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Discharge Characteristics of Large-Area High-Power RF Ion Source for Positive and Negative Neutral Beam Injectors

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Plasma Science and Technology 2016年第12期18卷 1220-1224页

作者： Doo-Hee CHANG Seung Ho JEONG Min PARK Tae-Seong KIM Bong-Ki JUNG Kwang Won LEE sang ryul in Division of Nuclear Fusion Engineering & Technology Development Korea Atomic Energy Research Institute

A large-area high-power radio-frequency（RF） driven ion source was developed for positive and negative neutral beam injectors at the Korea Atomic Energy Research Institute（KAERI）. The RF ion source consists of a driver region, including a helical antenna and a discharge chamber, and an expansion region. RF power can be transferred at up to 10 kW with a fixed frequency of 2 MHz through an optimized RF matching system. An actively water-cooled Faraday shield is located inside the driver region of the ion source for the stable and steady-state operations of high-power RF discharge. Plasma ignition of the ion source is initiated by the injection of argongas without a starter-filament heating, and the argon-gas is then slowly exchanged by the injection of hydrogen-gas to produce pure hydrogen plasmas. The uniformities of the plasma parameter,such as a plasma density and an electron temperature, are measured at the lowest area of the driver region using two RF-compensated electrostatic probes along the direction of the shortand long-dimensions of the driver region. The plasma parameters will be compared with those obtained at the lowest area of the expansion bucket to analyze the plasma expansion properties from the driver region to the expansion region.

关键词： neutral beam injector RF ion source plasma ignition power loading plasma parameters

Therapeutic effects of Gamma knife radiosurgery for multiple cerebral metastases

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Therapeutic effects of Gamma knife radiosurgery for multiple...

A comparative study on machine learning-based classification to find photothrombotic lesion in histological rabbit brain images

中国抗癌协会神经肿瘤专业委员会第八届学术会议

作者： Se-Hyuk Kim sang ryul Lee Kyung Ah Yang Gamma Knife Center Department of Neurosurgery Ajou University School of Medicine Suwon

＜正＞PURPOSE: The aim of this study is to investigate the therapeutic effects of Gamma Knife radiosurgery（GKRS） in patients with multiple（4 or more） cerebral metastases and to evaluate clinic-radiological and tre...

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Journal of Innovative Optical Health Sciences 2021年第6期4卷 81-89页

作者： sang Hee Jo Yoonhee Kim Yoon Bum Lee Sung Suk Oh Jong-ryul Choi School of Biomedical Engineering Daegu Catholic University(DCU)Gyeongsan 38430Republic of Korea Medical Device Development Center Daegu-Gyeongbuk Medical Innovation Foundation(DGMIF) Daegu 41061Republic of Korea Laboratory Animal Center Daegu-Gyeongbuk Medical Innovation Foundation(DGMIF) Daegu 41061Republic of Korea

Recently,research has been conducted to assist in the processing and analysis of histopathological images using machine learning *** this study,we established machine learning-based algorithms to detect photothrombotic lesions in histological images of photothrombosis-induced rabbit *** machine learning-based algorithms for binary classification were applied,and the accu-racies were compared to classify normal tissues and photothrombotic *** lesion classification model consisting of a 3-layered neural network with a rectified linear unit(ReLU)activation function,Xavier initialization,and Adam optimization using datasets with a unit size of 128×128 pixels yielded the highest accuracy(0.975).In the validation using the tested histological images,it was confirmed that the model could identify regions where brain damage occurred due to photochemical ischemic *** the development of machine learning-based photothrombotic lesion classi-fication models and performance comparisons,we confirmed that machine learning algorithms have the potential to be utilized in histopathology and various medical diagnostic techniques.

关键词： Machine learning histopathological images photothrombotic lesion rabbit brain binary classification logistic regression multi-layer neural networks

DIRECT NUMERICAL SIMULATIONS OF THE DYNAMICS OF PARTICLES WITH ARBITRARY SHAPES IN SHEAR FLOWS

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Journal of Hydrodynamics 2010年第4期22卷 456-465页

作者： CHOI Choeng ryul KIM Chang Nyung Department of Mechanical Engineering Kyung Hee University College of Engineering Kyung Hee University Industrial Liaison Research Institute Kyung Hee University

A fluid-structure interaction method based on the arbitrary Lagrangian-Eulerian method and a dynamic mesh method was developed to simulate the dynamics of a rigid particle in shear *** the method,the governing equations for the fluid flow and particle motion were sequentially solved in a two-way coupling *** mesh system was deformed or re-meshed by the dynamic mesh *** method was employed to simulate the dynamics of a single particle suspended in a flow channel and the dynamics of the particle were *** simulation results show that the angular velocity is not only a function of the inclination angle,is but also influenced by the aspect ratio yielding a hysteresis,while the angular velocity obtained from the Keller-Scalak model is a function only of the inclination angle and does not show a *** present simulations clearly demonstrate that the Fluid-Structure Interaction（FSI） module is very stable,accurate and robust.

关键词： particle suspension Fluid-Structure Interaction (FSI) fluid-particle interaction particulate flow

Artificial intelligence based real-time microcirculation analysis system for laparoscopic colorectal surgery

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World Journal of Gastroenterology 2020年第44期26卷 6945-6962页

作者： sang-Ho Park Hee-Min Park Kwang-ryul Baek Hong-Min Ahn In Young Lee Gyung Mo Son Department of Electronic Engineering Pusan National UniversityBusan 46241South Korea Department of Surgery Pusan National University Yangsan HospitalGyeongsangnam-do 50612South Korea Department of Medicine Pusan National UniversityGyeongsangnam-do 50612South Korea Department of Surgery Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and TechnologyPusan National University Yangsan HospitalYangsan-si 50612South Korea

BACKGROUND Colonic perfusion status can be assessed easily by indocyanine green(ICG)angiography to predict ischemia related anastomotic complications during laparoscopic colorectal ***,various parameter-based perfusion analysis have been studied for quantitative evaluation,but the analysis results differ depending on the use of quantitative parameters due to differences in vascular anatomical ***,it can help improve the accuracy and consistency by artificial intelligence(AI)based real-time analysis microperfusion(AIRAM).AIM To evaluate the feasibility of AIRAM to predict the risk of anastomotic complication in the patient with laparoscopic colorectal cancer *** The ICG curve was extracted from the region of interest(ROI)set in the ICG fluorescence video of the laparoscopic colorectal ***-processing was performed to reduce AI performance degradation caused by external environment such as background,light source reflection,and camera shaking using MATLAB 2019 on an I7-8700k Intel central processing unit(CPU)*** learning and evaluation were performed by dividing into a training patient group(n=50)and a test patient group(n=15).Training ICG curve data sets were classified and machine learned into 25 ICG curve patterns using a self-organizing map(SOM)*** predictive reliability of anastomotic complications in a trained SOM network is verified using test *** AI-based risk and the conventional quantitative parameters including T1/2max,time ratio(TR),and rising slope(RS)were consistent when colonic perfusion was favorable as steep increasing ICG curve *** the ICG graph pattern showed stepped rise,the accuracy of conventional quantitative parameters decreased,but the AI-based classification maintained accuracy *** receiver operating characteristic curves for conventional parameters and AI-based classification were comparable for predicting the anastomotic complication *** pe

关键词： Indocyanine green Laparoscopic Artificial intelligent Anastomotic complications Colorectal surgery Microcirculation analysis

Small bowel ulcer bleeding due to suspected clopidogrel use in a patient with clopidogrel resistance:A case report

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World Journal of Clinical Cases 2021年第15期9卷 3689-3695页

作者： sang Hoon Lee Dong Ryeol Ryu Sung Joon Lee Sung Chul Park Byung ryul Cho Seung Koo Lee sang Ji Choi Hyun Seok Cho Division of Gastroenterology Department of Internal MedicineKangwon National University HospitalKangwon National University School of MedicineChuncheon-si 24289South Korea Division of Cardiology Department of Internal MedicineKangwon National University HospitalKangwon National University School of MedicineChuncheon-si 24289South Korea Department of Anatomic Pathology Kangwon National University HospitalKangwon National University School of MedicineChuncheon-si 24289South Korea Department of Surgery Kangwon National University HospitalKangwon National University School of MedicineChuncheon-si 24289South Korea Department of Hospital Medicine Kangwon National University HospitalChuncheon-si 24289South Korea

BACKGROUND Clopidogrel is a platelet aggregation inhibitor used for the management of cardiovascular *** antiplatelet therapy decreases cardiovascular events after successful coronary drug-eluting stenting,it increases the risk of gastrointestinal(GI)*** 20%of the patients who take clopidogrel exhibit resistance to the *** SUMMARY We report the first case of a small bowel bleeding ulcer in an 86-year-old man with clopidogrel *** had a history of taking clopidogrel due to unstable *** was no evidence of bleeding in the stomach,duodenum,or colon through upper and lower GI *** abdominal computed tomography showed the extravasation of radiocontrast media at the *** of unstable vital signs,emergency surgery was *** ulcers with inflammation were found in the *** pathologic findings revealed simple *** VerifyNow P2Y12 test showed clopidogrel *** year after changing to aspirin,capsule endoscopy was performed and the small bowel ulcers were *** Small bowel ulcers and bleeding due to clopidogrel are not very common,but the prevalence is expected to increase in older age patients with risk factors despite clopidogrel resistance.

关键词： Clopidogrel Resistance Small bowel Multiple ulcers Hematochezia Surgery Case report

The Impact of Semi-Supervised Learning on the Performance of Intelligent Chatbot System

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Computers, Materials & Continua 2022年第5期71卷 3937-3952页

作者： Sudan Prasad Uprety Seung ryul Jeong The Graduate School of Business Information Technology Kookmin UniversitySeoul02707Korea

Artificial intelligent based dialog systems are getting attention from both business and academic *** key parts for such intelligent chatbot systems are domain classification,intent detection,and named entity *** supervised,unsupervised,and hybrid approaches are used to detect each *** intelligent systems,also called natural language understanding systems analyze user requests in sequential order:domain classification,intent,and entity recognition based on the semantic rules of the classified *** sequential approach propagates the downstream error;i.e.,if the domain classification model fails to classify the domain,intent and entity recognition ***,training such intelligent system necessitates a large number of user-annotated datasets for each *** study proposes a single joint predictive deep neural network framework based on long short-term memory using only a small user-annotated dataset to address these *** investigates value added by incorporating unlabeled data from user chatting logs into multi-domain spoken language understanding *** experimental analysis of the proposed joint frameworks,along with the semi-supervised multi-domain model,using open-source annotated and unannotated utterances shows robust improvement in the predictive performance of the proposed multi-domain intelligent chatbot over a base joint model and joint model based on adversarial learning.

关键词： Chatbot dialog system joint learning LSTM natural language understanding semi-supervised learning

Effect of Ni Contents on the Microstructure and Mechanical Properties of Martensitic Stainless Steel Guide Roll by Centrifugal Casting

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Journal of Materials Science & Technology 2008年第3期24卷 343-346页

作者： Villando Thursdiyanto Eun-Jae Bae Eung-ryul Baek School of Materials Science and Engineering Yeungnam University

A novel process based on centrifugal casting was developed to produce martensitic stainless steel for guideroll materials. Centrifugal casting provides a lower production cost and less of the thermal cracking defects which normally occur in the overlaid welding process. In this study, the effects of Ni on the microstructure and mechanical properties of martensitic stainless steel were investigated. The results show that the addition of Ni resulted in a decrease in the volume fraction of delta ferrite and an increase in the volume fraction of the retained austenite, respectively. Moreover, a tensile strength of 1600 MPa with an elongation of 4% were obtained after tempering at 500℃ for 2 h. These values were higher than those obtained by using the conventional overlaid process.

关键词： Centrifugal casting Martensitic stainless steel Delta ferrite Mechanical properties

Regulation of cell locomotion by nanosecond-laser-induced hydroxyapatite patterning

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Bioactive Materials 2021年第10期6卷 3608-3619页

作者： Seung-Hoon Um Jaehong Lee In-Seok Song Myoung-ryul Ok Yu-Chan Kim Hyung-Seop Han sang-Hoon Rhee Hojeong Jeon Center for Biomaterials Biomedical Research InstituteKorea Institute of Science and Technology(KIST)Seoul02792Republic of Korea Department of Dental Biomaterials Science Dental Research InstituteSchool of DentistrySeoul National UniversitySeoul03080Republic of Korea Department of Oral and Maxillofacial Surgery Korea University Anam HospitalSeoul02841Republic of Korea Division of Bio-Medical Science and Technology KIST SchoolKorea University of Science and TechnologySeoul02792Republic of Korea KU-KIST Graduate School of Converging Science and Technology Korea UniversitySeoul02841Republic of Korea

Hydroxyapatite,an essential mineral in human bones composed mainly of calcium and phosphorus,is widely used to coat bone graft and implant surfaces for enhanced biocompatibility and bone *** a strong implant-bone bond,the bone-forming cells must not only adhere to the implant surface but also move to the surface requiring bone ***,strong adhesion tends to inhibit cell migration on the surface of ***,a cell migration highway pattern that can promote cell migration was prepared using a nanosecond laser on hydroxyapatite *** developed surface promoted bone-forming cell movement compared with the unpatterned hydroxyapatite surface,and the cell adhesion and movement speed could be controlled by adjusting the pattern ***-cell microscopy,cell tracking,and serum protein analysis revealed the fundamental principle of this *** findings are applicable to hydroxyapatite-coated biomaterials and can be implemented easily by laser patterning without complicated *** cell migration highway can promote and control cell movement while maintaining the existing advantages of hydroxyapatite ***,it can be applied to the surface treatment of not only implant materials directly bonded to bone but also various implanted biomaterials implanted that require cell movement control.

关键词： Nanosecond laser Laser engraving Hydroxyapatite patterning Cell migration control Cell tracking