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Crystal Facet Engineering of TiO_(2) Nanostructures for Enhancing Photoelectrochemical Water Splitting with BiVO_(4) Nanodots

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Nano-Micro Letters 2022年第3期14卷 201-215页

作者： Mi Gyoung Lee Jin wook Yang Hoonkee park Cheon Woo Moon Dinsefa M.Andoshe Jongseong park Chang‑Ki Moon Tae Hyung Lee Kyoung Soon Choi Woo Seok Cheon Jang‑Joo Kim Ho Won Jang Department of Materials Science and Engineering Research Institute of Advanced MaterialsSeoul National UniversitySeoul 08826Republic of Korea Department of Chemistry and Nanoscience Ewha Womans UniversitySeoul 03693Republic of Korea National Research Facilities and Equipment Center Korea Basic Science InstituteDaejeon 34133Republic of Korea Advanced Institute of Convergence Technology Seoul National UniversitySuwon 16229Republic of Korea

Although bismuth vanadate(BiVO4)has been promising as photoanode material for photoelectrochemical water splitting,its charge recombination issue by short charge diffusion length has led to various studies about heterostructure *** a hole blocking layer of BiVO4,titanium dioxide(TiO_(2)) has been considered unsuitable because of its relatively positive valence band edge and low electrical ***,a crystal facet engineering of TiO_(2) nanostructures is proposed to control band structures for the hole blocking layer of BiVO4 *** design two types of TiO_(2) nanostructures,which are nanorods(NRs)and nanoflowers(NFs)with different(001)and(110)crystal facets,respectively,and fabricate BiVO4/TiO_(2) heterostructure *** BiVO4/TiO_(2) NFs showed 4.8 times higher photocurrent density than the BiVO4/TiO_(2) *** decay time analysis and time-resolved photoluminescence reveal the enhancement is attributed to the reduced charge recombination,which is originated from the formation of type II band alignment between BiVO4 nanodots and TiO_(2) *** work provides not only new insights into the interplay between crystal facets and band structures but also important steps for the design of highly efficient photoelectrodes.

关键词： Crystal facet control Bismuth vanadate Titanium dioxide Heterojunction Water splitting

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Simple reactor for the synthesis of silver nanoparticles with the assistance of ethanol by gas-liquid discharge plasma

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Plasma Science and Technology 2019年第4期21卷 34-43页

作者： Pan LU Dong-wook KIM Dong-Wha park Department of Chemistry and Chemical Engineering Inha University100 Inha-Ro.Michuhol-guIncheon 22212Republic of Korea Regional Innovation Center for Environmental Technology of Thermal Plasma(RIC-ETTP: Inha University100 Inha-RoMichuhol-gu.Incheon 22212.Republic of Korea

Atmospheric pressure plasma technology is gaining increasing importance because it is a simple and tunable synthesis process for the production of metallic *** addition to the development of the power supply,improving the reactor is also one of the main strategies to enhanee the *** this study,a simple reactor for the gas-liquid discharge plasma induced by argon gas was applied to synthesize silver nanopailicles from silver nitrate(AgNO3)in *** AC power supply with a peak voltage of 3.5 kV was *** frequency and on-time were set to 50 kHz and 2.5“s,*** oscilloscope showed that the rising time was approximately 2“*** ethanol was used as the source for the reactive reducing *** more additional comp on ents existed in the solution during the discharge and neither of the electrodes was in contact with the treated *** temperature in creased by 10°C within 1 min without a cooling *** was the main impurity and was expected to be produced from the decomposition of the organics under the *** elevated temperature decreased the organic by-products by evaporation and could also decrease the production of *** electron microscopy showed that the spherical silver nanoparticles with a size of approximately 10 nm were synthesized with a crystal structure and that a low concentration of ethanol prefers the production of the mono-dispersed colloid.

关键词： silver nanoparticles synthesis nonthermal plasma ethanol reduction gas-liquid discharge

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Measuring the Needs for Medical Service in the Retirement Residential Community in Korea

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Journal of Building Construction and Planning Research 2017年第3期5卷 116-127页

作者： SoIm park Kyung wook Seo Division of Universal Design & Senior Housing Korea Research Institute of Eco-Environmental Architecture Seoul Korea Department of Architecture & Built Environment Northumbria University Newcastle upon Tyne UK

Medical facilities in retirement residential areas provide diverse medical and health-related services to retirees, and they are equipped and programed with various medical services for enhancing retirees’ daily activities. To find out the current status of using medical facilities by retirees, this study surveyed retirees in their fifties, sixties, and seventies, who live in Eunpyeong-gu, Seoul. The survey data was sorted by the types of medical facilities they visit, reasons for their visit, and the types of medical facilities in a retirement residential area they would prefer to visit. The pros and cons of using private and general hospitals can be evaluated further to set up the right strategy to reconcile them;and each type of hospital can be improved by adding those missing elements that the interviewees mentioned. In the broad perspective, this indicates the need to suggest the direction of preparing residential areas that are technically planned for retirees on the basis of the analysis of Korean retirees’ needs.

关键词： Urban Retirees Baby-Boomer Retirement Residential Area Neighborhood Regeneration Age-Friendly Facility Medical Service Universal Design Barrier-Free Design

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Prognostic significance of the neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in patients with stage Ⅲ and Ⅳcolorectal cancer

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World Journal of Gastroenterology 2017年第3期23卷 505-515页

作者： Jae Hyun Kim Jun Yeop Lee Hae Koo Kim Jin wook Lee Sung Gyu Jung Kyoungwon Jung Sung Eun Kim Won Moon Moo In park Seun Ja park Division of Gastroenterology Department of Internal MedicineKosin University College of MedicineBusan 602-702South Korea

AIM To evaluate the prognostic value of the neutrophil-tolymphocyte ratio(NLR) and platelet-to-lymphocyte ratio(PLR) in patients with colorectal cancer(CRC).METHODS Between April 1996 and December 2010, medical records from a total of 1868 patients with CRC were retrospectively reviewed. The values of simple inflammatory markers including NLR and PLR in predicting the long-term outcomes of these patients were evaluated using Kaplan-Meier curves and Cox regression *** The median follow-up duration was 46 mo(interquartile range, 22-73). The estimation of NLR and PLR was based on the time of diagnosis. In multivariate Cox regression analysis, high NLR (≥ 3.0) and high PLR(≥ 160) were independent risk factors predicting poor long-term outcomes in patients with stage Ⅲ and Ⅳ CRC. However, high NLR and high PLR were not prognostic factors in patients with stage Ⅰ and Ⅱ *** In this study, we identified that high NLR (≥ 3.0) and high PLR (≥ 160) are useful prognostic factors to predict long-term outcomes in patients with stage Ⅲ and Ⅳ CRC.

关键词： Colorectal cancer Neutrophil Lymphocyte Platelet Prognosis

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Improving Urban Retirees’ Well-Being by Leisure Activities

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Journal of Building Construction and Planning Research 2017年第3期5卷 99-115页

作者： SoIm park Kyung wook Seo Division of Universal design & Senior Housing Korea Research Institute of Eco-Environmental Architecture Seoul Korea Department of Architecture & Built Environment Northumbria University Newcastle upon Tyne UK

This research is to investigate urban retirees’ needs and suggest the design direction of leisure facilities. Unlike the existing approach based on deterioration of physical ability, this will allow a new type of suggestion to enable the retirees to live their second lives in a more creative way. By analyzing their common memories and events, it was found that they developed their desire for leisure from their experience of wealth and economic growths. Some preceding research pointed out that their actual leisure activities tend to be static and passive in general. Through the interview, however, this research has found that there are 45 indoor activities and 75 outdoor leisure activities, while their potential demands for leisure further extends to 88. With outdoor activities outnumbering indoor activities, the result shows the opposite tendency to the preceding research. On the other hand, their potential demands for leisure further extended to include more intellectually stimulating learning activities.

关键词： Urban Retirees Lifetime Lifestyle Compact City Regeneration Retirement Residential Area Leisure Activities

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Traumatic neuroma of remnant cystic duct mimicking duodenal subepithelial tumor:A case report

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World Journal of Clinical Cases 2020年第17期8卷 3821-3827页

作者： Dong-Hwan Kim Ji-Ho park Jin-Kyu Cho Jung-wook Yang Tae-Han Kim sang-Ho Jeong Young-Hye Kim Young-Joon Lee Soon-Chan Hong Eun-Jung Jung Young-Tae Ju Chi-Young Jeong Ju-Yeon Kim Department of Surgery Gyeongsang National University College of MedicineGyeongsang National University HospitalJinju 52727South Korea Department of Pathology Gyeongsang National University College of MedicineGyeongsang National University HospitalJinju 52727South Korea

BACKGROUND Gastrointestinal subepithelial tumors(GSTs),incidentally detected during upper gastrointestinal(GI)endoscopy,may be lesions derived from the GI wall or may be caused by compression from external *** general,traumatic neuroma is a benign nerve tumor that results from postoperative nerve injury,occurring in the bile duct as one of the complications after *** is the first case report demonstrating that neuroma of the cystic duct can be incorrectly perceived as a duodenal subepithelial tumor by compressing the duodenal *** SUMMARY We report the case of a 72-year-old man with traumatic neuroma of the cystic duct after *** tumor was mistaken for a duodenal subepithelial tumor on preoperative upper GI endoscopy and endoscopic ultrasonography due to external compression of the GI *** patient had no symptoms,and his laboratory test results were ***,in a series of follow-up endoscopies,the tumor was found to have grown in size,so it was surgically *** lesion was completely removed by laparoscopic endoscopic cooperative *** patient was discharged on postoperative day 7 without *** Traumatic neuroma of the cystic duct can be mistaken for GSTs in GI endoscopy.

关键词： Case report Neuroma Tumor Endoscopy Laparoscopy Cholecystectomy

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Enhanced delivery of a low dose of aducanumab via FUS in 5×FAD mice,an AD model

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Translational Neurodegeneration 2022年第1期11卷 31-45页

作者： Chanho Kong Eun-Jeong Yang Jaewoo Shin Junwon park Si-Hyun Kim Seong-wook park Won Seok Chang Chang-Han Lee Hyunju Kim Hye-Sun Kim Jin Woo Chang Department of Neurosurgery Yonsei University College of Medicine50 Yonsei-RoSeodaemun-GuSeoulRepublic of Korea Department of Pharmacology College of MedicineSeoul National University103 DaehakroJongro-GuSeoulRepublic of Korea Neuroscience Research Center College of MedicineSeoul National University103 DaehakroJongro-GuSeoulRepublic of Korea Department of Biomedical Sciences College of MedicineSeoul National University103 DaehakroJongro-GuSeoulRepublic of Korea Bundang Hospital Seoul National University College of MedicineBundang-GuSungnamRepublic of Korea.

Background:Aducanumab(Adu),which is a human IgG1 monoclonal antibody that targets oligomer and fibril forms of beta-amyloid,has been reported to reduce amyloid pathology and improve impaired cognition after administration of a high dose(10 mg/kg)of the drug in Alzheimer’s disease(AD)clinical *** purpose of this study was to investigate the effects of a lower dose of Adu(3 mg/kg)with enhanced delivery via focused ultrasound(FUS)in an AD mouse ***:The FUS with microbubbles opened the blood-brain barrier(BBB)of the hippocampus for the delivery of *** combined therapy of FUS and Adu was performed three times in total and each treatment was performed biweekly.Y-maze test,Brdu labeling,and immunohistochemical experimental methods were employed in this *** addition,RNA sequencing and ingenuity pathway analysis were employed to investigate gene expression profiles in the hippocampi of experimental ***:The FUS-mediated BBB opening markedly increased the delivery of Adu into the brain by approximately 8.1 times in the *** combined treatment induced significantly less cognitive decline and decreased the level of amyloid plaques in the hippocampi of the 5×FAD mice compared with Adu or FUS *** treatment with FUS and Adu activated phagocytic microglia and increased the number of astrocytes associated with amyloid plaques in the hippocampi of 5×FAD ***,RNA sequencing identified that 4 enriched canonical pathways including phagosome formation,neuroinflammation signaling,CREB signaling and reelin signaling were altered in the hippocami of 5×FAD mice receiving the combined ***:In conclusion,the enhanced delivery of a low dose of Adu(3 mg/kg)via FUS decreases amyloid deposits and attenuates cognitive function ***-mediated BBB opening increases adult hippocampal neurogenesis as well as drug *** present an AD treatment strategy through the synergistic effect of the combined therapy of

关键词： Aducanumab Alzheimer’s disease Focused ultrasound Transcriptome profiling

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Recovery of brachial plexus injury after bronchopleural fistula closure surgery based on electrodiagnostic study:A case report and review of literature

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World Journal of Clinical Cases 2022年第30期10卷 11090-11100页

作者： Young-In Go Da-Sol Kim Gi-wook Kim Yu Hui Won Sung-Hee park Myoung-Hwan Ko Jeong-Hwan Seo Department of Physical Medicine&Rehabilitation Jeonbuk National University Medical SchoolJeonju 54907South Korea Research Institute of Clinical Medicine of Jeonbuk National University Biomedical Research Institute of Jeonbuk National University HospitalJeonju 54907South Korea

BACKGROUND Axillary thoracotomy and muscle flap are muscle-and nerve-sparing methods among the surgical approaches to bronchopleural fistula(BPF).However,in patients who are vulnerable to a nerve compression injury,nerve injury may *** this report,we present a unique case in which the brachial plexus(division level),suprascapular,and long thoracic nerve injury occurred after BPF closure surgery in a patient with ankylosing spondylitis and concomitant multiple joint *** SUMMARY A 52-year-old man with a history of ankylosing spondylitis with shoulder joint contractures presented with right arm weakness and sensory impairment immediately after axillary thoracotomy and latissimus dorsi muscle flap surgery for BPF *** the surgery,the patient was positioned in a lateral decubitus position with the right arm hyper-abducted for approximately 6 *** resonance imaging and ultrasound revealed subclavius muscle injury or myositis with brachial plexus(BP)compression and related *** electrodiagnostic study confirmed the presence of BP injury involving the wholedivision level,long thoracic,and suprascapular nerve *** was treated with medication,physical therapy,and ultrasound-guided *** steroid injection at the BP,hydrodissection with 5%dextrose water at the BP and suprascapular nerve,and intra-articular steroid and hyaluronidase injection at the glenohumeral joint were *** postoperative day 194,the pain and arm weakness were resolved,and a follow-up electrodiagnostic study showed marked *** Clinicians should consider the possibilities of multiple nerve injuries in patients with joint contracture,and treat each specific therapeutic target.

关键词： Brachial plexus Electrodiagnosis Physical therapy Surgical flaps Thoracotomy Case report

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Suppression of laser-induced choroidal neovascularization by intravitreal injection of tristetraprolin

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International Journal of Ophthalmology(English edition) 2014年第6期7卷 952-958页

作者： Yong Wun Cho Yong Seop Han In Young Chung Seong Jae Kim Seong wook Seo Ji Myong Yoo Jong Moon park Department of Ophthalmology Gyeongsang National University School of Medicine Gyeongsang Institute of Health Science Gyeongsang National University

AIM: To examine the effect of intravitreal adenoviral vector-mediated tristetraprolin(Ad-TTP) on VEGF m RNA expression in a rat model of laser-induced choroidal ***: Ad-TTP was prepared using a commercial kit. Retinal laser-induced photocoagulation(10 spots per eye) was performed on rats in this experimental choroidal neovascularization(CNV) model. Rats were divided into four groups: control(single intravitreal injection of balanced salt solution, n =10), laser-induced CNV(photocoagulation only, n =20), laser-induced CNV plus Ad-TTP injection(photocoagulation plus a single intravitreal Ad-TTP injection, n =20) and Ad-TTP injection only(n =10). Changes in choroidal morphology were evaluated in ten rats in the laser only and the laser plus Ad-TTP groups. Two weeks after laser injury, the size of CNV was calculated by perfusion with high-molecular-weight fluorescein isothiocyanate(FITC)-dextran. VEGF m RNA expression in retina-choroid tissue from ten rats in each group was measured by reverse transcription polymerase chain reaction(RT-PCR). RESULTS: Two weeks after treatment, the area of laser-induced CNV was reduced by approximately 60% in the rats given the Ad-TTP injection compared with that in the laser-only group. There was a tendency toward decreased VEGF m RNA expression in the Ad-TTP injection ***: A single intravitreal injection of Ad-TTP significantly suppressed CNV size in this experimental laser-induced CNV model. Ad-TTP injection also decreased VEGF m RNA expression compared with that inthe laser-induced CNV group. The present study is meaningful as the first study to investigate the effect of tristetraprolin delivered via intravitreal injection.

关键词： laser-induced choroidal neovascularization tristetraprolin adenoviral vectors

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Sequence Information on Simple Sequence Repeats and Single Nucleotide Polymorphisms through Transcriptome Analysis of Mungbean

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Journal of Integrative Plant Biology 2011年第1期53卷 63-73页

作者： Kyaw Thu Moe Jong-wook Chung Young-Il Cho Jung-Kyung Moon Ja-Hwan Ku Jin-Kyo Jung Jungran Lee Yong-Jin park Department of Plant Resources College of Industrial SciencesKongju National University The Rural Development Administration(RDA) Legume Bio-Resource Center of Green Manure(LBRCGM) Kongju National University

Mungbean （Vigna radiata （L.） Wilczek） is a unique species in its ability to fix atmospheric nitrogen, with early maturity, and relatively good drought resistance. We used 454 sequencing technology for transcriptome sequencing. A total of 150 159 and 142 993 reads produced 5 254 and 6 374 large contigs （〉_500 bp） with an average length of 833 and 853 for Sunhwa and Jangan, respectively. Functional annotation to known sequences yielded 41.34% and 41.74% unigenes for Jangan and Sunhwa. A higher number of simple sequence repeat （SSR） motifs was identified in Jangan （1 630） compared with that of Sunhwa （1 334）. A similar SSR distribution pattern was observed in both varieties. A total of 8 249 single nucleotide polymorphisms （SNPs） and indels with 2 098 high-confidence candidates were identified in the two mungbean varieties. The average distance between individual SNPs was -860 bp. Our report demonstrates the utility of transcriptomic data for implementing a functional annotation and development of genetic markers. We also provide large resource sequence data for mungbean improvement programs.

关键词： Sequence Information on Simple Sequence Repeats and Single Nucleotide Polymorphisms through Transcriptome Analysis of Mungbean SNPs

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