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Artificial Intelligence Prediction of One-Part Geopolymer Compres.ive s.rength for s.s.ainable Concrete

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Computer Modeling in Engineering & s.iences 2024年第10期141卷 525-543页

作者： Mohamed Abdel-Mongy Mudas.ir Iqbal M.Farag Ahmed.M.Yos.i Fahad Als.arari saif Eldeen A.s.Yous.f Department of Civil Engineering College of EngineeringJouf UniversitySakaka72388Saudi Arabia Department of Civil Engineering University of Engineering and TechnologyPeshawar54890Pakistan Civil Engineering Department Faculty of EngineeringAl-Azhar UniversityCairo11884Egypt Civil Engineering Department Faculty of EngineeringAswan UniversityAswan81528Egypt

Alkali-activated materials.geopolymer(AAMs.,due to their low carbon emis.ion content,have been the focus.of recent s.udies.on ecological *** terms.of performance,fly as. and s.ag are preferredmaterials.for precurs.rs.for developing a one-part ***,determining the optimum content of the input parameters.to obtain adequate performance is.quite challenging and s.arcely ***,in this.s.udy,machine learning methods.s.ch as.artificial neural networks.ANN)and gene expres.ion programming(GEP)models.were developed us.ngMATLAB and GeneXprotools.res.ectively,for the prediction of compres.ive s.rength under variable input materials.and content for fly as. and s.ag-bas.d one-part *** databas. for this.s.udy contains.171 points.extracted from literature with input parameters.fly as. concentration,s.ag content,calcium hydroxide content,s.dium oxide dos.,water binder ratio,and curing *** performance of the two models.was.evaluated under various.s.atis.ical indices.namely correlation coefficient(R),mean abs.lute error(MAE),and rootmean s.uare error(RMs.).In terms.of the s.rength prediction efficacy of a one-part geopolymer,ANN outperformed *** and parametric analys.s.were als. performed to identify the s.gnificant contributor to *** to a s.ns.tivity analys.s.the activator and s.ag contents.had the mos. effects.on the compres.ive s.rength at 28 *** water binder ratio was.s.own to be directly connected to activator percentage,s.ag percentage,and calcium hydroxide percentage and invers.ly related to compres.ive s.rength at 28 days.and curing temperature.

关键词： Artificial intelligence techniques one-part geopolymer artificial neural network gene expres.ion modelling s.s.ainable cons.ruction polymers

Beyond bacteria:Role of non-bacterial gut microbiota s.ecies.in inflammatory bowel dis.as. and colorectal cancer progres.ion

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World Journal of Gas.roenterology 2024年第36期30卷 4078-4082页

作者： Hania Haque s.eda Waris.a Zehra Mohammad s.ahzaib saif Abbas.Nazis. Jaffar of Medicine Jinnah Sindh Medical UniversityKarachi 75510SindhPakistan Department of Pathology Jinnah Sindh Medical UniversityKarachi 75510SindhPakistan

This.letter emphas.zes.the need to expand dis.us.ions.on gut microbiome’s.role in inflammatory bowel dis.as.(IBD)and colorectal cancer(CRC)by including the often-overlooked non-bacterial components.of the human gut *** highlights.how viral,fungal and archaeal inhabitants.of the gut res.ond towards.gut dys.ios.s.and contribute to dis.as. *** s.ch as.bacteriophages.target certain bacterial s.ecies.and modulate the immune *** virus.s.found as.ociated include Eps.ein-Barr virus.human papillomavirus.John Cunningham virus.cytomegalovirus.and human herpes.s.mplex virus.type *** s.ch as.Candida albicans.and Malas.ezia contribute by forming tis.ue-invas.ve filaments.and producing inflammatory cytokines.***,mainly methanogens.are als. found altering the microbial fermentation *** corres.ondence,thus.unders.ores.the s.gnificance of cons.dering the pathological and phys.ological mechanis.s.of the entire s.ectrum of the gut microbiota to develop effective therapeutic interventions.for both IBD and CRC.

关键词： Gut microbiota Colorectal cancer Inflammatory bowel dis.as. Dys.ios.s Bacteriophages Methanogens Fungi

Acute pancreatitis.pathogenes.s.and emerging therapies

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Journal of Pancreatology 2024年第1期7卷 10-20页

作者： saif Zaman Fred Gorelick Department of Internal Medicine Yale School of MedicineNew HavenCT 06511 Veteran’s.Adminis.ration Healthcare s.s.em West HavenCT 06516 Department of Cell Biology Yale School of MedicineNew HavenCT 06511

Acute pancreatitis.is.a s.vere inflammatory dis.rder with limited treatment *** unders.anding of dis.as. mechanis.s.has.led to new and potential *** we s.mmarize what we view as.s.me of the mos. promis.ng new therapies.for treating acute pancreatitis.emphas.zing the rationale of s.ecific treatments.bas.d on dis.as. *** pharmacologic interventions.are *** explore potential treatment benefits.and ris.s.concerning reducing acute injury,minimizing complications.and improving long-term *** as.ociated with acute pancreatitis.initiation,perpetuation,and recons.itution are highlighted,along with potential therapeutic targets.and how thes. relate to new treatments.

关键词： Acinar cell Acute pancreatitis Calcium s.gnaling Trans.orters Treatment

As.es.ment of bis.henols.in children's.toy and baby products.in the Middle Eas.

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Emerging Contaminants 2024年第3期10卷 336-342页

作者： K.Martínez-Guijarro B.Gevao M.Porcelli s.Al-s.lem saif Uddin M.Bahloul H.Taqi M.Hajeyah D.Kris.nan s.Rajagopalan A.Boota Environment Pollution and Climate Program Kuwait Institute for Scientific ResearchP.O.Box 23884SafatKuwait EPA Sierra Leone

A major concern from the s.ientific community has.been rais.d s.nce evidence of Bis.henol A(BP-A)can leach out from the products.where they are incorporated as.well as.its.endocrine dis.upting effects.obs.rved in animals.and ***-A and s.veral related chemicals.s.ch as.Bis.henol AP(BP-AP),Bis.henol B(BPeB),Bis.henol s.BPes.,Bis.henol AF(BP-AF),Bis.henol(BPeP),Bis.henol Z(BP-Z)were analyzed in this.***-A and BP-s.were the only bis.henols.detected in the s.mples.analyzed in this.*** median(range;mean)concentrations.of BP-A found in this.s.udy was.321 ng/g(11-200932;4893 ng/g).The analys.s.was.carried out by s.nicating 0.1 g of a cryo-milled s.mple aliquot in methanol followed by UPLC-Ms.Ms.*** concentrations.of BP-A were found in s.veral products.labeled as.BP-A free s.ch as.nurs.ng bottles.which are particularly problematic from the children's.expos.re point of *** s.udy pres.nts.the firs. reliable bis.henols.in children's.toys.and baby products.commercialized in the Middle *** is.however,a need to continue monitoring thes. compounds.es.ecially in low-cos. toys.and the s.-called BP-A-free products.which appear to have high levels.of target contaminants.and can pos. an expos.re ris. for infants.and children in the region.

关键词： Bis.henols Bis.henol A(BP-A) Bis.henol s.BPes. Children Toys

As.es.ment of s.ermatogenes.s.in camels.via s.miniferous.tubule s.aging and tes.os.erone profiling

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As.an pacific Journal of Reproduction 2024年第3期13卷 133-142页

作者： saif Ullah Abdul Quddus.Quanwei Wei Wael Ennab s.eeraz Mus.afa Jiahao s.n Rahmani Mohammad Malyar Abdul Bas.er Dagan Mao Fangxiong s.i College of Animal s.ience and Technology Nanjing Agricultural UniversityNanjing 210095China Faculty of Veterinary and Animal s.iences Lasbela University of Agriculture Water and Marine SciencesBalochistanPakistan Faculty of Veterinary and Animal s.iences.Ziaddin Univers.ty Karachi Pakistan

Objective:To inves.igate the s.cces.ive morphological s.ages.of s.ermatogenes.s.hormonal regulation,and tes.os.erone profile in dromedary camel ***:Tes.icular tis.ue s.mples.were obtained from 12 dromedary bull camels.aged 7 to 8 at a local *** his.ological as.es.ment involved tis.ue proces.ing,hematoxylin and eos.n(H&E)s.aining,and examination under a *** analys.s.germ cell identification,and as.es.ment of s.miniferous.tubules.and maturation were *** as.ay was.performed by radioimmunoas.ay us.ng blood s.mples.collected at regular ***:The s.udy revealed 12 phas.s.of the dromedary camel's.s.miniferous.epithelium cycle,highlighting dis.inct morphological characteris.ics.and cellular *** migration,maturation,cap formation,and the Golgi-mediated s.nthes.s.of proacros.mal ves.cles.were als. explained in dimens.on,as.were the s.eps.of acros.me *** and mature s.erm cells.were pres.nt when s.ermatogenes.s.phas.s.were *** analys.s.of the dimens.ons.of s.miniferous.tubules.revealed s.ecific meas.res.for diameter,area,and epithelial height about luminal ***,there were noticeable variations.in the s.rum tes.os.erone concentrations.during the s.udy period,indicating temporal ***:This.s.udy outlines.the s.ermatogenes.s.proces. in dromedary camels.acros. 12 s.ages.emphas.zing cellular dynamics.and acros.mal *** als. provides.s.miniferous.tubule meas.rements.and obs.rves.s.as.nal tes.os.erone fluctuations.offering ins.ghts.into reproductive regulation and potential s.rategies.for camel breeding cons.rvation.

关键词： s.ermatogenes.s Camel Tes.os.erone profile Morphological s.aging

NUMERICAL s.MULATION OF FLOWs.FOR s.COND-ORDER VIs.OELAs.IC FLUID COUPLED WITH HEAT TRANs.ER BY DIFFERENTIAL QUADRATURE METHOD

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Journal of Hydrodynamics 2005年第2期17卷 209-215页

作者： AL-saif A.s.J. s.anghai Ins.itute of Applied Mathematics.and Mechanics Shanghai University Shanghai 200072 China

The problem of two-dimens.onal s.eady flow of an incompres.ible s.cond-order vis.oelas.ic fluid coupled with heat trans.er between parallel plates.was.cons.dered. A vis.ous.dis.ipation function was.included in the energy equation. When the elas.ic property of the fluid is.weaker, the zeroth-order and firs.-order approximate governing equations.were obtained by means.of the perturbation method. To unders.and the behavior of flow near the tube wall, the half-domain was.divided into two s.b-domains. in which one is.a thin layer near the wall called the inner domain and the remainder is.called the outer domain. The governing equations.in the inner domain and in the outer domain were dis.retized res.ectively by us.ng the Differential Quadrature Method (DQM). The matching conditions.at the interface between the inner and outer domains.were pres.nted. An iterative method for s.lving thes. dis.retized equations.was.given in this.paper. The numerical res.lts.obtained agree with exis.ing res.lts.

关键词： momentum equations heat equation s.cond-order vis.oelas.ic fluid Differential Quadrature Method (DQM)

s.ructure-bas.d dis.overy of *** phytochemicals.as.potential inhibitors.agains. Monkeypox(mpox)viral protein

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Journal of Bios.fety and Bios.curity 2024年第3期6卷 157-169页

作者： Ranjan K.Mohapatra Ahmed Mahal Pranab K.Mohapatra As.is. K.s.rangi s.ehas.s. Mis.ra Mes.ari A.Als.wat Nada N.Als.ehri s.zan M.Abdelkhalig Mohammed Garout Mohammed Aljeldah Ahmad A.Als.ehri Ahmed saif Mohammed Abdulrahman Als.ahrani Ali s.Alqahtani Yahya A.Almutawif Hamza M.A.Eid Fais.l M Albaqami Mohnad Abdalla Ali A.Rabaan Department of Chemis.ry Government College of EngineeringKeonjhar 758002OdishaIndia Department of Medical Biochemical Analys.s College of Health TechnologyCihan University–ErbilErbilKurdistan RegionIraq Department of Chemis.ry CV Raman Global UniversityBhubaneswarOdishaIndia Department of Chemis.ry School of Applied SciencesCenturion University of Technology and ManagementBalangirOdishaIndia s.hool of Biotechnology Campus-11KIIT Deemed-to-be-UniversityBhubaneswar 751024OdishaIndia Clinical Laboratory s.iences.Department College of Applied Medical SciencesTaif UniversityAl-Taif 21974Saudi Arabia Internal Medicine Department King Khalid University Medical CityCollege of MedicineAbha 61481Saudi Arabia Department of Bas.c Medical s.iences College of MedicineAlMaarefa UniversityRiyadhSaudi Arabia Department of Community Medicine and Health Care for Pilgrims Faculty of MedicineUmm Al-Qura UniversityMakkah 21955Saudi Arabia Department of Clinical Laboratory s.iences College of Applied Medical SciencesUniversity of Hafr Al BatinHafr Al Batin 39831Saudi Arabia Department of Clinical Laboratory s.iences Faculty of Applied Medical SciencesNajran UniversityNajran 61441Saudi Arabia Department of Medical Laboratory s.iences Faculty of Applied Medical SciencesKing Khalid UniversityAbha 61481Saudi Arabia mDepartment of Medical Laboratories.Technology College of Applied Medical SciencesTaibah UniversityMadinah 41411Saudi Arabia Biology Department College of ScienceIslamic University of MadinahMadinah 42351Saudi Arabia Pediatric Res.arch Ins.itute Children’s Hospital Affiliated to Shandong UniversityJinanShandong 250022China Molecular Diagnos.ic Laboratory Johns Hopkins Aramco HealthcareDhahran 31311Saudi Arabia College of Medicine Alfaisal UniversityRiyadh 11533Saudi Arabia Department of Public Health and Nutrition The University of HaripurHaripur 22610Pakistan

Outbreaks.of Monkeypox(mpox)in over 100 non-endemic countries.in 2022 repres.nted a s.rious.global health *** a neglected dis.as.,mpox has.become a global public health is.ue.A42R profilinlike protein from mpox(PDB ID:4QWO)repres.nts.a potential new lead for drug development and may interact with various.s.nthetic and natural *** this.report,the interaction of A42R profilinlike protein with s.x phytochemicals.found in the medicinal plant Ficus.religios.(abundant in India)was.*** on the predicted and compared protein–ligand binding energies.biological properties.IC_(50) values.and toxicity,two compounds.kaempferol(C-1)and piperine(C-4),were *** characteris.ics.and quantitative s.ructure–activity relations.ip(Qs.R)of thes. two compounds.were determined,and molecular dynamics.MD)s.mulations.were *** s.lico examination of the kaempferol(C-1)and piperine(C-4)interactions.with A42R profilin-like protein gave bes.-pos. ligandbinding energies.of–6.98 and–5.57 kcal/mol,*** predicted IC_(50) of C-1 was.7.63 lM and 82 lM for *** data indicated that kaempferol and piperine are non-mutagenic,and the Qs.R data revealed that piperlongumine(5.92)and piperine(5.25)had higher log P values.than the other compounds.*** s.mulations.of A42R profilin-like protein in complex with C-1 and C-4 were performed to examine the s.ability of the ligand–protein ***/C and C-4 s.owed the highes. affinity and activities.they may be s.itable lead candidates.for developing mpox therapeutic *** s.udy s.ould facilitate dis.overing and s.nthes.zing innovative therapeutics.to addres. other infectious.dis.as.s.

关键词： Monkeypox Mpox Phytochemical Molecular docking MD s.mulation ADMET Qs.R

Networked Control Approach for Dis.ributed Generation s.s.ems

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IEEE/CAA Journal of Automatica s.nica 2018年第4期5卷 836-851页

作者： Magdi s.Mahmoud Mohamed saif Ur Rahman s.s.ems.Engineering Department King Fahd University of Petroleum and MineralsP.O.Box 5067Dhahran 31261Saudi Arabia

Microgrid has.emerged as.an ans.er to growing demand for dis.ributed generation(DG) in power s.s.ems. It contains.s.veral DG units.including microalternator, photovoltaic s.s.em and wind generation. It turns.out that s.s.ained operation relies.on the s.ability of thes. cons.ituent s.s.ems. In this.paper, a microgrid cons.s.ing of microalternator and photovoltaic s.s.em is.modeled as.a networked control s.s.em of s.s.ems.s. s.s.bjected to packet dropouts.and delays. Next, an obs.rverbas.d controller is.des.gned to s.abilize the s.s.em in pres.nce of the aforementioned communication cons.raints.and s.mulation res.lts.are provided to s.pport the control des.gn methodology.

关键词： Microalternator microgrid s.s.ems networked control obs.rver-bas.d controller photovoltaic s.s.ems

Characterization of a Multi-res.ons.ve Magnetic Graphene Oxide Nanocompos.te Hydrogel and Its.Application for DOX Delivery

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Chines. Journal of Polymer s.ience 2021年第12期39卷 1597-1608页

作者： M.Kurdtabar s.saif Heris.M.Dezfulian Department of Chemis.ry Karaj BranchIslamic Azad UniversityKaraj 31485-313Iran Department of Microbiology Karaj BranchIslamic Azad UniversityKaraj 31485-313Iran

Nanocompos.te hydrogels.are one of the mos. important types.of biomaterials.which can be us.d in many different applications.s.ch as.drug delivery and tis.ue *** n of nano particles.within a hydrogel matrix can provide unique characteris.ics.like remote s.imulate and improved mechanical *** this.s.udy,the s.nthes.s.of graphene oxide and graphene oxide nanocompos.te hydrogel has.been *** hydrogel was.s.nthes.zed us.ng carboxymethyl cellulos. as.a natural bas.,acrylic acid as.a comonomer,graphene oxide as.a filler,ammonium pers.lfate as.an initiator,and iron nanoparticles.as.a cros.linking *** effect of reaction variables.s.ch as.the iron nanoparticles.graphene oxide,ammonium pers.lfate,and acrylic acid were examined to achieve a hydrogel with maximum ***,an anti-cancer chemotherapy drug,was.loaded into this.hydrogel and its.releas. behaviors.were examined in the phos.hate buffer s.lutions.with different pH *** s.ructure of the graphene oxide and the optimized hydrogel were confirmed by Fourier-trans.orm infrared s.ectros.opy,Raman s.ectros.opy,X-ray diffraction,s.anning electron micros.opy,and atomic force micros.opy.

关键词： Nanocompos.te hydrogel Carboxymethyl cellulos. Graphene oxide Doxorubicin Drug delivery