was to evaluate the outcome of proximal femoral nail augmented with trochanteric buttress plate for broken lateral wall with IT fractures,which was fixed to the femur through hip screw and anti-rotation screw ***:Of 30 patients,20 had Jensen-Evan typeⅢand 10 had type V *** with IT fracture of broken lateral wall and aged more than 18 years,in whom satisfactory reduction was achieved by closed methods,were included in the *** with pathologic or open fractures,polytrauma,prior hip surgery,non-ambulatory prior to surgery,and those who refused to participate were *** operative time,blood loss,radiation exposure,quality of reduction,functional outcome,and union time were *** data were coded and recorded in Microsoft Excel spread sheet *** 20.0 was used for data analysis and normality of the continuous data was checked using Kolmogorv Smirnov ***:The mean age of patients in the study was 60.3 *** mean duration of surgery(min),mean intra-operative blood loss(mL)and mean number of exposures were 91.86±12.8(range 70-122),144.8±3.6(range 116-208),and 56.6(range 38-112),*** mean union time was 11.6 weeks and the mean Harris hip score was ***:Lateral trochanteric wall in IT fractures is significantly important,and needs to be recon-structed ***-plate construct of trochanteric buttress plate fixed with hip screw and anti-rotation screw of proximal femoral nail can be successfully used to augment,fix or buttress the lateral trochanteric wall giving excellent to good results of early union and reduction.

关键词： Intertrochanteric fracture Lateral trochanteric wall Intramedullary nail Proximal femoral nail Trochanteric buttress plate

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Neglected isolated fracture of the trochlea humeri

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Chinese Journal of Traumatology 2010年第4期13卷 247-249页

作者： Ajay Pal Singh Ish Kumar Dhammi Anil Kumar jain saurabh jain Department of Orthopaedics Guru Teg Bahadur Hospital University College of Medical Sciences University of Delhi Delhi 110095 India

A 15 years old girl was found to have isolated trochlea fracture 10 weeks after an injury caused by a fall on her left elbow. Movement of the elbow was severely restricted. Radiographs showed a half moon-shaped and anterosuperiorly displaced osteochondral fragment. Medial approach capsulotomy of the elbow and excision of the intraarticular adhesions were done to expose the isolated trochlea fracture. Headless screws were used for fixation, combined with bone grafting. The follow-up showed union and excellent functional recovery of the elbow. Isolated trochlea fracture in adults is rare and usually associated with capitellar fractures and/or elbow dislocations. A neglected trochlea fracture is rarely reported in the English language literature to the best of our knowledge. Recognition of isolated trochlea fracture is vital to apprehend the pathomechanics of the injury and to devise a suitable treatment approach.

关键词： Fractures, bone Humerus Elbow

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An experimental study on optimizing parameters for sand consolidation with organic-inorganic silicate solutions

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Petroleum 2024年第3期10卷 483-493页

作者： saurabh Mishra Geetanjali Chauhan Keka Ojha Department of Energy Science and Technology Centre for Advanced StudiesLucknowIndia Department of Petroleum Engineering and Earth Sciences Indian Institute of Petroleum and EnergyVisakhapatnamIndia Department of Petroleum Engineering Indian Institute of Technology(ISM)DhanbadIndia

Sand production along with the oil/gas detrimentally affects the oil production rate,downhole&subsurface *** equipment and various chemicals like epoxy resin,furan resin,phenolic resin,*** used in the industry to reduce or eliminate this *** the present study,a blend of organic and inorganic silicates are used to consolidate loose sand in the presence and absence of crude oil using a core flooding *** effects of chemical concentration,pH,curing temperature and time,and the presence of residual oil on the consolidation treatment results such as compressive strength and permeability retention,were investigated and ***-IR and FE-SEM characterization techniques were employed to investigate the interaction between the chemical molecules and the sand *** current binding agent exhibited a viscosity of less than 6 cP at room temperature,which facilitates efficient pumping of binding agent into the desired formation through the well *** developed mixture demonstrated consolidation properties across all pH ***,during the experimental investigation,the curing time and temperature was carefully optimized at 12 h and 423.15K,respectively to achieve the highest compressive strength of 2021 psi while achieving the permeability retention of 64%.The current chemical system exhibited improved consolidation capacity and can be effectively utilized for sand consolidation treatment in high-temperature formations.

关键词： Chemical sand consolidation Rheology Compressive strength Permeability retention Silicate system Curing

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EPASAD:ellipsoid decision boundary based Process-Aware Stealthy Attack Detector

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Cybersecurity 2024年第3期7卷 32-48页

作者： Vikas Maurya Rachit Agarwal saurabh Kumar Sandeep Shukla Department of Computer Science and Engineering Indian Institute of Technology KanpurkanpurIndia Merkle Science BangaloreIndia

Due to the importance of Critical Infrastructure(Cl)in a nation's economy,they have been lucrative targets for cyber *** critical infrastructures are usually Cyber-Physical Systems such as power grids,water,and sewage treatment facilities,oil and gas pipelines,*** recent times,these systems have suffered from cyber attacks numer-ous *** have been developing cyber security solutions for Cls to avoid lasting *** to standard frameworks,cyber security based on identification,protection,detection,response,and recovery are at the core of these *** of an ongoing attack that escapes standard protection such as firewall,anti-virus,and host/network intrusion detection has gained importance as such attacks eventually affect the physical dynamics of the ***,anomaly detection in physical dynamics proves an effective means to implement *** is one example of anomaly detection in the sensor/actuator data,representing such systems physical *** present EPASAD,which improves the detection technique used in PASAD to detect these micro-stealthy attacks,as our experiments show that PASAD's spherical boundary-based detection fails to *** method EPASAD overcomes this by using Ellipsoid boundaries,thereby tightening the boundaries in various dimen-sions,whereas a spherical boundary treats all dimensions *** validate EPASAD using the dataset produced by the TE-process simulator and the C-town *** results show that EPASAD improves PASAD's average recall by 5.8%and 9.5%for the two datasets,respectively.

关键词： Intrusion detection system Critical infrastructure security Industrial control system Machine learning

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A hybrid machine learning approach based study of production forecasting and factors influencing the multiphase flow through surface chokes

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Petroleum 2024年第2期10卷 354-371页

作者： Waquar Kaleem saurabh Tewari Mrigya Fogat Dmitriy A.Martyushev Department of Industrial and Manufacturing Engineering The Pennsylvania State UniversityUniversity ParkPA16802United States Department of Data Sciences Gyan Ganga Institute of Technology and SciencesJabalpur482002India Department of Petroleum and Geo-Engineering Rajiv Gandhi Institute of Petroleum Technology JaisBahadurpur229304India Department of Oil and Gas Technologies Perm National Research Polytechnic UniversityPerm614990Russia

Surface chokes are widely utilized equipment installed on wellheads to control hydrocarbon flow *** correlations have been suggested to model the multiphase flow of oil and gas via surface ***,substantial errors have been reported in empirical fitting models and correlations to estimate hydrocarbon flow because of the reservoir's heterogeneity,anisotropism,variance in reservoir fluid characteristics at diverse subsurface depths,which introduces complexity in production ***,the estimation of daily oil and gas production rates is still challenging for the petroleum ***,hybrid data-driven techniques have been reported to be effective for estimation problems in various aspects of the petroleum *** paper investigates hybrid ensemble data-driven approaches to forecast multiphase flow rates through the surface choke(*** generalization and voting architectures),followed by an assessment of the impact of input production control ***,machine learning models are also trained and tested individually on the production data of hydrocarbon wells located in North *** engineering has been properly applied to select the most suitable contributing control variables for daily production rate *** study provides a chronological explanation of the data analytics required for the interpretation of production *** test results reveal the estimation performance of the stacked generalization architecture has outperformed other significant paradigms considered for production forecasting.

关键词： Machine learning Tree-based methods Stacking ensemble Multiphase flow Data analytics Wellhead choke variables

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Barriers and drivers for sustainable public transportation in Indian context

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Green Energy and Intelligent Transportation 2024年第1期3卷 32-45页

作者： Gopi R Dev Vrat Pathak saurabh Pratap Lakshay Department of Mechanical Engineering Indian Institute of TechnologyVaranasiIndia

Rising negative externalities,including greenhouse gas emissions,climate change,and environmental pollution,shows the need for sustainable and environmentally friendly modes of *** zero-emission,environmentally friendly electric buses in public transportation systems can be an effective solution for both developing and developed countries,including *** the Indian government is making numerous efforts to promote electric buses in commercial and public transportation systems,it faces several formidable *** research objective is to analyze and evaluate the primary factors influencing the adoption and usage of electric buses in the Indian public transportation system,within the limited available resources.A survey questionnaire is prepared with several perceptual subjects for the key perceived *** empirical analysis using Structural Equation Modeling(SEM)is then performed to identify the critical *** result of this study demonstrates that the infrastructural barriers substantially impact the adoption and utilization of electric ***,the study provides critical insights and managerial implications for decision-makers.

关键词： Electric bus adoption Public transportation system Barriers Structural equation modelling Exploratory factor analysis Confirmatory factor analysis

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Role of endoscopic ultrasound-guided biliary drainage for palliation of malignant biliary obstruction

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2369-2373页

作者： Sahib Singh saurabh Chandan Antonio Facciorusso Department of Internal Medicine Sinai HospitalBaltimoreMD 21215United States Center for Interventional Endoscopy(CIE) Advent HealthOrlandoFL 32803United States Gastroenterology Unit Department of Medical and Surgical SciencesUniversity of FoggiaFoggia 71122Italy

Endoscopic ultrasound-guided biliary drainage(EUS-BD)directs bile flow into the digestive tract and has been mostly used in patients with malignant biliary obstruction(MBO)where endoscopic retrograde cholangiopancreatography-guided biliary drainage was unsuccessful or was not *** apposing metal stents(LAMS)are deployed during EUS-BD,with the newer electrocautery-enhanced LAMS reducing procedure time and complication rates due to the inbuilt cautery at the catheter ***-BD with electrocautery-enhanced LAMS has high technical and clinical success rates for palliation of MBO,with bleeding,cholangitis,and stent occlusion being the most common adverse *** studies have even suggested comparable efficacy between EUS-BD and endosc-opic retrograde cholangiopancreatography as the primary approach for distal *** this editorial,we commented on the article by Peng et al published in the recent issue of the World Journal of Gastrointestinal Surgery in 2024.

关键词： Endoscopic ultrasound Endoscopic ultrasound guided biliary drainage Cancer Pancreas Bile duct Endoscopy

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