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高频低造型电源变压器的设计与应用

电源世界 2001年第9期 19-26页

作者：胡跃全何多慧金泰义 ki-Wai Cheng Yim-Shu Lee 中国科学技术大学精密机械与仪器系合肥230026 香港理工大学电子工程与资讯系

本文探讨了高频低造型电源变压器设计的有关问题,给出了平板式绕组的设计制作方法。该方法能自动串连绕组各层导体,从而解决了绕组各层导体之间的连线问题,避免了焊接,大大提高了器件的可靠性和绕组对磁芯窗口的利用率。实验结果表明,... 详细信息

本文探讨了高频低造型电源变压器设计的有关问题,给出了平板式绕组的设计制作方法。该方法能自动串连绕组各层导体,从而解决了绕组各层导体之间的连线问题,避免了焊接,大大提高了器件的可靠性和绕组对磁芯窗口的利用率。实验结果表明,用这种方法制作的变压器漏感小、效率高,特别适合用于分布式高功率密度的开关电源模块中。文中还给出了高频低造型电源变压器的计算机辅助设计,这不仅使得设计过程更灵活、快捷,也使得设计结果更可靠。

关键词：高频低造型变压器绕组制作计算机辅助设计

极低出生体重早产儿脑室内出血与出生时低凝血因子II活性间的相关性

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世界核心医学期刊文摘（儿科学分册） 2005年第11期1卷 17-17页

作者： SalonvaaraM. Riikonen P. Kekomki R. 朱新菊 Department of Paediatrics KuopioUniversity Hospital PO Box 1777 FIN-70 211 Kuopio Finland

Aim: To determine the occurrence of intraventricular haemorrhage (IVH) and its association with coagulation factors at birth in preterm neonates born before 30 wk gestation. Methods: 38 neonates (median gestational age 27 wk, range 24-29 wk; median birthweight (BW) 933 g, range 515-1760 g) admitted to the neonatal intensive care unit were studied. Blood samples for coagulation factors were taken within 2 h after birth. The first cranial ultrasonographic examination was performed within the first 3 d. The occurrence of IVH was tested statistically by the Mann-Whitney U-test for association with the activity of coagulation factors and clinical variables. Results: Thirteen IVHs occurred within the first 3 d of life. IVH was associated with BW <1000 g (p = 0.012), low mean blood pressure within the first 2 d (p = 0.026), gestational age <27 wk (p = 0.054), low Apgar scores (<7) at 1 min (p = 0.078) and intrauterine growth restriction (p = 0.072). At birth (samples drawn with a median of first 36 min of life), infants with subsequent IVH had statistically significantly lower prothrombin (factor II) activity (p = 0.024) than infants without IVH. Conclusion: The measured low prothrombin may have been affected by a prior bleeding event. Nevertheless, preterm infants with low prothrombin activity may be susceptible to IVH, or to the progression of it, if left undiagnosed.

关键词：脑室内出血凝血因子早产新生儿颅脑超声检查生时新生儿病阿氏评分平均血压出生后重症监护

胺碘酮联合稳心颗粒治疗新发心房纤颤的临床体会

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临床合理用药杂志 2014年第27期7卷 15-15,19页

作者：李晓渝安徽省六安市人民医院心血管内科 237005

目的探讨胺碘酮联合稳心颗粒治疗新发心房纤颤的临床疗效。方法选取2010年4月—2014年3月于本院接受治疗的新发心房纤颤患者46例作为研究对象。将其分成对照组及观察组,各23例。对照组给予盐酸胺碘酮联合维拉帕米治疗;观察组给予胺碘酮... 详细信息

目的探讨胺碘酮联合稳心颗粒治疗新发心房纤颤的临床疗效。方法选取2010年4月—2014年3月于本院接受治疗的新发心房纤颤患者46例作为研究对象。将其分成对照组及观察组,各23例。对照组给予盐酸胺碘酮联合维拉帕米治疗;观察组给予胺碘酮及稳心颗粒的联合治疗。比较两组患者的临床疗效。结果观察组临床治疗的总有效率高于对照组,差异有统计学意义(P<0.05)。结论胺碘酮联合稳心颗粒治疗新发心房纤颤,不仅临床治疗疗效显著,而且对患者的身体素质以及生存质量具有提升作用。

关键词：胺碘酮药物疗法,联合心房颤动治疗结果

Management of granulomatous lobular mastitis: an international multidisciplinary consensus(2021 edition)

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Military Medical Research 2022年第4期9卷 389-403页

作者： Qian-Qian Yuan Shu-Yuan Xiao Omar Farouk Yu-Tang Du Fereshte Sheybani Qing Ting Tan sami Akbulut Kenan Cetin Afsaneh Alikhassi Rami Jalal Yaghan Irmak Durur-Subasi Fatih Altintoprak Tae Ik Eom Fatih Alper Mustafa Hasbahceci David Martínez-Ramos Pelin Seher Oztekin Ava Kwong Cedric W.Pluguez-Turul kirstyn EBrownson Shirish Chandanwale Mehran Habib Liu-Yi Lan Rui Zhou Xian-Tao Zeng Jiao Bai Jun-Wen Bai Qiong-Rong Chen Xing Chen Xiao-Ming Zha Wen-Jie Dai Zhi-Jun Dai Qin-Yu Feng Qing-Jun Gao Run-Fang Gao Bao-San Han Jin-Xuan Hou Wei Hou Hai-Ying Liao Hong Luo Zheng-Ren Liu Jing-Hua Lu Bin Luo Xiao-Peng Ma Jun Qian Jian-Yong Qin Wei Wei Gang Wei Li-Ying Xu Hui-Chao Xue Hua-Wei Yang Wei-Ge Yang Chao-Jie Zhang Fan Zhang Guan-Xin Zhang Shao-Kun Zhang Shu-Qun Zhang Ye-Qiang Zhang Yue-Peng Zhang Sheng-Chu Zhang Dai-Wei Zhao Xiang-Min Zheng Le-Wei Zheng Gao-Ran Xu Wen-Bo Zhou Gao-Song Wu Department of Thyroid and Breast Surgery Zhongnan Hospital of Wuhan UniversityWuhan430071China Department of Pathology University of Chicago Pritzker School of MedicineChicagoIL60637USA Department of Surgical Oncology and Breast Surgery Oncology CenterFaculty of MedicineMansoura UniversityMansoura35516Egypt Department of Breast Surgery Beijing University of Chinese MedicineBeijing100700China Department of Infectious Diseases and Tropical Medicine Faculty of MedicineMashhad University of Medical SciencesMashhad***Iran Breast Department KK Women’s and Children’s Hospital100 Bukit Timah RoadSingapore229899Singapore Department of Surgery Department of Public HealthDepartment of BiostatisticsBioinformatics and Medical InformaticsInonu University Faculty of Medicine44280MalatyaTurkey Department of General Surgery Faculty of MedicineÇanakkale Onsekiz Mart University17020ÇanakkaleTurkey Department of Radiology Cancer InstituteImam Khomeini HospitalTehran University of Medical SciencesTehran***Iran Department of Surgery College of Medicine and Medical SciencesArabian Gulf University-BahrainManama26671Bahrain Department of Radiology International Faculty of MedicineIstanbul Medipol University34810IstanbulTurkey Department of General Surgery Faculty of MedicineSakarya University54050SakaryaTurkey Department of Surgery HiU Clinic170Gwongwang-roPaldal-guSuwon16488Korea Department of Radiology Faculty of MedicineAtaturk University25240ErzurumTurkey Academic Support and Education Center Hırkai Serif DistrictKececi Cesmesi StrDoktorlar BuildingB/734091IstanbulTurkey Department of General and Digestive Surgery Hospital General CastellonAvda Benicassim S/N12812004CastellónSpain Radiology Department Ankara Training and Research Hospital305018AnkaraTurkey Department of Surgery The University of Hong KongChina The University of Hong Kong-Shenzhen Hospital Shenzhen518053China University of Miami Health System and Miller School of Medicine 1475 NW 12th AvenueM

Granulomatous lobular mastitis(GLM) is a rare and chronic benign inflammatory disease of the breast. Difficulties exist in the management of GLM for many front-line surgeons and medical specialists who care for patients with inflammatory disorders of the breast. This consensus is summarized to establish evidence-based recommendations for the management of GLM. Literature was reviewed using PubMed from January 1, 1971 to July 31, 2020. Sixty-six international experienced multidisciplinary experts from 11 countries or regions were invited to review the *** of evidence were determined using the American College of Physicians grading system, and recommendations were discussed until consensus. Experts discussed and concluded 30 recommendations on historical definitions,etiology and predisposing factors, diagnosis criteria, treatment, clinical stages, relapse and recurrence of GLM. GLM was recommended as a widely accepted definition. In addition, this consensus introduced a new clinical stages and management algorithm for GLM to provide individual treatment strategies. In conclusion, diagnosis of GLM depends on a combination of history, clinical manifestations, imaging examinations, laboratory examinations and *** approach to treatment of GLM should be applied according to the different clinical stage of GLM. This evidencebased consensus would be valuable to assist front-line surgeons and medical specialists in the optimal management of GLM.

关键词： Granulomatous mastitis Granulomatous lobular mastitis Idiopathic granulomatous mastitis Diagnosis Treatment

来自一项艾日布林联合吉西他滨对比紫杉醇联合吉西他滨作为HER2阴性转移性乳腺癌的一线化疗的Ⅱ期、多中心、随机试验的包含神经病变相关量表的生活质量结果：韩国癌症研究组试验(KCSG BR13-11)

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癌症 2019年第8期38卷 368-376页

作者： Ji‑Yeon kim Seri Park Seock‑Ah Im Sung‑Bae kim Joohyuk Sohn Keun Seok Lee Yee Soo Chae ki Hyeong Lee Jee Hyun kim Young‑Hyuck Im Tae‑Yong kim Kyung‑Hun Lee Jin‑Hee Ahn Gun Min kim In Hae Park Soo Jung Lee Hye Sook Han Se Hyun kim Kyung Hae Jung Yeon Hee Park Korean Cancer Study Group Division of Hematology‑Oncology Department of MedicineSamsung Medical CenterSungkyunkwan University School of Medicine81 Irwon‑roGangnam‑guSeoul 06351South Korea Department of Health Sciences and Technology Samsung Advanced Institute for Health Sciences and TechnologySungkyunkwan UniversitySeoul 06351South Korea Department of Internal Medicine Seoul National University HospitalCancer Research InstituteCollege of MedicineSeoul National UniversitySeoul 03080South Korea Department of Oncology Asan Medical CenterUniversity of Ulsan College of MedicineSeoul 05505South Korea Division of Medical Oncology Department of Internal MedicineYonsei University College of MedicineSeoul 03722South Korea Center for Breast Cancer National Cancer CenterGoyang 10408South Korea Department of Internal Medicine Kyungpook National University HospitalDaegu 41944South Korea Deparment of Internal Medicine Chungbuk National University HospitalCheongju 28644South Korea Department of Internal Medicine Seoul National University Bundang HospitalSeoul National University College of MedicineSeongnam 13620South Korea 不详

背景与目的一项比较艾日布林联合吉西他滨(eribulin plus gemcitabine,EG)或紫杉醇联合吉西他滨(paclitaxel plus gemcitabine,PG)作为转移性乳腺癌(metastatic breast cancer,MBC)患者一线化疗方案的II期临床试验发现,EG方案的神经毒性较低,但疗效与PG方案相似。在本研究中,我们分析了该临床实验中的癌症患者生命质量测评量表–紫杉烷(functional assessment of cancer therapy-taxane,FACT-Taxane)问卷评分以确定他们的生活质量(quality of life,QoL)。方法使用韩国版的FACT-Taxane问卷评估QoL。在评估基线之后,前12个疗程中每2个疗程评估1次QoL,之后每3个疗程评估1次QoL。使用线性混合模型评估EG组和PG组QoL的差异。结果在118例入组患者中,117例在基线时回复了FACT-Taxane问卷,PG组中有1例患者没有回复。EG组和PG组之间的基线QoL评分没有差异。在治疗期间,除了第11个疗程外,在第2–13个化疗疗程后,PG组紫杉烷亚量表评分显著高于EG组(均P<0.05)。神经病变特异性分析显示PG组患者的神经病症状比EG组患者更早出现且更严重(P<0.001)。结论在我们的QoL分析中,与PG方案相比,EG方案延迟并减少神经病变的发生。因此,艾日布林是MBC一线化疗药物紫杉醇的合理替代品。

关键词：转移性乳腺癌艾日布林紫杉醇神经病生活质量癌症患者生命质量测评量表–紫杉烷问卷

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林毅防治乳腺癌复发转移的思路

广州中医药大学学报 2020年第2期37卷 354-357页

作者：司徒红林井含光文灼彬刘畅林毅广东省中医院

整理和归纳林毅教授临床防治乳腺癌复发转移的思路与方法。林毅教授认为乳腺癌复发转移的病机为正气亏虚,余毒未清,痰瘀内阻,毒瘀互结。其中正气亏虚为先决条件,余毒未清是关键因素,痰瘀内阻、毒瘀互结为主要病因。针对其病机的临床治... 详细信息

整理和归纳林毅教授临床防治乳腺癌复发转移的思路与方法。林毅教授认为乳腺癌复发转移的病机为正气亏虚,余毒未清,痰瘀内阻,毒瘀互结。其中正气亏虚为先决条件,余毒未清是关键因素,痰瘀内阻、毒瘀互结为主要病因。针对其病机的临床治疗原则应为"时时扶正,适时祛邪,随证加减"。扶正固本重在补脾肾,养气血;适时投用祛邪之品需根据机体状况、正邪力量对比来确定;临床诊疗中应根据证候不同进行辨证论治,同时根据其转移部位加减用药,平衡调治。

关键词：乳腺癌复发转移正气亏虚余毒未清痰瘀内阻毒瘀互结林毅

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管道安全保护系统在兰郑长成品油管道的应用

油气田地面工程 2017年第1期36卷 5-7页

作者：刘超王大鹏李怡心徐佳楠郝元放咸玉龙中国石油北京油气调控中心中国石油天然气股份有限公司管道郑州输油气分公司

在管道发生事故工况时,管道安全保护系统是管道输送整体安全受控的主要保障,在保护过程中该系统能够自动触发并执行,不需人工干预,可大大降低管道事故引发的次生灾害。常用的管道安全保护措施包括水击超前保护、进出站泄压保护、自动压... 详细信息

在管道发生事故工况时,管道安全保护系统是管道输送整体安全受控的主要保障,在保护过程中该系统能够自动触发并执行,不需人工干预,可大大降低管道事故引发的次生灾害。常用的管道安全保护措施包括水击超前保护、进出站泄压保护、自动压力越站保护、压力超限保护、紧急停车保护等。针对兰郑长成品油管道,通过离线仿真软件计算得出设计输量下全线水力坡降。在中间泵站用泵情况下,10 s内采取水击超前保护程序,管道全线不会超压,三门峡分输泵站压力越站,实现管道降量输送,管道输量为1 223 m^3/h。在末站罐前阀门误关断时,郑州站关闭信号发出后,10 s内采取水击超前保护程序,管道全线需停输才不会超压。目前管道安全保护设计依托SCADA系统,已经越来越智能化,并形成了一套成熟、完整的系统工程。

关键词：管道安全保护系统自动化智能化泄压水力坡降

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应用于前沿技术节点的集成生产覆盖逐场控制

中国集成电路 2016年第7期25卷 69-75页

作者： Woong Jae Chung John Tristan Karsten Gutjahr Lokesh Subramany Chen Li Yulei Sun Mark Yelverton Young ki kim Jeong Soo kim Chin-Chou Kevin Huang William Pierson Ramkumar Karur-Shanmugam Brent Riggs Sven Jug John C.Robinson Lipkong Yap Vidya Ramanathan GLOBALFOUNDRIES 400 Stone Break Road Extension Malta NY 12020 USA KLA-Tencor corp. 1 Technology Drive Milpitas CA 95035 USA

随着前沿HVM流程节点中不断应用光刻和193nm浸没式多重图形技术,逻辑设备的关键层生产覆盖要求几乎已经达到了扫描仪硬件性能的极限。为了满足HVM生产环境极端覆盖的要求,本次研究调查了前沿技术节点的一个新集成覆盖控制构想,它将运行... 详细信息

随着前沿HVM流程节点中不断应用光刻和193nm浸没式多重图形技术,逻辑设备的关键层生产覆盖要求几乎已经达到了扫描仪硬件性能的极限。为了满足HVM生产环境极端覆盖的要求,本次研究调查了前沿技术节点的一个新集成覆盖控制构想,它将运行到运行(R2R)线性或高阶控制回路、周期逐场或每曝光校正(CPE)晶圆流程标记控制回路,以及扫描仪基线控制回路结合,应用到晶圆厂主机APC系统的一个单一集成覆盖控制路径。目标是满足晶圆厂的覆盖性能要求、降低总拥有成本,并提供自由的控制方法。本文将讨论此构想的一个详细实施案例,以及一些初步的结果。

关键词：覆盖 CPE 残余扫描仪覆盖控制逐场校正每曝光校正基线控制

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毒性中药生川乌质量标准研究

中成药 2006年第5期28卷 651-655页

作者：王兆基关锡耀徐树棋丁大伦粟晓黎林瑞超郑秀云冯国培香港特别行政区政府化验所中国药品生物制品检定所北京100051 香港中文大学

目的:建立毒性中药生川乌的液质联用等质量检验方法。方法:采用显微、化学、液相色谱、液质联用方法进行定性鉴别、含量测定。结果:采用液相色谱质谱/质谱联用具有灵敏、专属性强等优点,适用于微量乌头生物碱的检测。结论:建立的方法可... 详细信息

目的:建立毒性中药生川乌的液质联用等质量检验方法。方法:采用显微、化学、液相色谱、液质联用方法进行定性鉴别、含量测定。结果:采用液相色谱质谱/质谱联用具有灵敏、专属性强等优点,适用于微量乌头生物碱的检测。结论:建立的方法可为其质量标准的提高提供参考。

关键词：生川乌液质联用毒性