检索结果-南通市图书馆

Ebola viral disease: a review literature

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Biomedicine 2015年第4期5卷 260-267页

作者： saeed Reza Jamali moghadam Negar Omidi Samaneh Bayrami Sepideh Jamali moghadam SeyedAhmad SeyedAlinaghi Ziaeian Hospital Tehran University of Medical Sciences Iranian Research Center for HIV/AIDS (IRCHA) Iranian Institute for Reduction of High-Risk Behaviors Tehran University of Medical Sciences

Ebola virus is transmitted to people as a result of direct contact with body fluids containing virus of an infected patient. The incubation period usually lasts 5 to 7 d and approximately95% of the patients appear signs within 21 d after exposure. Typical features include fever,profound weakness, diarrhea, abdominal pain, cramping, nausea and vomiting for 3-5days and maybe persisting for up to a week. Laboratory complications including elevated aminotransferase levels, marked lymphocytopenia, and thrombocytopenia may have *** fever occurs in less than half of patients and it takes place most commonly in the gastrointestinal tract. The symptoms progress over the time and patients suffer from dehydration, stupor, confusion, hypotension, multi-organ failure, leading to fulminant shock and eventually death. The most general assays used for antibody detection are direct IgG and IgM ELISAs and IgM capture ELISA. An IgM or rising IgG titer(four-fold) contributes to strong presumptive diagnosis. Currently neither a licensed vaccine nor an approved treatment is available for human use. Passive transfer of serum collected from survivors of Junin virus or Lassa virus, equine IgG product from horses hypervaccinated with Ebola virus, a "cocktail"of humanized-mouse antibodies(ZMapp), recombinant inhibitor of factor VIIa/tissue factor,activated protein C, RNA-polymerase inhibitors and small interfering RNA nano particles are among the therapies in development. Preclinical evaluation is also underway for various vaccine candidates. One is a chimpanzee adenovirus vector vaccine; other vaccines involve replication-defective adenovirus serotype 5 and recombinant vesicular stomatitis virus.

关键词： Filoviridae Ebola Outbreak Reservoir Transmission Symptoms Hemorrhagic fever Index case ELISA Vaccine

Employing Orphan Nodes to Avoid Energy Holes in Wireless Sensor Networks

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Communications and Network 2013年第3期5卷 625-630页

作者： Sepideh Zareei Elham Babaee Rosli Salleh saeed moghadam Faculty of Computer Science and Information Technology University of Malaya Kuala Lumpur Malaysia Faculty of Electrical IT and Computer Sciences Qazvin Islamic Azad University Qazvin Iran

When energy consumption by wireless sensor nodes gets off balance, partitions in the network appear because several of the nodes stop functioning. The respective network’s lifetime also diminishes. This problem is commonly known as the “hot spot” or “energy hole” phenomenon. To resolve this issue, a Multi-Hop Decentralized Cluster-Based Routing (MDCR) protocol is proposed. This algorithm uses orphan nodes as intermediate nodes to form inter-cluster multi-hop routing and balance the energy consumption among sensor nodes. Simulation experiments have shown that MDCR is significantly better at prolonging network lifetime compared to the Adaptive Decentralized Re-Clustering Protocol.

关键词： Wireless Sensor Networks Clustering Energy Efficiency Orphan Nodes

Transient receptor potential channels and calcium dysregulation: a pathogenic duo in Parkinson's disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第3期20卷 808-810页

作者： Iqira saeed Linlin Ma Griffith Institute for Drug Discovery Griffith UniversityNathanBrisbaneQLDAustralia School of Environment and Science Griffith University NathanBrisbaneQLDAustralia

Parkinson's disease(PD) has a complex and multifactorial pathophysiology. Various studies, conducted both in pre-clinical models and PD patients, have reported a link between the disruption of calcium(Ca^(2+)) homeostasis and the subsequent development of PD. Ca^(2+) regulation is crucial for neuronal survival, differentiation,exocytosis at synapses,gene transcription,and proliferation.

关键词： homeostasis clinical subsequent

Unveiling the impact:COVID-19's influence on bacterial resistance in the Kingdom of Bahrain

在线全文

学校读者我要写书评

暂无评论

World Journal of Virology 2025年第1期14卷 83-98页

作者： Nermin K saeed Safiya K Almusawi Noor A Albalooshi Mohammed Al-Beltagi Medical Microbiology Section Department of PathologySalmaniya Medical ComplexGovernmental HospitalsManama 12Bahrain Medical Microbiology Section Department of PathologyRoyal College of Surgeons in Ireland-Medical University of BahrainBusaiteen 15503MuharraqBahrain Department of Paediatrics Faculty of MedicineTanta UniversityTanta 31511AlghrabiaEgypt Department of Pediatric University Medical CenterKing Abdulla Medical CityArabian Gulf UniversityManama 26671AlgharbiaBahrain

BACKGROUND Antibiotic resistance is a growing global health threat,and understanding local trends in bacterial isolates and their susceptibility patterns is crucial for effective infection control and antimicrobial *** coronavirus disease 2019(COVID-19)pandemic has introduced additional complexities,potentially influencing these *** To analyze trends in bacterial isolates and their antibiotic susceptibility patterns at Salmaniya Medical Complex from 2018 to 2023,with a specific focus on the impact of the COVID-19 pandemic on these *** A retrospective analysis of microbiological data was conducted,covering the period from 2018 to *** study included key bacterial pathogens such as Escherichia coli(***),Klebsiella pneumoniae,Acinetobacter baumannii,Pseudomonas aeruginosa,and Staphylococcus aureus,among *** antibiotic susceptibility profiles of these isolates were assessed using standard laboratory *** contextualize the findings,the findings were compared with similar studies from other regions,including China,India,Romania,Saudi Arabia,the United Arab Emirates,Malaysia,and United *** The study revealed fluctuating trends in the prevalence of bacterial isolates,with notable changes during the COVID-19 *** example,a significant increase in the prevalence of Staphylococcus aureus was observed during the pandemic years,while the prevalence of *** showed a more variable *** resistance rates varied among the different pathogens,with a concerning rise in resistance to commonly used antibiotics,particularly among Klebsiella pneumoniae and ***,the study identified an alarming increase in the prevalence of multidrug-resistant(MDR)strains,especially within Klebsiella pneumoniae and *** *** impact of the COVID-19 pandemic on these trends was evident,with shifts in the frequency,resistance patterns,and the emergence of MDR bacteria among several key ***

关键词： Multidrug-resistant organisms Antibiotic susceptibility COVID-19 pandemic Antimicrobial stewardship Bacterial isolates Salmaniya Medical Complex Bahrain

An efficient built-up land expansion model using a modified U-Net

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Digital Earth 2022年第1期15卷 148-163页

作者： Hanieh Shojaei saeed Nadi Hossein Shafizadeh-moghadam Amin Tayyebi John Van Genderen Department of Geomatics Engineering University of IsfahanIsfahanIran Department of Civil and Environmental Engineering Carleton UniversityOttawaCanada Department of Water Resources Engineering and Management Tarbiat Modares UniversityTehranIran Data Science Manager Exelon UtilityChicagoILUSA Department of Earth Observation Sciences (ITC) University of TwenteEnschedeThe Netherlands

This paper introduces an improved convolutional neural network based on the conventional U-Net for simulating built-up land *** proposed method hires a pixel-wise semantic segmentation approach considering the spatial drivers affecting urbanization as data *** variables including altitude,slope,and distance from barren,crop,greenery,roads,and urban areas for 1998,2008,and 2018 were considered as covariates for the simulation of built-up land expansion in Tehran and Karaj regions in *** proposed method was compared with the random forest(RF)algorithm as the baseline *** using the area under the total operating characteristic indicated the superiority of our modified U-Net(0.87)over the RF(0.82)***,evaluation using the percent correct metric indicated that our proposed model is capable of learning neighborhood effects effectively leading to simulate built-up land expansion accurately,independent from applying a cellular automata(CA)***,the modified U-Net independent from the CA which can consider the neighborhood effects is recommended for the simulation of built-up land expansion precisely.

关键词： Land use and land cover change built-up land expansion convolutional neural networks pixel-wise semantic segmentation U-Net total operating characteristic(TOC)

Bedload Sediment Rate Prediction for the Sand Transport Along Coastal Waters in Ocean Management Strategy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

China Ocean Engineering 2020年第6期34卷 840-852页

作者： saeed KHORRAM Department of Civil Engineering Marvdasht BranchIslamic Azad UniversityMarvdasht 73711-13119Iran

Interactions among different landforms and varied complicated physical processes cause sediment transport in coastal regions being the interest of ocean management planning studies. In coastal zones, the derivation of the bedload sediment transport rate and the flow velocity distribution is done by entropy theory which assumes the modified spatiotemporal disorder power index(MSTDPI) and the time-averaged flow velocity(as a random variable). Studying the deposition trend of bedload sediment transport rate for the sand particle(BLSTRS) and estimating the coastal erosion rate as a case study, the Makran coast is selected. To analyze the spatiotemporal patterns, the disorder power index(entropy-power) method is applied in this study where the monthly data of six Makran coastal sections from January 1970 to December 2015 are used. The studied data are mainly focused on the correlation of the flow rate of the sediment from the Makran River, and the spatiotemporal patterns of *** their meaningful spatiotemporal variability, it is not very easy to explain how the abovementioned variables perform together;the entropy-power index allows a better understanding of the combined performance of such parameters as the flow velocity and sediment transport by showing clearer signals for the assessment of coastal engineering issues at very large(coastal) scales.

关键词： flow velocity spatiotemporal entropy theory coastline zone

CTAB-assisted fabrication of hierarchical flower-like magnesium oxide adsorbent for enhanced removal performance towards phosphate

在线全文

学校读者我要写书评

暂无评论

Journal of Magnesium and Alloys 2023年第9期11卷 3231-3240页

作者： saeed Ahmed State Key Laboratory of Chemical Resource Engineering College of ChemistryBeijing University of Chemical TechnologyBeijing 100029China Department of Chemistry The University of LahoreLahore 54590Pakistan Department of Chemistry University of ChakwalPakistan

In this work, a series of hierarchical flower-like magnesium oxide(MgO) adsorbents were successfully fabricated in a cetyltrimethylammonium bromide(CTAB) assisted solvothermal route using hexamethylenetetramine(HMTA) as a precipitating agent. Effects of CTAB feeding amount on the structure, morphology, pore structure, and corresponding adsorption behavior were investigated. The hierarchical gardenias flower-like MgO demonstrated a surface area of 336.54 m^(2)·g^(-1) at a minimum ratio of the CTAB/Mg^(2+)was 0.02 in the reaction system. The hierarchical MgO phosphate removal capacity was 348.32 mg·g^(-1), which followed the pseudo-second-order and Freundlich isotherm model obtained from the large surface area and appropriate pore size. The value of n also suggests the feasible nature of phosphate adsorption under the examined conditions. Indeed, this CTAB assisted solvothermal method can provide a new understanding to tune the desired properties of a material by merely adjusting the reaction parameters of MgO.

关键词： Adsorption CTAB-assisted Magnesium oxide Phosphate removal Solvothermal

Computational analysis of the flow of pseudoplastic power-law fluids in a microchannel plate

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Engineering 2017年第10期25卷 1360-1368页

作者： saeed Mortazavi Department of Chemical Engineering Shahrood Branch Islamic Azad University Shahrood Iran

The flow of pseudoplastic power-law fluids with different flow indexes at a microchannel plate was studied using computational fluid dynamic *** velocity distribution along the microchannel plate and especially in the microchannel slits,flow pattern along the outlet arc and the pressure drop through the whole of microchannel plate were investigated at different power-law flow *** results showed that the velocity profile in the microchannel slits for low flow index fluids was similar to the plug flow and had uniform *** the power-law fluids with lower flow indexes had lower stagnation zones near the outlet of the microchannel *** pressure drop through the microchannel plate showed huge differences between the *** most interesting result was that the pressure drops for power-law fluids were very smaller than that of Newtonian *** addition,the heat transfer of the fluids through the microchannel with different channel numbers in a wide range of Reynolds number was *** power-law fluid with flow index(n=0.4),the Nusselt number increases continuously as the number of channels *** results highlight the potential use of using pseudoplastic fluids in the microheat exchangers which can lower the pressure drop and increase the heat transfer efficiency.

关键词： Power-law fluids Microchannel Pressure drop Flow distribution Heat transfer

Thermo-mechanical simulation of frost heave in saturated soils

在线全文

学校读者我要写书评

暂无评论

Frontiers of Structural and Civil Engineering 2023年第9期17卷 1400-1412页

作者： saeed VOSOUGHIAN Romain BALIEU Department of Civil and Architectural Engineering KTH Royal Institute of TechnologyStockholm 10044Sweden

Roads are exposed to various degradation mechanisms during their *** pavement deterioration caused by the surrounding environment is particularly severe in winter when the humidity and subfreezing temperatures *** heave-induced damage is one of the winter-related pavement *** occurs when the porewater in the soil is exposed to freezing *** study of frost heave requires conducting a multiphysics analysis,considering the thermal,mechanical,and hydraulic *** paper presents the use of a coupled thermo-mechanical approach to simulate frost heave in saturated soils.A function predicting porosity evolution is implemented to couple the thermal and mechanical field *** function indirectly considers the effect of the water seepage inside the *** frost heave scenarios with uniform and non-uniform boundary conditions are considered to demonstrate the capabilities of the *** results of the simulations indicate that the thermo-mechanical model captures various processes involved in the frost heave phenomenon,such as water fusion,porosity variation,cryogenic suction force generation,and soil *** characteristics and consequences of each process are determined and discussed ***,the results show that non-uniform thermal boundaries and presence of a culvert inside the soil result in uneven ground surface deformations.

关键词： frost heave multiphysics analysis thermo-mechanical approach saturated soils