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Usefulness of magnifying endoscopy in post-endoscopic resection scar for early gastric neoplasm:A prospective short-term follow-up endoscopy study

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World Journal of Gastroenterology 2009年第3期15卷 349-355页

作者： Tae Hoon Lee Il-Kwun Chung Ji-Young Park Chang Kyun Lee Suck-Ho Lee Hong Soo Kim sang-Heum Park Sun-Joo Kim hyun-Deuk cho Young Hwangbo Division of Gastroenterology Department of Internal MedicineSoonchunhyang University College of MedicineCheonan Hospital23-20 Bongmyung-dongCheonan330-721South Korea Department of Pathology Soonchunhyang University College of MedicineCheonan Hospital23-20 Bongmyung-dongCheonan330-721South Korea Department of Preventive Medicine Soonchunhyang University College of MedicineCheonan Hospital23-20 Bongmyung-dongCheonan330-721South Korea

AIM： To investigate the relationship between postendoscopic resection （ER） scars on magnifying endoscopy （ME） and the pathological diagnosis in order to validate the clinical significance of ME. METHODS： From January, 2007 to June, 2008, 124 patients with 129 post-ER scar lesions were enrolled. Mucosal pit patterns on ME were compared with conventional endoscopy （CE） findings and histological results obtained from targeted biopsies. RESULTS： CE findings showed nodular scars （53/129）, erythematous scars （85/129）, and ulcerative scars （4/129）. The post-ER scars were classified into four pit patterns of sulci and ridges on ME：（ Ⅰ ） 47 round; （Ⅱ） 54 short rod or tubular; （Ⅲ） 19 branched or gyrus-like;and （Ⅳ） 9 destroyed pits. Sensitivity and specificity were 88.9% and 62.5%, respectively, by the presence of nodularity on CE. Erythematous lesions were high sensitivity （100%）, but specificity was as low as 36.7%. The range of the positive predictive va ue （PPV） on CE was as low as 10.6%-25%. Nine type N pit patterns were diagnosed as tumor lesions, and 120 cases of type Ⅰ-Ⅲ pit patterns revealed non-neoplastic lesions. Thus, the sensitivity, specificity, and the PPV of ME were 100%. CONCLUSION： ME findings can detect the presence of tumor in post-ER scar lesions, and make evident the biopsy target site in short-term follow-up. Further large-scale and long-term studies are needed to determine whether ME can replace endoscopic biopsy.

关键词： Endoscopic mucosal resection Endoscopic submucosal dissection Magnifying endoscopy Pitpattern Scar

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New botanical drug, HL tablet, reduces hepatic fat as measured by magnetic resonance spectroscopy in patients with nonalcoholic fatty liver disease: A placebo-controlled, randomized, phase Ⅱ trial

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World Journal of Gastroenterology 2017年第32期23卷 5977-5985页

作者： Jae Yoon Jeong Joo hyun Sohn Yang hyun Baek Yong Kyun cho Yongsoo Kim Hyeonjin Kim Department of Internal Medicine Hanyang University Guri HospitalHanyang University College of Medicine Department of Internal Medicine Dong-A University HospitalDong-A University College of Medicine Department of Internal Medicine Kangbuk Samsung HospitalSungkyunkwan University School of Medicine Department of Radiology Hanyang University Guri HospitalHanyang University College of Medicine Department of Radiology Seoul National University Hospital

AIM To evaluate the efficacy and safety of HL tablet extracted from magnolia officinalis for treating patients with nonalcoholic fatty liver disease(NAFLD).METHODS Seventy-four patients with NAFLD diagnosed by ultrasonography were randomly assigned to 3 groups given high dose(400 mg) HL tablet, low dose(133.4 mg) HL tablet and placebo, respectively, daily for 12 wk. The primary endpoint was post-treatment change of hepatic fat content(HFC) measured by magnetic resonance spectroscopy. Secondary endpoints included changes of serum aspartate aminotransferase, alanine aminotransferase(ALT), cholesterol, triglyceride, free fatty acid, homeostasis model assessment-estimated insulin resistance, and body mass index(BMI).RESULTS The mean HFC of the high dose HL group, but not of the low dose group, declined significantly after 12 wk of treatment(high dose vs placebo, P = 0.033; low dose vs placebo, P = 0.386). The mean changes of HFC from baseline at week 12 were-1.7% ± 3.1% in the high dose group(P = 0.018),-1.21% ± 4.97% in the low dose group(P = 0.254) and 0.61% ± 3.87% in the placebo group(relative changes compared to baseline, high dose were:-12.1% ± 23.5%, low dose:-3.2% ± 32.0%, and placebo: 7.6% ± 44.0%). Serum ALT levels also tended to decrease in the groups receiving HL tablet while other factors were unaffected. There were no moderate or severe treatment-related safety issues during the *** HL tablet is effective in reducing HFC without any negative lipid profiles, BMI changes and adverse effects.

关键词： Botanical drug Nonalcoholic fatty liver disease Magnetic resonance spectroscopy Randomized controlled trial Magnolia officinali

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Characteristics of Micro Electrochemical Polishing to Improve the Surface Quality of the Stainless Steel Tube

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Journal of Iron and Steel Research International 2012年第S2期19卷 1137-1140页

作者： Seung-Gun choi Sung-hyun Kim Eun-sang Lee Seung-Bok choi Myeong-woo cho School of Mechanical Engineering Inha University Department of Mechanical Engineering Inha University

Electrochemical polishing is the anodic dissolution process without contact with tools,is a surface treatment method to make a surface planarization using an electrochemical reaction with low applied *** surface quality is mainly affected by the many process *** improve the surface quality,the control of parameters is very *** aim of this study is to investigate the characteristic of electrochemical polishing effect for inner diameter of Stainless Steel *** order to analyze the characteristics of surface quality were measured in terms of temperature, applied current and machining *** investigation can enhance the surface quality of inner diameter Stainless Steel ***,we have verified improved results by using selected optimal conditions.

关键词： Electrochemical polishing surface quality applied current

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Prognostics and health management of alkaline water electrolyzer: Techno-economic analysis considering replacement moment

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Energy and AI 2023年第3期13卷 160-168页

作者： hyunjun Lee Jiwon Gu Boreum Lee hyun-Seok cho Hankwon Lim School of Energy and Chemical Engineering Ulsan National Institute of Science and Technology50 UNIST-gilEonyang-eupUlju-gunUlsan 44919Republic of Korea Hydrogen Research Department Future Energy Research DivisionKorea Institute of Energy Research152 Gajeong-roYuseongDaejeonRepublic of Korea Graduate School of Carbon Neutrality Ulsan National Institute of Science and Technology50 UNIST-gilEonyang-eupUlju-gunUlsan 44919Republic of Korea Carbon Neutrality Demonstration and Research Center Ulsan National Institute of Science and Technology50 UNIST-gilEonyang-eupUlju-gunUlsan 44919Republic of Korea

Recently,considerable attention has been paid to the installation of renewable energy capacity to mitigate global CO_(2) emissions.H_(2) produced using water electrolysis and renewable energy is regarded as a clean energy carrier,generating electricity without CO_(2) emissions,called‘Green H 2’.In this paper,a prognostics and health man-agement model for an alkaline water electrolyzer was proposed to predict the load voltage on the electrolyzer to obtain the state of health *** prognostics and health management model was developed by training historical operating data via machine learning models,support vector machine and gaussian process regression,showing the root mean square error of 1.28×10^(−3) and 8.03×10^(−6).In addition,a techno-economic analysis was performed for a green H_(2) production system,composed of 1 MW of photovoltaic plant and 1 MW of alkaline water electrolyzer,to provide economic insights and feasibility of the system.A levelized cost of H_(2) of$6.89 kgH_(2)−1 was calculated and the potential to reach the levelized cost of H_(2) from steam methane reforming with carbon capture and storage was shown by considering the learning rate of the photovoltaic module and ***,the replacement of the alkaline water electrolyzer at around 10 years was preferred to increase the net present value from the green H_(2) production system when capital expenditure and replacement cost are low enough.

关键词： Green H_(2) Alkaline water electrolysis Prognostics and health management Voltage degradation Techno-economic analysis Replacement

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Bilateral snapping triceps syndrome:A case report

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World Journal of Clinical Cases 2023年第34期11卷 8228-8234页

作者： Chul-hyun cho Kyung-Hwan Lim Du-Han Kim Department of Orthopedic Surgery Keimyung University Dongsan HospitalKeimyung University School of MedicineDaegu 42601South Korea Orthopedic Surgery Allright HospitalDaegu 42038South Korea

BACKGROUND Snapping triceps syndrome(STS)is a rare disease,while occurrence of bilateral STS is extremely *** is usually accompanied by dislocation of the ulnar nerve and double snapping is a clinically important ***,to the best of our knowledge,there has been no report of bilateral STS in young active *** SUMMARY A 23-year-old male presented with a complaint of discomfort and snapping on the medial side of both elbows while performing *** physical examination,two distinct snaps that were both palpable and audible were detected on additional clinical *** ultrasonography showed that the ulnar nerve and the medial head of the triceps were dislocated anteriorly over the medial epicondyle of the elbow during flexion ***,he was diagnosed as dislocation of the ulnar nerve and *** anterior subcutaneous transposition of the ulnar nerve combined with partial resection of the snapping portion of the triceps was *** patient’s pain and snapping symptoms were resolved immediately after *** months later,the patient was completely asymptomatic and returned to normal *** STS should be included in the differential diagnosis for active young patients who present with painful snapping on the medial side of the elbow joint,particularly when dislocation of the ulnar nerve is *** sonography is used to assist in accurate diagnosis and differentiation between isolated dislocation of the ulnar nerve and STS.

关键词： Triceps Triceps snapping syndrome Ulnar nerve Elbow Dynamic sonography Case report

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Bilateral dislocation of the long head of biceps tendon with intact rotator cuff tendon:A case report

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世界临床病例杂志 2023年第26期11卷 6304-6310页

作者： Hyuk-Joon Sohn Chul-hyun cho Du-Han Kim Department of Orthopedic Surgery Keimyung University Dongsan HospitalKeimyung University School of MedicineDaegu 42601South Korea

BACKGROUND Dislocation of the long head of biceps tendon(LHBT)usually involves rotator cuff injury,and isolated dislocation with an intact rotator cuff is *** cases of isolated dislocation have been ***,to the best of our knowledge,there has been no report of bilateral dislocation of the LHBT without rotator cuff *** SUMMARY A 23-year-old male presented to our outpatient clinic with left side dominant pain in both *** patient had no history of trauma or *** patient underwent intra-articular injection and physical therapy,but his symptoms *** on preoperative imaging,the diagnosis was bilateral dislocation of the *** of the bicipital groove was detected in both *** dislocation of the biceps tendon over an intact subscapularis tendon was identified by diagnostic *** biceps tenodesis was performed and continuous passive motion therapy was administered immediately after *** patient’s pain was resolved,and full functional recovery was achieved,and he was satisfied with the condition of his *** This study describes a rare case of bilateral dislocations of the LHBT without rotator cuff injury due to dysplasia of the bicipital groove.

关键词： Shoulder Biceps Dislocation Rotator cuff Tenodesis Case report

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外部静水压力作用下完好和损伤环肋圆柱壳极限强度计算公式

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中国舰船研究 2019年第S2期14卷 23-31页

作者： Do Quang Thang Park sang hyun cho sang Rai 芽庄大学造船与海洋工程学系越南芽庄650000 蔚山大学造船与海洋工程学院韩国蔚山44610

[目的]重点推导在静水压力下完好和损伤的钢质环肋圆柱壳极限强度预测公式。考虑的损伤场景可代表海上环肋圆柱壳结构(如潜艇、半潜式平台、桅杆以及作为浮式海上风力涡轮机底座的浮柱)的碰撞事故。[方法]验证数值模拟和分析技术,对6种... 详细信息

[目的]重点推导在静水压力下完好和损伤的钢质环肋圆柱壳极限强度预测公式。考虑的损伤场景可代表海上环肋圆柱壳结构(如潜艇、半潜式平台、桅杆以及作为浮式海上风力涡轮机底座的浮柱)的碰撞事故。[方法]验证数值模拟和分析技术,对6种小型环肋圆柱壳模型进行试验。首先,采用刀口压头跌落试验分析4种圆柱模型的损坏情况,然后将所有模型置于静水压力下进行测试,以评估完好和损坏情况下的极限强度。通过改变设计变量,对实际设计的全尺寸环肋圆柱壳进行严格的参数化研究,最后根据参数化研究结果推导出预测损坏环肋圆柱壳剩余强度的简单计算公式。[结果]计算结果与试验结果和有限元分析结果的准确性和可靠性比较结果显示,在所有载荷情况下,吻合均较好。[结论]所做研究对海上结构物环肋圆柱壳的设计和使用极限状态评估具有一定的参考价值。

关键词：损伤环肋圆柱壳碰撞试验剩余强度试验数值模拟设计公式

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Discriminating between explosions and earthquakes

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Applied Geophysics 2014年第4期11卷 429-436,509,510页

作者： cho Kwang-hyun Petroleum Technology Institute Korea National Oil Corporation

Earthquake, explosion, and a nuclear test data are compared with forward modeling and band-pass filtered surface wave amplitude data for exploring methodologies to improve earthquake–explosion discrimination. The proposed discrimination method is based on the solutions of a double integral transformation in the wavenumber and frequency domains. Recorded explosion data on June 26, 2001（39.212°N, 125.383°E） and October 30, 2001（38.748°N, 125.267°E）, a nuclear test on October 9, 2006（41.275°N, 129.095°E）, and two earthquakes on April 14, 2002（39.207°N, 125.686°E） and June 7, 2002（38.703°N, 125.638°E）, all in North Korea, are used to discriminate between explosions and earthquakes by seismic wave analysis and numerical modeling. The explosion signal is characterized by first P waves with higher energy than that of S waves. Rg waves are clearly dominant at 0.05–0.5 Hz in the explosion data but not in the earthquake data. This feature is attributed to the dominant P waves in the explosion and their coupling with the SH components.

关键词： explosion earthquake nuclear test P wave Rg wave numerical modeling

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Comparison of linac-based fractionated stereotactic radiotherapy and tomotherapy treatment plans for intra-cranial tumors

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Chinese Physics C 2010年第11期34卷 1768-1774页

作者： Jang Bo Shim Suk Lee Sam Ju cho sang Hoon Lee Juree Kim Kwang Hwan cho Chul Kee Min hyun Do Huh Rena Lee Dae Sik Yang Young Je Park Won Seob Yoon Chul Yong Kim Soo Il Kwon Department of Radiation Oncology College of MedicineKorea University Department of Medical Physics Kyonggi University Department of Radiation Oncology College of MedicineEulji University Department of Radiation Oncology Cheil General Hospital & Women's Healthcare CenterKwandong University College of Medicine Department of Radiation Oncology Soonchunhyang University Boocheon Hospital Department of Radiation Oncology Konyang University Hospital Department of Radiation Oncology Inha University Hospital Department of Radiation Oncology School of MedicineEwha Womans University

This study compares and analyzes stereotactic radiotherapy using tomotherapy and linac-based fractionated stereotactic radiotherapy in the treatment of intra-cranial tumors,according to some *** this study,linac-based fractionated stereotactic radiotherapy and tomotherapy treatment were administered to five patients diagnosed with intra-cranial cancer in which the dose of 18–20 Gy was applied on 3–5 separate *** tumor dosing was decided by evaluating the inhomogeneous index （II） and conformity index （CI）.Also,the radiation-sensitive tissue was evaluated using low dose factors V1,V2,V3,V4,V5,and V10,as well as the non-irradiation ratio volume （NIV）.The values of the II for each prescription dose in the linacbased non-coplanar radiotherapy plan and tomotherapy treatment plan were （0.125±0.113） and （0.090±0.180）,respectively,and the values of the CI were （0.899±0.149） and （0.917±0.114）,*** low dose areas,V1,V2,V3,V4,V5,and V10,in radiation-sensitive tissues in the linac-based non-coplanar radiotherapy plan fell into the ranges 0.3%–95.6%,0.1%–87.6%,0.1%–78.8%,38.8%–69.9%,26.6%–65.2%,and 4.2%–39.7%,respectively,and the tomotherapy treatment plan had ranges of 13.6%–100%,3.5%–100%,0.4%–94.9%,0.2%– 82.2%,0.1%–78.5%,and 0.3%–46.3%,*** the NIV for each organ,it is possible to obtain similar values except for the irradiation area of the brain *** percentages of NIV10%,NIV20%,and NIV30%for the brain stem in each patient were 15%–99.8%,33.4%–100%,and 39.8%–100%,respectively,in the fractionated stereotactic treatment plan and 44.2%–96.5%,77.7%–99.8%,and 87.8%–100%,respectively,in the tomotherapy treatment *** order to achieve higher-quality treatment of intra-cranial tumors,treatment plans should be tailored according to the isodose target volume,inhomogeneous index,conformity index,position of the tumor upon fractionated stereotactic radiosurgery,and radiation dosage for radiation-sensitive tissues.

关键词： fractionated stereotactic radiotherapy tomotherapy treatment plan virtual organ delineation

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Suppression of DRR1 results in the accumulation of insoluble ubiquitinated proteins,which impairs drought stress tolerance

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Journal of Integrative Plant Biology 2021年第3期63卷 431-437页

作者： Seong Gwan Yu Na hyun cho Jong Hum Kim Tae Rin Oh Woo Taek Kim Department of Systems Biology and Division of Life Science Yonsei UniversitySeoul 03722Korea Institute of Life Science and Biotechnology Yonsei UniversitySeoul 03722Korea

Drought stress has detrimental effects on *** the abscisic acid(ABA)-mediated drought response is well established,defensive mechanisms to cope with dehydration-induced proteotoxicity have been rarely ***1 was identified as an Arabidopsis drought-induced gene encoding an ER-localized RING-type E3 Ub *** of DRR1 markedly reduced tolerance to drought and proteotoxic stress without altering ABA-mediated germination and stomatal *** dehydration-induced insoluble ubiquitinated protein accumulation was more obvious in DRR1 loss-of-function plants than in wild-type *** results suggest that DRR1 is involved in an ABA-independent drought stress response possibly through the mitigation of dehydration-induced proteotoxic stress.

关键词： Arabidopsis drought stress E3 ligase proteotoxicity ubiquitination

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