检索结果-南通市图书馆

Biotechnological valorization of algal biomass:an overview

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Systems Microbiology and Biomanufacturing 2021年第2期1卷 131-141页

作者： A.Naresh Kumar Jeong-Jun Yoon Gopalakrishnan Kumar sang-hyoun kim School of Civil and Environmental Engineering Yonsei UniversitySeoul 03722Republic of Korea Intelligent Sustainable Materials R&BD Group Korea Institute of Industrial Technology(KITECH)CheonanChungnam 31056Republic of Korea

Algal biomass has significant advantages over terrestrial plants in terms of CO2 sequestration,biomass productivity,waste-water treatment along with multiple biobased products *** versatility and high carbohydrate content of microalgal biomass act as a potential alternative feedstock to fossil resources and contribute towards the biobased economy *** biomass utilization would play a key role to establish sustainable bioprocess development and technology translation to the industrial *** this framework,the present review discusses the renewable resource potential of algal biomass and its complete utilization for multiple biobased products synthesis in a closed-loop biorefinery *** methods are discussed to obtain high biomass growth and pretreatments to obtain the maximum sugars ***,combined bioprocesses were discussed for the production of biohydrogen,biomethane,bioethanol,short-chain fatty acids(SCFA),medium-chain fatty acids(MCFA),and biopolymers in a closed-loop approach.

关键词： Algal biomass Biorefinery Bioeconomy Closed loop Biohydrogen

Bioelectrochemical system-mediated waste valorization

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Systems Microbiology and Biomanufacturing 2021年第4期1卷 432-443页

作者： K.Chandrasekhar A.Naresh Kumar Tirath Raj Gopalakrishnan Kumar sang-hyoun kim School of Civil and Environmental Engineering Yonsei University50 Yonsei-roSeoul 03722Republic of Korea Faculty of Science and Technology Institute of ChemistryBioscience and Environmental EngineeringUniversity of Stavanger4036 StavangerNorway

Bioelectrochemical systems(BESs)are a new and emerging technology in the field of fermentation *** energy was provided externally to the microbial electrolysis cells(MECs)to generate hydrogen or value-added chemicals,including caustic,formic acid,acetic acid,and ***,BES was designed to recover nutrients,metals or remove recalcitrant *** variety of naturally existing microorganisms and enzymes act as a biocatalyst to induce poten-tial differences amid the *** can be performed with non-catalyzed electrodes(both anode and cathode)under favorable circumstances,unlike conventional fuel *** recent years,value-added chemical producing microbial electrosyn-thesis(MES)technology has intensely broadened the prospect for *** additional strategy includes the introduction of innovative technologies that help with the manufacturing of alternative materials for electrode preparation,ion-exchange membranes,and pioneering *** of this,BES is emerging as a promising *** article deliberates recent signs of progress in BESs so far,focusing on their diverse applications beyond electricity generation and resulting performance.

关键词： Microbial fuel cells Waste valorization Microbial electrolysis cell Waste-to-energy Biofuels

Recovery of the injured neural system through gene delivery to surviving neurons in Parkinson’s disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第10期20卷 2855-2861页

作者： Chanchal Sharma Sehwan kim Hyemi Eo sang Ryong kim School of Life Science Kyungpook National UniversityDaeguKorea BK21 FOUR KNU Creative BioResearch Group Kyungpook National University DaeguKorea Brain Science and Engineering Institute Kyungpook National UniversityDaeguKorea

A critical unaddressed problem in Parkinson’s disease is the lack of therapy that slows or hampers *** medications effectively manage symptoms,they offer no long-term benefit because they fail to address the underlying neuronal *** highlights that the elusive goals of halting progression and restoring damaged neurons limit the long-term impact of current *** clinical trials using gene therapy have demonstrated the safety of various vector delivery systems,dosages,and transgenes expressed in the central nervous system,signifying tangible and substantial progress in applying gene therapy as a promising Parkinson’s disease ***,at diagnosis,many dopamine neurons remain in the substantia nigra,offering a potential window for recovery and *** propose that modulating these surviving dopamine neurons and axons in the substantia nigra and striatum using gene therapy offers a potentially more impactful therapeutic approach for future ***,innovative gene therapies that focus on preserving the remaining elements may have significant potential for enhancing long-term outcomes and the quality of life for patients with Parkinson’s *** this review,we provide a perspective on how gene therapy can protect vulnerable elements in the substantia nigra and striatum,offering a novel approach to addressing Parkinson’s disease at its core.

关键词： adeno-associated virus gene therapy neuroprotection neurorestoration neurotrophic factor nigrostriatal dopamine pathway pro-survival protein

Effective Denoising Architecture for Handling Multiple Noises

在线全文

学校读者我要写书评

暂无评论

Computer Systems Science & Engineering 2023年第3期44卷 2667-2682页

作者： Na hyoun kim Namgyu kim The Graduate School of Business IT of Kookmin University Seoul02707Korea

Object detection,one of the core research topics in computer vision,is extensively used in various industrial *** there have been many studies of daytime images where objects can be easily detected,there is relatively little research on nighttime *** the case of nighttime,various types of noises,such as darkness,haze,and light blur,deteriorate image ***,an appropriate process for removing noise must precede to improve object detection *** there are many studies on removing individual noise,only a few studies handle multiple noises *** this paper,we pro-pose a convolutional denoising autoencoder(CDAE)-based architecture trained on various types of *** also present various composing modules for each noise to improve object detection performance for night *** the exclusively dark(ExDark)Image dataset,experimental results show that the Sequentialfiltering architecture showed superior mean average precision(mAP)compared to other architectures.

关键词： Object detection computer vision nighttime multiple noises convolutional denoising autoencoder

Role of glutathione transferase in phase separation of FUS and TAF15 in neurons

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第7期20卷 1999-2000页

作者： Kiyoung kim Department of Medical Science Soonchunhyang UniversityAsanKorea

Amyotrophic lateral sclerosis(ALS)is a progressive neurodegenerative disorder characterized by the degeneration of motor neurons in the brain and spinal cord,leading to muscle weakness,paralysis,and ultimately death(Cleveland and Rothstein,2001).Frontotemporal lobar degeneration(FTLD)is a neurodegenerative disease affecting the frontal and temporal lobes of the brain,leading to changes in behavior,personality,and language(Van Langenhove et al.,2012).Both ALS and FTLD are classified as proteinopathies in which abnormal protein aggregation and accumulation in neurons contribute to the disease *** in sarcoma(FUS)is a DNA/RNA-binding protein involved in various cellular processes,including transcriptional regulation,RNA splicing,and DNA *** in the FUS gene have been linked to familial ALS,highlighting the importance of FUS in the disease pathogenesis(Vance et al.,2009).In ALS and FTLD,aberrant post-translational modifications(PTMs)of FUS,such as phosphorylation,acetylation,and methylation,have been implicated in the promotion of FUS aggregation and neurotoxicity(Choi et al.,2023).Therefore,understanding the regulatory mechanisms of FUS PTMs is crucial for developing targeted therapies against these diseases.

关键词： degeneration FUS aggregation

Molecules “buckle up” to drive layered hybrid perovskites into single-crystal nanowires in water

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2025年第01期 3-4页

作者： Seokhyoung kim Department of Chemistry Michigan State University

Layered 2D metal halide perovskites (MHPs) are one of the most exciting candidates for next-generation light sources owing to their outstanding optoelectronic properties. These properties are readily tunable by controlling the halide composition, number of inorganic layers, and the chemistry of organic cations. Another key element that can substantially impact the materials’ functionalities is crystal morphology [1].

关键词：

Carboplatin restores neuronal toxicity in FUS-linked amyotrophic lateral sclerosis

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第8期20卷 2319-2320页

作者： Kiyoung kim Department of Medical Science Soonchunhyang UniversityAsanKorea

Amyotrophic lateral sclerosis(ALS),also known as Lou Geh rig's disease,is a progressive neurodegenerative disorder that affects motor neurons in the brain and spinal *** leads to muscle weakness,paralysis,and ultimate... 详细信息

关键词： paralysis sclerosis respiratory

High mobility group box 1 in the central nervous system:regeneration hidden beneath inflammation

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第1期20卷 107-115页

作者： Hanki kim Bum Jun kim Seungyon Koh Hyo Jin Cho Xuelian Jin Byung Gon kim Jun Young Choi Department of Brain Science Ajou University School of MedicineSuwonSouth Korea Department of Biomedical Sciences Ajou University Graduate School of MedicineSuwonSouth Korea Department of Neurology Ajou University School of MedicineSuwonSouth Korea Department of Geriatrics The Affiliated Suqian First People’s Hospital of Nanjing Medical UniversitySuqianJiangsu ProvinceChina

High-mobility group box 1 was first discovered in the calf thymus as a DNA-binding nuclear protein and has been widely studied in diverse fields,including neurology and ***-mobility group box 1 in the extracellular space functions as a pro-inflammatory damage-associated molecular pattern,which has been proven to play an important role in a wide variety of central nervous system disorders such as ischemic stroke,Alzheimer’s disease,frontotemporal dementia,Parkinson’s disease,multiple sclerosis,epilepsy,and traumatic brain *** drugs that inhibit high-mobility group box 1 as a damage-associated molecular pattern,such as glycyrrhizin,ethyl pyruvate,and neutralizing anti-high-mobility group box 1 antibodies,are commonly used to target high-mobility group box 1 activity in central nervous system *** it is commonly known for its detrimental inflammatory effect,high-mobility group box 1 has also been shown to have beneficial pro-regenerative roles in central nervous system *** this narrative review,we provide a brief summary of the history of high-mobility group box 1 research and its characterization as a damage-associated molecular pattern,its downstream receptors,and intracellular signaling pathways,how high-mobility group box 1 exerts the repair-favoring roles in general and in the central nervous system,and clues on how to differentiate the pro-regenerative from the pro-inflammatory *** targeting high-mobility group box 1 in the central nervous system may benefit from differentiating between the two functions rather than overall suppression of high-mobility group box 1.

关键词： central nervous system damage-associated molecular pattern ethyl pyruvate glycyrhizzin high mobility group box 1 inflammation neural stem cells neurodevelopment oligodendrocyte progenitor cells redox status regeneration

Design,Fabrication,and Analysis of Flapping and Folding Wing Mechanism for a Robotic Bird

在线全文

学校读者我要写书评

暂无评论

Journal of Bionic Engineering 2020年第2期17卷 229-240页

作者： Seung Wan Ryu Jong Gu Lee hyoun Jin kim Department of Mechanical&Aerospace Engineering and Automation Systems Research Institute Seoul National UniversitySeoul 08826Republic of Korea

Emulating periodic main wing movement of a bird for generating lift and thrust remains a significant challenge in developing a robotic *** sequences of main wing motion are comprised of flapping,folding,bending,and *** this paper,we concentrate on the flapping and folding motion,and design two wing mechanisms based on a 4-bar linkage structure:one is only for Flapping Motion(FM)and the other is for simultaneous Flapping and Folding Motion(FFM)during a wing *** derive relationships between length and angle of links to analyze kinematic characteristics of the mechanisms and conduct an optimization to select the length parameters of links that allow maximization of the flapping *** run a simulation to confirm the performance of the optimized parameters by examining physical properties,and fabricate two wing mechanisms *** particular,the folding motion is achieved without using an additional *** measurements to investigate a lift profile of each mechanism and their quantitative comparison of the performance of both types confirm the benefits of the folding motion in the perspectives of wing frequency and *** expect that our kinematic formulation,design procedures,and comparative measurement results can help develop a wing mechanism to create a truly biomimetic robotic bird.

关键词： biomimetic robotic bird flapping and folding wing mechanism wing kinematics force measurement