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Invasive group B streptococcal infection in a patient with post splenectomy for hypersplenism secondary to liver cirrhosis and portal hypertension

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World Journal of Emergency Medicine 2016年第1期7卷 68-70页

作者： Tomoya Okazaki Toru Hifumi Arisa Manabe Hikari Matsumura satoshi egawa Hideyuki Hamaya Nastuyo Shinohara Koshiro Takano Hajime Shishido Yuko Abe Kenya Kawakita Masanobu Hagiike Yasuhiro Kuroda Emergency Medical Center Kagawa University Hospital Kita Kagawa 761-0793 Japan

BACKGROUND:Splenectomy in patients with liver cirrhosis(LC)is expected to become more common owing to its efficacy on portal *** this report we describe an alarming case of group B streptococcus(GBS)infection after splenectomy in a patient with ***:A 72-year-old woman with a history of LC was admitted to our emergency department because of respiratory *** patient had received left lateral segmentectomy of the liver and splenectomy three months before *** examination revealed significant wheezing during inspiration and expiration,but no crackles and *** radiography and CT showed no infiltrates.A presumptive diagnosis of bronchial asthma caused by upper respiratory infection was *** days after admission,GBS infection was confirmed by blood culture and penicillin G was *** were given intravenously for a total of 12 ***:The patient was discharged on the 12th day after ***:Although efficacy of splenectomy in patients with LC has been reported,immune status should be evaluated for a longer *** who have undergone splenectomy are highly susceptible to bacteria;moreover,LC itself is an independent risk factor for mortality in patients with *** prophylaxis against GBS has not been established,immediate action should be *** physicians should be aware of invasive GBS infection in the context of the critical risk factors related to splenectomy and LC,particularly the expected increase of splenectomy performed in LC patients.

关键词： Group B streptococcal infection Splenectomy Liver cirrhosis

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Comparative study of esomeprazole and lansoprazole in triple therapy for eradication of Helicobacter pylori in Japan

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World Journal of Gastroenterology 2014年第15期20卷 4362-4369页

作者： Tsutomu Nishida Masahiko Tsujii Hirohisa Tanimura Shusaku Tsutsui Shingo Tsuji Akira Takeda Atsuo Inoue Hiroyuki Fukui Toshiyuki Yoshio Osamu Kishida Hiroyuki Ogawa Masahide Oshita Ichizo Kobayashi Shinichiro Zushi Makoto Ichiba Naoto Uenoyama Yuichi Yasunaga Ryu Ishihara Mamoru Yura Masato Komori satoshi egawa Hideki Iijima Tetsuo Takehara Department of Gastroenterology and Hepatology Osaka University Graduate School of MedicineSuitaOsaka 565-0871Japan Department of Gastroenterology Osaka Kaisei HospitalOsaka 532-0003Japan Department of Gastroenterology Itami City HospitalItami 664-8540Japan Department of Gastroenterology Osaka Seamen’s Insurance HospitalOsaka 552-0021Japan Department of Gastroenterology Ashiya Municipal HospitalAshiya 659-8502Japan Department of Gastroenterology Osaka General Medical CenterOsaka 558-8558Japan Department of Gastroenterology Yao Municipal HospitalYao 581-0069Japan Department of Gastroenterology Osaka National HospitalOsaka 540-0006Japan Department of Gastroenterology Sumitomo HospitalOsaka 565-0871Japan Department of Gastroenterology Nishinomiya Municipal Central HospitalNishinomiya 663-8014Japan Department of Internal Medicine Osaka Police HospitalOsaka 543-0035Japan Department of Gastroenterology Higashiosaka City General HospitalHigashiosaka 578- 8588Japan Department of Gastroenterology Ikeda Municipal HospitalIkeda 563-0025Japan Department of Gastroenterology Toyonaka Municipal HospitalToyonaka 560-0055Japan Department of Gastroenterology Otemae HospitalOsaka 540-0008Japan Department of Gastroenterology Hyogo Prefectural Nishinomiya HospitalNishinomiya 662-0918Japan Department of Gastrointestinal Oncology Osaka Medical Center for Cancer and Cardiovascular DiseaseOsaka 537-0025Japan Department of Gastroenterology Minoh City HospitalMinoh 562-0014Japan Department of Gastroenterology Osaka Rosai HospitalSakai 591-8025Japan Department of Gastroenterology Kansai Rosai HospitalAmagasaki 660-8511Japan

AIM: To evaluate the efficacy and safety of esomeprazole-based triple therapy compared with lansoprazole therapy as first-line eradication therapy for patients with Helicobacter pylori (H. pylori) in usual post-market... 详细信息

关键词： Helicobacter pylori Eradication Esomeprazole Lansoprazole Proton pomp inhibitor

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Coptidis Rhizoma Water Extract Stimulates 5'-AMP-Activated Protein Kinase in Rat Skeletal Muscle

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中国天然药物 2011年第3期9卷 215-221页

作者： Tatsuro egawa Rieko Oshima Eriko Kurogi Hiroko Tanabe satoshi Tsuda Tatsuya Hayashi Laboratory of Sports and Exercise Medicine Graduate School of Human and Environmental StudiesKyoto University

AIM:Coptidis Rhizoma(CR),the dried rhizomes of Asian herbs(including Coptis chinensis Franch),has been used to treat diabetes mellitus for thousands of *** explored the possibility that CR acts directly on skeletal muscle,the major organ responsible for glucose homeostasis,and activates 5'-AMP-activated protein kinase(AMPK),a signaling intermediary leading to metabolic enhancement of skeletal ***:Isolated rat epitrochlearis and soleus muscles were incubated in a buffer containing a CR water extract(CE),and activation of AMPK and related events were ***:In response to CE treat-ment,phosphorylation of Thr172 at the catalyticαsubunit of AMPK,an essential step for full kinase activation,increased in both *** of Ser79 of acetyl CoA carboxylase(ACC),an endogenous substrate of AMPK,increased *** of isoform-specific AMPK activity revealed that CE activated both the α1 and α2 isoforms of the catalytic ***,the maximal effect of CE on AMPK phosphorylation was significantly greater than that of berberine(BBR),indicating that the action of CE is not totally ascribed to ***:We propose that CE is an acute activator of AMPK in both fast-and slow-twitch skeletal muscles.

关键词： Coptidis Rhizoma Coptis chinensis 5’-AMP-activated protein kinase Skeletal muscle Berberine

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