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Protease inhibitors:recent advancement in its usage as a potential biocontrol agent for insect pest management

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Insect Science 2020年第2期27卷 186-201页

作者： Sujata singh Archana singh Sumit kumar Pooja Mittal Indrakant k.singh Molecular Biology Research Laboratory Department of ZoologyDeshbandhu CollegeUniversity of DelhiKalkajiNew DelhiIndia Department of Botany Hans Raj CollegeUniversity of DelhiDelhiIndia

Plant derived protease inhibitors(PIs)are a promising defensin for crop im-provement and insect pest *** agronomist made significant efforts in utilizing PIs for managing insect *** potentials of PIs are still *** ability to compensate nutrient starvation induced by dietary PI feeding using different strategies,that is,overexpression of PI-sensitive protease,expression of PI-insensitive proteases,degradation of PI,has made this innumerable collection of PIs worthless.A practical challenge for agronomist is to identify potent PI candidates,to limit insect compensatory responses and to elucidate insect compensatory and resistance mechanisms activated upon *** knowledge could be further efficiently utilized to identify potential targets for RNAi-mediated pest *** vital genes of insects could be functionally anno-tated using the advanced gene-editing technique,CRISPR/*** research is exploiting different in silico and modern molecular biology techniques to utilize PIs in controlling insect pests *** review is structured to update recent advancements in this field,along with is chronological background.

关键词： gene stacking insect pest management PI transgenic proteases protease inhibitors transplastomic

Inflammation and retinal degenerative diseases

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Neural Regeneration Research 2023年第3期18卷 513-518页

作者： Geetika kaur Nikhlesh k.singh Integrative Biosciences Center Wayne State UniversityDetroitMIUSA Department of Ophthalmology Visual and Anatomical SciencesWayne State University School of MedicineDetroitMIUSA

Vision is an ability that depends on the precise structure and functioning of the *** kind of stress or injury can disrupt the retinal architecture and leads to vision impairment,vision loss,and *** system and immune response function maintain homeostasis in the *** genetic,metabolic,and environmental factors may alter retinal homeostasis,and these events may initiate various inflammatory *** prolonged inflammatory state may contribute to the initiation and development of retinal disorders such as glaucoma,age-related macular degeneration,diabetic retinopathy,and retinitis pigmentosa,which pose a threat to *** the current review,we attempted to provide sufficient evidence on the role of inflammation in these retinal ***,this review paves the way to focus on therapeutic targets of the disease,which are found to be promising.

关键词： age-related macular degeneration diabetic retinopathy glaucoma retina retinal degeneration retinitis pigmentosa

Anisotropic Bianchi Type-ⅠModel with a Varying A Term

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Chinese Physics Letters 2012年第3期29卷 41-43页

作者： R.k.Tiwari Divya singh Department of Mathematics Govt.Model Science College RewaM.P.486001India

Einstein field equations with variable gravitational and cosmological constants are considered in the presence of a perfect fluid for a Bianchi type-I universe by assuming that the cosmological term is proportional to the Hubble parameter..The variation law for vacuum density was recently proposed by Schützhold on the basis of quantum field estimation in a curved expanding *** cosmological term tends asymptotically to a genuine cosmological constant and the model tends to a de Sitter *** obtain that the present universe is accelerating with a large fraction of cosmological density in the form of a cosmological term.

关键词： universe parameter gravitational

Effects of Large-Scale Climatic Oscillations on the Variability of the Indian Summer Monsoon Rainfall

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Journal of Meteorological Research 2023年第3期37卷 341-352页

作者： Deepak MEENA Athira k Sarmistha singh Department of Civil Engineering Indian Institute of TechnologyPalakkadKerala 678557India

In India,large-scale climatic oscillations have strong influences on the Indian summer monsoon rainfall(ISMR),which plays a crucial role in India’s agricultural production and economic ***,there are limited studies in India that explore the influences of decadal and multidecadal oscillations on the ISMR and associated El Niño–Southern Oscillation(ENSO).Therefore,in this study we carried out a comprehensive and detailed investigation to understand the influences of ENSO,Pacific decadal oscillation(PDO),and Atlantic multidecadal oscillation(AMO)on ISMR across different regions in *** statistical significance of ISMR associated with different phases(positive/warm and negative/cold)of ENSO,PDO,and AMO(individual analysis),and combined ENSO–AMO,and ENSO–PDO(coupled analysis)were analysed by using the nonparametric Wilcoxon Rank Sum(WRS)*** individual analysis results indicate that in addition to the ENSO teleconnection,AMO and PDO significantly affect the spatial patterns of *** analysis was performed to understand how the phase shift of PDO and AMO has modulated the rainfall during El Niño and La Niña *** results indicate that the La Niña associated with a positive PDO phase caused excessive precipitation of about 21%–150%in the peninsular,west–central,and hilly regions compared to the individual effect of ENSO/PDO/AMO on ISMR;similarly,the west–central,coastal,and northwest regions received 15%–56%of excessive ***,during the El Niño combined with PDO positive(AMO positive),above-normal precipitation was observed in hilly,northeast,and coastal(hilly,northeast,west–central,and coastal)regions,opposite to the results obtained from the individual ENSO *** study emphasizes the importance of accounting the decadal and multidecadal forcing when examining variations in the ISMR during different phases of ENSO events.

关键词： climatic oscillation Indian summer monsoon rainfall(ISMR) El Niño-Southern Oscillation(ENSO) Atlantic multidecadal oscillation(AMO) Pacific decadal oscillation(PDO) Wilcoxon Rank Sum(WRS)test

Osteoarticular sequlae of small pox:a case report

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Asian Pacific Journal of Tropical Medicine 2010年第12期3卷 1001-1003页

作者： Pradeep k singh Department of Orthopaedics and Trauma DMIMS WardhaIndia

Small pox has been eradicated completely but its unique pathology and sequlae still come across in routine clinical *** changes following small pox infection has been elaborated in *** present a similar but rare patient with osteomyelitis variolosa and joint deformity involving elbow,wrist joints and humerus *** condyles were typically elongated as central portion of distal humerus *** united uneventfully following stabilization with dynamic compression plate and bone *** showed satisfactory elbow function at the end of last follow-up.

关键词： Osteomyelitis variolosa Small pox Variola virus Deformity

Rayleigh-type wave propagation through liquid layer over corrugated substrate

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Applied Mathematics and Mechanics(English Edition) 2017年第6期38卷 851-866页

作者： A.k.singh A.DAS A.RAY Department of Applied Mathematics Indian Institute of Technology(ISM)

The propagation of the Rayleigh-type wave in a fluid layer overlying a corrugated substrate is studied. The corrugated substrate is considered as a fluid satu- rated poroelastic substrate and a quadratically heterogeneous isotropic elastic substrate in Case I and Case II, respectively. Closed form expressions of dispersion relation for Case I and Case II ave obtained. The influence of corrugation, porosity, and hetero- geneity on the phase velocity of Rayleigh-type wave, for both cases, is highlighted and demonstrated through numerical computation and graphical discussion. Neglecting cor- rugation at the common interface, expressions of phase velocity of the Rayleigh-type wave for both cases ave derived in a closed form as a special case of the problem. Comparison between the presence and the absence of both heterogeneity and poroelasticity in the substrate of the composite structure is a key in the present study.

关键词： Rayleigh-type wave porosity heterogeneity corrugation

Thermomechanical Control Process and Its Effect on Structure and Properties of High Strength Low Alloy Steels

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Journal of Iron and Steel Research International 2011年第S1期18卷 511-520页

作者： singh R k P Director Kalyani Centre for Technology & innovationSurvey No.15Ahead of Renuka Mata MandirKeshavnagarPuneIndia - 411036

Low carbon steels microalloyed with small amount of carbide and/or nitride forming elements such as Nb,Ti and V with Thermomechanical controlled processing (TMCP) can give fine grained ferrite structure with high strength and superior *** present study was aimed at identifying rolling parameters as well as microstructural characterization for accomplishing high yield strength and high charpy impact property at-60℃ by controlling hot rolling parameters and microstructure Grain size distribution was also monitored and related to mechanical properties of steel.

关键词： HSLA steel thermomechanical control processing grain refining precipitation recrystalization

Virtual reality based apps are the future of patient:Counseling

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World Journal of Clinical Cases 2025年第6期13卷 58-60页

作者： Ranjan k Behera Arvind k Morya Parul C Gupta Arshi singh Department of Ophthalmology MMIMSR Mullana AmbalaAmbala 133207HaryānaIndia Department of Ophthalmology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia Department of Ophthalmology Post Graduate Institute of Medical Education and ResearchChandigarh 160012PunjabIndia Department of Ophthalmology Guru Nanak Eye CentreNew Delhi 110001New DelhiIndia

The use of virtual reality to educate preoperative patients has a positive impact on nurses as well as patients undergoing *** can help improve patient satisfaction and improve favorable outcomes by reducing patient anxiety and proving adequate knowledge about the procedure and possible outcomes to the *** also reduces burden on nursing staff and *** and more diverse cohort studies will help us understand the wider application of this tool on the patient *** may be difficult to apply this tool on elderly patients with failing eyesight,multiple physical ***,there may be reduced acceptance of this modality by older nursing staff and practitioners who may prefer the traditional verbal version for *** will benefit from a combined approach of using virtual reality apps with tradition one-on-one counselling to help alleviate patient concerns and improve patient and healthcare professional satisfaction.

关键词： Nurse Patient Virtual reality Counselling Healthcare

On the Urbach's formula for evaluation of electron trapping parameter:The case of persistent luminescent materials

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Journal of Rare Earths 2017年第8期35卷 733-738页

作者： Ngangbam Chandrasekhar k.Bishal singh R.k.Gartia Department of Physics Manipur University Imphal-795003 Manipur India

Urbach’s formula for evaluation of electron trapping parameter that happens to be the earliest has emerged as a popular method amongst researchers of persistent luminescence. In this study, we analysed the thermoluminescence curves of glow-in-the-dark phosphors. Those included some curves recorded by us and others that solely used the Urbach’s formula. Using the parameter obtained by rigorous analysis by fitting the whole TL curves, we presented a comprehensive picture of the potentialities and limitations of the simple Urbach’s relation E=T_m/500, where E is the trap-depth and T_m the peak temperature in absolute scale, first proposed by Urbach in 1930. Some simple thumb rules on the use of the formula were presented for beginners as well as non-specialists so that entry of physically unrealistic data into the literature was prevented.

关键词： Urbach’s formula electron-trapping parameter glow-in-the-dark phosphor afterglow rare earths