检索结果-南通市图书馆

Safety and efficacy of sofosbuvir/velpatasvir/voxilaprevir in postliver transplant patients with previous direct-acting antiviral failure:Six case reports

引用

World Journal of Hepatology 2020年第12期12卷 1341-1348页

作者： Cory Higley Christine C Hsu Coleman Smith sandeep nadella Alexander T.Lalos Department of Medicine MedStar Georgetown University HospitalWashingtonDC 20007United States Transplant Institute MedStar Georgetown University HospitalWashingtonDC 20007United States Department of Gastroenterology Medstar Georgetown University HospitalWashingtonDC 20007United States

BACKGROUND Direct-acting antiviral(DAA)therapy regimens are highly effective at eliminating hepatitis C virus(HCV)infection but rates of sustained virologic response(SVR)are lower in patients with decompensated cirrhosis or hepatocellular *** many of these patients will be referred for liver transplant,they will require retreatment after ***/velpatasvir/voxilaprevir(SOF/VEL/VOX)is recommended by guidelines as the preferred regimen to treat HCV in DAA-experienced patients following liver transplant however there is limited *** SUMMARY We present the cases of six liver transplant recipients who had previous treatment failure with sofosbuvir-based DAA therapy prior to transplantation and who then received SOF/VEL/VOX after *** This case series demonstrate the real-world efficacy and safety of SOF/VEL/VOX in the post liver transplant *** was successful with all patients achieving SVR,it was well tolerated,and there were minimal drug-drug interactions with their immunosuppressants.

关键词： Sofosbuvir/velpatasvir/voxilaprevir Hepatitis C Liver transplant Directacting antiviral Drug-drug interactions Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Role of colonoscopy in diagnosis of capecitabine associated ileitis:Two case reports

引用

World Journal of Gastrointestinal Endoscopy 2019年第5期11卷 383-388页

作者： Alexander E Dao Angela Hsu Ahmad Nakshabandi Rohan Mandaliya sandeep nadella Anita Sivaraman Mark Mattar Aline Charabaty Department of Gastroenterology Medstar Georgetown University Hospital Department of Gastroenterology Johns Hopkins University at Sibley Memorial Hospital

BACKGROUND Capecitabine is considered a first line agent in adjuvant therapy for breast and colorectal cancer. However,cases of severe diarrhea have been reported with increasing frequency in recent years. When diarrhea is severe and prolonged,capecitabine associated ileitis should be considered as a possible *** SUMMARY Herein,we present two cases of capecitabine ileitis,specifically involving the terminal ileum and ascending colon. We will demonstrate the disease course and treatment modalities applied to alleviate this condition,as well as discuss the merits of using colonoscopy to aid in *** Ultimately our cases demonstrate that symptomatic management with traditional anti-diarrheal medications is largely ineffective. Prompt recognition and discontinuation of capecitabine is an imperative step in proper management of this condition and colonoscopy with biopsy can be helpful when the diagnosis is unclear.

关键词： Capecitabine Xeloda 5-Fluorouracil Ileitis Ileocolitis Colonoscopy Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：