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Non-secretory multiple myeloma expressed as multiple extramedullary plasmacytoma with an endobronchial lesion mimicking metastatic cancer:A case report

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World Journal of Clinical Cases 2022年第22期10卷 7899-7905页

作者： Seul Bi Lee Chi Young Park Hee Jeong Lee Ran Hong Woo shin Kim sang-Gon Park Department of Hemato-oncology Chosun University HospitalGwangju 501-717South Korea Department of Pathology Chosun University HospitalGwangju 501-717South Korea Department of Laboratory Medicine Chosun University HospitalGwangju 501-717South Korea

BACKGROUND Non-secretory multiple myeloma(MM)is a rare condition that accounts for only 3%of MM cases and is defined by normal serum and urine immunofixation and a normal serum free light chain ***-secretory MM with multiple extramedullary plasmacytomas derived from endobronchial lesions is extremely rare and can be misdiagnosed as metastasis of solid *** SUMMARY A 36-year-old man presented with progressive facial swelling and nasal congestion with *** imaging studies revealed an endobronchial mass in the left bronchus and a large left maxillary mass with multiple destructive bone metastatic *** initially presented with lung cancer and multiple ***,pathologic reports showed multiple extramedullary plasmacytomas in the left maxilla and the left *** was no change in the serum and urine monoclonal protein levels,and no abnormalities were observed in laboratory examinations,including hemoglobin,calcium,and creatinine *** bone marrow was hypercellular,with 13.49%plasma *** patient was diagnosed with non-secretory MM expressed as multiple extramedullary plasmacytomas with endobronchial lesions in a rare *** therapy for symptomatic lesions with high-dose dexamethasone was started,and the size of the left maxillary sinus lesion dramatically *** the future,chemotherapy will be administered to control lesions in other *** We present a rare case of non-secretory MM with multiple extramedullary plasmacytoma with an endobronchial lesion.

关键词： Maxillary mass lesion Destructive bone metastatic lesion Multiple extramedullary plasmacytoma Endobronchial lesion Non-secretory multiple myeloma Case report

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EXPLICIT BOUNDS OF EIGENVALUES FOR STIFFNESS MATRICES BY QUADRATIC HIERARCHICAL BASIS METHOD)

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Journal of Computational Mathematics 2003年第2期21卷 113-124页

作者： sang Dong KIM Byeong Chun shin Department of Mathematics Kyungpook National UniversityTaegu 702-701KoreaDepartment of MathematicsChonnam National UniversityGwangju 500-757Korea

The bounds for the eigenvalues of the stiffness matrices in the finite element discretization corresponding to Lu := - u' with zero boundary conditions by quadratic hierarchical basis are shown explicitly. The condition number of the resulting system behaves like O(1/h) where h is the mesh size. We also analyze a main diagonal preconditioner of the stiffness matrix which reduces the condition number of the preconditioned system to O(1).

关键词： hierarchical basis multilevel

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CHEBYSHEV WEIGHTED NORM LEAST-SQUARES SPECTRAL METHODS FOR THE ELLIPTIC PROBLEM

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Journal of Computational Mathematics 2006年第4期24卷 451-462页

作者： sang Dong Kim Byeong Chun shin Department of Mathematics Kyungpook National University Taegu 702-701 Korea Department of Mathematics Chonnam National University Kwangju 500-757 Korea

We develop and analyze a first-order system least-squares spectral method for the second-order elhptic boundary value problem with variable coefficients. We first analyze the Chebyshev weighted norm least-squares functional defined by the sum of the Lw^2- and Hw^-1- norm of the residual equations and then we eplace the negative norm by the discrete negative norm and analyze the discrete Chebyshev weighted least-squares method. The spectral convergence is derived for the proposed method. We also present various numerical experiments. The Legendre weighted least-squares method can be easily developed by following this paper.

关键词： Least-squares methods Spectral method Negative norm.

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COEDA咖啡厅

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城市环境设计 2024年第1期147卷 162-167页

作者：大庭晋小松克仁川澄·小林研二写真事务所

我们随机堆叠8厘米正方形的桧木棒，制作了一个巨大的树状结构。用碳纤维棒加固（抗拉强度是铁的7倍），就有了一个带有巨大枝杈的“树干”，同时能保证在地震期间减少晃动。项目用地位于可以俯瞰太平洋的悬崖上，通过利用树木状的外观...

我们随机堆叠8厘米正方形的桧木棒，制作了一个巨大的树状结构。用碳纤维棒加固（抗拉强度是铁的7倍），就有了一个带有巨大枝杈的“树干”，同时能保证在地震期间减少晃动。项目用地位于可以俯瞰太平洋的悬崖上，通过利用树木状的外观造型，可以避免使用遮挡景观的外围柱子。

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Anesthetics management of a renal angiomyolipoma using pulse pressure variation and non-invasive cardiac output monitoring: A case report

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World Journal of Clinical Cases 2022年第24期10卷 8656-8661页

作者： Woo Jae Jeon Woo Jong shin Young Joon Yoon Chan Woo Park Jae Hang Shim sang Yun Cho Department of Anesthesiolgy and Pain Medicine Hanyang University Guri HospitalGuri-si 471-701Gyeonggi-doSouth Korea

BACKGROUND Hypovolemic shock can lead to life-threatening organ dysfunction,and adequate fluid administration is a fundamental ***,parameters such as vital signs,central venous pressure,and urine output have been used to estimate intravascular ***,pulse pressure variation(PPV)and non-invasive cardiac monitoring devices have been *** this case report,we introduce a patient with massive active bleeding from giant renal angiomyolipoma(AML).During emergent nephrectomy,we used non-invasive cardiac monitoring with CSN-1901(Nihon Kohden,Tokyo,Japan)and PPV to evaluate the patient's intravascular volume status to achieve optimal fluid *** SUMMARY A 30-year-old male patient with giant AML with active bleeding was referred to the emergency room complaining of severe abdominal pain and spontaneous abdominal *** was diagnosed by computed tomography,and emergent nephrectomy was *** bleeding was expected so we decided to use non-invasive cardiac monitoring and PPV to assist fluid therapy because they are relatively easy and fast compared to invasive cardiac *** the surgery,6000 mL of estimated blood loss *** with the patient's vital signs and laboratory results,we monitored cardiac output,cardiac output,stroke volume,stroke volume index with a non-invasive cardiac monitoring device,and PPV using an intra-arterial catheter to evaluate intravascular volume status of the patient to compensate for massive *** In addition to traditional parameters,non-invasive cardiac monitoring and PPV are useful methods to evaluate patient's intravascular volume status and provideguidance for intraoperative management of hypovolemic shock patients.

关键词： Renal angiomyolipoma Pulse pressure variation Cardiac output Case report

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Highly dense and ultrathin gadolinia-doped ceria interlayer for enhanced performance of large-area anode-supported solid oxide fuel cell

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Progress in Natural Science:Materials International 2023年第5期33卷 733-741页

作者： sang Woo shin Amjad Hussain Muhammad Zubair Khan Dong Woo Joh Tak-Hyung Lim Seung-Bok Lee Jong-Eun Hong Joon Hyung Shim Rak-Hyun Song Hydrogen Energy Research Division Korea Institute of Energy Research Department of Mechanical Engineering Korea University Department of Advanced Energy and System Engineering Korea University of Science and Technology(UST) 4. Department of Materials Science & Engineering Pak-Austria Fachhochschule: Institute of Applied Sciences and Technology

The fabrication of a highly dense and ultrathin Gd doped ceria(GDC) interlayer on a large-area, porous electrolyte-coated planar anode support using vacuum slurry coating is studied for application in solid oxide fuel cells(SOFCs). The electrolyte-coated planar anode support body is fabricated by tape casting and pre-sintering is performed at 1100, 1150, and 1200°C. The GDC interlayer is coated onto the pre-sintered electrolyte-coated anode support using a vacuum slurry coating process with different immersion times(30–60 s). A highly dense and ultrathin GDC interlayer with a thickness of 1.48 μm is produced after co-sintering at 1400°C. The 1200°C pre-sintered electrolyte-coated anode support showed a thin and highly dense GDC interlayer which is attributed to a lower shrinkage difference between the coated GDC interlayer and pre-sintered body. The electrochemical performance of a vacuum slurry-coated GDC interlayer cell is 38 % higher compared to that of the screen-printed GDC-coated cell at 700°C due to the greatly reduced Ohmic and electrode polarization resistances. The considerable improvement in the performance is attributed to the ultrahigh GDC density which has prevented the secondary phase formation between the cathode and electrolyte. This study presents the economical, scalable, and reproducible process for the fabrication of highly robust GDC interlayer for the large-area planar anode-supported SOFCs.

关键词： Solid oxide fuel cell Vacuum slurry coating GDC interlayer Sintering Performance

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Enhancing the total organic carbon measurement efficiency for water samples containing suspended solids using alkaline and ultrasonic pretreatment methods

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Journal of Environmental Sciences 2020年第4期32卷 20-28页

作者： Han-Saem Lee Jin Hur Hyun-sang shin Department of Environment Energy Engineering Seoul National University of Science&TechnologySeoul01811South Korea Department of Environment&Energy Sejong UniversitySeoul05006South Korea

In this study,we investigated the effect of sample pretreatments(ultrasonication and alkaline extraction)on total organic carbon(TOC)measurements for water samples containing suspended solids(SS)of four different origins(algae,soil,sewage sludge,and leaf litter)to more clearly assess the impact of particulate organic carbon(POC)in *** effects each of ultrasonication(power,pulse,etc.)and alkaline extraction condition(concentration,time,etc.)on the TOC recovery and precision were investigated,and the results were compared with those of a new sample pre treatment method combining both *** treatment(0.01 mol/L NaOH)showed higher precision than ultrasonication(100/5 on/off pulse),and notably,the differences among the measured TOC values in samples of different origins were also further reduced in the alkaline *** suggests that the ultrasonic pretreatment results can be mainly attributed to the increase in POC recovery through particle size reduction,whereas the alkaline treatment results are achieved through the enhancement of POC *** is also particularly noteworthy that a higher TOC recovery of 87.6%±7.4%with a higher precision of 8.4%could be obtained using the combined method,compared to each treatment(ultrasonic:TOC recovery 34.7%,relative standard deviation 63.1%;alkaline:49.6%and 23.0%,respectively).Thus,simultaneous pretreatment with ultrasonication and alkaline extraction is expected to increase the oxidation rate of organic matter and the homogeneity of the samples,minimizing the loss of POC measurement values,and thereby improving the reliability of the TOC measurements of water samples containing SS.

关键词： Total organic carbon Suspended solids Pretreatment Ultrasonication Alkaline extraction

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采用等通道转角挤压通过晶粒细化同步提高Mg-Zn-Ca合金的耐腐蚀性能和力学性能(英文)

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Transactions of Nonferrous Metals Society of China 2024年

作者：王艺卓罗小萍任广笑王红霞王利飞程伟丽李航鲁小鹏 shin Kwang-seon 太原理工大学材料科学与工程学院太原科技大学材料科学与工程学院山西江淮重工有限责任公司东北大学材料科学与工程学院 Magnesium Technology Innovation Center School of Materials Science and Engineering Seoul National University Gwanak-ro

为了研究显微组织演变对Mg-1Zn-1Ca(wt%)合金的腐蚀行为和强化机制的影响，对铸态Mg-1Zn-1Ca合金分别进行了ECAP一道次和四道次挤压。通过光学显微镜（OM）、通过扫描电子显微镜（SEM）、电子背散射衍射（EBSD）、电化学试验、浸泡试验... 详细信息

为了研究显微组织演变对Mg-1Zn-1Ca(wt%)合金的腐蚀行为和强化机制的影响，对铸态Mg-1Zn-1Ca合金分别进行了ECAP一道次和四道次挤压。通过光学显微镜（OM）、通过扫描电子显微镜（SEM）、电子背散射衍射（EBSD）、电化学试验、浸泡试验和拉伸试验研究了合金的腐蚀行为和力学性能。结果表明，ECAP一道次挤压后，力学性能有所改善，耐腐蚀性能有所下降，这由于ECAP挤压产生了高密度位错和破碎的第二相。相比之下，合金经过ECAP四道次挤压后通过细化晶粒实现了力学性能和耐腐蚀性的同步提升，细晶粒使屈服强度、极限抗拉强度、伸长率和腐蚀速率显著提高，分别达到103MPa、223MPa、30.5%和1.5843mm/y，耐腐蚀性能的增强归因于细晶粒形成致密的腐蚀产物膜以及高密度晶界对腐蚀的阻挡效应。这表明Mg-1Zn-1Ca 合金在生物医学材料中具有广阔的应用前景。

关键词： Mg-Zn-Ca合金等通道转角挤压晶粒细化腐蚀行为力学性能

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Tunable ferroelectricity in oxygen-deficient perovskites with Grenier structure

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npj Computational Materials 2023年第1期9卷 118-125页

作者： Yongjin shin Giulia Galli Pritzker School of Molecular Engineering University of ChicagoChicagoIL 60637USA Department of Chemistry University of ChicagoChicagoIL 60637USA Center for Molecular Engineering and Materials Science Division Argonne National LaboratoryLemontIL 60439USA

Using first-principles calculations,we predict that tunable ferroelectricity can be realized in oxide perovskites with the Grenier structure and ordered oxygen ***,we show that R_(1/3)A_(2/3)FeO_(2.67) solids(where R is a rare-earth ion and A an alkaline-earth cation)exhibit polar phases,with a spontaneous polarization tunable by an appropriate choice of R and *** find that larger cations combined with small R elements lead to a maximum in the polarization and to a minimum in the energy barriers required to switch the sign of the *** arises from cooperative distortions of octahedral and tetrahedral units,where a combination of rotational and sliding modes controls the emergence of polarization within three-dimensional connected *** results indicate that polar Grenier phases of oxide perovskites are promising materials for microelectronic applications and,in general,for the study of phenomena emerging from breaking inversion symmetry in solids.

关键词： polarization ferroelectric structure

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Parameter estimation for building energy models using GRcGAN

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Building Simulation 2023年第4期16卷 629-639页

作者： Hansol shin Cheol-Soo Park Department of Architecture and Architectural Engineering College of EngineeringSeoul National UniversitySeoul08826R.O.Korea Institute of Construction and Environmental Engineering Institute of Engineering ResearchCollege of EngineeringSeoul National UniversitySeoul08826R.O.Korea

Parameter estimation methods can be classified into(1)manual(trial-and-error),(2)numerical optimization(optimization,sampling),(3)Bayesian inference(Bayes filter,Bayesian calibration),and(4)machine learning(generative model).Bayesian calibration has been widely used because it can capture stochastic nature of uncertain ***,the results of Bayesian calibration could be biased by(1)the prior distribution assumed by the expert’s subjective judgment;(2)the likelihood function that cannot always describe the true likelihood;and(3)the posterior distribution approximation method,such as the Markov Chain Monte Carlo,which requires significant computation *** overcome this,a new approach using a generator-regularized continuous conditional generative adversarial network(GRcGAN)is presented in this *** target parameters of the DOE reference building model were *** was trained to estimate uncertain parameters using simulated monthly electricity and gas *** can successfully estimate five uncertain parameters based on 1,000 training data *** proposed approach presents a potential for stochastic parameter estimation.

关键词： generative adversarial networks generative model parameter estimation inverse problem model calibration parameter uncertainty

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