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Science Letters:Lattice type transmission line of negative refractive index

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2008年第2期9卷 289-292页

作者： Xin HU sailing he Center for Optical ＆ Electromagnetic Research Zhejiang University Hangzhou 310058 China Division of Electromagnetic Engineering School of Electrical Engineering Royal Institute of Technology S-10044 Stockholm Sweden

In this letter,we introduce a novel passive transmission line of negative refractive index(i.e.,left-handedness)based on identical symmetrical lattice type structures thus called "lattice type transmission line"(LT-TL).The dispersion characteristic and the transmission response of the proposed LT-TL are analyzed.While all the other left-handed passive transmission lines are of high pass,the present passive left-handed transmission line is of low pass.Compared with a conventional transmission line,the LT-TL has a phase shift of 180° in the entire wide pass-band.

关键词：阴极折射电磁学传输线

Ultra-stable near-infrared Tm^(3+)-doped upconversion nanoparticles for in vivo wide-field two-photon angiography with a low excitation intensity

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Journal of Innovative Optical health Sciences 2019年第3期12卷 67-77页

作者： Wen Liu Runze Chen sailing he State Key Laboratory of Modern Optical Instrumentations Centre for Optical and Electromagnetic Research Zhejiang University Hangzhou 310058P.R.China School of Electrical Engineering Royal Institute of Technology Stockholm SE-10044 Sweden

Two-photon luminescence with near-infrared(NIR)excitation of upconversion nanoparticles(NPs)is of great importance in biological imaging due to deep penetration in high-scattering tissues,low auto-luminescence and good sectioning ability.Unfortunately,common two-photon luminescence is in visible band with an extremely high exciation power density,which limits its application.here,we synthesized NaYF_(4):Yb/Tm@NaYF_(4)upconversion NPs with strong twophoton NIR emission and a low excitation power density.Furthermore,NaYF_(4):Yb/Tm@NaYF_(4)@SiO_(2)@OTMS@F127 NPs with high chemical stability were obtained by a modified multilayer coating method which was applied to upconversion NPs for thefirst time.In addition,it is shown that the as-prepared hydrophillic upconversion NPs have great biocompatibility and kept stable for 6 hours during in vivo whole-body imaging.The vessels with two-photon luminescence were clear even under an excitation power density as low as 25mW/cm^(2).Vivid visualizations of capillaries and vessels in a mouse brain were also obtained with low background and high contrast.Because of cheaper instruments and safer power density,the NIR two-photon luminescence of NaYF_(4):Yb/Tm@NaYF_(4)upconversion NPs could promote wider application of two-photon technology.The modified multilayer coating method could be widely used for upconversion NPs to increase the stable time of the in vivo circulation.Our work possesses a great potential for deep imaging and imaging-guided treatment in the future.

关键词： Ultra-stable upconversion nanoparticles two-photon luminescence in vivo brain angiography low excitation power density

Multilayered polyelectrolyte-coated gold nanorods as multifunctional optical contrast agents for cancer cell imaging

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2010年第6期11卷 417-422页

作者： Li-li CheN Li JIANG Ya-lun WANG Jun QIAN sailing he Centre for Optical and Electromagnetic Research State Key Laboratory of Modern Optical Instrumentation Zhejiang University Hangzhou 310058 China Department of Electromagnetic Engineering School of Electrical Engineering Royal Institute of Technology S-100 44 Stockholm Sweden

We report the application of multilayered polyelectrolyte-coated gold nanorods(GNRs) as multifunctional optical contrast agents for cancer cell imaging.The surface modification of GNRs improves their chemical stability and facilitates them to be taken up by cancer cells through electrostatic interaction.The unique longitudinal surface plasmon resonance property of GNRs makes them suitable as both "scattering contrast agents" and "Raman contrast agents".In our experiments,the staining of GNRs in cells was further confirmed by dark field microscopy and Raman microscopy.Our experiment results indicated that GNRs have great potential as multifunctional "optical contrast agents" for future in vivo animal imaging.

关键词：关键词金牌 nanorods 聚合电解质散布拉曼癌症房间成像

Turning a hot spot into a cold spot:polarization-controlled Fano-shaped local-field responses probed by a quantum dot

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Light(Science & Applications) 2020年第1期9卷 417-428页

作者： Juan Xia Jianwei Tang Fanglin Bao Yongcheng Sun Maodong Fang Guanjun Cao Julian Evans sailing he Centre for Optical and Electromagnetic Research State Key Laboratory of Modern Optical InstrumentationNational Engineering Research Center for Optical InstrumentationJORCEPCollege of Optical Science and EngineeringZhejiang University310058 HangzhouChina School of Physics Huazhong University of Science and Technology430074 WuhanChina Centre for Optical and Electromagnetic Research ZJU-SCNU Joint Center of PhotonicsSouth China Academy of Advanced OptoelectronicsSouth China Normal University510006 GuangzhouChina Department of Electromagnetic Engineering School of Electrical EngineeringRoyal Institute of TechnologyS-10044 StockholmSweden

Optical nanoantennas can convert propagating light to local fields.The local-field responses can be engineered to exhibit nontrivial features in spatial,spectral and temporal domains,where local-field interferences play a key role.here,we design nearly fully controllable local-field interferences in the nanogap of a nanoantenna,and experimentally demonstrate that in the nanogap,the spectral dispersion of the local-field response can exhibit tuneable Fano lineshapes with nearly vanishing Fano dips.A single quantum dot is precisely positioned in the nanogap to probe the spectral dispersions of the local-field responses.By controlling the excitation polarization,the asymmetry parameter q of the probed Fano lineshapes can be tuned from negative to positive values,and correspondingly,the Fano dips can be tuned across a broad spectral range.Notably,at the Fano dips,the local-field intensity is strongly suppressed by up to ~50-fold,implying that the hot spot in the nanogap can be turned into a cold spot.The results may inspire diverse designs of local-field responses with novel spatial distributions,spectral dispersions and temporal dynamics,and expand the available toolbox for nanoscopy,spectroscopy,nano-optical quantum control and nanolithography.

关键词： quantum local dispersion

Energy intensity analysis of modes in hybrid plasmonic waveguide

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光电子前沿（英文版） 2012年第1期5卷 68-72页

作者： Ruixi ZENG Yuan ZHANG sailing he Centre for Optical and Electromagnetic Research State Key Laboratory of Modem Optical InstrumentationsZhejiang UniversityHangzhou 310058China Joint Research Center of Photonics of Zhejiang University and South China Normal University South China Normal UniversityGuangzhou 510006China

包含硅核心，银帽子和极端薄的夹的 SiO2 层的混合 plasmonic 波导被学习。由分析模式分发模式和模式的曲线有效索引，我们显示出在金属表面附近的 plasmonic 模式怎么被结合在到表格的硅核心的基本模式一个挤压的混合模式。在精力监禁... 详细信息

包含硅核心，银帽子和极端薄的夹的 SiO2 层的混合 plasmonic 波导被学习。由分析模式分发模式和模式的曲线有效索引，我们显示出在金属表面附近的 plasmonic 模式怎么被结合在到表格的硅核心的基本模式一个挤压的混合模式。在精力监禁的混合 plasmonic 波导的能力是也讨论的份量上。

关键词：混合模式波导模式电浆强度分析能源 SiO2层有效折射率分布格局

Stretching the spectra of Kerr frequency combs with self-adaptive boundary silicon waveguides

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Advanced Photonics 2020年第4期2卷 29-38页

作者： Jianhao Zhang Vincent Pelgrin Carlos Alonso-Ramos Laurent Vivien sailing he Eric Cassan UniversitéParis-Saclay CNRSCentre de Nanosciences et de NanotechnologiesPalaiseauFrance Zhejiang University Centre for Optical and Electromagnetic ResearchState Key Laboratory for Modern Optical InstrumentationHangzhouChina

Dispersion engineering of optical waveguides is among the most important steps in enabling the realization of Kerr optical frequency combs.A recurring problem is the limited bandwidth in which the nonlinear phase matching condition is satisfied,due to the dispersion of the waveguide.This limitation is particularly stringent in high-index-contrast technologies such as silicon-on-insulator.We propose a general approach to stretch the bandwidth of Kerr frequency combs based on subwavelength engineering of single-mode waveguides with self-adaptive boundaries.The wideband flattened dispersion operation comes from the particular property of the waveguide optical mode that automatically self-adapts its spatial profile at different wavelengths to slightly different effective spatial spans determined by its effective index values.This flattened dispersion relies on the squeezing of small normal-dispersion regions between two anomalous spectral zones,which enables it to achieve two Cherenkov radiation points and substantially broaden the comb,achieving a bandwidth between 2.2 and 3.4μm wavelength.This strategy opens up a design space for trimming the spectra of Kerr frequency combs using high-index-contrast platforms and can provide benefits to various nonlinear applications in which the manipulation of energy spacing and phase matching are pivotal.

关键词： nonlinear optics effective boundary subwavelength grating silicon frequency comb

Targeted and imaging-guided in vivo photodynamic therapy for tumors using dual-function, aggregation- induced emission nanoparticles

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Nano Research 2018年第5期11卷 2756-2770页

作者： Xianhe Sun Abudureheman Zebibula Xiaobiao Dong Gonghui Li Guanxin Zhang Deqing Zhang Jun Qian sailing he State Key Laboratory of Modern Optical Instrumentations Centre for Optical and Electromagnetic Research Zhejiang University Hangzhou 310058 China Department of Urology Sir Run Run Shaw Hospital College of Medicine Zhejiang University Hangzhou 310016 China Beijing National Laboratory for Molecular Sciences CAS Key Laboratories of Organic Solids and Analytical Chemistry for Living Biosystems Institute of Chemistry Chinese Academy of Sciences Beijing 100190 China School of Electrical Engineering Royal Institute of Technology OSQULDAS VAG 6 Stockholm SE-10044 Sweden

Imaging-guided photodynamic therapy （PDT） has been regarded as a promising strategy for precise cancer treatment. Because of their excellent modifiability and drug-loading capacity, nanoparticles have played an important role in PDT. Nonetheless, when traditional photosensitizers are made into nanoparticles, both their fluorescence and reactive oxygen species generation efficacy decrease due to a phenomenon known as aggregation-caused quenching. Fortunately, in recent years, several kinds of organic dyes with ＂abnormal＂ properties （termed aggregation-induced emission, AIE） were developed. With enhanced fluorescence emission in the nanoaggregation state, the traditional obstacles mentioned above may be overcome by AIE luminogens. herein, we provide a better combination of photosensitizers and nanoparticles, namely, dual-function AIE nanopartides capable of producing reactive oxygen species, to implement targeted and imaging-guided in vivo PDT. Good contrast of in vivo imaging and obvious therapeutic efficacy were observed at a low dose of AIE nanoparticles and low irradiance of light, thus resulting in negligible side effects. Our work shows that AIE nanopartides may play a promising role in imaging-guided clinical PDT for cancer in the near future.

关键词： aggregation-induced emission,targeted therapy,imaging-guided therapy,photodynamic therapy,tumor

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利用结合局域优化的遗传算法求解脑磁逆问题

电子与信息学报 2002年第6期24卷 800-804页

作者：李军朱红毅 sailing he 浙江大学现代光学仪器国家重点实验室光及电磁波研究中心杭州310027 浙江近代物理中心 Dept.of Electromag.Theory Royal Isstitute of TechnologyStockholmSweden

脑磁逆问题的求解是脑磁研究中的一个关键问题,其中对多电流偶极子源参数的推断一般采用非线性全局优化方法,但收敛速度较慢。为提高计算速度,该文采用结合局域优化的遗传算法,既克服了局域优化的局部极小问题,又可以加快收敛速度。基... 详细信息

脑磁逆问题的求解是脑磁研究中的一个关键问题,其中对多电流偶极子源参数的推断一般采用非线性全局优化方法,但收敛速度较慢。为提高计算速度,该文采用结合局域优化的遗传算法,既克服了局域优化的局部极小问题,又可以加快收敛速度。基于真实头模型的仿真计算表明该方法是有效的。

关键词：局域优化遗传算法脑磁逆问题

All-optical two-channel polarization-multiplexing format conversion from QPSK to BPSK signals in a silicon waveguide

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Photonics Research 2016年第6期4卷 245-248页

作者： Xianglian Feng Zhihang Wu Xiaoyan Wang sailing he Shiming Gao Centre for Optical and Electromagnetic Research State Key Laboratory of Modern Optical InstrumentationZhejiang University

All-optical two-channel format conversion is proposed and experimentally demonstrated from a 40 Gbit/s polarization multiplexing(Pol-MUX) non-return-to-zero quadrature phase-shift keying(QPSK) signal to Pol-MUX binary phase-shift keying(BPSK) signals by using phase-doubled four-wave mixing effects with two polarization-angled pumps in a silicon waveguide. The eye diagrams and constellation diagrams of the original QPSK sequences and the converted BPSK sequences of each channel are clearly observed on the two polarization states. Moreover,the bit error rates(BERs) of the two converted idlers are measured. The power penalties of all these converted BPSK sequences on both X and Y polarization states are less than 3.4 dB at a BER of 3.8 × 10^(-3).

关键词： QPSK BPSK All-optical two-channel polarization-multiplexing format conversion from QPSK to BPSK signals in a silicon waveguide MUX FWM