检索结果-南通市图书馆

Therapeutic alternatives for the treatment of type 1 hepatorenal syndrome: A Delphi technique-based consensus

World Journal of Hepatology 2016年第25期8卷 1075-1086页

作者： Juan p Arab Juan C Claro Juan p Arancibia Jorge Contreras Fernando Gomez Cristian Munoz Leyla Nazal Eric Roessler Rodrigo Wolff Marco Arrese Carlos Benítez Departamento de Gastroenterología Escuela de Medicina Pontificia Universidad Católica de Chile Departamento de Medicina Interna and programa de salud Basada en la Evidencia Escuela de Medicina Pontificia Universidad Católica de Chile Sección de Gastroenterología Departamento de Medicina Hospital Clínico Universidad de Chile and Clínica Santa María Unidad de Gastroenterología Universidad del Desarrollo Clínica Alemana Servicio de Gastroentero-logía Unidad de Trasplante Hepático Hospital del Salvador Facultad de Medicina Universidad de Chile and Unidad de Gastroenterología Clínica Alemana de Santiago Clínica Indisa Clínica Las Condes y Servicio de Gastroenterología Hospital Fuerza Aérea de Chile Departamento de Nefrología Facultad de Medicina Pontificia Universidad Católica de Chile

AIM To propose several alternatives treatment of type 1 hepatorenal syndrome(HRS-1) what is the most severe expression of circulatory dysfunction on patients with portal *** A group of eleven gastroenterologists and nephrologists performed a structured analysis of available *** expert was designated to review and answer a *** generated draft statements for evaluation by all the *** input was obtained from medical *** order to reach consensus,a modified three-round Delphi technique method was *** to United States preventive Services Task Force criteria,the quality of the evidence and level of recommendation supporting each statement was *** Nine questions were *** available evidence was evaluated considering its quality,number of patients included in the studies and the consistency of its *** generated questions were answered by the expert panel with a high level of ***,a therapeutic algorithm was *** role of terlipressin and norepinephrine was confirmed as the pharmacologic treatment of *** the other hand the use of the combination of octreotide,midodrine and albumin without vasoconstrictors was *** role of several other options was also evaluated and the available evidence was explored and *** transplantation is considered the definitive treatment for *** present consensus is an important effort that intends to organize the available strategies based on the available evidence in the literature,the quality of the evidence and the benefits,adverse effects and availability of the therapeutic tools *** Based on the available evidence the expert panel was able to discriminate the most appropriate therapeutic alternatives for the treatment of HRS-1.

关键词： Hepatorenal syndrome Delphi Consensus Evidence-based medicine Treatment

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Epidemiology of work-related hand and wrist injuries in a referral center: A descriptive study

引用

World Journal of Orthopedics 2024年第7期15卷 650-659页

作者： Angélica M Rodríguez Ginna p Tocanchón Jessica T Villalba Luis M pombo Aníbal A Teherán Gabriel Camero-Ramos Karen p Ayala Gerhard M Acero Research Center Fundación Universitaria Juan N.CorpasBogotá111321Colombia Red Cross Cruz Roja Colombiana-Seccional Cundinamarca BogotáBogotá111221Colombia Vigilancia Epidemiológica Instituto Nacional de SaludBogotá111321Colombia

BACKGROUND Occupational hand and wrist injuries(OHWIs)account for 25%of work-related accidents in low-and middle-income *** Colombia,more than 500000 occupational accidents occurred in 2021,and although the rate declined to less than 5%in 2020 and 2021,at least one in four accidents involved a hand or wrist *** To describe the OHWIs in workers seen at the emergency room at a second-level hospital in *** An observational study was performed using data from workers who experienced OHWIs and attended a second-level hospital,between June,2020 and May,*** overall frequency of OHWIs,as well as their distribution by sociodemo-graphic,clinical,and occupational variables,are ***,association patterns between sex,anatomical area(fingers,hand,wrist),and type of job were analyzed by correspondence analysis(CA).RESULTS There were 2.101 workers treated for occupational accidents,423(20.3%)were cases of OHWIs,which mainly affected men(93.9%)with a median age of 31 years and who worked mainly in mining(75.9%).OHWIs were more common in the right upper extremity(55.3%)and comprised different types of injuries,such as contusion(42.1%),laceration(27.9%),fracture(18.7%),and crush injury(15.6%).They primarily affected the phalanges(95.2%),especially those of the first finger(25.7%).The CAs showed associations between the injured anatomical area and the worker’s job that differed in men and women(explained variance>90%).CONCLUSION One out of five workers who suffered occupational accidents in Cundinamarca,Columbia had an OHWI,affecting mainly males employed in *** occupational profile is likely to lead to prolonged rehabilitation,and permanent functional *** results might be useful for adjusting preventive measures in cluster risk groups.

关键词： Accidents Occupational Epidemiology Hand injuries Wrist injuries Occupational health

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

DLST mutations in pheochromocytoma and paraganglioma cause proteome hyposuccinylation andmetabolic remodeling

引用

Cancer Communications 2023年第7期43卷 838-843页

作者： Sara Mellid Fernando García Luis Javier Leandro-García Alberto Díaz-Talavera Ángel Mario Martínez-Montes Eduardo Gil Bruna Calsina María Monteagudo Rocío Letón Juan María Roldán-Romero María Santos Javier Lanillos Carlos Valdivia Natalia Martínez-puente Javier de Nicolás-Hernández Scherezade Jiménez Manuel pérez-Martínez Emiliano Honrado Javier Coloma Ana Cerezo Clara María Santiveri Manel Esteller Ramón Campos-Olivas Eduardo Caleiras Cristina Montero-Conde Cristina Rodríguez-Antona Javier Muñoz Mercedes Robledo Alberto Cascón Hereditary Endocrine Cancer Group Spanish National Cancer Research Centre(CNIO)MadridSpain proteomics Unit Spanish National Cancer Research Centre(CNIO)MadridSpain Centro de Investigación Biomédica en Red de Enfermedades Raras(CIBERER) MadridSpain Monoclonal Antibodies Core Unit Spanish National Cancer Research Centre(CNIO)MadridSpain Confocal Microscopy Core Unit Spanish National Cancer Research Centre(CNIO)MadridSpain Anatomical pathology Service Hospital of LeónLeónCastilla y LeónSpain Structural Biology programme Spanish National Cancer Research Centre(CNIO)MadridSpain CNIO-Lilly Cell Signalling and Immunometabolism Section Spanish National Cancer Research Centre(CNIO)MadridSpain Spectroscopy and Nuclear Magnetic Resonance Unit Spanish National Cancer Research Centre(CNIO)MadridSpain Josep Carreras Leukaemia Research Institute(IJC) BadalonaBarcelonaSpain Centro de Investigacion Biomedica en Red Cancer(CIBERONC) MadridSpain Institucio Catalana de Recerca i Estudis Avançats(ICREA) BarcelonaSpain physiological Sciences Department School of Medicine and Health SciencesUniversity of Barcelona(UB)L’HospitaletBarcelonaSpain Histopathology Core Unit Spanish National Cancer Research Centre(CNIO)MadridSpain Cell Signaling and Clinical proteomics Group Biocruces Bizkaia Health Research InstituteBarakaldoSpain Ikerbasque Basque Foundation for ScienceBilbaoSpain

Dear Editor,Of all human tumors,pheochromocytomas and paragangliomas(ppGLs)have the highest heritability *** 15%of ppGLs harbor mutations in genes encoding tricarboxylic acid(TCA)cycle-related enzymes that cause oncometabolite accumulation and drive tumorigenesis via metabolic adaptation to hypoxia and global hypermethylation[1].The dihydrolipoamide S-succinyltransferase(DLST)gene was recently described as a new ppGL susceptibility gene[2].

关键词： glioma remodeling cytoma

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Endovascular Emergency Management of Hepatic pseudoaneurism with Vascular plug 4 System with Sacrifice of the Aneurism Nutrient Artery (Report of 2 Cases)

引用

Case Reports in Clinical Medicine 2022年第8期11卷 321-329页

作者： Alejandro Jiménez-Sastré Reynaldo Ramírez-Chacón Miguel Ángel Miranda-Del Olmo Humberto Azuara-Forcelledo Fernando Enrique Mayans-Canabal Jesús Maximiliano Granados-Villalpando Crystell Guadalupe Guzmán-priego Center of Medical Specialties Instituto de Seguridad Social del Estado de Tabasco (ISSET) Villahermosa Mexico Cardiometabolism Laboratory Research Center División Académica de Ciencias de la Salud (DACS) Universidad Juárez Autónoma de Tabasco (UJAT) Villahermosa Mexico

pseudoaneurisms are arterial wounds that affect all layers of an artery;although very rare they are mostly lethal and most of them are iatrogenic. Herein, we present two different cases of hepatic artery pseudoaneurysms derived from previous surgeries which were assessed by computed tomography angiographies and consequent conservative endovascular approaches with arteriographies, posterior cannulations and the placement of Amplatzer Vascular plug 4 (AVp 4) systems in order to treat the pseudoaneurysm. Computed control tomographies were conducted showing no later complications. The purpose of this article is to demonstrate the importance and current clinical applications of AVp in the field of interventional radiology.

关键词： Endovascular Hepatic pseudoaneurysm Interventional Radiology Vascular plug

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

pool of Biological Resources for potential Applications in Solid State Fermentation Obtained from a Forest plantation of pinus pseudostrobus Lindl, Mexico

引用

Advances in Microbiology 2016年第14期6卷 1021-1039页

作者： E. Rodríguez-Bustamante E. Rodríguez-Flores F. Rojas-García A. S. Callejas-Iberri L. M. Gallardo-Roldán S. Gómez-Manzo J. Marcial-Quino M. L. Macías-Rubalcava F. Lazcano-pérez R. Arreguín-Espinosa Departamento de Química de Biomacromoléculas Instituto de Química Universidad Nacional Autónoma de México Mexico City México Departamento de Inmunología Instituto de Investigaciones Biomédicas Universidad Nacional Autónoma de México Mexico City México programa Mexicano del Carbono Texcoco México Laboratorio de Bioquímica Genética Instituto Nacional de Pediatría Secretaría de Salud Mexico City México CONACyT-Instituto Nacional de pediatría Secretaría de Salud Mexico City México Departamento de productos Naturales Instituto de Química Universidad Nacional Autónoma de México Mexico City México

A forest plantation, product of the reforestation of pine trees, represented a pool of biological resources for the implementation of a solid state fermentation process. The trees were identified as pinus pseudostrobus Lindl from which lignocellulosic material in the form of pine needles was collected. Soil fungi, responsible for plant litter decomposition, were cultured at laboratory conditions and tested for their ability to grow on cellulose and hemicellulose as the sole carbon sources. A fungal strain, belonging to the genus penicillium, was selected for growing it on pine needles as the substrate in a solid state culture. After following the culture for six days, the newly isolated strain exhibited a much higher capacity for spore production and holocellulose degradation, compared to a purchased strain of penicillium chrysogenum and two control conditions. This work marks the beginning of future studies focused on commercial applications and represents the first report of a biotechnological process based on pine needles and their degradation by an ascomycetes species belonging to the genus penicillium.

关键词： Forest plantation Solid State Fermentation Lignocellulosic Material pine Needles plant Litter Decomposition Soil Fungi

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

potential of video games for the promotion of neuroadaptation to multifocal intraocular lenses: a narrative review

引用

International Journal of Ophthalmology(English edition) 2019年第11期12卷 1782-1787页

作者： Maria Begona Coco-Martin pedro LValenzuela Miguel JMaldonado-López Alejandro Santos-Lozano Ainhoa Molina-Martin David p pinero Research Unit Hospital Clínico Universitario de Valladolid.ICSCYLValladolid 47003Spain Grupo de Cirugía Refractivay Rehabilitación Visual.Instituto Universitario de Oftalmobiología Aplicada(IOBA) Universidad de ValladolidValladolid 47011Spain physiology Unit Systems Biology DepartmentUniversity of AlcaláMadrid 28801Spain Grupo de Investigación i+Health Departamento de Ciencias de la SaludUniversidad Europea Miguel de CervantesValladolid 47012Spain Department of Optics Pharmacology and AnatomyUniversity of AlicanteAlicante 03690Spain Department of Ophthalmology(IMQO-Oftalmar) Vithas Medimar International HospitalAlicante 03016Spain

Multifocal intraocular lenses(IOLs) are currently usually implanted for the treatment of cataracts because they have been proved to be superior to monofocal IOLs with respect to spectacle independence. In turn, they are associated with a higher prevalence of dysphotopsia symptoms that is one of the most common causes of patient dissatisfaction. Neuroadaptation seems to play a major role in the optimal adaptation to multifocal IOLs. In this context, the development of strategies that facilitate the neuroadaptation process to multifocality might be an effective strategy to reduce patients' dissatisfaction. Video games have been proved to be effective for the improvement of visual acuity and for the promotion of neuroplasticity in elderly subjects and other populations with cortical-related visual impairment. This narrative review highlights the physiological potential of video games as a perceptual strategy to improve visual acuity and promote neuroplasticity in patients using multifocalIOLs, although research is still needed to confirm these benefits in this specific population, with only one comparative study to this date providing evidence of them.

关键词： multifocal intraocular lens dysphotopsia photic phenomena halos video games neuroadaptation neuroplasticity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Fructans from Agave enhance probiotic yoghurt by modulating gut microbiota on children with overweight or obesity

引用

Food Bioscience 2022年第2期46卷 164-172页

作者： Marco U.Martinez-Martinez Daniel V´azquez-Maldonado Stefan Ratering Cesar Godínez-Hern´andez Rosa Isela Ortiz-Basurto Ruth ESoria-Guerra Bellinda Schneider Bertha I.Ju´arez-Flores Diana p.portales-p´erez Sylvia Schnell Fidel Martinez-gutierrez posgrado en Ciencias Farmacobiologicas Universidad Autonoma de San Luis PotosiMexico Institute of Applied Microbiology Justus Liebig University Giessen Germany(3)Instituto de Zonas Deserticas Universidad Autonoma de San Luis PotosiMexico Instituto de Investigaci´on de Zonas Des´erticas Universidad Aut´onoma de San Luis PotosíMexico Laboratorio Integral de Investigaci´on en Alimentos Tecnol´ogico Nacional de Mexico/Instituto Tecnol´ogico de TepicNayaritMexico Centro de Investigaci´on en Ciencias de la salud y Biomedicina Universidad Aut´onoma de San Luis PotosíMexico

Overweight and obesity in children are an increasing public health problem,and the influence the gut microbiota has on it,is still *** consumption of prebiotics has been studied in children with overweight and obesity after an intervention with fermented milk,supplemented with different fructans like prebiotics,was carried out to obtain a healthy *** were randomly assigned into three groups,a double-blind intervention was carried out,receiving different fermented milk products for 6 weeks,including the following supplements:Lactobacillus casei strain Shirota,*** strain Shirota with inulin or *** strain Shirota with fructans from Agave salmiana Otto ex *** was extracted from stool samples and the differential abundance of ASV was monitored by high throughput 16S rRNA gene sequencing.A synbiotic with fructans from *** stimulated the abundance and diversity of the microbiota,specifically on genera Faecalibacterium and Holdemanella,thus,leading to a healthier gut microbiota,which led to obtaining the best anthropometric changes in synbiotic *** intervention may provide health benefits to children with overweight or obesity by increasing the richness of the gut microbiota and stimulate beneficial ***,more studies are needed to get a better understanding of the mechanisms of action.

关键词： Beta diversity Gut microbiota Mexico prebiotic probiotic

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Endothelial progenitor cells as a therapeutic option in intracerebral hemorrhage

引用

Neural Regeneration Research 2017年第4期12卷 558-561页

作者： Juan pías-peleteiro Francisco Campos José Castillo Tomás Sobrino Clinical Neurosciences Research Laboratory Department of NeurologyStroke UnitUniversity Clinical HospitalUniversidade de Santiago de CompostelaHealth Research Institute of Santiago de Compostela (IDIS)

Intracerebral hemorrhage （ICH） is the most severe cerebrovascular disease, which represents a leading cause of death and disability in developed countries. However, therapeutic options are limited, so is mandatory to investigate repairing processes after stroke in order to develop new therapeutic strategies able to promote brain repair processes. Therapeutic angiogenesis and vasculogenesis hold promise to improve outcome of ICH patients. In this regard, circulating endothelial progenitor cells （EpCs） have recently been suggested to be a marker of vascular risk and endothelial function. Moreover, EpC levels have been associated with good neurological and functional outcome as well as reduced residual hematoma volume in ICH patients. Finally, experimental and clinical studies indicate that EpC might mediate endothelial cell regeneration and neovascularization. Therefore, EpC-based therapy could be an excellent therapeutic option in ICH. In this mini-review, we discuss the present status of knowledge about the possible therapeutic role of EpCs in ICH, molecular mechanisms, and the future perspectives and strategies for their use in clinical practice.

关键词： cellular therapy endothelial progenitor cells growth factors intracerebral hemorrhage neurorepair outcome

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

城市中心区的结核病分子流行病学与传统流行病学

引用

国际结核病与肺部疾病杂志 2001年第4期 172-179页

作者： J.Solsona J.A.Caylà E.Verdú M.p.Estrada S.Garcia D.RocaDirección de Asistencia primària (DAp) de Ciutat Vella (Barcelona) reas Básicas de salud (ABS) 'Raval Nord' 'Raval Sud' 'Casc Antic' 'Gàtic' 'Lluís Sayé' y 'Barceloneta' B.Miquel p.Coll F.March the Cooperative Group for Contact Study of Tuberculosis patients in Ciutat Vella 张宗德 Centro de prevención y Control de la Tuberculosis 'Dr Lluís Sayé Servicio de Epidemiologia. Instituto Municipal de la salud Hospital de San pau Servei de Microbiologia Dirección de Asistencia primària (DAp) de Ciutat Vella (Barcelona) reas Básicas de Salud (ABS) 'Raval Nord' 'Raval Sud' 'Casc Antic' 'Gàtic' 'Lluís Sayé' y 'Barceloneta' Departament de Genética i Microbiologia Universidad Autònoma de Barcelona Barcelona Spain

背景:分子流行病学在近期的结核病传播中的重要性得到了加强,但同时也发现了一些与传统流行病学的显著区别。目的:1.在城市中心区的结核病高流行区(163/100000)和有成簇危险的人群中用RFLp法确定成簇病例的百分比。2.比较传统接触者追... 详细信息

背景:分子流行病学在近期的结核病传播中的重要性得到了加强,但同时也发现了一些与传统流行病学的显著区别。目的:1.在城市中心区的结核病高流行区(163/100000)和有成簇危险的人群中用RFLp法确定成簇病例的百分比。2.比较传统接触者追踪法(CCT)与RFLp法的作用。分析:1997-1998年间巴塞罗纳市Ciutat Vella区收集的培养阳性的165例标本,利用IS6110和pTBN12(pGRS)序列进行RFLp分析:对251例公布的病例中的171例(68.1％)进行了接触者追踪调查。通过计算比值比(OR)、使用95％的可信区间(CI)评价它们之间的联系。多变量的分析采用逻辑回归。结果:通过RFLp分析,发现76例(46.0％)的分离株在IS6110和pGRS序列上有成簇现象,通过传统接触者追踪法(CCT),在858名接触者中,发现了30名新病人,57名病人存在关联。就RFLp和CCT调查结果来看,主要危险因素为静脉吸毒(IVDU)。44名独居者病例未包括在传统接触者追踪中,50％的病例用RFLp分析存在成簇。RFLp和CCT法的符合率为8/13(61.5％);5例不符合者为新近的非洲移民。在随后的RFLp分析中15/55例病例发现有流行病学关联。结论:成簇病例的百分率很高。CCT在发现新病例时很有用,但在追踪传播路径时存在缺陷。CCT的覆盖面需要在被忽视的个体及与RFLp结果的符合率方面提高。

关键词：结核(TB) 传统接触追踪(CCT) RFLp 流行病学

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Crohnology: A tale of time and times and inflammatory bowel diseases

引用

World Journal of Gastroenterology 2008年第36期14卷 5489-5490页

作者： Fernando Gomollón Javier p Gisbert Miquel ngel Gassull Hospital Clínico Universitario Zaragoza Spain Centro de Investigación Biomédica en Enfermedades Hepáticas y Digestivas CIBEREHD IACS Spain Hospital Universitario de la princesa CIBEREHD Madrid Spain Instituto de Investigación en Ciéncias de la salud Fundación Germans Trias i Pujol CIBEREHD Badalona Spain

Time, times and timing are key words in inflammatory bowel diseases （IBD）. The leifmotif of this issue or World Journal of Gastroenterology is time. We have asked experts to review on the epidemiology of these diseases over time, the changes in innate immunity that could be present in the first time, and then the timing of key treatments. The correct time of using azathioprine, mercaptopurine, infliximab, cyclosporine and surgery are reviewed. We have chosen experts with not only great clinical expertise but also personal interest in clinical and basic investigation. Our goal in this monograph is to get an idea not only of the present but of the immediate future in some of the key management issues in IBD. To this end, we think that the authors are the most adequate.

关键词： Inflammatory bowel diseases Epidemiology Innate immunity Treatment

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：