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Widely tunable ultra-narrow-linewidth dissipative soliton generation at the telecom band

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Photonics Research 2020年第7期8卷 1100-1109页

作者： Chang Kyun Ha Ki sang lee Dohyeon Kwon Myeong Soo Kang Department of Physics Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141South Korea School of Mechanical and Aerospace Engineering Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141South Korea

Ultra-narrow-linewidth mode-locked lasers with wide wavelength tunability can be versatile light sources for a variety of newly emergent ***,it is very challenging to achieve the stable mode locking of substantially long,anomalously dispersive fiber laser cavities employing a narrowband spectral filter at the telecom ***,we show that a nearly dispersion-insensitive dissipative mode-locking regime can be accessed through a subtle counterbalance among significantly narrowband spectral filtering,sufficiently deep saturable absorption,and moderately strong in-fiber Kerr *** achieves ultra-narrow-linewidth(a few gigahertz)nearly transform-limited self-starting stable dissipative soliton generation at low repetition rates(a few megahertz)without cavity dispersion management over a broad tuning range of wavelengths covering the entire telecom *** unique laser may have immediate application as an idealized pump source for high-efficiency nonlinear frequency conversion and nonclassical light generation in dispersion-engineered tightly light-confining microphotonic/nanophotonic systems.

关键词： tunable narrow soliton

Parametric study on hydraulic performance of an inlet plenum in a printed-circuit heat exchanger

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Science China(Technological Sciences) 2013年第9期56卷 2137-2142页

作者： lee sang-Moon KOO Gyoung-Wan KIM Kwang-Yong Department of Mechanical Engineering Inha University

Hydraulic performance of an inlet plenum in a printed-circuit heat exchanger has been analyzed using three-dimensional Reynolds-Averaged Navier-Stokes equations. The numerical model of the inlet plenum was constructed through grid dependency test, calculation domain tests, and turbulence model and numerical scheme selections. Shear stress transport turbulence model was used for analysis of turbulence. Non-uniformity of the flow in zigzag flow channels was evaluated for the reference case. Parametric studies have been performed with the angle of the inlet plenum wall, radius of curvature of the inlet plenum wall, and width of the inlet pipes. The effects of these parameters on the flow uniformity and friction performance were evaluated.

关键词： printed-circuit heat exchanger inlet plenum Reynolds-averaged Navier-Stokes equations flow uniformity friction

Spontaneous rupture of adrenal myelolipoma as a cause of acute flank pain:A case report

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World Journal of Clinical Cases 2021年第22期9卷 6552-6556页

作者： Dong Soo Kim Jeong Woo lee sang Hyub lee Department of Urology School of MedicineKyung Hee UniversitySeoul 02447South Korea

BACKGROUND Adrenal myelolipoma is a rare,benign,non-functioning mass that occurs in the adrenal *** is composed of an admixture of hematopoietic elements and mature adipose tissue,similar to bone *** at large sizes,adrenal myelolipomas are usually asymptomatic and often incidentally found by ultrasonography or computed tomography(CT)*** paper describes an unusual case of adrenal myelolipoma presenting as flank *** SUMMARY A 50-year-old male with severe right flank pain underwent a CT scan revealing a huge mass extending into the suprarenal *** mass showed a fat component with retroperitoneal *** tumor was treated laparoscopically,and pathologic examination revealed features of myelolipoma originating from the adrenal *** Adrenal myelolipomas are generally asymptomatic and can be treated ***,rupture and hemorrhage of the tumor can cause symptoms requiring surgical removal.

关键词： Adrenal neoplasms Myelolipoma Adrenal glands Case report

Quality of life for primary caregivers of muscular dystrophy patients in South Korea

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Chinese Medical Journal 2010年第4期123卷 452-457页

作者： sang Hee Im sang Chul lee Jae Ho Moon Eun Sook Park Yoon Ghil Park Department of Rehabilitation Medicine Jeju National University School of Medicine Jeju & Yonsei University Graduate School Seoul Korea Department of Physical Medicine and Rehabilitation Myongji Hospital Kwandong University College of Medicine Goyang Korea Department of Rehabilitation Medicine and Rehabilitation Institute of Muscular Disease Yonsei University College of Medicine Seoul Korea Department and Research Institute of Rehabilitation Medicine Yonsei University College of Medicine Seoul Korea

Background Although some studies measured the burden of caregivers and the factors that influenced their feelings of burden, few studies have measured the quality of life （QOL） for primary caregivers of patients with muscular dystrophy （MD）. We assessed the QOL for primary caregivers of patients with MD in South Korea and identified factors associated with caregivers＇ QOL. Methods Ninety dyads of patients with MD and their primary caregivers were enrolled in this study. The QOL of caregivers of patients with MD was assessed subjectively using the World Health Organization Quality of Life Assessment, Life Brief Form. Caregivers＇ emotional status was assessed using the Beck Depression Inventory （BDI） and family function level was evaluated using the Family APGAR scale. Patients reported their emotional status using the BDI or the Children＇s Depression Inventory. The functional levels of patients were evaluated by the modified Barthel Index. Results Caregivers＇ QOL was statistically associated with family income, family function, emotional status of patients, level of education, and emotional status of caregivers （P 〈0.05）. Caregivers who were employed had a significantly higher QOL than those who were not （P 〈0.05）. In multiple regression analyses, emotional and employment status of caregivers was strongly associated with caregivers＇ QOL. Conclusion Rehabilitation teams should consider not only the physical factors of patients but also the psychological and demographic factors of primary caregivers of patients with MD.

关键词： caregiver quality of life muscular dystrophy

Absorption characteristics of new solvent based on a blend of AMP and 1,8-diamino-p-menthane for CO_2 absorption

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Journal of Environmental Sciences 2012年第5期24卷 897-902页

作者： sang-Sup lee Seong-Man Mun Won-Joon Choi Byoung-Moo Min sang-Won Cho Kwang-Joong Oh Department of Environmental Engineering Chungbuk National University Department of Environmental Engineering Pusan National University Corporate R&D Institute Fuel Cell System Development Team Doosan Heavy Industries & Construction Greenhouse Gas Research Center Korea Institute of Energy Research Department of Energy and Environment Korea Polytechnic VII College

Aqueous 1,8-diamino-p-menthane （KIER-C3） and commercially available amine solutions were tested for CO2 absorption. A 2-amino-2-methyl-1-propanol （AMP） solution with an addition of KIER-C3 showed 9.3% and 31.6% higher absorption rate for CO2 than the AMP solution with an addition of monoethanolamine （MEA） and ammonia （NH3）, respectively. The reaction rate constant for CO2 absorption by the AMP/KIER-C3 solution was determined by the following equation： k2,AMP/C3 = 7.702×106 exp （-2248.03/T）. A CO2 loading ratio of the AMP/KIER-C3 solution was also 2 and 3.4-times higher than that of the AMP/NH3 solution and the AMP/MEA solution, respectively. Based on the experimental results, KIER-C3 may be used as an excellent additive to increase CO2 absorption capability of AMP.

关键词： carbon dioxide absorption rate and capacity 1 8-diamino-p-menthane 2-amino-2-methyl-1-propanol

Dynamics modeling and motion control for high-speed underwater vehicles using H-infinity synthesis with anti-windup compensator

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Journal of Ocean Engineering and Science 2022年第1期7卷 84-91页

作者： Phuc Duc Hong Bui Sam-sang You Hwan-Seong Kim sang-Do lee Department of Mechanical Engineering The University of TulsaTulsaOK 74104United States Division of Mechanical Engineering Korea Maritime and Ocean UniversityBusan 49112Republic of Korea Division of Logistics Engineering Korea Maritime and Ocean UniversityBusan 49112Republic of Korea Division of Navigation and Information System Mokpo National Maritime UniversityMokpoJeollanam-do 58628Republic of Korea

The control synthesis of a high-speed supercavitating vehicle(HSSV)faces many difficulties such as the stability,control,and maneuvering with dynamical uncertainties due to parameter perturbations,exter-nal disturbances,unmodeled dynamics,measurement noises,and actuator *** by the HSSV dynamical analysis,this paper proposes the H∞(i.e."H-infinity")robust control synthesis to gen-erate a robust low-order controller,which is intended for real implementations to ensure active control ***,the presented control scheme includes a feedback component and an anti-windup *** anti-windup synthesis is to provide system stability under actuator ***-tensive simulations show that the designed controller provides good performances with high robustness for vertical plane manoeuver while effectively eliminating planning forces,exogenous disturbances and noises as well as overcoming cavitator saturations.

关键词： Vehicle dynamics Planing force Vertical maneuver H-infinity control Anti-windup Actuator saturation

Temozolomide resistance in glioblastoma multiforme

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Genes & Diseases 2016年第3期3卷 198-210页

作者： sang Y.lee Department of Neurosurgery The Pennsylvania State University College of MedicineHersheyPA 17033USA

Temozolomide(TMZ)is an oral alkylating agent used to treat glioblastoma multiforme(GBM)and ***,at least 50%of TMZ treated patients do not respond to *** is due primarily to the over-expression of O6-methylguanine methyltransferase(MGMT)and/or lack of a DNA repair pathway in GBM *** GBM cell lines are known to contain TMZ resistant cells and several acquired TMZ resistant GBM cell lines have been developed for use in experiments designed to define the mechanism of TMZ resistance and the testing of potential ***,the characteristics of intrinsic and adaptive TMZ resistant GBM cells have not been systemically *** article reviews the characteristics and mechanisms of TMZ resistance in natural and adapted TMZ resistant GBM cell *** also summarizes potential treatment options for TMZ resistant GBMs.

关键词： Adaptive Glioblastoma Intrinsic Resistance Temodar Temozolomide

Treatment of syringomyelia using uncultured umbilical cord mesenchymal stem cells: A case report and review of literature

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World Journal of Stem Cells 2022年第4期14卷 303-309页

作者： Hyunjun Ahn sang Yeon lee Won-Ju Jung Kye-Ho lee Stem Cell Treatment and Research Institute(STRI) bio Beauty and Health Company(bBHC)Seoul 04420South Korea Stem Cell Treatment 97.7 Beauty and Health ClinicSeoul 04420South Korea

BACKGROUND Syringomyelia is a disease caused by the formation of a cavity inside the spinal cord and is accompanied by such symptoms as pain,paresthesia,and urination and defecation disorders,and in severe cases causes various ***,there are only surgical methods for the treatment of syringomyelia,but these methods carry the possibility of failure,recurrence,and side *** SUMMARY The patient was a 59-year-old woman who suffered from pain due to *** treatment,the patient received transplant of uncultured umbilical cord-derived mesenchymal stem *** intended,the patient's pain was relieved after ***,an additional benefit was found in that the size of the cavity also *** 2 years from the last treatment,the patient's cavity had almost completely disappeared and her syringomyelia was deemed *** Using uncultured umbilical cord-derived mesenchymal stem cells may be a new treatment alternative for syringomyelia.

关键词： Syringomyelia Umbilical cord mesenchymal stem cells Cell therapy Allogenic stem cells Chiari malformations Case report

Interleukin-2 gene-encoded stromal cells inhibit the growth of metastatic cholangiocarcinomas

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World Journal of Gastroenterology 2006年第12期12卷 1889-1894页

作者： Myung-HwanKim sang Soo lee Sung Koo lee Seung-Gyu lee Chul-Won Suh Gyung-Yub Gong Jung-Sun Park Young-Hoon Kim sang-Hee Kim Department of Gastroenterology University of Ulsan College of MedicineAsan Medical CenterSeoulKorea Department of Surgery University of Ulsan College of MedicineAsan Medical CenterSeoulKorea Department of Oncology University of Ulsan College of MedicineAsan Medical CenterSeoul Korea Department of Pathology University of Ulsan College of MedicineAsan Medical CenterSeoulKorea Asan Institute for Life Sciences.Seoul Korea

AIM： To demonstrate bone marrow stromal cells （BMSCs） can be used as an attractive target for genetic modification in the treatment of malignant diseases. METHODS： Using a hamster model of biliary cancer, we investigated the therapeutic effects of interleukin-2 （IL-2） gene-modified BHSCs. Syrian golden hamsters were injected via the femoral vein with 5×10^5 cells of the KIGB-5 biliary cancer cell line （n=20）. One week later, the hamsters were injected intraperitoneally with BMSCs containing Ad/hIL-2 and Ad/△E1, unmodified BHSCs, or RPHI only （control） and observed for 12 wk （n=5/each group）. RESULTS： All hamsters treated with BMSCs containing Ad/hIL-2 survived with no evidence of the disease during this period. In contrast, hamsters in the other three groups showed disseminated metastases involving the lungs as eady as 4 wk.CONCLUSION： Ad/IL-2 therapy is effective in the treatment of biliary cancer.

关键词： Bone marrow stromal cell Adenovirus/hIL-2 Biliary cancer