检索结果-南通市图书馆

Approximate any 1-state solutions of the Dirac equation for modified deformed hylleraas potential by using the Nikiforov—Uvarov method

在线全文

学校读者我要写书评

暂无评论

Chinese Physics B 2012年第12期21卷 57-65页

作者： h.hassanabadi e.Maghsoodi S.Zarrinkamar h.Rahimov Physics Department Shahrood University of TechnologyShahroodIran Department of Basic Sciences Garmsar BranchIslamic Azad UniversityGarmsarIran Computer engineering Department Shahrood University of TechnologyShahroodIran

We investigate the spin and pseudospin symmetries of the Dirac equation under modified deformed hylleraas potential via a Pekeris approximation and the Nikiforov-Uvarov technique. A tensor interaction of Coulomb form is considered and its degeneracy-removing role is discussed in detail. The solutions are reported for an arbitrary quantum number in a compact form and useful numerical data are included.

关键词： Dirac equation spin symmetry pseudospin symmetry modified hylleraas potential

Lymphocyte phenotypes in wild-caught rats suggest potential mechanisms underlying increased immune sensitivity in post-industrial environments

在线全文

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2012年第2期9卷 163-174页

作者： Ashley M Trama Zoie e holzknecht Anitra D Thomas Kuei-Ying Su Sean M Lee emily e Foltz sarah e Perkins Shu S Lin William Parker Department of Surgery Duke University Medical Center Durham NC 27710 USA Cardiff School of Biosciences Cardiff CFIO 3AX UK Department of Immunology Duke University Medical Center Durham NC 27710 USA

The immune systems of wild rats and of laboratory rats can been utilized as models of the human immune system in pre-industrial and post-industrial societies, respectively. In this study, lymphocyte phenotypes in wild rats were broadly characterized, and the results were compared to those obtained by us and by others using cells derived from various strains of laboratory rats. Although not expected, the production of regulatory T cells was not apparently different in wild rats compared to laboratory rats. On the other hand, differences in expression of markers involved in complement regulation, adhesion, signaling and maturation suggest increased complement regulation and decreased sensitivity in wild-caught rats compared to laboratory rats, and point toward complex differences between the maturation of T cells. The results potentially lend insight into the pathogenesis of post-industrial epidemics of allergy and autoimmune disease.

关键词： allergy autoimmunity biome hygiene immune regulation

TRPC3 is required for the survival, pluripotency and neural differentiation of mouse embryonic stem cells(meSCs)

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Life Sciences) 2018年第3期61卷 253-265页

作者： helen Baixia hao sarah e. Webb Jianbo Yue Marc Moreau Catherine Leclerc Andrew L. Miller Division of Life Science and State Key Laboratory of Molecular Neuroscience HKUST Clear Water Bay Hong Kong China Department of Biomedical Sciences City University of Hong Kong Hong Kong China Centre de Biologie du Développement (CBD) Centre de Biologie Intégrative (CBI) Université de Toulouse CNRS UPS Toulouse F-31062 France

Transient receptor potential canonical subfamily member 3(TRPC3) is known to be important for neural development and the formation of neuronal networks. here, we investigated the role of TRPC3 in undifferentiated mouse embryonic stem cells(meSCs) and during the differentiation of meSCs into neurons. CRISPR/Cas9-mediated knockout(KO) of TRPC3 induced apoptosis and the disruption of mitochondrial membrane potential both in undifferentiated meSCs and in those undergoing neural differentiation. In addition, TRPC3 KO impaired the pluripotency of meSCs. TRPC3 KO also dramatically repressed the neural differentiation of meSCs by inhibiting the expression of markers for neural progenitors, neurons, astrocytes and *** together, our new data demonstrate an important function of TRPC3 with regards to the survival, pluripotency and neural differentiation of meSCs.

关键词： transient receptor potential canonical subfamily member 3 (TRPC3) mouse embryonic stem cells (meSCs) neurondifferentiation CRISPR/Cas9 pluripotency apoptosis mitochondrial membrane potential

Ab initio calculations of the elastic,electronic,optical,and vibrational properties of PdGa compound under pressure

在线全文

学校读者我要写书评

暂无评论

Chinese Physics B 2012年第9期21卷 422-429页

作者： h. Koc A. Yildirim e. Deligoz Department of Physics Siirt University Department of Physics Aksaray University

The structural, elastic, electronic, optical, and vibrational properties of cubic PdGa compound are investigated using the norm-conserving pseudopotentials within the local density approximation （LDA） in the framework of the density functional theory. The calculated lattice constant has been compared with the experimental value and has been found to be in good agreement with experimental data. The obtained electronic band structures show that PdGa compound has no band gap. The second-order elastic constants have been calculated, and the other related quantities such as the Young＇s modulus, shear modulus, Poisson＇s ratio, anisotropy factor, sound velocities, and Debye temperature have also been estimated. Our calculated results of elastic constants show that this compound is mechanically stable. Furthermore, the real and imaginary parts of the dielectric function and the optical constants such as the electron energy-loss function, the optical dielectric constant and the effective number of electrons per unit cell are calculated and presented in the study. The phonon dispersion curves are also derived using the direct method.

关键词： PdGa vibrational properties optical properties elastic constants

Tetracycline-inducible protein expression in pancreatic cancer cells: effects of CapG overexpression

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2011年第15期17卷 1947-1960页

作者： sarah Tonack Sabina Patel Mehdi Jalali Taoufik Nedjadi Rosalind e Jenkins Christopher Goldring John Neoptolemos eithne Costello Liverpool CR-UK Centre Department of Molecular and Therapeutic Cancer MedicineUniversity of Liverpool Liverpool L69 3GA United Kingdom MRC Centre forDrug Safety Science Department of Pharmacology and Therapeutics School of Biomedical Sciences University of Liverpool L69 3GA United Kingdom National Institute for health Research Pancreatic Biomedical Research Unit Liverpool L69 3GA United Kingdom

AIM: To establish stable tetracycline-inducible pancreatic cancer cell lines. MeThODS: Suit-2, MiaPaca-2, and Panc-1 cells were transfected with a second generation reverse tetracycline-controlled transactivator protein (rtTA2S-M2), under the control of either a cytomegalovirus (CMV) or a chicken β-actin promoter, and the resulting clones were ***: Use of the chicken (β-actin) promoter proved superior for both the production and maintenance of doxycycline-inducible cell lines. The system proved versatile, enabling transient inducible expression of a variety of genes, including GST-P, CYP2e1, S100A6, and the actin capping protein, CapG. To determine the physiological utility of this system in pancreatic cancer cells, stable inducible CapG expressors were established. Overexpressed CapG was localised to the cytoplasm and the nuclear membrane, but was not observed in the nucleus. high CapG levels were associated with enhanced motility, but not with changes to the cell cycle, or cellular proliferation. In CapG-overexpressing cells, the levels and phosphorylation status of other actin-moduating proteins (Cofilin and ezrin/Radixin) were not altered. however, preliminary analyses suggest that the levels of other cellular proteins, such as ornithine aminotransferase and enolase, are altered upon CapG induction. CONCLUSION: We have generated pancreatic-cancer derived cell lines in which gene expression is fully controllable.

关键词： Pancreatic cancer cells Tetracycline-inducible CapG Suit-2 Panc-1 MiaPaCa-2

Impurity effects on electrical conductivity of doped bilayer graphene in the presence of a bias voltage

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics B 2016年第7期25卷 316-323页

作者： e Lotfi h Rezania B Arghavaninia M Yarmohammadi Department of Physics Sanandaj Branch Islamic Azad University Department of Physics Razi University Department of Physics Kermanshah Branch Islamic Azad University Young researchers and elite Club Kermanshah Branch Islamic Azad University

We address the electrical conductivity of bilayer graphene as a function of temperature, impurity concentration, and scattering strength in the presence of a finite bias voltage at finite doping, beginning with a description of the tight-binding model using the linear response theory and Green＇s function approach. Our results show a linear behavior at high doping for the case of high bias voltage. The effects of electron doping on the electrical conductivity have been studied via changing the electronic chemical potential. We also discuss and analyze how the bias voltage affects the temperature behavior of the electrical conductivity. Finally, we study the behavior of the electrical conductivity as a function of the impurity concentration and scattering strength for different bias voltages and chemical potentials respectively. The electrical conductivity is found to be monotonically decreasing with impurity scattering strength due to the increased scattering among electrons at higher impurity scattering strength.

关键词： bilayer graphene Green's function electrical conductivity

Iron fractions in the apoplast of intact root tips of Zea mays L. seedlings affected by nitrogen form

在线全文

学校读者我要写书评

暂无评论

Chinese Science Bulletin 2002年第9期47卷 727-731页

作者： h.e.Goldbach Institute of Agrichemistry Bonn University

The effects of ammonium (Nh4+-N) and nitrate (NO3- - N) were examined on Fe fractions and FeCN (ferricyanide) reductase activity in intact root tips (0-3 cm) of young maize (Zea mays L. cv. Lenz) in solution culture by using short-term experiment under controlled Fe deficiency conditions (containing high hCO3- concentration in pre-culture solution). The results showed that Fe(Ⅱ) concentrations in root tip apoplast of maize were only 20-40 nmol/g FW which accounted for 7%-13% of total Fe. Most of Fe in root tips existed as Fe(Ⅲ) compounds. Imposition of the roots to Nh4+ - N or NO3- - N for 60 min led to an increase of Fe(Ⅱ) in root tip apoplast. Nh4+ - N led to an increased concentration of Fe(Ⅱ) and exchangeable Fe (Fe(Ⅱ) and Fe (Ⅲ)) in root tips, while NO3- - N increased FeCN reductase activity. The relationship between ph and Fe fractions, FeCN reductase activity was also discussed.

关键词： root apoplast iron fraction nitrogen form.

In vitro corrosion-fatigue behavior of biodegradable Mg/hA composite in simulated body fluid

在线全文

学校读者我要写书评

暂无评论

Journal of Magnesium and Alloys 2021年第6期9卷 2169-2184页

作者： e.Ghazizadeh A.h.Jabbari M.Sedighi School of Mechanical engineering Iran University of Science and TechnologyNarmakTehranIran

Magnesium and its composites as biodegradable materials offer especial capabilities to be used as bio-absorbable ***,their poor corrosion and fatigue properties in the physiological environment can restrict their *** this study,corrosion-fatigue tests have been performed on the extruded magnesium and magnesium/hydroxyapatite(Mg/hA)composites in a high cycle *** produce the composites,pure magnesium was reinforced by 2.5 wt.%and 5 wt.%of hydroxyapatite submicron particles using an electromagneticmechanical stirring method and hot extrusion *** experimental density measurement exhibits that the porosity increases in the extruded samples with more hydroxyapatite *** investigate the corrosion and corrosion-fatigue behavior of the specimens,simulated body fluid(SBF)was used during in vitro *** results of the potentiodynamic polarization corrosion test show that the composite with 2.5 wt.%of hydroxyapatite(Mg/2.5 wt.%hA)and the pure magnesium specimen exhibit the highest and the lowest corrosion resistance,*** the elemental mapping analysis of the corroded samples,this behavior could be due to the formation of strong phosphorus-calcium based layers on the composite *** results obtained from the mechanical tests indicate that Mg/5 wt.%hA offered the highest tensile and compressive yield strengths,as well as the most promising high cycle fatigue *** the corrosionfatigue test,the simultaneous effects of fatigue and corrosion damages led to a similar corrosion-fatigue behavior in both *** fracture surfaces of the corrosion-fatigue samples suggest that the cracks are initiated in the corroded regions of the samples surface,which reduces the crack initiation step and subsequently decreases the fatigue *** comparison with the pure magnesium,both composites exhibit more promising corrosion and corrosion-fatigue behaviors with a significant fatigue life improvement in the ph

关键词： Magnesium Magnesium/hydroxyapatite composite Corrosion Biodegradation high cycle fatigue Corrosion-fatigue

Infection does not increase long-term mortality in patients with acute severe alcoholic hepatitis treated with corticosteroids

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2017年第11期23卷 2052-2059页

作者： Ashwin D Dhanda Ashish Sinha Vicky hunt sarah Saleem Matthew e Cramp Peter L Collins Institute of Translational and Stratified Medicine Plymouth University Peninsula Schools of Medicine and Dentistry South West Liver Unit Plymouth Hospitals NHS Trust Department of Liver Medicine University Hospitals Bristol NHS Foundation Trust

AIM To determine whether infection in patients with acute severe alcoholic hepatitis(AAh) treated with corticosteroids is associated with increased *** Consecutive patients with AAh were treated with steroids and recruited to the study. Clinically relevant infections(body temperature > 38 ℃ or e than 4 h, ascitic neutrophil count > 0.25 ×109/L, consolidation on chest radiograph or clinically relevant positive microbiological culture of bodily fluid) were recorded prospectively. Clinical and laboratory parameters were recorded and survival at 90 d and 6 mo was determined. Univariate analysis of factors associated with 90-d mortality was performed and significant variables included in a multivariate *** Seventy-two patients were included in the final analysis(mean age 47.9 years, 26% female, mean discriminant function 53.0). Overall mortality in the group occurred in 15(21%), 23(32%) and 31(43%) at day 28, day 90 and 1 year respectively. 36(50%) had a clinically relevant infection during their hospitalisation(23 after initiation of steroids). The median time to development of incident infection after commencement of steroids was 10 d. The commonest site of infection was ascites(31%) and bacteraemia(31%) followed by urinary tract(19%) and respiratory tract(8%). Forty-one separate organisms were isolated in 33 patients; the most frequent genus was escherichia(22%) and enterococcus(20%). Infection was not associated with 90-d or 1 year mortality but was associated with higher creatinine, model for end-stage liver disease and Lille score. Baseline urea was the only independent predictor of 90-d *** Clinically relevant infections are common in patients with AAh but are not associated with increased 90-d or 1 year mortality.

关键词： Alcoholic hepatitis escherichia Infection Lille score Corticosteroids